There are two ways of preventing induced cellular mutagenesis. In the first, mutagens are inactivated by ‘desmutagens’ before they can attack the DNA. In the second, ‘bio‐antimutagens’ interfere with cellular fixation processes working on damage in DNA. Examples of modes of action are shown for these inhibitors of induced mutations and implications for reducing genetic damage in man are discussed.

Chomin Nakae (Japanese thinker,1847-1901) has been called “the Rousseau of the East” by both Japanese and Chinese because he translated Jean-Jacque Rousseau, for instance, the Social Contract into Japanese and Chinese. It would be natural to suppose that Chomin read Rousseau’s books as an overseas student in France from 1872 to 1874 after the time of “ the Paris Commune”. It seems that many Chinese overseas students in Japan read Rousseau’s books in Chinese and Japanese translated by Chomin and accepted (...) democratic and revolutionary thoughts originally born in the West and brought them home. Adding to the fact, it is insisted that the substance of Chomin’s thought is rather Confucian-biased democracy to be governed morally by both people and the sovereign than pure popular supremacy, which was gotten through examining the results of the recent research. (shrink)

Aesthetic emotions are elicited by different sensory impressions generated by music, visual arts, literature, theater, film, or nature scenes. Recently, the AESTHEMOS scale has been developed to facilitate the empirical assessment of such emotions. In this article we report a semantic profile analysis of aesthetic emotion terms that had been used for the development of this scale, using the GRID approach. This method consists of obtaining ratings of emotion terms on a set of meaning facets which represent five components of (...) the emotion process. The aims here were to determine the dimensionality of the GRID features when applied to aesthetic emotions and compare it to published results for emotion terms in general, and to examine the internal organization of the domain of aesthetic emotion terms in order to identify salient clusters of these items based on the similarity of their feature profiles on the GRID. Exploratory Principal Component Analyses suggest a four-dimensional structure of the semantic space consisting of valence, power, arousal, and novelty, converging with earlier GRID studies on large sets of standard emotion terms. Using cluster analyses, 15 clusters of aesthetic emotion terms with similar GRID feature profiles were identified, revealing the internal organization of the aesthetic emotion terms domain and meaningful subgroups of aesthetic emotions. While replication for further languages is required, these findings provide a solid basis for further research and methodological development in the realm of aesthetic emotions. (shrink)

Right-ear advantage refers to the observation that when two different speech stimuli are simultaneously presented to both ears, listeners report stimuli more correctly from the right ear than the left. It is assumed to result from prominent projection along the auditory pathways to the contralateral hemisphere and the dominance of the left auditory cortex for the perception of speech elements. Our study aimed to investigate the role of attention in the right-ear advantage. We recorded magnetoencephalography data while participants listened to (...) pairs of Japanese two-syllable words. The amplitudes of the stimuli were modulated at 35 Hz in one ear and 45 Hz in the other. Such frequency-tagging allowed the selective quantification of left and right auditory cortex responses to left and right ear stimuli. Behavioral tests confirmed the right-ear advantage, with higher accuracy for stimuli presented to the right ear than to the left. The amplitude of the auditory steady-state response was larger when attending to the stimuli compared to passive listening. We detected a correlation between the attention-related increase in the amplitude of the auditory steady-state response and the laterality index of behavioral accuracy. The right-ear advantage in the free-response dichotic listening was also found in neural activities in the left auditory cortex, suggesting that it was related to the allocation of attention to both ears. (shrink)

While empathy is considered a critical determinant of the quality of medical care, growing evidence suggests it may be associated with both one’s own positive and negative moods among healthcare professionals. Meanwhile, sense of coherence plays an essential role in the improvement of both psychological and physical health. Reportedly, individual SOC reaches full stability after around age 30. The aim of this study was first to evaluate the mediatory role of SOC on the association between empathy and individual moods among (...) 114 healthcare professionals in a general hospital, and then to examine the moderating effect of age on this association. Participants completed a range of self-report demographic questionnaires, Empathy Process Scale, the 13-item Antonovsky’s SOC, and Profile of Mood States. Findings showed that SOC mediated the relations between empathy and both POMS-Vigor and POMS-Depression. Notably, moderated mediation analysis revealed that there was a significant interaction on self-vigor mood in healthcare professionals. The indirect effect of empathy on self-vigor mood through SOC was significant at over mean age “32.83.” Although there was no significant interaction with age regarding the indirect effect of empathy on self-depression mood, in the sub-category level analysis of empathy, we found a significant interaction item [age × empathy for other’s negative affect ] on SOC. This indirect effect was also significant at over mean age “32.83.” Taken, together, the current study highlighted the significant mediator of SOC on that empathy amplifies self-vigor mood and attenuates self-depression mood as a protective factor among the Japanese healthcare professionals. Some components of these processes may depend on the moderating role of age, indicating that we may need to consider the SOC development with age for more effective empathy performance interventions among healthcare professionals. (shrink)

Glaubensbegrun̈dung ais Wahrheitsgeschehen, voir E. Biser.--Epikur und Karl Marx oder ein subjektiver Faktor im Fall der Atome, von E. bloch.--Empirismus in der Transzsndentalphilosophie von H. Braun.--Gedanken abselts der dichotomlschen Welterklar̀ung,von K. K. Cho.--Nietzsches Kritik der Moral und die Ansaẗze der existenzphilosophischer Ethik, von H. Fahrenbach.--Hegel ub̈er Nutzen und Nachtell der Philosophie fur̈ den Staart, von H. F. Fjulda.--Anmerkungen zu dem Thema "Hegel und Habermas.----von GH. G. Gadamer.--Arbeit und Internktion, von J. Habermas.--Zwischen Natur und Geschichte, von S. Hosoya.--Das Ende der (...) Unendlichkelt. von G. Knauss.--Historia Magistra Vitae, von R. Koselleck.--Die philosophische Situation selt kant, von G. Krug̈er.--Absolute Reflexion und Sprache, von W. Marx.--Hegel und Gans, von M. Riedel.--Die Moral zwischen Natur und Geschichte, von P. Rossi.--Bemerkungen zu Schopenhauer, von W. Schulz.--A Note on Lucretius, von L. Strauss.--Das Logische Nackte, von W. Szilasl.--Grundmotive der Sozialphilosophie Hegels, von E topitsch.--Zeit und Zeitlosigkelt in der Philosophie A. N. Whiteheads, von R. Wiehl.--Die Anfan̈ge der Phil. (shrink)