Motor training to improve walking and balance function is a common aspect of rehabilitation following motor-incomplete spinal cord injury. Evidence suggests that moderate- to high-intensity exercise facilitates neuroplastic mechanisms that support motor skill acquisition and learning. Furthermore, enhancing corticospinal drive via transcranial direct current stimulation may augment the effects of motor training. In this pilot study, we investigated whether a brief moderate-intensity locomotor-related motor skill training circuit, with and without tDCS, improved walking and balance outcomes in persons with MISCI. In (...) addition, we examined potential differences between within-day and between-day effects of MST. Twenty-six adults with chronic MISCI, who had some walking ability, were enrolled in a 5-day double-blind, randomized study with a 3-day intervention period. Participants were assigned to an intensive locomotor MST circuit and concurrent application of either sham tDCS or active tDCS. The primary outcome was overground walking speed measured during the 10-meter walk test. Secondary outcomes included spatiotemporal gait characteristics, peak trailing limb angle, intralimb coordination, the Berg Balance Scale, and the Falls Efficacy Scale-International questionnaire. Analyses revealed a significant effect of the MST circuit, with improvements in walking speed, cadence, bilateral stride length, stronger limb TLA, weaker limb ACC, BBS, and FES-I observed in both the MST+tDCSsham and MST+tDCS groups. No differences in outcomes were observed between groups. Between-day change accounted for a greater percentage of the overall change in walking outcomes. In persons with MISCI, brief intensive MST involving a circuit of ballistic, cyclic locomotor-related skill activities improved walking outcomes, and selected strength and balance outcomes; however, concurrent application of tDCS did not further enhance the effects of MST.Clinical Trial Registration[ClinicalTrials.gov], identifier [NCT03237234]. (shrink)

Compassion is a prosocial motivation that is critical to the development and survival of the human species. Cultivating compassion involves developing deep wisdom, insight, and understanding into the nature and causes of human suffering; and wisdom and commitment to take positive action to alleviate suffering. This perspective piece discusses how compassion relates to the context of modern technology, which has developed at a rapid pace in recent decades. While advances in digital technology build on humankind’s vast capacity to develop practical (...) tools that promise to enrich our lives and improve our social connections, in reality the effects are often far from benign. The motives underlying the development of many contemporary digital platforms seem rooted in competitiveness and capitalism; while modern social media and online platforms are having a profound and pervasive impact on the mental health and wellbeing of humans around the globe. Nonetheless, digital technology holds considerable potential to promote compassionate insight, wisdom, and prosocial behavior. We reflect on the current state of technology within human society and examine the notion of compassionate technologies; discuss how contemporary paradigm shifts such as the inclusive design movement may be harnessed to build tools and platforms that promote collective good and increase prosocial behavior; and highlight examples of initiatives that are harnessing modern technology to advance democracy, collective knowledge, and personal freedoms and agency. (shrink)

"The greatest crisis of our times in a failure of the human imagination." -Editors The world is currently undergoing a period of unprecedented crises on virtually every front: economic, ecological, and humanitarian. It is starkly apparent that a shift is needed in our dominant structural systems - and that by addressing the collective thinking that has created and maintained these systems, scholars can do their part to catalyze such a shift. The interdisciplinary field known as the Anthropology of Consciousness (...) offers important insights for enacting this necessary shift. This book draws on the work of a group of diverse scholars to explore what the intersection of anthropology and consciousness studies can contribute to the "public turn" within anthropology and the academy in general. Its twelve chapters span disparate geographies and disciplinary frameworks, yet cohere in their focus on common themes such as imagination, empathy, agency, dialogue, and ethics. The answers to the question "So What? Now What?" differ for a linguistic anthropologist in the South Pacific, an environmental educator in Hawai'i, a grant-writing anthropologist serving a refugee agency in Portland, Oregon and the founder of a girls' school in Brazil. Nevertheless, they are united in the desire to reframe the anthropology of consciousness as an "anthropology of conscience," and this pioneering volume is the result. (shrink)

The potential to instrumentalize drug use based upon the detection of very many different drug states undoubtedly exists, and such states may play a role in psychiatric and many other drug uses. Nevertheless, nonaddictive drug use is potentially more parsimoniously explained in terms of sensation seeking/impulsivity and drug expectations. Cultural factors also play a major role in nonaddictive drug use.

