One question in moral psychology concerns the role of emotions to motivate moral action. This question has recently become more urgent, because it is now clearer that cognitive developmental theories cannot offer a complete explanation of moral functioning. This paper suggests that emotion, as is typically understood in psychology, cannot be seen as the basis for an acceptable explanation of moral behaviour and motivation. However, it is argued that it is possible to understand emotions as embedded in agentic processes, and (...) regulated by conscious concerns. So understood, emotions acquire an important role in the person's moral life. These conclusions are reached through an extensive review of psychological and philosophical conceptions. (PsycINFO Database Record (c) 2010 APA, all rights reserved). (shrink)

We invoke the ideal of tolerance in response to conflict, but what does it mean to answer conflict with a call for tolerance? Is tolerance a way of resolving conflicts or a means of sustaining them? Does it transform conflicts into productive tensions, or does it perpetuate underlying power relations? To what extent does tolerance hide its involvement with power and act as a form of depoliticization? Wendy Brown and Rainer Forst debate the uses and misuses of tolerance, an exchange (...) that highlights the fundamental differences in their critical practice despite a number of political similarities. Both scholars address the normative premises, limits, and political implications of various conceptions of tolerance. Brown offers a genealogical critique of contemporary discourses on tolerance in Western liberal societies, focusing on their inherent ties to colonialism and imperialism, and Forst reconstructs an intellectual history of tolerance that attempts to redeem its political virtue in democratic societies. Brown and Forst work from different perspectives and traditions, yet they each remain wary of the subjection and abnegation embodied in toleration discourses, among other issues. The result is a dialogue rich in critical and conceptual reflections on power, justice, discourse, rationality, and identity. (shrink)

Does God have any relevant role in the new natural law theory of Germain Grisez and John Finnis? Finnis declared in Natural Law and Natural Rights that he wanted to offer “a theory of natural law without needing to advert to the question of God’s existence or nature or will.” Grisez claims that “man’s ultimate beatitudo cannot consist in the vision of God.” Indeed, there is no consistent role for God in their philosophical theory. In this article, the author shows (...) that their mistakes about God depend first on their metaphysical way of looking at nature, which is closer to thinkers like Hume and Kant than to Aristotle and Aquinas; and second on some strong misunderstandings in moral philosophy about the concept of ultimate end. He shows the unfortunate theological outcome their flawed metaphysics and morality have already produced. National Catholic Bioethics Quarterly 13.1 (Spring 2013): 35–45. (shrink)

We invoke the ideal of tolerance in response to conflict, but what does it mean to answer conflict with a call for tolerance? Is tolerance a way of resolving conflicts or a means of sustaining them? Does it transform conflicts into productive tensions, or does it perpetuate underlying power relations? To what extent does tolerance hide its involvement with power and act as a form of depoliticization? Wendy Brown and Rainer Forst debate the uses and misuses of tolerance, an exchange (...) that highlights the fundamental differences in their critical practice despite a number of political similarities. Both scholars address the normative premises, limits, and political implications of various conceptions of tolerance. Brown offers a genealogical critique of contemporary discourses on tolerance in Western liberal societies, focusing on their inherent ties to colonialism and imperialism, and Forst reconstructs an intellectual history of tolerance that attempts to redeem its political virtue in democratic societies. Brown and Forst work from different perspectives and traditions, yet they each remain wary of the subjection and abnegation embodied in toleration discourses, among other issues. The result is a dialogue rich in critical and conceptual reflections on power, justice, discourse, rationality, and identity. (shrink)

After introducing the new field of cultural evolution, we review a growing body of empirical evidence suggesting that culture shapes what people attend to, perceive and remember as well as how they think, feel and reason. Focusing on perception, spatial navigation, mentalizing, thinking styles, reasoning (epistemic norms) and language, we discuss not only important variation in these domains, but emphasize that most researchers (including philosophers) and research participants are psychologically peculiar within a global and historical context. This rising tide of (...) evidence recommends caution in relying on one’s intuitions or even in generalizing from reliable psychological findings to the species, Homo sapiens. Our evolutionary approach suggests that humans have evolved a suite of reliably developing cognitive abilities that adapt our minds, information-processing abilities and emotions ontogenetically to the diverse culturally-constructed worlds we confront. (shrink)

