Introduction:Despite being considered as a contravention under some countries’ legislation, the therapeutic use of Cannabis sativa has been growing in Brazil, due to the promising results observed in many pathologies. Such a scenario has fostered the need to deepen discussions on the subject and possibly revise legislation governing the substance use and access.Objectives:Identify the types of stigma related to the therapeutic use of Cannabis and describe the strategies people use to overcome stigma.Methods:This integrative review was carried out in the databases (...) PubMed, Scopus, CINAHL, MEDLINE, PsycINFO, Web of Science, and Cochrane Library, with 565 articles being retrieved. Triads’ cross-check were done, first maintaining the “cannabis” and “therapeutic use” pair, added by “stigma,” “bioethics,” “ethics,” “social consequences,” and “legal consequences.” The final selection resulted in six articles.Ethical Consideration:However, the ethical issues that pervade and regulate decisions on this subject must be considered.Results:Different dimensions and types of stigma related to the therapeutic use of Cannabis have been identified. The bioethical principle of autonomy was an expression of citizenship and human rights, mitigating internal conflicts related to self-stigma and the effects of external stigma on the person’s life.Conclusion:It was possible to identify the types of stigma related to the therapeutic use of Cannabis is an internal dimension represented and an external dimension, represented and to identify strategies adopted to face this stigma: skills training group for users, elaboration of laws and specific programs to clarify the therapeutic use of Cannabis with a greater social scope, and support for family members. Thus, contributing to the building of people’s autonomy in a broader context of decision-making autonomy and executive autonomy will provide the development of people’s capacity to perform complex tasks of self-management and, consequently, to continue promoting and preserving their decision-making process and their capacity to plan and perform tasks associated with managing their lives and their treatments. (shrink)

Ethical concerns about randomising persons to a no-treatment arm in the context of Ebola epidemic led to consideration of alternative designs. The stepped wedge design, in which participants or clusters are randomised to receive an intervention at different time points, gained popularity. Common arguments in favour of using this design are when an intervention is likely to do more good than harm, all participants should receive the experimental intervention at some time point during the study and the design might be (...) preferable for practical reasons. We examine these assumptions when considering Ebola vaccine research. First, based on the claim that a stepped wedge design is indicated when it is likely that the intervention will do more good than harm, we reviewed published and ongoing SW trials to explore previous use of this design to test experimental drugs or vaccines, and found that SW design has never been used for trials of experimental drugs or vaccines. Given that Ebola vaccines were all experimental with no prior efficacy data, the use of a stepped wedge design would have been unprecedented. Second, we show that it is rarely true that all participants receive the intervention in SW studies, but rather, depending on certain design features, all clusters receive the intervention. Third, we explore whether the SW design is appealing for feasibility reasons and point out that there is significant complexity. In the setting of the Ebola epidemic, spatiotemporal variation may have posed problematic challenges to a stepped wedge design for vaccine research. Finally, we propose a set of points to consider for scientific reviewers and ethics committees regarding proposals for SW designs. (shrink)

The nature of the relationship between the two types of meiotic recombination outcomes, exchange (crossing‐over) and simple gene conversion, has been debated for years. I here propose that these two types of events are not necessarily causally related and hypothesize that the primary role of events detected as simple gene conversion is in the recognition of homology during synapsis.

In Italy, consent for health treatment, aside from being an ethical and deontological obligation, constitutes an essential requirement for any medical treatment according to articles 13 and 32 of the National Constitution and also in accordance with the Council of Europe's ‘Convention on Human Rights and Biomedicine’. An essential requirement for the validity of consent is that clear, exhaustive and adequate information be provided to the patient himself: the practice of informed consent is a communicative relationship in which the patient (...) can express doubts, perplexities and clarification requests to the dentist. Furthermore, dental treatment has specific peculiarities: the relationship between dentistry and aesthetics, the concomitant presence of pathologies requiring different treatments, the elongated care process and the establishment of a trustworthy relationship and familiarity with the patient represent important aspects in the configuration of the dentist-patient relationship and in the process of acquiring informed consent. The dentist must offer correct information on diagnosis, prognosis, the therapeutic perspective and the likely consequences of therapy, alternative therapy and refusal of therapy, as well as eventual commitments for the period after treatment. Particular consideration must be given to minors and patients of unsound mind: the dentist's approach to these patients needs to be clear and appropriate to the person's age and understanding ability, even if the decisional power for sanitary treatment may be in the hands of a third person. (shrink)

