In 1948 the pharmaceutical company Leo launched a placental hormonal preparation, called Gonadex, in Sweden. During a press conference, and in commercials and newspapers, it was said that Gonadex could cure sterility as well as many other problems related to the endocrine system. The remedy was described as effective and pure, with no side effects whatsoever. For several reasons, Gonadex was looked upon as a ‘Swedish triumph’. Inspired by research on ‘mediation’, conducted within the field of social studies of pharmaceutical (...) drugs, the present essay explores the political and scientific visions and values behind Gonadex; the propaganda for and marketing of Gonadex; the mediated image of Gonadex in the press; the reception by the medical profession, and finally the hopes and fears of the women who tried Gonadex. The essay argues that the public image of Gonadex was ‘oversell’ of hormone therapy, and that it was shaped by the way endocrinologists at Karolinska Hospital, notably Professor Axel Westman, mediated between Leo, the mass media, and the consumers when, and even before, Gonadex was introduced to the market. (shrink)

The subject matter of this thesis is analytic ontology. Chapters II and III deal with two versions of trope theory, or moderate nominalism; these are defined as ontologies which recognise properties and relations but no (real) universals. The key notion of both theories, trope, is characterised as an abstract particular. What the abstractness amounts to differs between the two. Yet another difference is that simplicity is an essential trait of a trope according to one theory, but not according to the (...) other. Though exact similarity is said to play an important role in both theories, as it turns out, this does not seem to be the case. The ontology dealt with in chapter IV is a mixture of moderate nominalism concerning qualities and realism concerning relations. In it, quality instances (moments) and universal relations are the ultimate constituents of the universe. While relations and moments are considered to be constituents of states of affairs, which are characterised as objects of higher orders, complexes that are objects of the first order are made up of moments on their own. Among these complexes one finds the ordinary objects. Paradoxically, although relations are necessary for the existence of complex first order objects, relations are not thought to be among the contents of these objects. The main subject of chapter V is a particular version of moderate realism; it is an ontology which is realistic in its recognition of universals and moderate in its recognition of instances of these universals. Instances combine to form complex networks. A theoretically motivated claim is that although each instance has a predicational aspect as well as a universal one, it is simple in the sense of lacking internal predicative structure; though, this claim can be called into question. Keywords: analytic ontology, moderate nominalism, moderate realism, particular, universal, abstract, concrete, abstract particular, abstract universal, concrete particular, concrete universal, trope, moment, complex unity, collection, instance, unit attribute, intensional aspect, predicational aspect, continuous composite, articulated composite. (shrink)

During the last decades, Ingvar Johansson has made a formidable contribution to the development of philosophy in general and perhaps especially to the development of metaphysics. This volume consists of original papers written by 50 philosophers from all over the world in honour of Ingvar Johansson to celebrate his 70th birthday. The papers cover traditional issues in metaphysics and the philosophy of mind, applied ethics and applied metaphysics, the nature of human rights, the philosophy of economics and sports. Some of (...) the papers study the philosophy of Ingvar Johansson.All of them studies subjects which he has shown an interest in. The variety of subjects covered, testifies to the extraordinary wide range of issues his thought has had a bearing on. (shrink)

Platelet‐derived growth factor (PDGF) was originally identified in platelets and in serum as a mitogen for fibroblasts, smooth muscle cells (SMC) and glia cells in culture. PDGF has since expanded to a family of dimers of at least four gene products, whose biological actions are mediated through two receptor tyrosine kinases, PDGFRs. The present review summarizes and discusses the biological functions of PDGFs and PDGFRs in developmental processes, mainly as revealed through genetic analysis in mice. Such studies have demonstrated multiple (...) critical roles of PDGFs and PDGFRs in embryonic and postnatal development. PDGFs seem to act upon specific populations of progenitor cells that give rise to several different cell types with distinct functions in a variety of developmental processes. Analogies are seen between the cell functions and the developmental processes controlled by PDGFs. This suggests that ancestral PDGF and PDGFR expression patterns and functions may have been iterated in related sets of morphogenetic processes in the course of evolution. BioEssays 23:494–507, 2001. © 2001 John Wiley & Sons, Inc. (shrink)

To a large extent liability for ICT perils is still a grey area, even though an increasing number of information security researchers adopt economic approaches to highlight market mechanisms and externalities. That is why this article focuses on the need for increased awareness of externalities and liability among ICT professionals and their customers. This is critical to achieve in order to promote appropriate ICT technologies and services with comprehensible privacy and security protection. What is needed is a better understanding of (...) the consequences of externalities from ICT perils. This would benefit customers and increase trust in ICT products and services which in turn may even increase suppliers' profit margin; customers would be prepared to buy more services and products if contracts and service level agreements would accept more liability. Moreover, suppliers could sell guaranties and insurances on top of their products and services. The result would be a win-win situation and would benefit society at large. (shrink)

In Ostia, Rome's harbour-town, several parts of an inscription which reveals that the Emperor Vespasian promoted the town's water supply were found in 1983. Eventually references to the text began to circulate, then one more fragment turned up and in 2006 the formal and official publication of the text took place, for which the scholarly world is grateful to Alfredo Marinucci.