The aim of this study was to explore the role of voices as cues to adults of children’s needs for potential caregiving during early childhood. To this purpose, 74 college students listened to pairs of 5-year-old versus 10-year-old children verbalizing neutral-content sentences and indicated which voice was better associated with each of 14 traits, potentially meaningful in interactions between young children and adults. Results indicated that children with immature voices were perceived more positively and as being more helpless than children (...) with mature voices. Children’s voices, regardless of the content of speech, seem to be a powerful source of information about children’s need for caregiving for parents and others during the first six years of life. (shrink)

Nietzsche, para Heidegger, não teria levado a termo a desvalorização dos valores considerados até então válidos. A transvalorização, ao invés de garantir a renovação da condição existencial do homem, antepõe, à tematização do ser, o nada mudado em vontade e representação. O querido, contra os pressupostos da vontade de poder, se esclerosa na tangibilidade das coisas sem a possibilidade do além por meio do qual Nietzsche pensava superar o niilismo. A transvaloração conserva em tal aspecto a lógica dos velhos valores (...) por conta de uma vontade fixada na presumida concretude da enticidade. Nietzsche é o paradigma de uma metafísica que pensa o ser dentro da não verdade ou de uma verdade transformada na relação sujeitoobjeto. Por tudo isso, a transvaloração, longe de fundar uma nova posição de valores, é adscrivível à nadificação do sujeito, constantemente correlacionado ao objeto. O super-homem não é senão uma super-objetividade que se ilude de reviver na mais completa plenitude, com base no platonismo invertido. Contra Nietzsche, os niilismos se assemelham por não poderem não pensar o ser ao modo de um ser-aí: uma paranoica divinização da corporeidade dentro da realidade mundana. Palavras-chave: Nietzsche. Heidegger. Kant. Transvaloração. Metafísica. Niilismo. (shrink)

Contemporary studies in unconscious cognition are essentially founded on dissociation, i.e., on how it dissociates with respect to conscious mental processes and representations. This is claimed to be in so many and diverse ways that one is often lost in dissociation. In order to reduce this state of confusion we here carry out two major tasks: based on the central distinction between cognitive processes and representations, we identify and isolate the main dissociation paradigms; we then critically analyze their key tenets (...) and reported findings. (shrink)

Since Freud and his co-author Breuer spoke of dissociation in 1895, a scientific paradigm was painstakingly established in the field of unconscious cognition. This is the dissociation paradigm. However, recent critical analysis of the many and various reported dissociations reveals their blurred, or unveridical, character. Moreover, we remain ignorant with respect to the ways cognitive phenomena transition from consciousness to an unconscious mode. This hinders us from filling in the puzzle of the unified mind. We conclude that we have reached (...) a Kuhnian crisis in the field of unconscious cognition, and we predict that new models, incorporating partly the relevant findings of the dissociation paradigm—but also of dynamic psychology—, will soon be established. We further predict that some of these models will be largely based on the pairs representation–process and analog–digital. (shrink)

Este artículo trata sobre la postura práctica de Aquino ante dos grandes dificultades filosóficas actuales que se encuentran en la base del debate ético contemporáneo. Como son la Is-ought thesis de Hume y la síntesis radical de Moore, la Open question. La posible solución tomista se puede encontrar en la triple función del intelecto humano, teórico y práctico a la vez: a) Aprehender las nociones ontológicas e intelectas ens, verum y bonum; b) Formular los primeros principios teóricos y prácticos; c) (...) E imperar que se haga el bien ontológico e intelecto y se evite lo contrario. (shrink)

Urokinase and its receptor are essential components of the cell migration machinery, providing an inducible, transient and localized cell surface proteolytic activity. This activity has been shown to be required in normal and pathological forms of cellular invasiveness (i.e. in several embryonic developmental processes, during inflammatory responses and cancer metastasis and spreading). It represents one of the best known of the protcolytic systems which are currently under investigation in this field. The urokinase receptor allows a continuous regulation of the proteolytic (...) activity at cell contacts, utilizing the different localization of urokinase and its inhibitors. The receptor, in fact, in addition to focusing the enzymatic activity at focal and cell‐cell contacts, also regulates it by internalizing and degrading only the inhibited form of urokinase. Internalized receptor releases the ligands to the lysosomes and recycles back to surface. In this way, the proteolytically active areas of the cell surface can be continuously monitored for their activity and their location modified. The cell can thus coordinate its migration efforts with a step‐wise modification of the proteolytic activity‐map of the cell surface. The urokinase cycle can be supported by one individual cell (autocrine) or by two or more cells. In the latter case, complementation and synergism of urokinase and its receptor are found. (shrink)

Le stanze del canto. La musica e l'indicibile ; Il linguaggio degli angeli ; Musica e utopia ; Musica e prassi analitica ; Un sogno musicale -- Variazioni sul tema. Musica, mistero e mondo femminile in E.T.A. Hoffmann ; Thomas Bernhard e l'estetica del narcisismo ; I tragitti di Orfeo -- Coda : Dialogo di Eusebio e Florestano -- Appendice : La principessa nascosta : psicoterapia e fare poetico.