A partir da implantação da República, surgiu um movimento de intelectuais que procurou congregar e dinamizar num esforço comum os pensadores de várias áreas do conhecimento, através da revista A Águia, tendo em vista uma nova ordem moral e cívica dentro do ideal democrático. Procurámos dar a conhecer as linhas principais que consubstanciaram o espaço aberto pela revista, as influências recebidas e os debates que a animaram.

Facial information is a powerful channel for human-to-human communication. Characteristically, faces can be defined as biological objects that are four-dimensional (4D) patterns, whereby they have concurrently a spatial structure as well as temporal dynamics. The spatial characteristics of facial objects possess three dimensions (3D), namely breadth, height and importantly, depth. The temporal properties of facial objects are defined by how a 3D facial structure evolves dynamically over time; where time is referred to as the fourth dimension (4D). Our entire perspective (...) of another’s face, whether it be social, affective or cognitive perceptions, is therefore built on a combination of 3D and 4D visual cues. Counterintuitively, over the past few decades of experimental research in psychology, facial stimuli have largely been presented to participants as a spatial pattern that has been flattened into two dimensions (2D), while remaining largely static. The following review aims to advance and update facial researchers, on the recent revolution in computer-generated, realistic 4D facial models produced from real-life human subjects. We delve in-depth to summarize recent studies which have utilized facial stimuli that possess 3D structural cues (geometry and depth) and 4D temporal cues (3D structure + dynamic viewpoint and movement). In sum, we have found that higher-order perceptions such as identity, gender, ethnicity, emotion and personality, are critically influenced by the 4D characteristics embedded within natural human faces. In future, it is recommended that facial stimuli incorporate the 4D space-time perspective with the proposed time-resolved methods. (shrink)

The processing of sensitive information in the health field is subject to rigorous standards that guarantee the protection of information confidentiality. Recently, the Italian Data Protection Authority (Garante per la Protezione dei Dati Personali) stated their formal opinion on a standard procedure in dental offices involving the submission of a questionnaire that includes the patient's health status. HIV infection status is included on the form. The Authority has stated that all health data collection must be in accordance with the current (...) Italian normative framework for personal data protection and respect the patient's freedom. This freedom allows the patient to decide, in a conscious and responsible way, whether to share health information with health personnel without experiencing any prejudice in the provision of healthcare requested. Moreover, data collection must be relevant and cannot exceed the principles of treatment goals with reference to the specific care of the concerned person. However, the need for recording information regarding HIV infection at the first appointment, regardless of the clinical intervention or therapeutic plan that needs to be conducted, should not alter the standard protection measures of the healthcare staff. In fact, these measures are adopted for every patient. (shrink)