Ever since its formative years in the USA a century ago, the discipline of education has taken an uneasy stand on its own ‘scientific’ status, not least with regard to the basic issue of the relationships between theory and practice. When a science of education was introduced as a panacea for rational planning in the fields of schooling and teacher training, general solutions on a scientific basis were to underpin efficient steering at all levels. Presently, there are signs of similar (...) approaches to science in federal policies concerned with evidence‐based educational practice in the USA. At the same time a new conception of educational science has been launched in Sweden as a means to promote more fruitful research. With the background of some striking similarities as well as differences among dominant conceptions of educational science in these varying contexts, this article aims to reconsider some basic aspects of the persistent issue of the relationships between pedagogic theory and practice. (shrink)

Ever since its formative years in the USA a century ago, the discipline of education has taken an uneasy stand on its own ‘scientific’ status, not least with regard to the basic issue of the relationships between theory and practice. When a science of education was introduced as a panacea for rational planning in the fields of schooling and teacher training, general solutions on a scientific basis were to underpin efficient steering at all levels. Presently, there are signs of similar (...) approaches to science in federal policies concerned with evidence‐based educational practice in the USA. At the same time a new conception of educational science has been launched in Sweden as a means to promote more fruitful research. With the background of some striking similarities as well as differences among dominant conceptions of educational science in these varying contexts, this article aims to reconsider some basic aspects of the persistent issue of the relationships between pedagogic theory and practice. (shrink)

This article connects the previously isolated literatures on corporate citizenship and corporate political activity to explain how firms construct political influence in the public sphere. The public engagement of firms as political actors is explored empirically through a discursive analysis of a public debate between the mining industry and the Australian government over a proposed tax. The findings show how the mining industry acted as a corporate citizen concerned about the common good. This, in turn, legitimized corporate political activity, which (...) undermined deliberation about the common good. The findings explain how the public sphere is refeudalized through corporate manipulation of deliberative processes via what we term corporate citizenspeak—simultaneously speaking as corporate citizens and for individual citizens. Corporate citizenspeak illustrates the duplicitous engagement of firms as political actors, claiming political legitimacy while subverting deliberative norms. This contributes to the theoretical development of corporations as political actors by explaining how corporate interests are aggregated to represent the common good and how corporate political activity is employed to dominate the public sphere. This has important implications for understanding how corporations undermine democratic principles. (shrink)

This article attempts to understand and develop the morality of everyday activities in organizations. Aristotle’s concept of phronesis, practical wisdom, is utilized to describe the morality of the everyday work activities at two call centres of an Australian insurance company. The ethnographic data suggests that ethical judgements at the lower level of the organization are practical rather than theoretical; emergent rather than static; ambiguous rather than clear-cut; and particular rather than universal. Ethical codes are of limited value here and it (...) is argued that by developing phronesis members of the organization can improve their capacity to deal with this ethical complexity. (shrink)

Everyone says that lying is wrong. But when we say that lying is bad and hurtful and that we would never intentionally tell a lie, are we really deceiving anyone? In this wise and insightful book, David Nyberg exposes the tacit truth underneath our collective pretense and reveals that an occasional lie can be helpful, healthy, creative, and, in some situations, even downright moral. _The Varnished Truth_ takes us beyond philosophical speculation and clinical analysis to give us a sense (...) of what it really means to tell the truth. As Nyberg lays out the complexities involved in leading a morally decent life, he compels us to see the spectrum of alternatives to telling the truth and telling a clear-cut lie. (shrink)

The Varnished Truth gives us a careful, spirited, and fresh look at the multi-layered subject of deception and truth-telling in everyday life.

The aim of the article is to analyse the relationship between Quaternary geology, the idea of land elevation, nationalism and regionalism in Scandinavia, with special regard to the contribution of Swedish geologists at the end of the nineteenth century. From a scientific point of view, the idea of land elevation was connected to the acceptance of the glaciation theory and the elevation theory of Thomas F. Jamieson, but analysed in a wider cultural context it is possible to understand both the (...) professionalization of Quaternary geology and the new theory of shore-line displacement as expressions of Swedish cultural nationalism. As a complement to the specific cultural history, the Quaternary geology enterprise was a way of constituting a unique natural history of the nation. One of the new theories that developed in this process was that of the Highest Marine Border, a complex concept established by the distinguished geologist Gerard De Geer at the end of the 1880s in order to defend the theory of land elevation, which was threatened by the work of Eduard Suess. The line was considered to be a geographical border that both expressed the elevation pattern and sharply divided Sweden into one part that had been covered by water during the post-glacial period and another part that had not. The study continues by looking more closely at the construction of the border in the north of Sweden. Through an account of a subsequent scientific dispute between De Geer and the geologist Arvid Gustaf Hogbom it is clear that the concept of the Highest Marine Border was shaped not only by nationalism but also by regionalism. (shrink)

