Background:: Over the past few years, research ethics committees have increasingly demanded explicit consent before archival tissue samples can be used in research projects. Current UK guidance in this area requires an assessment of whether it is “practical” to obtain explicit consent. Ethics committees have little experience or evidence to help them to judge what is “practical” in this context.Methods:: We attempted to obtain general consent for research use of surplus tissue from renal transplant biopsies from the entire patient population (...) of the renal transplant unit in Leicester. The nature of this patient population would be expected to facilitate this task.Results:: A total of 495 letters were sent. Attempts were made to contact non-responders when they attended the outpatient clinic. One year after the initiation of the project, the opinions of 26% of the patients had still not been ascertained.Conclusions:: The results confirm that the vast majority of patients are happy for “surplus” biopsy material to be used for research; the situation does not parallel the use of autopsy tissue. A requirement to obtain explicit consent for the study of archival tissue is likely, however, to block or at least seriously delay research, which is contrary to the public interest and specifically may harm the interests of the patients concerned. In the UK, the problem of tissue being used against the wishes of the donor has now been largely replaced by the problem of prohibition of tissue use against the wishes of the donor. (shrink)

Politik soll ihre Entscheidungen nicht nur sachgerecht und gemäß den rechtlichen Rahmenbedingungen treffen, sondern ebenso den Ansprüchen der Moralität genügen. Anhand der vier Themen Moral, Terrorismus, Globalisierung und Demokratie zeigen renommierte Experten allgemeinverständlich auf, welche Herausforderungen damit für Politik und Ethik verbunden sind. Mit Beiträgen von Moritz Leuenberger, Herfried Münkler, Francis Cheneval und Julian Nida-Rümelin.

Andreas Hesselius and Pehr Kalm both spent time in eastern North America during the first half of the 18th century. Both came with an ardent desire to observe and learn about the natural environment and inhabitants of the region. Both produced writings, in the form of journals that have proved immensely useful to subsequent scholars. Yet their writings also display differences that illuminate the epistemological and sociological underpinnings of their observations, and which had consequences for their encounters with foreign environments. (...) Hesselius, who served as pastor to the Swedish congregation in Philadelphia from 1712 to 1724, described his experiences and observations with what we might call a historical awareness, while Kalm, known as the first of Linnaeus’s students to travel to the New World, primarily offered dehistoricized and denarrativized taxonomic ethnographic descriptions. At first glance, Hesselius and Kalm appear to illustrate perfectly Michel Foucault’s description of the difference between Renaissance and classical epistemologies. Kalm’s disembodied and decontextualized representations fit well with Foucault’s description of natural history in the classical age as consisting ‘of undertaking a meticulous examination of things themselves…and then of transcribing what it has gathered in smooth, neutralized, and faithful words’. This article, however, points out that while Hesselius and Kalm arrive at similar descriptions of plants and other-than-human beings by employing different methodologies, when it comes to describing indigenous peoples their respective methodologies lead to radically different approaches, with Hesselius writing them into history, while Kalm relegates them to ethnology in the sense of savage ‘peoples without histories’. (shrink)

Once we realize that the indivisible and infinitely repeatable One of the arithmetic lesson in Republic7 is generated by διάνοια at Parmenides 143a6-9, it becomes possible to revisit the Divided Line’s Second Part and see that Aristotle’s error was not to claim that Plato placed Intermediates between the Ideas and sensible things but to restrict that class to the mathematical objects Socrates used to explain it. All of the One-Over-Many Forms of Republic10 that Aristotle, following Plato, attacked with the Third (...) Man, are equally dependent on Images and above all on the Hypothesis of the One. (shrink)

Œuvres sans titre, sans auteur, les formes naturelles furent collectées à de nombreuses époques et dans différents lieux du monde. Universelles, elles apparaissent dans la diversité d'usages d'une pluralité de cultures comme les signatures matérielles d'invisibles forces, supports cultuels ou supports de contemplation, traits d'union entre le naturel et le surnaturel, le visible et l'invisible, mais surtout comme l'indice de préoccupations esthétiques. Ainsi Yves Le Fur cherche-t-il à comprendre ce que leur énigme révèle de notre regard sur les œuvres d'art"--Page (...) 4 of cover. (shrink)

