L'édification spatio-temporelle dont se sert un observateur isolé pour représenter ses résultats de mesures comporte la construction d'un espace physique qui, quoique non catégorique, est applicable sur l'espace euclidien à trois dimensions. Aucun argument ne permet de décider si l'espace est euclidien ou non euclidien. Les expériences permettent seulement à l'observateur d'affirmer que l'espace est pratiquement euclidien en son voisinage.

Background In the context of limited health care budgets in countries where Neglected Tropical Diseases are endemic, scaling up disease control interventions entails the setting of priorities. However, solutions based solely on cost-effectiveness analyses may lead to biased and insufficiently justified priorities. Objectives The objectives of this paper are to 1) demonstrate how a range of equity concerns can be used to identify feasible priority setting criteria, 2) show how these criteria can be fed into a multi-criteria decision-making matrix, and (...) 3) discuss the conditions under which this decision-making procedure should be carried out in a real-world decision-making context. Methods This paper draws on elements from theories of decision analysis and ethical theories of fair resource allocation. We explore six typical NTD interventions by employing a modified multi-criteria decision analysis model with predefined criteria, drawn from a priority setting guide under development by the WHO. To identify relevant evidence for the six chosen interventions, we searched the PubMed and Cochrane databases. Discussion Our in vitro multi-criteria decision analysis suggested that case management for visceral leishmaniasis should be given a higher priority than mass campaigns to prevent soil-transmitted helminthic infections. This seems to contradict current health care priorities and recommendations in the literature. We also consider procedural conditions that should be met in a contextualised decision-making process and we stress the limitations of this study exercise. Conclusion By exploring how several criteria relevant to the multi-facetted characteristics of NTDs can be taken into account simultaneously, we are able to suggest how improved priority settings among NTDs can be realised. (shrink)

BackgroundIn the context of limited health care budgets in countries where Neglected Tropical Diseases (NTDs) are endemic, scaling up disease control interventions entails the setting of priorities. However, solutions based solely on cost‐effectiveness analyses may lead to biased and insufficiently justified priorities.ObjectivesThe objectives of this paper are to 1) demonstrate how a range of equity concerns can be used to identify feasible priority setting criteria, 2) show how these criteria can be fed into a multi‐criteria decision‐making matrix, and 3) discuss (...) the conditions under which this decision‐making procedure should be carried out in a real‐world decision‐making context.MethodsThis paper draws on elements from theories of decision analysis and ethical theories of fair resource allocation. We explore six typical NTD interventions by employing a modified multi‐criteria decision analysis model with predefined criteria, drawn from a priority setting guide under development by the WHO. To identify relevant evidence for the six chosen interventions, we searched the PubMed and Cochrane databases.DiscussionOur in vitro multi‐criteria decision analysis suggested that case management for visceral leishmaniasis should be given a higher priority than mass campaigns to prevent soil‐transmitted helminthic infections. This seems to contradict current health care priorities and recommendations in the literature. We also consider procedural conditions that should be met in a contextualised decision‐making process and we stress the limitations of this study exercise.ConclusionBy exploring how several criteria relevant to the multi‐facetted characteristics of NTDs can be taken into account simultaneously, we are able to suggest how improved priority settings among NTDs can be realised. (shrink)

Background and objectives: Summary measures of overall health inequality are independent of group membership and enable international comparisons of distribution of health. We compare inequality between and within countries over time and identify normative issues underlying such comparisons. Methods: We used a set of modeled historical life tables for 193 World Health Organization member states from the years 1990, 2000 and 2008 and calculated inequality in age at death and inequality-adjusted life expectancy. Results: Our calculations suggest that overall health inequalities (...) in age at death have been decreasing in the period 1990–2008 in most countries of the world. Only 20 countries experienced increasing distribution in age at death. Simultaneously, overall life expectancy has increased in 85 per cent of all countries. Thus, the combined measure IALE has improved globally. The same overall trend of reduced health inequality applies to all groups of countries stratified by income level. Conclusion: Overall health inequalities, in addition to average health outcomes, could be reported regularly to monitor the health status of populations and the performance of health systems. We find, on normative grounds, the combined measure IALE to be preferable to measuring trends in inequality only. Likewise, we find the Absolute GiniH to be preferable to Relative GiniH. (shrink)

