Food choices are a key determinant of dietary intake, with brain regions, such as the mesolimbic and prefrontal cortex maturing at differential rates into adulthood. More needs to be understood about developmental changes in healthy and unhealthy food perceptions and preference. We investigated how food perceptions and preference vary as a function of age and how food attributes impact age-related changes. One hundred thirty-nine participants completed computerized tasks to rate high-calorie and low-calorie food cues for taste, health, and liking, followed (...) by 100 binary food choices based on each participant’s ratings. Dietary self-control was considered successful when the healthier food was chosen. Self-control success ratio was the proportion of success trials over total number of choices. Beta-weights for health and taste were calculated as each attribute’s influence on food preference. Adiposity measurements included BMI z-score and waist-to-height ratio. High-calorie foods were rated more tasty and less healthy with increasing age. Older participants liked high-calorie foods more, and β-taste was associated with age. Significant age-by-WHtR interactions were observed for health and taste ratings of high-calorie foods, β-taste, and marginally for preference of high-calorie foods. Stratifying by WHtR, we found age-related increases in taste and preference ratings of high-calorie foods in the high WHtR group alone. In contrast, age-related decreases in health ratings of high-calorie foods were significant in the low WHtR group alone. Age and β-taste were significantly associated in the high WHtR group and only marginally significant with low WHtR. Although participants rated low-calorie foods as less tasty and less healthy with increasing age, there was no association between age and preference for low-calorie foods. Participants made faster food choices with increasing age regardless of WHtR, with a significant age-by-WHtR interaction on reaction time. There were no age-related effects in self-control success ratio and β-health. These results suggest that individual differences in age and central adiposity play an important role in preference for high-calorie foods, and a higher importance of food tastiness in food choice may contribute to greater preference for high-calorie foods with increasing age. (shrink)

RESUMEN El presente texto es el resultado de un estudio dirigido a demostrar la importancia del sistema muscular en mujeres operadas de cáncer de mama, enfermedad con elevada incidencia en Cuba y el mundo. Se investigó en los principales reportes anatómicos. Se partió de la revisión documental de textos básicos para la carrera de Medicina inherentes a la asignatura Anatomía Humana. Se corroboró que autores como M. Prives, N Lisenkov y V Bushkovich y R. D. Sinelnikov; describen los músculos, pero (...) no relatan su importancia en la práctica quirúrgica. Se emplearon los buscadores en Internet y otros sitios webs de información científica, que permitieron corroborar desde un enfoque de ciencia, tecnología y sociedad la importancia del tejido muscular y su aplicación en técnicas reconstructivas en pacientes operadas de cáncer de mama. Se constató que los músculos más usados son los rectos abdominales, los dorsales anchos, los gráciles y el tejido adiposo del pliegue glúteo. ABSTRACT The present text is the result of a study directed to demonstrate the importance of the muscular system in women who had a surgery on breast cancer, illness with high incidence in Cuba and the world. It was investigated in the principal anatomical reports. It began with the documentary review of basic texts for the career of Medicine inherent to the subject Human Anatomy. It was corroborated that authors like M. Prives, N Lisenkov and V Bushkovich and R. D. Sinelnikov; they describe the muscles, but they do not report their importance in surgical practice. It was used the searche engines on Internet and other web sites of scientific information, which allowed to corroborate from an approach of science, technology and society the importance of the muscular tissue andits application in reconstructive techniques in patients who undergoa breast cancer surgery. It was stated that the most used muscles are the abdominal rectus, the latissimusdorsi, the graceful ones and the adipose tissue of the gluteus fold. (shrink)

