Fifty-seven years ago. Hiroshima and Nagasaki were annihilated by unprecedented state terrorism. But survivors of both cities never said "Remember Hiroshima and Nagasaki!" No survivors harbored the feeling "once recovered from devastation of the holy land, Japan will not fail to revenge". Instead, they realized in the atomic inferno that violence begets violence and pledged: "Rest in peace. We will never repeat the mistakes. No more Hiroshima, No more Nagasaki".

The aim of this paper is to call the attention, especially that of feminists, to the current progress in biology. It appears gender studies still confine themselves to outdated ideas of sex chromosomes like XX, XY (§10). However, science has been making progress. It no longer sticks to such matters as XX, XY. Its interest is now in Sry, a kind of gene (§11), and MIS, a kind of sex hormone (§14). Abnormalities of sex chromosomes are no longer evidence to (...) deny the biological approaches, for example. We shed light on this fact, putting gender studies in the context of chronologies of science as well (§§2-9). (shrink)

This article handles a series of articles written by Suzuki (2016a; 2016b; 2018), in which he put forward the anti-psychologism, a new standpoint of action theory. This standpoint, however, has lost the path Anscombe originally opened up, seemingly. Anscombe’s point (called “Anscombe’s motif” in this article) was: the agent him/herself responds, by revealing his/her original motive, to the question “Why did/do you do…?” Leaving this ground, in modern theories, one sees an unfamiliar idea like a normative reason flow into the (...) debate on human action. We review this academic environment critically in terms of Kaneko (2017), whom Suzuki criticized in one of his papers (2018). (shrink)

Paired associative stimulation at the spinal cord has been shown to increase muscle force and dexterity by strengthening the corticomuscular connection, through spike timing dependent plasticity. Typically, transcranial magnetic stimulation and transcutaneous peripheral nerve electrical stimulation are often used in spinal PAS. PNS targets superficial nerve branches, by which the number of applicable muscles is limited. Alternatively, a muscle can be activated by positioning the stimulation electrode on the “motor point”, which is the most sensitive location of a muscle to (...) electrical stimulation. Although this can increase the number of applicable muscles for spinal PAS, nobody has tested whether MPS can be used for the spinal PAS to date. Here we investigated the feasibility of using MPS instead of PNS for spinal PAS. Ten healthy male individuals received spinal PAS on two separate days with different stimulation timings expected to induce facilitation of corticospinal excitability or no effect on the soleus. The motor evoked potentials response curve in the soleus was measured prior to the spinal PAS, immediately after and at 10, 20, 30 min post-intervention as a measure of corticospinal excitability. The post-intervention MEP response curve areas were larger in the REAL condition than the CONTROL conditions. Further, the post-intervention MEP response curve areas were significantly larger than pre-intervention in the REAL condition but not in the CONTROL condition. We conclude that MPS can facilitate corticospinal excitability through spinal PAS. (shrink)

Pyridoxal 5′‐phosphate, the vitamin B6 derivative, acts as the coenzyme of many enzymes involved in amino acid metabolism. Exceptionally, this compound was found covalently bound to glycogen phosphorylase, the key enzyme in the regulation of glycogen metabolism. Although it is essential for the function of phosphorylase, its direct role has remained an enigma. We have recently found that the glucose moiety of pyridoxal (5′)diphospho (1)‐α‐D‐glucose, a conjugate of pyridoxal 5′‐phosphate and glucose 1‐phosphate through a pyrophosphate linkage, is transferred to the (...) nonreducing end of glycogen, forming a new α‐1,4‐glucosidic linkage. This finding emphasizes the importance of the direct phosphate‐phosphate interaction between the coenzyme and the substrate in the phosphorylase catalytic reaction. We have proposed a catalytic mechanism for phosphorylase in which the phosphate group of pyridoxal 5′‐phosphate acts as an electrophile to the phosphate group of glucose 1‐phosphate. This appears to represent the first instance of the direct involvement of a phosphate group in catalysis by enzymes. (shrink)

判然としないその姿ゆえに、哲学史の表舞台に立つことがなかった「個」。アリストテレスからアウグスティヌス、トマス・アクィナス、エックハルト、スコトゥス、ライプニッツ、レシニェフスキまで。それぞれの思想に 8人の専門家が光をあて、「個」の歴史を浮かび上がらせるわが国で初めての試み。.

Although written in Japanese, what the statistical inference is philosophically investigated.

The aim of this paper is to clarify the relationship of three thinkers, Hume, Bentham, and Mill in the context of utilitarianism. Through discussion, we shall figure out how and why utilitarianism is trustworthy.

Although written in Japanese, 意志・格率・道徳法則（Will, Maxim and the Moral Law）pursues the logical connection of these Kantian tools in ethics. Note: the structure of the uploaded document is not the same as the published one.

Although written in Japanese, 経験的綜合判断の一般的形式（The General Form of Empirical Synthetic Judgement）pursues the general logical form of the Kantian empirical synthetic judgements.

Addressing the question in the form of Kant’s maxim, this paper moves on to a more controversial topic in biomedical ethics, physician-assisted suicide. However, my conclusion is tentative, and what is worse, negative: I partially approve suicide. It does not imply a moral hazard. The situation is opposite: in the present times, terminal patients seriously wish it. I, as an author, put an emphasis on this very respect. Now suicide is, for certain circles, nothing but justice. The arguments of thinkers (...) who approve suicide are also cited from this angle. (shrink)

This paper is devoted to defending philosophical studies of mind, especially traditional ones. In my view, human mentality is a dialogue with myself, which has a social aspect that is never explained nor predicted by scientific studies. We firstly derive this picture from Descartes’ classical argmuments (§§2-3), and then develop it in the context of Kantian ethics (§4). Some readers think this combination arbitrary. However, these two philosophers agree on mind/body dualism (§5), and further, the fact that the dialogue is (...) often made in an ethical situation leads us to Kantian ethics. We shall draw this developed picture within the format of modern practical syllogisms (§§5-13). Finally, we shall refer to Nick Zangwill’s normative essentialism for the completion of our whole picture (§§7-8). (shrink)

LK is much more difficult than NK, and to make matters worse, Gentzen's intention is still unclear when it comes to that system (LK). -/- This book, Vol.1 of the series titled What is LK?, tackles this issue, focusing on the sequent, the most enigmatic notion we find in LK. The dependence-relation we find in NK shall play a crucial role in that investigation. -/- The style is typically textbook-like, so readers can learn the system of LK, using this series (...) as a guidance, too. (shrink)

LK is much more difficult than NK, and to make matters worse, Gentzen's intention is still unclear when it comes to that system (LK). -/- The second and third volumes of the series titled What is LK? conduct the detailed survey of each inference-figure in a toe-to-toe way, as it were, which most mathematicians looked through. -/- The present volume, Vol.2, looks deeper into structural inference-figures, which is never an easy task.

LK is much more difficult than NK, and to make matters worse, Gentzen's intention is still unclear when it comes to that system (LK). -/- The second and third volumes of the series titled What is LK? conduct the detailed survey of each inference-figure in a toe-to-toe way, as it were, which most mathematicians looked through. -/- The present volume, Vol.3, looks deeper into those operational inference-figures which concerns propositional logic.