Recently, an increasing number of researchers in different parts of the world have been studying childhood from a point of view that highlights children who are considered “peripheral” – far from the ideal model associated with Western countries. We began with the intention of getting to know African children in Angola, informed by the belief that the preservation of languages is important in maintaining social knowledge and traditions. This text describes a preliminary study carried out in a culturally rich location (...) with strong traditions, but which is also marked by processes of cultural denial and devaluation. According to Ndombele and Timbane (2020), most Angolan children learn Portuguese at age seven, when they start school, especially in rural areas. This fact hinders the literacy learning process, and presents the risk of the disappearance of some native languages. Many schools teach children only in Portuguese. When visiting a school in Ganda, a rural area of Benguela, we found a group of children who, primarily through the games they played, keep the Umbundu language alive, and with that the identity and culture of their ancestors. Building on this, these children and their teachers created a syllable association game based on the music sung as they played. The game had two modalities - in the Umbundu language and in the Portuguese language – and functioned as a bilingual pedagogical tool. In the initial moment of offering the game for testing with the children, it was discovered that by singing the song of the game and discussing the possible solutions by themselves, they were able to make correct associations of the syllables in Umbundu, which they then translated into Portuguese. Thus, a resource was created together with the teachers, which, in addition to valuing the native language of the population, allowed the use of children's knowledge to create a didactic resource. In addition, it was possible to encounter the concept of childhood in the current world, deconstructing the idea of a single and ideal model, especially in light of those children who bring habits from home that do not always harmonize with the school routine, and often clash with Euro/Western model, which is based on age separation of classes as a requirement to guarantee learning, and tend to devalue other exchanges that help children learn. (shrink)

THEODOR GOMPERZ AND JOHN STUART MILL The subject of this essay is the little known episode of an unusual friendship. To the writer its fascination lies as ...

Neste trabalho nos ocupamos centralmente em compreender a proposta ética de Hans Jonas e como ele apresenta o Princípio Responsabilidade como uma categoria ética a ser norteadora das ações humanas. Apresentamos um breve histórico do desenvolvimento da Filosofia da Tecnologia enquanto uma disciplina filosófica específica e, então, discutimos as principais considerações de Jonas sobre a necessidade de uma ética inteiramente nova que tome a técnica como objeto e a proposta que este apresente de uma ética do futuro pautada na responsabi (...) lidade enquanto princípio. (shrink)

Following the COVID-19 pandemic, many countries worldwide have put lockdowns in place to prevent the virus from spreading. Evidence shows that lockdown measures can affect mental health; it is, therefore, important to identify the psychological characteristics making individuals more vulnerable. The present study aimed, first, to identify, through a cluster analysis, the psychological attributes that characterize individuals with similar psychological responses to the COVID-19 home confinement; second, to investigate whether different psychological characteristics, such as personality traits, alexithymia, and resilience, specifically (...) influence anxiety, stress, and depression, depending on the scope of the confinement. We analyzed data from 393 participants who completed an online survey on their experiences during two different phases of the Italian lockdown, characterized by more or less strict measures of confinement. Two clusters were identified which included participants reporting a better and worse emotional response to the lockdown, respectively. Individuals in the −ER group showed lower emotional stability, resilience, and higher alexithymia. Moreover, even if lifting part of the restrictions decreased psychological distress among all participants, a reduction in perceived stress was observed only among individuals with high resilience. Finally, personality traits, alexithymia, and resilience differently affected depression, anxiety, and stress. Our results suggest that different psychological interventions should be planned depending on the context: mental health professionals should focus on enhancing the individuals’ coping strategies to alleviate stress in emergencies, while long-term intervention aiming at alleviating anxiety and depressive symptoms should focus on alexithymic tendencies and personality constructs. (shrink)

Review & Reply. Review of Gonçalves, R.T. (tr.) Lucrécio. Sobre a Natureza das Coisas(2021).

Este artigo parte do entendimento de que a cientificidade na pedagogia exigiu desta área do conhecimento suprimir a experiência como elemento vital da formação do homem, enquanto elevava a comprovação e regularidade do experimento ao patamar de destaque nos seus processos. A partir desta consideração, pretende-se tratar da transformação do conceito de experiência no campo educativo. Inicialmente, abordam-se as questões relacionadas à terminologia e significação do conceito “experiência” e sua possível transformação em “experimento”, e os desdobramentos dessa transição no campo (...) pedagógico. Na sequência, analisa-se a transformação do valor da experiência que passa a ser reconhecida enquanto experimento científico aplicado à pedagogia. Para tanto, apresenta-se, a partir da leitura da literatura educacional especializada, sobretudo os manuais dedicados à formação de professores, como é abordada a temática da Pedagogia Científica, ou seja, a construção dos discursos acerca da modernização da educação por meio de obras que apresentaram expressiva circulação no Brasil durante século XX. Dentre os resultados foi possível apreender o estabelecimento de uma pedagogia do experimento, ou, em outros termos, uma biopsicopedagogia como modelo estruturante do campo teórico da pedagogia com repercussão na formação de professores, e na predominância da problemática do ensino e da aprendizagem, ou seja, a intervenção metodológica em detrimento da formação integral do homem. Por fim, chega-se à conclusão de que se está, de um lado, diante dos impeditivos de realização da experiência e, de outro lado, diante de uma demanda, cada vez mais presente, de romper com o modelo pedagógico da modernidade, rumo aos novos desafios da educação de um homem que não se deixa mais ser, simplesmente, formado. Palavras-chave: Experiência. Experimento. Educação. Pedagogia. (shrink)

