This article investigates the effect of perceived uncertainty on two types of screening strategies – exclusion and inclusion. Results from five studies showed that perceived uncertainty inc...

A personal view made in light of the recent news article regarding a husband wanting to sue Addenbrooke's hospital over a Do Not Attempt Resuscitation decision. This article aims to highlight how the rolling out of cross boundary palliative care registers may be more at risk of infringing human rights.

This personal view draws attention to the lack of regard, given by the BMA in its new guidance, to the symptomatic benefit of clinically assisted nutrition and hydration in patients who are not imminently dying. This article aims to identify how ignoring symptomatic benefit is a serious oversight and cause for concern given that this document, endorsed by the General Medical Council and courts, is created with the purpose of providing a framework for best interests decision-making. The new BMA guidance (...) on CANH, which is endorsed by the GMC,1 follows up on the Supreme Court case of An NHS Trust v Y,2 that any removal of CANH from a patient in prolonged disorder of consciousness no longer requires the approval of the court unless there is disagreement or the decision is finely balanced. The decision in …. (shrink)

A generator program for a computable function (by definition) generates an infinite sequence of programs all but finitely many of which compute that function. Machine learning of generator programs for computable functions is studied. To motivate these studies partially, it is shown that, in some cases, interesting global properties for computable functions can be proved from suitable generator programs which cannot be proved from any ordinary programs for them. The power (for variants of various learning criteria from the literature) of (...) learning generator programs is compared with the power of learning ordinary programs. The learning power in these cases is also compared to that of learning limiting programs, i.e., programs allowed finitely many mind changes about their correct outputs. (shrink)

The advent of techniques of sex selection that rely on assisted reproduction led to a questioning of whether sex selection should be deemed always and everywhere unethical. While China and India are normally associated with condemned practices, they are also implicated in processes that constitute globally stratified sex selection inclusive of its more valued form, often referred to as family balancing. Through an application of Ong and Collier’s concept of global assemblage, I demonstrate how family balancing, which has taken on (...) a “global form,” is tied to an “assemblage” of factors related to the anti-natal, population control contexts that have been pervasive in Asia. Three simultaneously occurring processes since the mid-1990s constituted stratified sex selection: the surfacing of China and India as figurative counter examples in deliberations of ethics on new techniques; active national surveillance of sex ratios as well as denunciation and criminalization of sex selective abortion in China and India; and the role of China and India in neoliberalizing population control and developing globalized markets in reproduction. Accounting for globally stratified sex selection requires a more robust interpretation of ethics that rethinks disciplinary approaches just as much as relativist ones in which respect for individual autonomy tends to overtake all other concerns. (shrink)

In today’s competitive environments, a growing number of firms are establishing their presence through the Web sites. Based on Steuer’s and Rheingold’s arguments on perceptual experience in the virtual space, this paper provides a theoretical framework that highlights the effects of interactivity, immersion, and association for customers. The paper argues that though interactivity, immersion, and association are critical for attracting customers on a Web site, these characteristics may also lead to social, ethical and privacy concerns among customers that many unscrupulous (...) firms tend to exploit for their advantages. Interactivity has been measured through speed, range, and significance of interactivity. Immersion has been measured through breadth and depth of immersion. Association has been categorized into one‐to‐one or many‐to‐many relationships. Four Web sites, amazon.com, eBay.com, schwab.com, and victoriasecret.com, are analyzed with respect to interactivity, immersion, and association. The implications of the use and abuse of interactivity, immersion, and association are discussed. (shrink)

Festschrift in honor of 60th birtha anniversary of Ganesh Umakant Thite, Sanskritist; comprises contributed articles on various aspects of Vedic literature, Hinduism and Indic philosophy.

