BackgroundHigh frequency repetitive transcranial magnetic stimulation of the left dorsolateral prefrontal cortex has shown significant efficiency in the treatment of resistant depression. However in healthy subjects, the effects of rTMS remain unclear.ObjectiveOur aim was to determine the impact of 10 sessions of rTMS applied to the DLPFC on mood and emotion recognition in healthy subjects.DesignIn a randomised double-blind study, 20 subjects received 10 daily sessions of active or sham rTMS. The TMS coil was positioned on the left DLPFC through neuronavigation. (...) Several dimensions of mood and emotion processing were assessed at baseline and after rTMS with clinical scales, visual analogue scales, and the Ekman 60 faces test.ResultsThe 10 rTMS sessions targeting the DLPFC were well tolerated. No significant difference was found between the active group and the control group for clinical scales and the Ekman 60 faces test. Compared to the control group, the active rTM... (shrink)

The majority of evidence on social anxiety -linked attentional biases to threat comes from research using facial expressions. Emotions are, however, communicated through other channels, such as voice. Despite its importance in the interpretation of social cues, emotional prosody processing in SA has been barely explored. This study investigated whether SA is associated with enhanced processing of task-irrelevant angry prosody. Fifty-three participants with high and low SA performed a dichotic listening task in which pairs of male/female voices were presented, one (...) to each ear, with either the same or different prosody. Participants were instructed to focus on either the left or right ear and to identify the speaker’s gender in the attended side. Our main results show that, once attended, task-irrelevant angry prosody elicits greater interference than does neutral prosody. Surprisingly, high socially anxious participants were less prone to distraction from attended-angry prosody than were low socially anxious individuals. These findings emphasise the importance of examining SA-related biases across modalities. (shrink)

VIRGINIE MARIS,ÉLISE HUCHARD | : Considérant l’ubiquité de la souffrance dans le monde sauvage, la question se pose de notre obligation d’intervenir. Du simple devoir d’assistance dans des situations ponctuelles à des projets de transformation des conditions de vie animale à grande échelle, la défense de l’interventionnisme entre en conflit avec la pensée conservationniste qui valorise la naturalité ou l’autonomie des systèmes écologiques. Dans cet article, nous tentons de mettre en dialogue les intuitions interventionnistes et la pensée conservationniste. Nous (...) exposons tout d’abord l’argument interventionniste et ses limites épistémiques. Nous mitigeons ensuite le constat selon lequel les conditions de vie des animaux sauvages justifient notre intervention en replaçant le problème de la souffrance dans un cadre évolutif et écologique plus large puis en insistant sur d’autres obligations vis-à-vis des animaux sauvages comme le respect de leur autonomie ou de leur souveraineté. Enfin, nous défendons une conception pluraliste de nos relations au monde naturel dans laquelle le souci pour les animaux s’équilibre avec d’autres valeurs écocentrées. Nous concluons en présentant les ressources encore peu explorées d’une conservation compassionnelle qui intègre le souci pour les individus et le souci pour les collectifs écologiques dans les normes de ses actions. | : The ubiquity of suffering in the wild raises the question of our obligation to intervene. From a simple duty of assistance in particular situations to large-scale projects aimed at transforming animal living conditions, the defense of interventionism often conflicts with conservationist values, which emphasize the naturalness or autonomy of ecological systems. In this article, we attempt to open a dialogue between interventionist intuitions and the conservationist school of thought. We first expose the interventionist argument and its epistemic limitations. We subsequently mitigate the statement according to which the living conditions of wild animals justify human intervention by replacing the problem of suffering in a broader ecological and evolutionary framework, as well as by insisting on other obligations that we may have towards wild animals, such as the respect of their autonomy and sovereignty. Finally, we defend a pluralistic conception of our relationships to the natural world, in which care for animals has to be balanced with other, eco-centered, values. We conclude by presenting the resources of a compassionate conservation approach, which remains largely unexplored and integrates care for individual animals as well as for ecological entities in its norm for action. (shrink)

The ventricular pressure profile is characteristic of the cardiac contraction progress and is useful to evaluate the cardiac performance. In this contribution, a tissue-level electromechanical model of the left ventricle is proposed, to assist the interpretation of left ventricular pressure waveforms. The left ventricle has been modeled as an ellipsoid composed of twelve mechano-hydraulic sub-systems. The asynchronous contraction of these twelve myocardial segments has been represented in order to reproduce a realistic pressure profiles. To take into account the different energy (...) domains involved, the tissue-level scale and to facilitate the building of a modular model, multiple formalisms have been used: Bond Graph formalism for the mechano-hydraulic aspects and cellular automata for the electrical activation. An experimental protocol has been defined to acquire ventricular pressure signals from three pigs, with different afterload conditions. Evolutionary Algorithms have been used to identify the model parameters in order to minimize the error between experimental and simulated ventricular pressure signals. Simulation results show that the model is able to reproduce experimental ventricular pressure. In addition, electro-mechanical activation times have been determined in the identification process. For example, the maximum electrical activation time is reached, respectively, 96.5, 139.3 and 131.5 ms for the first, second, and third pigs. These preliminary results are encouraging for the application of the model on non-invasive data like ECG, arterial pressure or myocardial strain. (shrink)