Les démarches d’anticipation, tout comme le développement durable, sont tournées vers le futur. La montée en puissance des préoccupations du développement durable a engendré une multiplication de démarches d’anticipation conduites par les collectivités territoriales. Elle se traduit pour l’action publique par un double élargissement des échelles spatiale et temporelle des enjeux auxquels elle doit répondre, passant d’enjeux locaux et de court terme à des enjeux planétaires et de long terme. Si les démarches d’anticipation sont réceptrices de ces évolutions elles en (...) sont également vectrices, contribuant par les adaptations de leur pratique à une meilleure prise en compte des enjeux du développement durable. Bien que le chantier des améliorations à apporter à ces démarches soit encore ouvert, avec de nombreuses questions encore en suspens, il semblerait que la mobilisation des acteurs soit un préalable indispensable aux dynamiques de transition, à la condition de les maintenir dans le temps de manière souple et adaptable. (shrink)

In Western society bicycling is commonly perceived as either a sport, a form of leisure, an activity for children, or at best, a utilitarian transportation technology. In this paper, I contest these assumptions by discussing ways in which both bicycling and bicycle technologies are politicized as a response to the cultural, social and political norms of Western society. Through historical examples that include 19th century Socialists, 'first wave' feminists, and 1960's Dutch Anarchists, I provide a theoretical context in which one (...) can understand how present day activists appropriate the bicycle through a dialectic of action and communication. In short, I demonstrate how a seemingly neutral technology (the bicycle) and an everyday activity (bicycling can be utilized as tools for dissent, protest, and cultural critique. (shrink)

A study of the enormous influence of the writings of Friedrich Nietzsche on turn-of-the-century German literature. The aim of this book is to explore "that post-Nietzschean archipelago of German literature which no one mind can hope to map, let alone inhabit" (Michael Hamburger) and to introduce it to the English-speaking reader for the firsttime, in accessible form. The study starts from the assumption that the daring imagery and cosmic sweep of Thus Spake Zarathustra provided the impetus for the creation of (...) visionary epics and cosmological poetic universes. The book is original in that it presents for the first time a selection of writers hitherto regarded as impossible of access and reduces their epic scope to manageable proportions while preserving their essential meaning. Among thewriters treated are Alfred Mombert, Theodor Däubler, Rudolf Pannwitz, Ludwig Derleth, Alfred Schuler, Ludwig Klages, Christian Morgenstern, and the members of the Friedrichshagen Circle. Furness draws on the most recent scholarship and provides a fascinating account of a 'lost generation.' The book will be of interest to Nietzsche scholars, to students of Lebensphilosophie, and to those interested in German literature around the turn of the century. It will be of special interest to those drawn to the creation of myths and to radical religious thought. Raymond Furness is professor and former chair of German at St.Andrews University, Scotland. He has published widely on late nineteenth- and early twentieth-century German literature. (shrink)

This chapter contains sections titled: We're Not Blocking Traffic… Background and (Dis)organization Interpretations Influences and Impacts …We (Still) Are Traffic Notes.

A connection between Aristotle's syllogistic and the calculus of relations is investigated. Aristotle's and Gergonne's syllogistics are considered as some algebraic structures. It is proved that Gergonne's syllogistic is isomorphic to closed elements algebra of a proper approximation relation algebra. This isomorphism permits to evaluate Gergonne's syllogisms and also Aristotle's syllogisms, laws of conversion and relations in the "square of oppositions" by means of regular computations with Boolean matrices.

In a 1985 article entitled “The Art of Glaukos,” Diskin Clay suggested that the enigmatic passage at the beginning of the geological myth in Phaedoreferred toRepublic10, where the soul is likened to the sea-creature Glaucus whose true nature, like the soul’s, is obscured by the distortions imposed by underwater life. Starting with a defense of Clay’s ingenious suggestion, my purpose is to compare Phaedoto Glaucus, with its true nature obscured by traditional assumptions about the order in which Plato composed his (...) dialogues, and thus how they should be read. At least part of the reason that Clay’s thesis has not been embraced is because it clashes with the dogma that Phaedocannot refer back to Republic; I want to challenge that dogma. Borrowing from Catherine Zuckert the notion that, since Phaedocomes at the end of Socrates’ story, it can usefully be read as the culmination of the Platonic dialogues, I will show how a “late” Phaedo—i.e., a reading of the dialogue that is open to the possibility that it refers to more than one dialogue generally considered to be later than it with respect to composition—recovers its true nature, presently encrusted with the oysters and seaweed of an outdated developmentalism that has obscured this culminating masterpiece of Plato’s dramatic and philosophical art. (shrink)

This sweeping introduction to the science of virtual environment technology masterfully integrates research and practical applications culled from a range of disciplines, including psychology, engineering, and computer science.