This article concerns Aquinas’s practical doctrine on two philosophical difficulties underlying much contemporary ethical debate. One is Hume’s Is-ought thesis and the other is its radical consequence, Moore’s Open-question argument. These ethical paradoxes appear to have their roots in epistemological scepticism and in a deficient anthropology. Possible response to them can be found in that Aquinas’s human intellect (essentially theoretical and practical at the same time) naturally performs three main operations: 1º) To apprehend the intellecta and universal notions ens, verum (...) and bonum. 2º) To formulate the first theoretical and practical principles. 3º) To order that the intellectum and universal good be done and the opposite avoided. Thomistic philosophical response to both predicaments will not be exclusively ethical, but will harmonically embrace ontology, anthropology and epistemology. (shrink)

O trabalho pretende, a partir da publicação das “Confissões da Carne”, analisar o impasse que diz respeito a sua não publicação em vida por Foucault, em especial em função da entrada do sujeito como terceiro componente do triângulo arqueológico-genealógico, impondo uma reviravolta decisiva em sua pesquisa. A força aletúrgica do sujeito implica uma definitiva dessoberanização do dispositivo de poder. Por um lado, se a forma moderna prevê a sua transferência de um poder sobre si próprio aos outros, o complexo de (...) estratégias governamentais, que «orientam» a direção da consciência, não implica a abdicação da liberdade por parte da pessoa a qual foi dirigida; por outro, uma segunda operação surge da diferenciação específica entre o modelo antigo e o modelo cristão, quer dizer, se o antigo modelo de direção funciona com vistas à autonomização do sujeito, aquele exame de consciência cristão estabelece como eixo a dependência e desenvolve uma racionalidade pastoral. Assim Foucault chega a uma estética da existência que é puro exercício de liberdade e perfeita atitude, que se oferece aos outros como prova do seu próprio valor. É com isso que o volume quarto da história da sexualidade é confrontado. O que muda drasticamente na experiência cristã da carne é a relação do sujeito com a verdade. A confissão, mais do que expiação dos pecados, neste quadro intervém como atestado e como testemunho de si próprio. Em conclusão, para Foucault, conotado pela imperfeição que o domina, o sujeito cristão liga-se a uma interminável direção de consciência cujo preço é uma perda de identidade indefinida. Assim, a partir deste recorte, o problema que passa a enfrentar é como encontrar uma forma de fundamentar a hermenêutica de si, não no sacrifício, mas numa “emergência positiva”, teórica e prática, de si, expondo tanto o momento transicional das “Confissões da Carne” quanto a própria razão pela qual renuncia à sua publicação. (shrink)

Este livro é o resultado de um estudo sobre a teoria da montagem cinematográfica.

We report the latest structural information on PREP1 tumor suppressor, the specific “oncogene” and “tumor suppressive” signatures of MEIS1 and PREP1, the molecular rules regulating PREP1 and MEIS1 binding to DNA, and how these can change depending on the interaction with PBX1, cell‐type, neoplastic transformation, and intracellular concentration. As both PREP1 and MEIS1 interact with PBX1 they functionally compete with each other. PREP1, PBX1, and MEIS1 TALE‐class homeodomain transcription factors act in an interdependent and integrated way in experimental tumorigenesis. We (...) also pool together the plethora of data available in human cancer databanks and connect them with the available molecular information. The emerging picture suggests that a similarly basic approach might be used to better dissect and define other oncogenes and suppressors and better understand human cancer. (shrink)

The representational nature of human cognition and thought in general has been a source of controversies. This is particularly so in the context of studies of unconscious cognition, in which representations tend to be ontologically and structurally segregated with regard to their conscious status. However, it appears evolutionarily and developmentally unwarranted to posit such segregations, as,otherwise, artifact structures and ontologies must be concocted to explain them from the viewpoint of the human cognitive architecture. Here, from a by-and-large Classical cognitivist viewpoint, (...) I show why this segregation is wrong, and elaborate on the need to postulate an ontological and structural continuity between unconscious and conscious representations. Specifically, I hypothesize that this continuity is to be found in the symbolic-based interplay between the syntax and the semantics of thought, and I propose a model of human information processing characterized by the integration of syntactic and semantic representations. (shrink)