Two experiments are described that investigate the effects of attention in moderating evaluative conditioning (EC) effects in a picture‐picture paradigm in which previously discovered experimental artifacts (e.g., Field & Davey, 1999 Field, AP, and Davey, GCL, (1999). Reevaluating evaluative conditioning: A nonassociative explanation of conditioning effects in the visual evaluative conditioning paradigm, Journal of Experimental Psychology. Animal Behavior Processes 25 ((1999)), pp. 211–224.[Crossref], [PubMed], [Web of Science ®], [Google Scholar]) were overcome by counterbalancing conditioned stimuli (CSs) and unconditioned (...) stimuli (USs) across participants. Conditioned responses for individuals who had attention enhanced were compared against a control group and groups for whom attention was impeded using a distracter task. In a second experiment the effects of attention were dissociated from those of contingency awareness by using backward‐masked US presentations. The results of these experiments indicate that although associative EC effects may not be disrupted by a lack of contingency awareness, attention is an important factor in establishing conditioning. These results shed some light onto the possible boundary conditions that could explain past inconsistencies in obtaining EC effects in the visual paradigm. (shrink)

It is really impossible to say anything worth saying about Plato in general within the limits of a single article. Indeed, the more one studies Plato the more impossible does it become—if the concept of degrees of impossibility may be used in a philosophical journal. The reasons for this are manifold. The first lies in the supreme greatness of Plato as a thinker. Hardly anyone who has made a serious effort to study Plato has escaped receiving the impression of him (...) as probably the greatest thinker of all ages. The difficulty is intensified by the particular form in which his greatness is conveyed to us. One may make a distinction, a relative distinction at least, between different philosophers in this respect. With some, their message is conveyed to us with comparative rapidity, even perhaps on the first careful reading, and subsequent study adds little except in the way of detail. Among these it would perhaps not be unfair to place Hume. Others, on first reading, will appear obscure and difficult, sometimes even repellent. It is only after a much more careful study that their real greatness emerges, and they may go on increasing in stature at every subsequent reading. Such, I believe, to be the experience of the majority of readers with Kant. Plato is almost unique in that he makes his impression in both ways. Almost everyone is captivated by him at first reading, but it is only to those who take the trouble of reading him again and again with the intellectual effort that he himself would have demanded. (shrink)

Is there really such a thing as moral progress? Do we get any better as time goes on? It is a question which must often exercise the minds of those who reflect on moral questions at all. And it is a frequent topic of discussion, both in private conversations and in the written contributions of a good many of our popular philosophers. Of some of these contributions one may safely say that their chief value is as a warning against the (...) dangers of hasty generalization on a subject such as this. And, taking advantage of such a warning, I shall make no attempt to give a final or dogmatic answer to this question. All I can try to do, within the limits of a single lecture, is to disentangle some of the most important considerations that seem to be in people's minds in discussing this question, and to estimate their importance as arguments on one side or the other. (shrink)

Time was when the proofs of the existence of God formed an essential part of any self-respecting system of Philosophy. But for many years now this has ceased to be the case. It may be due to the gradual increase of the influence of Kant that the idea seems to have become accepted, tacitly, in the main, but none the less very widely, that proof or disproof of a belief such as this was hardly a fit subject for philosophical discussion (...) at all. At any rate, it is noteworthy how rarely the question is faced directly in the philosophical discussions of the last forty years or so. What we have had, much more frequently, is discussion about how the God of religion might be thought of and what sort of place He might have in reality as conceived in this or that philosophical system. And certainly discussions on these lines have done much to clarify our conception of the Divine, even if they have sometimes seemed to explain it only by explaining it away altogether, or at any rate to present us with the idea of something which, whatever it is, is certainly not the God of any religion. But of recent years I seem to detect a growing readiness to face the question as squarely as the old theologians, whopropounded the first proofs of God's existence, did. (shrink)