This paper uses autocatalytic networks to model discontinuous cultural transitions involving cross-domain transfer, using as an illustrative example, artworks inspired by the oldest-known uncontested example of figurative art: the carving of the Hohlenstein-Stadel Löwenmensch, or lion-human. Autocatalytic networks provide a general modeling setting in which nodes are not just passive transmitters of activation; they actively galvanize, or “catalyze” the synthesis of novel nodes from existing ones This makes them uniquely suited to model how new structure grows out of earlier structure, (...) i.e., cumulative, generative network growth. They have been used to model the origin and early evolution of biological life, and the emergence of cognitive structures capable of undergoing cultural evolution. We conducted a study in which six individual creators and one group generated music, prose, poetry, and visual art inspired by the Hohlenstein-Stadel Löwenmensch, and answered questions about the process. The data revealed four through-lines by which they expressed the Löwenmensch in an alternative art form: lion-human hybrid, subtracting from the whole to reveal the form within, deterioration, and waiting to be found with a story to tell. Autocatalytic networks were used to model how these four spontaneously derived through-lines form a cultural lineage from Löwenmensch to artist to audience. We used the resulting data from three creators to model the cross-domain transfer from inspirational source to creative product. These four spontaneously-generated threads of cultural continuity formed the backbone of this Löwenmensch-inspired cultural lineage, enabling culture to evolve even in the face of discontinuity at the level conventional categories or domains. We know of no other theory of cultural evolution that accommodates cross-domain transfer or other forms of discontinuity. The approach paves the way for a broad scientific framework for the origins of evolutionary processes. (shrink)

This paper deals with issues related to character building and human values, both in personal and work life. The focus of the author is value-centred management, which has been discussed along two aspects of the human self, that is, the micro self and macro self. Here, the author tries to highlight the importance of both 'selves' in the organizational context. In the concluding part of the paper the author presents the authenticity of Kautilya's views on the macro self in the (...) context of the present business scenario. The author attempts to portray the transition created by the market economy, which cannot provide an exclusively painless solution. Moreover, he advocates culturing of self-discipline in corporate life, which can bring about qualitative improvement, both in work and personal life. 'Work with integrity and serve with love' is the philosophy the author presents in this paper. (shrink)

In this article, I examine reproductive travel for sex selection with reference to two distinct technologies—MicroSort and preimplantation genetic diagnosis. Available since the 1990s for sex-linked disease avoidance, I focus here on their imbrication in an emerging global form of nonmedical, lifestyle sex selection that elicits movements of information, biomaterial, patients, providers, and equipment across borders. This web of cross-border, interclinical, and laboratory transactions raises issues highly relevant to a feminist approach to the bioethics of sex selection. International documents, however, (...) have yet to account for their implication in an increasingly stratified system of global sex selection practices. (shrink)

The commercialization of egg freezing for fertility preservation spawned a market in information and education as much as in clinical services. Even before there was a technically viable mode to freeze eggs, Christy Jones envisioned “educational seminars” as a key “marketing and education” programmatic strategy in her 2004 contest-winning business plan for an egg freezing company at Harvard Business School. A decade and a half after Jones first proposed them, in-person informational events have become an industry trend. Given the transparent (...) objective of recruiting paying clients, these events must inevitably combine persuasion with education. Through participant observation at three such information sessions held by different clinics in a large city in the eastern US, I present an analysis of their content and form. The article examines the extent to which these events adhered to guidelines on securing informed consent and how the form of these events produce a complex blend of affect and sociality that likely affect how information is received. I argue that egg freezing informational events employ subtle techniques of persuasion that cultivate anxiety and link egg freezing to desirable traits or lifestyles through social enactment. (shrink)

This book presents the historical account of its teachers. To make the reading easy and intelligible its technical terms are explained. The book also explains how PRATYABHIJNA system was formulated and developed by the great teachers.

In 2012, two major professional societies representing Europe and the United States released influential statements that would propel a commercial market for social egg freezing, in which women bank their oocytes for later use in order to avoid compromised fertility that comes with age. While the European Society of Human Reproduction and Embryology condoned SEF based on reproductive autonomy and justice, the American Society for Reproductive Medicine discouraged SEF based on insufficient data and concerns about false hope. In this article, (...) we map the contexts and discursive moves by which the biomedicalization of SEF proceeded since 2012. We compare professional bioethical arguments that made the case to approve SEF in Europe with news and popular media discourse that formed and shaped the commercial marketization of SEF in the United States despite the recommendation of the ASRM. While a statist pronatalist perspective informed the former, a distinctly private labor market recruitment strategy utilizing a Lean In efficiency model of feminism buttressed the latter. (shrink)