Os processos de integração regional em curso hoje na América Latina têm sido marcados por uma lógica territorial que tem concebido grandes áreas do espaço geográfico latino-americano como “vazios demográficos” ou “terras disponíveis”. Essa forma de conceber o espaço geográfico latino-americano remonta ao legado colonial que atravessa a formação sócio-espacial da região e a própria posição que o continente americano ocupou no processo de formação do sistema-mundo moderno-colonial, a partir de 1492. Este artigo tem por objetivo problematizar os processos de (...) integração física em curso atualmente no continente, especificamente a Iniciativa para Integração da Infra-estrutura Regional Sul-Americana (IIRSA), buscando evidenciar a reprodução da lógica da colonialidade do poder e do saber constituintes de seu modelo de desenvolvimento regional. (shrink)

O presente artigo trata da geografia da violência urbana na cidade do Rio de Janeiro. Mostra como a ação do Estado está permeada por ignorâncias acerca das lógicas de experiências espaciais com que se organizam e operam as classes populares trabalhadoras do Rio de Janeiro. O objetivo é estimular uma discussão que impulsione as análises para além dos discursos estigmatizadores com relação à população favelada. A metodologia adotada assemelha-se às sinuosidades dos becos e vielas, visto que optamos em nos entranhar (...) empiricamente na concretude do espaço favelado e, também, nas re-leituras das narrativas marginalizadas, dos compositores que há décadas oferecem pistas para que possamos esboçar um mapeamento das lógicas de sociabilidades e das experiências de espaço dessa população. Assim, podemos afirmar – ainda que hipoteticamente – que os mecanismos convencionais de análises e os instrumentos metodológicos fundamentados no distanciamento dos seus “objetos” são insuficientes para uma mínima compreensão do que se passa nos cotidianos de opressão e resistências das classes populares. O máximo que se tem alcançado historicamente, tanto com as pesquisas quantitativas acerca do tema quanto com os apelos midiáticos, é a forte influência na construção de discursos universalistas que naturalizam a criminalização dos citadinos mais pobres e as suas lógicas de integração-sobrevivência nas cidades. (shrink)

El artículo versa sobre la relación entre epistemes, espacio y poder. Cuestiona la presunción de universalidad tal como es pensada por la tradición hegemónica europea -eurocentrismo- pero rechaza cualquier pretensión de universalidad unidireccional venga de donde venga. Propone la idea de múltiples universalidades posibles partiendo del supuesto de la incompletud de toda cultura. El artículo invita a la crítica de la colonialidad del saber y del poder que están imbricados mutuamente, y a la atención que debemos prestar al lugar de (...) enunciación de cada discurso, lugar al mismo tiempo social y geográfico. Parte del pensamiento subalterno y valoriza los espacios de conflicto como epistémicamente densos, aportando además que el debate acerca de los territorios quizás sea la mejor expresión de la naturalización de las relaciones sociales y de poder que el territorio comporta, significando, en verdad, cuán profundas son las transformaciones en curso en los días actuales. (shrink)