As the HIV epidemic continues to grow worldwide, women are increasingly and disproportionally affected. With the introduction of anti-retroviral medications that have been found to effectively prevent perinatal transmission of HIV, the approach to HIV testing in pregnant women has grown increasingly more controversial. In recent years, the model of voluntary counseling and testing (VCT) has come into question with opt-out testing now advocated for by the Centers for Disease Control and occurring widely in pregnancy. The benefits of opt-out testing (...) are numerous and may justify its use in replacing the VCT that many have come to see as insufficient. An ethical analysis of opt-out testing suggests it may be at odds with true informed consent and involve a degree of coercion that would not be allowed outside the prenatal setting. If opt-out testing is going to remain the standard of care then the ethical issues it raises must be made transparent. Strategies need to be designed for ensuring that HIV counseling and testing in pregnancy is done in accordance with ethical and reproductive rights principles. (shrink)

The object of this paper is, as the title implies, to investigate the relation of Plato’s thought to natural science. More especially, it is intended to examine the widely held view that Plato’s influence, owing to the character of his beliefs, was necessarily and positively unfavourable to the development of natural science, as we know it at the present day.

To anyone who has been engaged in teaching and studying Plato, particularly the Republic , for the last thirty or forty years, one fact must stand out with special prominence. That is the remarkable increase during that period of the direct applicability of Plato's discussions to our own problems. Thirty-five years ago the concrete situations which Plato had in mind in these discussions, the general assumptions at the back of them, the possibilities for good or evil that he envisaged, would (...) all seem to the student of that time remote and almost unreal, and it required a considerable exercise of the imagination to discover that there were certain underlying ideas in them which had application to our own time. If we wanted contemporary illustrations of the rise of a tyrant we had to turn to some of the most backward States in South America. The idea of a completely planned society existed only in the minds of the writers of Utopias, to whom we were accustomed, sometimes, to say rather patronizingly that they had forgotten that constitutions, grow and are not made. We could study the criticisms of democracy as an intellectual exercise without any feeling that they might be one day applied in practice. How different is the situation now! Many of the possibilities are as near for us as they were to Plato. Many of the general ideas of Plato's day are as readily assumed by us as they were by him. Indeed the difficulty now is greater in trying to gain a sympathetic hearing for the ideas of thirty or forty years ago than for the ideas of the fourth century b.c. (shrink)

Whatthe influences were which led to the development and formulation of the so-called Theory of Ideas, usually associated with the name of Plato, is a question of perennial interest. And the interest has been increased by the vigorous controversy that, during the last ten years, has been conducted round the question of the exact part played by Socrates in the development of this theory. All the available evidence on the question is accessible and familiar to students of Greek thought, and (...) has been worked over many times. But as there is still no unanimity among scholars as to its true interpretation, it may be worth while to go over the ground once more, even if the only result is to confirm some view which has already been put forward and disputed. (shrink)

It is really impossible to say anything worth saying about Plato in general within the limits of a single article. Indeed, the more one studies Plato the more impossible does it become—if the concept of degrees of impossibility may be used in a philosophical journal. The reasons for this are manifold. The first lies in the supreme greatness of Plato as a thinker. Hardly anyone who has made a serious effort to study Plato has escaped receiving the impression of him (...) as probably the greatest thinker of all ages. The difficulty is intensified by the particular form in which his greatness is conveyed to us. One may make a distinction, a relative distinction at least, between different philosophers in this respect. With some, their message is conveyed to us with comparative rapidity, even perhaps on the first careful reading, and subsequent study adds little except in the way of detail. Among these it would perhaps not be unfair to place Hume. Others, on first reading, will appear obscure and difficult, sometimes even repellent. It is only after a much more careful study that their real greatness emerges, and they may go on increasing in stature at every subsequent reading. Such, I believe, to be the experience of the majority of readers with Kant. Plato is almost unique in that he makes his impression in both ways. Almost everyone is captivated by him at first reading, but it is only to those who take the trouble of reading him again and again with the intellectual effort that he himself would have demanded. (shrink)