The basic premise of this paper originates from the contention that the hegemony of the West is unsustainable because of its grounding on a way of life and life vision not in conformity with the eternal laws of Mother Nature. It is losing its sheen under the impact of unsustainable lifestyle and consumerist culture and the resultant ecological hazards, violence, wars, racial animosity, and religion-induced extremism. These trends are giving way to the emergence of a new humane civilization, and the (...) new civilization shall evolve out of the wisdom accumulated over the past several centuries of human efforts to achieve prosperity and happiness. It should be inclusive and should respect all cultures by providing appropriate space to grow and develop in conformity with the laws of Mother Nature. Santhigiri movement grounded on the revelatory spirituality of Navajyothisree Karunakara Guru offers hope for ushering in of a humane civilization ensuring solidarity beyond religion, race, caste, and region. The view that the academic hegemony of the West has been stifling the voices of varied cultural and religious traditions in other parts of the world and denying due space in the mainstream is examined in the larger context of the unalterable law of cyclical view of history. A historical examination of the hitherto civilizations shows that they have grown in particular directions in parts instead of the whole. A civilization on achieving maximum efficiency in particular directions starts decaying and disintegrating giving way to the shifting of creativity, power, and wealth to another region or continent. This shifting of power, creativity, and wealth from one place to another, one civilization to another has been an unavoidable law of human history. A new civilization that will foster the total efficiency of whole segments of humanity instead of maximum efficiency of parts in particular directions alone can offer human sustainability. The rising Santhigiri Parampara exemplifies the possibility to achieve the goal of human harmony based on the living guidance of wisdom of an Atmajnani Guru. If we can shed our biases and feeling of superiority on any counts and realize our limitations and come out of our unsustainable world view structured by modern science, technology, and instrumental rationality and seek the whole, we all can enjoin in this global mission of raising human consciousness into higher levels of attainment which can lead to an egalitarian and enlightened culture. (shrink)

In the model theory of modules the Ziegler spectrum, the space of indecomposable pure-injective modules, has played a key role. We investigate the possibility of defining a similar space in the context of G-sets where G is a group.

Unlike majority of classical and contemporary Indian philosophers, Gandhi was a practical philosopher, an experimentalist and a laboratiorian who developed practical instruments and carried out experiments for the existing life problems without bothering to build a consistent structure of philosophy. For this very reason there seems an ambiguity to call Gandhi as a philosopher. However, it seems to me that Gandhi was a practical philosopher who laid a pragmatic approach and method to his new insights for social and political action (...) of national movement and the reconstruction of modern India without disturbing the social equilibrium.Gandhi exercised such tremendous skill in cooperative participation of our national movement and is rudely regarded as the “Father of pridely Nation”. As he is too skillfully organized his ideals in building a nation he rightfully ascertained as philosopher in the light of Homer’s (the Greek poet) definition to a philosopher. The same practical method is extended to the aspect of religion by Gandhi. (shrink)

Business Ethics, the Environment &Responsibility, EarlyView.

The motivation of someone who is locked-in, that is, paralyzed and mute, is to find relief for their loss of function. The data presented in this report is part of an attempt to restore one of those lost functions, namely, speech. An essential feature of the development of a speech prosthesis is optimal decoding of patterns of recorded neural signals during silent or covert speech, that is, speaking “inside the head” with output that is inaudible due to the paralysis of (...) the articulators. The aim of this paper is to illustrate the importance of both fast and slow single unit firings recorded from an individual with locked-in syndrome and from an intact participant speaking silently. Long duration electrodes were implanted in the motor speech cortex for up to 13 years in the locked-in participant. The data herein provide evidence that slow firing single units are essential for optimal decoding accuracy. Additional evidence indicates that slow firing single units can be conditioned in the locked-in participant 5 years after implantation, further supporting their role in decoding. (shrink)

The role of antibody-antigen affinity and concentrations in adaptive antibody response is analyzed in a framework of probabilistic inventory model for antibody production. Our results indicate significant differences in optimal behaviours of low, moderate and high affinity groups and offer important implications. Interestingly, the involved approach is also of relevance in other production systems. Directions for its applications in industries and information sciences are also presented.