El artículo procura analizar el contexto en que surge el reciente debate acerca de agua identificando los principales protagonistas que vienen conformando ese campo que es, al mismo tiempo, teórico, técnico y político. Demuestra como los organismos multilaterales y sus intelectuales (con el discurso de la escasez) vienen impulsando políticas que buscan transferir el papel del Estado en beneficio de los agentes empresariales estimulando procesos de privatización de agua y de su mercantilización. El artículo presenta una serie de casos en (...) que este proceso de privatización aumenta los conflictos en torno del agua. (shrink)

El artículo busca explicar las razones de la conversión al discurso de la sustentabilidad, por parte del sector de los grandes productores de petróleo y el de los latifundios empresariales de monocultivos, que hegemonizan el agro negocio. Para ello, se analiza la forma como históricamente se ha constituido el bloque de poder hegemónico conformado como un complejo de poder técnico-científico-industrial-financiero-militar-mediático, del cual también participan los dueños de los agronegocios -el viejo bloque de poder modernizado. Se concluye que se avecina una (...) verdadera tragedia con la expropiación generalizada que advendrá de la expansión del monocultivo latifundista moderno-colonial de los agro negociantes que quieren someter la producción agrícola a la producción de combustibles de biomasa. Se señala la enorme importancia de comprender adecuadamente el carácter mundial del capitalismo y del papel del desarrollo de las fuerzas productivas que el capital impone al mundo y la necesidad de ejercer el derecho a la diferencia anclada en la defensa del territorio. (shrink)

In this article it is defended that the notion known as “The mark of the cognitive” is better characterized as a process that performs the function of generating intelligent behavior, in a flexible and adaptive way, capable of adapting to circumstances, given it is a context sensitive process. For that, some relevant definitions of cognition are examined. In the end, it is pointed out that the definition of the mark of cognition as a context-sensitive process takes into account several factors (...) that were added as constitutive parts of cognitive phenomena over the years, especially the 4E Cognition, which cannot be satisfactorily accommodated alongside the preceding notions of cognition. Accordingly, this essay shouldn’t be mistaken merely as an exercise in intellectual history, but as a brief and accessible attempt to advance the debate. (shrink)

Nowadays and worldwide, the attention is focused on coronavirus disease, and its consequences on mental health are yet to be fully understood. It is important to capture differences in anxiety levels among populations, groups, and the gender-related variation. Therefore, the present study had two main purposes: to characterize the levels of state anxiety and trait anxiety by examining gender-related, sleep-related, and physical activity-related variations in a nonrepresentative sample of the Portuguese population during the first weeks of lockdown; and to explore (...) the possible relationship between trait anxiety and state anxiety and the possible role of gender as a moderator. This cross-sectional study comprised 1,332 Portuguese adults recruited online during COVID-19 outbreak measures. Participants answered to sociodemographic data and the Portuguese version of the State-Trait Anxiety Inventory. Gender differences were found in both state anxiety and trait anxiety with females presenting higher values. People reporting doing more physical activity than usual during COVID-19 lockdown presented lower levels of state anxiety. People reporting more satisfaction with the quality of sleep presented lower levels of both state anxiety and trait anxiety. Variation associated with the physical activity level was significantly different among groups in both state anxiety and trait anxiety. When analyzing in more detail separating the levels of physical activity, participants performing moderate and high physical activity showed lower values of state and trait anxiety compared to participants with low physical activity. Participants performing high physical activity also showed lower values of state anxiety compared to participants performing moderate physical activity. Higher levels of trait anxiety were related to higher levels of state anxiety, but this association was not moderated by gender. Interventions aiming to support people psychologically during this outbreak should consider anxiety as well as gender and possible behavioral changes in sleep and physical activity, for example. Health professionals should not only consider the anxiety related to the situation we are living but also address trait anxiety to help overcome COVID-19 psychological consequences. (shrink)