In the twelfth and thirteenth centuries, new ways of storytelling and inventing fictions appeared in the French-speaking areas of Europe. This new art still influences our global culture of fiction. Virginie Greene explores the relationship between fiction and the development of neo-Aristotelian logic during this period through a close examination of seminal literary and philosophical texts by major medieval authors, such as Anselm of Canterbury, Abélard, and Chrétien de Troyes. This study of Old French logical fictions encourages a broader (...) theoretical reflection about fiction as a universal human trait and a defining element of the history of Western philosophy and literature. Additional close readings of classical Greek philosophers Plato and Aristotle, and modern analytic philosophy including the work of Bertrand Russell and Rudolf Carnap, demonstrate peculiar traits of Western rationalism and expose its ambivalent relationship to fiction. (shrink)

This article aims to establish the biography of Ἁbd al-Raḥmān ibn Rustum who founded the Ibāḍī Rustumid dynasty. Ἁbd al-Raḥmān grew up in al-Qayrawān, then he learned in Baṣra with the Ibāḍī scholar Abū ῾Ubayda Muslim ibn Abī Karīma al-Tamīmī. Afterwards he came back to the Maghrib in a group of «bearers of learning». In 140/757–758, he declined the Imāmate offered to him in favour of Abū l-Ḫaṭṭāb al-Ma῾āfirī. The latter took al-Qayrawān and proclaimed Ἁbd al-Raḥmān governor of the city. (...) After the Ἁbbāsid reconquest and Abū l-Ḫaṭṭāb's death in 144/761–762, Ἁbd al-Raḥmān founded Tāhart. He was proclaimed Imām in 160/776–777 or 162/778–779. Under his reign, the Ibāḍī capital developed considerably. (shrink)

En plus de la sécession des nukkārites et des ḫalafites, l’imam rustumide Aflaḥ doit affronter la dissidence de Naffāṯ b. Naṣr. Après s’être vu refuser le poste de gouverneur de Qanṭrāra, Naffāṯ se met à calomnier publiquement Aflaḥ, auquel il reproche principalement ses goûts de luxe et son manque de combativité face aux Aġlabides. La propagande anti-rustumide de Naffāṯ séduit rapidement de nombreux ibadites, tant dans le Djérid qu’au djebel Nafūsa. Cet engouement montre à quel point, pendant le règne d’Aflaḥ (...) déjà, l’autorité rustumide est remise en cause par les populations ibadites. Bien qu’il ne provoque aucun conflit armé, ce schisme suscite de grandes inquiétudes au plus haut niveau de l’État rustumide. Nous avons réuni dans cet article toutes les éléments qui se rapportent à Naffāṯ, afin de tenter de reconstituer sa vie et de dresser la liste des nouvelles idées qu’il a proposées. Le mouvement naffatite est particulièrement intéressant, d’une part par sa longévité et son extension géographique, d’autre part par le grand nombre de documents qui s’y rapportent. Ces documents, apparaissant très progressivement au fil des siècles dans les sources ibadites, permettent de mieux comprendre la personnalité de Naffāṯ b. Naṣr., qui fut davantage un intellectuel que le chef d’un mouvement organisé. (shrink)

Ah ! Nana est un journal de bande dessinée publié entre 1976 et 1978. Adapté d’un magazine apparu aux USA en 1970, le Wimmen’s comix, sa spécificité est d’être réalisé par des femmes et de viser un lectorat féminin. C’est pourquoi il représente une aventure pionnière dans le monde de la bande dessinée française. Son contenu reflète les préoccupations féministes de son temps, pour aborder des sujets les plus délicats comme les plus tabous de la société de la fin des (...) années 1970, parmi lesquels la sexualité féminine, l’inceste ou les différentes violences subies par les femmes. Des dossiers consacrés à une thématique particulière sont appuyés par une mise en image sans détours, crue et parfois cruelle. Il en faut beaucoup pour bouleverser les mentalités. Les femmes d’Ah ! Nana en ont-elles trop fait ? En tout cas ce projet était trop original pour survivre à cette époque. Il est un échec commercial que le poids de la censure condamne définitivement. Mais il reste une tentative, jusqu’ici jamais reconduite en France, de permettre aux femmes de s’exprimer dans la bande dessinée et il rend compte de leurs difficultés à être publiées. (shrink)