The brain networks underlying human multiple-cue judgment, the judgment of a continuous criterion based on multiple cues, have been examined in a few recent studies, and the ventral precuneus has been found to be a key region. Specifically, activation differences in ventral precuneus (as measured with functional magnetic resonance imaging, fMRI) has been linked to an exemplar-based judgment process, where judgments are based on memory for previous similar cases. What aspects of exemplar-based judgment ventral precuneus supports is however poorly understood. (...) Ventral precuneus is a brain region important for various episodic memory processes, where increased engagement of this region together with the ventromedial prefrontal cortex (vmPFC) and the medial temporal lobes (MTL) during learning have been linked to retrieval success. Several alternatives are plausible, for example that reduced brain activity in ventral precuneus during learning to make exemplar-based judgments could reflect reduced needs for visuo-spatial attention as a function of learning to master the task. The present study used fMRI during a multiple-cue judgment task to gain novel neurocognitive evidence informative for the link between learning-related activity changes in ventral precuneus and exemplar-based judgment. Participants (N = 27) spontaneously learned to make judgments during fMRI, in a multiple-cue judgment task specifically designed to induce exemplar-based processing. Contrasting brain activity during late learning to early learning indeed revealed higher activity in ventral precuneus, the bilateral MTL and the vmPFC. Activity in the ventral precuneus and the vmPFC was found to parametrically increase between each judgment event, and activity levels in the ventral precuneus predicted performance after learning. These results are interpreted such that the ventral precuneus supports the aspects of exemplar-based processes that are related to episodic memory, tentatively by building and retrieving memory representations for judgment. (shrink)

We further develop the mathematical theory of causal interventions, extending earlier results of Korb, Twardy, Handfield, & Oppy, (2005) and Spirtes, Glymour, Scheines (2000). Some of the skepticism surrounding causal discovery has concerned the fact that using only observational data can radically underdetermine the best explanatory causal model, with the true causal model appearing inferior to a simpler, faithful model (cf. Cartwright, (2001). Our results show that experimental data, together with some plausible assumptions, can reduce the space of viable explanatory (...) causal models to one. (shrink)

This study is concerned with the productive aspects of confabulation as it occurs spontaneously in dementia care, in its context, and in interaction with other care recipients. Confabulation is approached as a social and discursive event with distinct narrative features; plots and formerly established genres of plots, storylines, are used by confabulators in order to understand, manage and interact socially in the present situation. Three main functions of confabulation are discerned: 1) making sense of the current situation ; 2) maintaining (...) a personal identity in interaction with others ; and 3) organizing and legitimizing joint action in the world. The resources used by confabulating subjects are sparse and not well adjusted to changing conditions, as the number of accessible storylines is limited. This makes it difficult to apply storylines that explain the current situation satisfactorily, provide useful guidelines for how to act, as well as preserve a positive self-identity. Helping with this constitutes a major challenge in dementia care. (shrink)

Proceedings of an International Conference held in Trondheim, Norway, 10th-12th October 2008, arranged by the Institute of Archaeology and Religious Studies, and the SAK department of the Museum of Natural History and Archaeology of the Norwegian University of Science and Technology (NTNU) A volume dedicated to the achievements of Norwegian archaeologist Gutorm Gjessing (1906-1979).

Discusses the nature of power, describes its psychological and social aspects, and speculates about the relationship between power and freedom.

abstract: Numerous authors have compared Process thought as articulated by Alfred North Whitehead and Mahayana Buddhist philosophy, owing to the fact that each of these systems is rooted in the notion that relational action, rather than substance, is meta-physically fundamental and that human life is to be understood as fundamentally experiential. However, despite the fact that the foundational philosophical tenets of Mahayana Buddhism are built on axioms established and rooted in early Buddhism, relatively little has been written comparing Process thought (...) with the philosophy of early Buddhism. In this essay, I first offer a brief comparison and discussion of the foundational metaphysical principles of these systems. The purpose of this essay is to extend the dialogue between Process thought and early Buddhism, highlighting both areas of convergence and points of departure. The first task is to establish how key terms in each system may be understood in terms of the other and to point out ways in which these systems converge around questions of ontology, agency, and the nature of the self. I will then discuss the epistemologies that underwrite these meta-physical commitments. Finally, I will conclude with a brief comparison of the role of aesthetics in human experience and the soteriological project within these two schools of thought. (shrink)

Kaila, E. Arkikokemuksen perseptuaalinen ja konseptuaalinen aines.--Nevalinna, R. Kokeista ja ajatuskokeista.--Stenius, E. Kielellinen rakenne ja kokemusmaailman rakenne.--Stenius, E. Modus ja kielipeli.--Wright, G. H. von. Praktinen päättely.--Wright, G. H. von. Lupauksista.--Hintikka, J. Deonttisen logiikan ongelmia.--Hintikka, J. Ovatko kaikki loogiset totuudet analyyttisiä?--Hintikka, J. Havainnon logiikasta.--Hintikka, J. Semanttisen informaation teoriasta.