Background Doctors often deal with end-of-life issues other than assisted death, such as incompetent patients and treatment withdrawal, including food and fluids. Methods A link to a questionnaire was sent by email three times, at one-week intervals, to the doctors registered in the Northern Section of the Portuguese Medical Association. Results The questionnaire was returned by 1148 (9%) physicians. This study shows that only a minority of Portuguese doctors were willing to administer drugs in lethal doses to cognitively incompetent patients (...) at the request of a family member or other close person, and even less would do it on their initiative. Most doctors favored the withdrawal of life support measures in advanced and progressive diseases at the patient’s request. Still, much fewer doctors agreed with the suspension of supportive life measures at the request of a family member, another close person, or by their own unilateral decision. However, fewer agreed with that action concerning the rest of the food and fluids. Portuguese doctors favor the administration of drugs for suffering control, even foreseeing they could shorten life. Conclusion Most doctors in this study respect patients’ autonomy but disagree with measures decided by others that have an impact on patients’ survival. They also agree with the administration of drugs for suffering control, even considering the possibility of shortening life. (shrink)

Este artigo apresenta três teses fundamentais desenvolvidas por Friedrich Schelling em seu sistema de Filosofia da Natureza : A primeira responde à questão levantada por Kant sobre a possibilidade da construção na filosofia; a segunda baseia-se na interpretação do jovem Schelling sobre a teoria platônica sobre a criação da natureza; a terceira afirma a produtividade da natureza, com inspiração no conceito spinosana de natura naturans.

The world of work has been severely affected by the COVID-19 pandemic due to the high instability observed in the labor market, bringing several new challenges for leaders and employees. The present study aims to analyze the role of organizational and job resources in predicting employees’ job insecurity during the first wave of the COVID-19 outbreak, through the mediating role of work engagement. A sample of 207 Portuguese employees participated, of which 64.7% were women. Data was collected using an online (...) survey, including self-report measures of organizational resources, job resources, job insecurity, and work engagement. Data showed that job and organizational resources negatively influenced job insecurity. Moreover, work engagement was a significant mediator of the relation between performance feedback and job insecurity. Findings suggest that investing in job and organizational resources can act as protective factors to minimize feelings of job insecurity. Likewise, leaders should foster work engagement among employees to help them balance the relation between these resources and job insecurity, especially in crisis situations. Overall, this study takes a new, underexplored perspective, theoretically bridging organizational and job resources with job insecurity and work engagement during a time of great uncertainty, such as the COVID-19 pandemic. (shrink)

Schizophrenia is usually described as a fragmentation of subjective experience and the impossibility to engage in meaningful cultural and intersubjective practices. Although the term schizophrenia is less than 100 years old, madness is generally believed to have accompanied mankind through its historical and cultural ontogeny. What does it mean to be “mad”? The failure to adopt social practices or to internalize cultural values of common sense? Despite the vast amount of literature and research, it seems that the study of schizophrenia (...) and of the psychoses is suffering from a generic disintegration. In this introduction, we offer an historical overview of the variety of theories and approaches to schizophrenia. We also provide an overview of how the authors in this volume attempt an integrative account where training, practice, theory and research are considered as parts of a larger whole. This is a varied and pluralistic volume, and it is up to the readers to make use of different chapters according to their own needs. (shrink)

This book explores the relationship between schizophrenia and common sense. It approaches this theme from a multidisciplinary perspective. Coverage features contributions from phenomenology, cognitive neuroscience, philosophy of mind, psychology, and social cognition. -/- The contributors address the following questions: How relevant is the loss of common sense in schizophrenia? How can the study of schizophrenia contribute to the study of common sense? How to understand and explain this loss of common sense? -/- They also consider: What is the relationship of (...) practical reasoning and logical formal reasoning with schizophrenia? What is the relationship between the person with a diagnosis of schizophrenia and social values? -/- Chapters examine such issues as rationality, emotions, self, and delusion. In addition, one looks at brain structure and neurotransmission. Others explore phenomenological and Wittgensteinian theories. The book features papers from the Schizophrenia and Common Sense International Workshop, held at New University of Lisbon, November 2015. It offers new insights into this topic and will appeal to researchers, students, as well as interested general readers. (shrink)