O presente estudo tem como tema o surveillance e a sociedade do controle biopolítico, sendo dada ênfase à conexão com o sistema penal e as tecnologias dispostas nas práticas de segurança. Tem-se como problema de pesquisa como e de que forma operam os “novos” mecanismos de surveillance em prol da segurança no modelo biopolítico do Estado penal? Conclui-se que o modelo de controle atual baseado em riscos e algoritmos emprega o surveillance em uma atuação securitária seletiva, adotando o discurso “científico/tecnológico” (...) como escusa para manutenção discriminatória de uma biopolítica da atuação penal voltada para morte de sujeitos e grupos sociais específicos. Por fim, a metodologia empregada compreende uma abordagem fenomenológico-hermenêutica, um método de procedimento monográfico e técnica de pesquisa por documentação indireta. (shrink)

The traditional model of human cognition (TMHC) postulates an ontological and/or structural gap between conscious and unconscious mental representations. By and large, it sees higher-level mental processes as commonly conceptual or symbolic in nature and therefore conscious, whereas unconscious, lower-level representations are conceived as non-conceptual or sub-symbolic. However, experimental evidence belies this model, suggesting that higher-level mental processes can be, and often are, carried out in a wholly unconscious way and/or without conceptual representations, and that these can be processed unconsciously. (...) This entails that the TMHC, as well as the theories on mental representation it motivates and that in turn support it, is wrong. (shrink)

El artículo pretende discutir, a la luz del debate contemporáneo entremoralidad y eticidad, los modelos de comportamiento moral en el Perú. Lacrítica a la moralidad (moral moderna) se desarrolla contrastando los ideales y la práctica de los liberales independentistas del S. XIX. A pesar deexistir una mezcla de contenidos morales, las alternativas que se buscanposteriormente implican un retorno a la moral aristotélica y cristiana ( eticidad). Esto es lo que se observa en filósofos como Alejandro Deustua, en políticos como Víctor (...) Andrés Belaunde y José Carlos Mariátegui, y particularmente en la narrativa de José María Arguedas. (shrink)

Given the evidence available today, we know that the later Middle Ages knew strong forms of idealism. However, Plato alone will not do to explain some of its features. Aristotle was the most important philosophical authority in the thirteenth and fourteenth centuries, but until now no one dared explore in his thought the roots of this idealism because of the dogma of realism surrounding him. I challenge this dogma, showing that the Stagirite contained in his thought the roots of idealist (...) aspects that will be developed, namely by Dietrich of Freiberg and Eckhart of Hochheim, into a fully idealist epistemology. (shrink)

Foundational ontologies, central constructs in ontological investigations and engineering alike, are based on ontological categories. Firstly proposed by Aristotle as the very ur- elements from which the whole of reality can be derived, they are not easy to identify, let alone partition and/or hierarchize; in particular, the question of their number poses serious challenges. The late medieval philosopher Dietrich of Freiberg wrote around 1286 a tutorial that can help us today with this exceedingly difficult task. In this paper, I discuss (...) ontological categories and their importance for foundational ontologies from both the contemporary perspective and the original Aristotelian viewpoint, I provide the translation from the Latin into English of Dietrich's De origine II with an introductory elaboration, and I extract a foundational ontology–that is in fact a single-category one–from this text rooted in Dietrich's specification of types of subjecthood and his conception of intentionality as causal operation. (shrink)

Ontologies are some of the most central constructs in today's large plethora of knowledge technologies, namely in the context of the semantic web. As their coinage indicates, they are direct heirs to the ontological investigations in the long Western philosophical tradition, but it is not easy to make bridges between them. Contemporary ontological commitments often take causality as a central aspect for the ur-segregation of entities, especially in scientific upper ontologies; theories of causality and philosophical ontological investigations often go hand-in-hand, (...) and were essentially inseparable in medieval thought. This constitutes the foundation for a bridge, and this article analyzes the causality-based ontology of the late medieval philosopher Dietrich of Freiberg from the viewpoint of today's upper-ontology engineering. In this bridging attempt, it offers a translation into English of the first part of Dietrich's De origine (abbreviated title) that is a compromise between traditional scholarly translations of medieval Latin philosophical texts and contemporary ontology. (shrink)