Cet article propose d’examiner la manière dont les pratiques médicales informelles utilisant les cellules humaines ont été réunies en une technologie intégrée sur deux décennies. Dans ce processus, les débats de la bioéthique constituent un dispositif d’épreuves permettant d’unifier ces pratiques disparates sous le label commun de « thérapie cellulaire ». En établissant des articulations possibles entre la production matérielle d’un savoir médical et ses inscriptions institutionnelles, le travail de requalification bioéthique s’effectue suivant trois registres. Tout d’abord, les controverses bioéthiques (...) assignent un label médical à des technologies qui n’existent alors que sous la forme de projet articulé à des pratiques de laboratoire . Ensuite, elles définissent des entités du vivant en objet technique, par exemple en dissociant les cellules souches de l’embryon. Enfin, elles introduisent des catégories distinctes de pratiques à partir d’une même technique. En ce sens, la bioéthique constitue un standard politique, inextricable de l’action publique en matière de biotechnologies. Suivre la construction sociale des objets biologiques conduit à établir un modèle de standardisation des innovations biomédicales et à promouvoir une sociologie pragmatique basée sur la genèse des standards.This article focuses on how informal medical practices using human cells had been joined together in the shape of integrated technology for two decades. The debates of bioethics are part of this constant process ; they intervene as a test plan enabling to qualify these disparate practices to which they relate by the name of cell therapies. By establishing possible links between the material production of medical knowledge and its institutional inscriptions, the work of bioethics re-qualification is carried out according to three levels. First, bioethics controversies assign a medical label to technologies which do not exist except in the form of projects articulated through laboratory practices . Second, they define entities of the living as technical object, for example, by dissociating the stem cells from an embryo. Lastly, they introduce distinct categories of practices coming from the same technical roots. In this sense, bioethics constitutes a political standard, inextricable from public action in biotechnologies. Tracking the social construction of biological objects leads to establish a standardization pattern of biomedical innovations and to promote a pragmatics sociology based on the standards genesis. (shrink)

Le lien mère/fille, ou éducatrice/danseuse, tel qu’il s’exprime au cours de l’apprentissage de la danse classique, est ici discuté à deux époques différentes, le xixe siècle et la période actuelle, à partir de témoignages écrits sur la vie des élèves dans l’Opéra ancien et d’enquêtes orales auprès de danseuses contemporaines. Il en ressort qu’au xixe siècle comme aujourd’hui, mères et éducatrices ne permettent pas à ces jeunes filles d’accéder facilement au statut de femme ; les jeunes danseuses du xixe siècle (...) n’avaient pour certaines pas de liberté dans leur choix matrimonial, devaient pour d’autres subvenir aux besoins de leur famille, tandis qu’aujourd’hui mères et éducatrices les maintiennent dans le statut de « fille ». (shrink)

This paper is based on a research conducted between 2004 and 2006 and dealing with the memories of women in a steel valley struck by depression since the seventies, in the North-Eastern part of France. The imagery of steel-producing Lorraine coalesced in a rather standardized way around the figure of the steelworker working at the blast furnace. This research and the exhibition which followed from it, highlighted the activities of women, in the working place as well as in the domestic (...) realm and in community or political movements. It thus contributes to a more complex imagining and less androcentric perspective on the ironworks past of the Lorraine region. (shrink)

Depuis une vingtaine d’années, un ensemble diversifié de domaines de recherche s’est constitué autour de l’étude et de la fabrication de systèmes artificiels visant à reproduire l’organisation de la vie. Pluridisciplinaire, la vie artificielle est consacrée nouvelle discipline scientifique en 19871. Elle a été définie par Langton comme « l’étude de systèmes construits..

This article aims to explore the attitudes and behaviors of persons with intellectual and developmental disabilities related to their information privacy when using information technology. Six persons with IDD were recruited to participate to a series of 3 semistructured focus groups. Data were analyzed following a hybrid thematic analysis approach. Only 2 participants reported using IT every day. However, they all perceived IT use benefits, such as an increased autonomy. Participants demonstrated awareness of privacy concerns, but not in situations involving (...) the use of technology; their awareness is not transferred to the abstract context of IT use. Privacy breaches were revealed to be a major risk for persons with IDD, who did not seem to understand how their personal information was used. Most protection mechanisms and tools reported were those suggested and implemented by caregivers and close relatives who had a great influence on the participants’ attitudes and behaviors toward IT and privacy. Our findings suggest that when using IT, persons with IDD often experience the consequences of a trade-off between autonomy and privacy. Further research and action is needed to support persons with IDD to understand and balance the benefits of IT use and the inherent threats to information privacy. (shrink)

Dream is a state of consciousness characterized by internally-generated sensory, cognitive and emotional experiences occurring during sleep. Dream reports tend to be particularly abundant, with complex, emotional, and perceptually vivid experiences after awakenings from rapid eye movement sleep. This is why our current knowledge of the cerebral correlates of dreaming, mainly derives from studies of REM sleep. Neuroimaging results show that REM sleep is characterized by a specific pattern of regional brain activity. We demonstrate that this heterogeneous distribution of brain (...) activity during sleep explains many typical features in dreams. Reciprocally, specific dream characteristics suggest the activation of selective brain regions during sleep. Such an integration of neuroimaging data of human sleep, mental imagery, and the content of dreams is critical for current models of dreaming; it also provides neurobiological support for an implication of sleep and dreaming in some important functions such as emotional regulation. (shrink)