Trainers often use information from previous learning sessions to design or redesign a course. Although universities conducted numerous research integrity training in the past decades, information on what works and what does not work in research integrity training are still scattered. The latest meta-reviews offer trainers some information about effective teaching and learning activities. Yet they lack information to determine which activities are plausible for specific target groups and learning outcomes and thus do not support course design decisions in the (...) best possible manner. This article wants to change this status quo and outlines an easy-to-use taxonomy for research integrity training based on Kirkpatrick’s four levels of evaluation to foster mutual exchange and improve research integrity course design. By describing the taxonomy for research integrity training (TRIT) in detail and outlining three European projects, their intended training effects before the project started, their learning outcomes, teaching and learning activities, and their assessment instruments, this article introduces a unified approach. This article gives practitioners references to identify didactical interrelations and impacts and (knowledge) gaps in how to (re-)design an RI course. The suggested taxonomy is easy to use and enables an increase in tailored and evidence-based (re-)designs of research integrity training. (shrink)

Toute sa vie, Jean Guitton s'est abondamment raconté, avec parfois une grande complaisance. De ce fait il a laissé dans l'ombre certains épisodes de sa vie, comme l'arbitrage suite à l'occupation de l'église Saint-Nicolas-du-Chardonnet, ou la mission auprès de monseigneur Lefebvre, demeurés infructueux. L'auteur, neveu de l'académicien, donne son éclairage sur ces circonstances, en vue de contribuer à son portrait. À partir d'archives familiales il traite de son amour passionné pour la vallée de la Tardes, en Creuse, dans laquelle il (...) a situé le portrait de sa mère, des relations très étroites avec son frère Henri, de son expérience de la chose militaire, de son parcours universitaire, avec la douloureuse épreuve de l'Épuration, et de sa fièvre verte académique. Il évoque ses flirts avec des illustres. Il raconte un certain nombre de souvenirs familiaux, avec quelques précisions sur sa vie quotidienne. Ainsi il apporte des éléments pour une future biographie plus complète d'un homme, sans doute surdoué, très habile et très attachant, qui devrait laisser une trace dans l'histoire."--Page 4 of cover. (shrink)

Si le xixe siècle fut le temps de l’émergence de la figure de la “ grande voyageuse ”, on ne saurait surestimer cette innovation. La hiérarchie des genres de récits de voyage, l’importance du contre-exemple britannique, la condamnation morale de la voyageuse solitaire manifestent assez le sentiment de l’illégitimité du voyage féminin. Pourtant, pèlerines, valétudinaires et touristes se multiplièrent dans un siècle qui fut aussi celui de l’invention du voyage de noces. Cet article tente de prendre la mesure de l’ensemble (...) des normes qui ont alors commandé les pratiques, nombreuses et variées, du voyage féminin. (shrink)

V.2. Les grandes évasions esthetiques; Delacroix, Flaubert, les Goncourt, Lamartine, Sarcey, Wagner. V.3. L'économie des passions; Mme Ackermann, Balzac, Hugo, Musset, Nietzsche, Sand, Zola.

V.2. Les grandes évasions esthetiques; Delacroix, Flaubert, les Goncourt, Lamartine, Sarcey, Wagner. V.3. L'économie des passions; Mme Ackermann, Balzac, Hugo, Musset, Nietzsche, Sand, Zola.

Voir ce qu’on ne devrait pas découvrir semble associé dans notre culture à une malédiction qui frappe celui qui outrepasse l’interdit. Les thérapies psychanalytiques de groupe réintroduisent ce que la psychanalyse, conçue comme une relation spécifique à deux, avait écarté : la pluralité, le face-à-face et le regard. Dans les thérapies analytiques de groupe peut-on perdre de vue que se met en scène et se théâtralise la problématique du lien? Ce qui ne nous regarde pas, c’est littéralement ce qui nous (...) tourne le dos et donc oblige à regarder à côté pour adopter un regard oblique et découvrir ce que révèle ici un regard sur les anamorphoses. (shrink)