A prefrontal control system that is less mature than the limbic reward system in adolescence is thought to impede self-regulatory abilities, which could contribute to poor dietary choices and obesity. We, therefore, aimed to examine whether structural morphology of the prefrontal cortex and the amygdala are associated with dietary decisions and obesity in children and adolescents. Seventy-one individuals between the ages of 8–22 years participated in this study; each participant completed a computer-based food choice task and a T1- and T2-weighted (...) structural brain scans. Two indices of obesity were assessed, including age- and sex-specific body mass index and waist-to-height ratio. The behavioral task included rating 60 food stimuli for tastiness, healthiness, and liking. Based on each participant’s self-ratings, 100 binary food choices were then made utilizing a computer mouse. Dietary “self-control” was calculated as the proportion of trials where the individual chose the healthier food item over the total number of trials. Cortical thickness and amygdala subnuclei volumes were quantified using FreeSurfer 6.0 and CIT168 atlas, respectively. We found that WHtR was negatively associated with the thickness of bilateral superior frontal, left superior temporal, right insula, and right inferior temporal regions. We also found WHtR to be positively associated with the volume of the central nucleus region of the amygdala, after adjusting for the hemisphere, age, sex, and intracranial volumes. A similar data pattern was observed when BMIz was used. Moreover, we found that across all participants, thinner right superior frontal cortex and larger left CEN volumes predicted lower dietary self-control. These results suggest that differential development of the PFC and amygdala relate to obesity and dietary self-control. Further longitudinal studies are merited to determine causal relationships among altered PFC to amygdala neural circuitry, dietary self-control, and obesity. (shrink)

Se propone una reflexión sobre el método clínico y sus etapas, la relación médico-paciente y la presencia tecnológica en la Cardiología Pediátrica. La ecocardiografía transtorácica no puede sustituir el pensamiento médico, la anamnesis, ni el examen físico. Como medio diagnóstico realizado e interpretado por humanos, está sujeto a error, el cual se minimiza según la calidad de los datos clínicos aportados por el médico que lo solicita. El presente trabajo tiene como objetivo analizar los aspectos éticos del método clínico en (...) relación con la utilización de la ecocardiografía transtorácica en niños con cardiopatías congénitas. It is proposed a reflexion about the clinical method and its stages, the doctor-patient relation and the presence of technology in paediatric cardiology. The transthoracic echocardiography can4t substitute medical thought, neither the anamnesis nor the physical examination. As a diagnostic medium carried out and interpreted by humans, it is subject to error, which it is minimized according to the quality of the clinical data provided by the doctor who requests them. The present work has the objective to analyse the Ethical foundations of the clinical method in connection with the use of transthoracic echocardiography in children with congenital cardiopathies. (shrink)

Es escasa la investigación sobre las competencias necesarias para educar eficazmente en los primeros años de vida, y sobre los factores que influyen en la adquisición de una identidad docente de calidad para trabajar en Educación Infantil (EI). Los resultados de la presente revisión integradora apuntan que (1) el profesorado excelente de EI atiende a la diversidad de su alumnado, (2) las comunidades de práctica contribuyen a la adquisición de una identidad docente excelente, y (3) ciertas deficiencias en los programas (...) de formación docente y determinados factores contextuales obstaculizan un desempeño docente excelente. (shrink)

Despite the shifting ideologies of gender of the seventeenth century, the arrival of the first actresses caused deep social anxiety: theatre gave women a voice to air grievances and to contest, through their own bodies, traditional gender roles. This paper studies two of the best-known actresses, Nell Gwyn and Anne Bracegirdle, and the different public personae they created to negotiate their presence in this all-male world. In spite of their differing strategies, both women gained fame and profit in the male-dominated (...) theatrical marketplace, confirming them as the ultimate “gender benders,” who appropriated the male role of family’s supporter and bread-winner. (shrink)

En este libro (de 589 págs.) se muestra cómo Ortega descubrió la vía o método de la razón vital, que permite comprender la realidad. Gracias a este método de la razón vital, Julián Marías ha llegado a una nueva concepción de la filosofía y del cristianismo. Y por ello ha llegado a ser el "apóstol de la divina razón" justificadora tanto del cristianismo como de ese quehacer que llamamos filosofía, la cual es tan necesaria para él que sin ella nos (...) quedamos privados de los instrumentos intelectuales adecuados para comprender a Dios. Expone lo más fielmente posible la divina razón filosófica y teológica de Julián Marías, dando cuenta de su dilatada obra, dejando que él nos “hable” con los textos que escribió. El presente estudio atiende a un deseo expresado por él mismo de poner sus escritos en conexión: «cuando he publicado un libro, se ha hablado de él casi siempre como si fuese “único”, sin intentar casi nunca ponerlo en conexión con los anteriores, menos aún intentar hacer la suma. Es un carácter que valdría la pena examinar». Al poner en conexión su densa obra, este libro busca principalmente sistematizarla, así como completar con lo que dice en unos libros lo que falta, aparece solo apuntado o está en trance de maduración en otros. Porque, como todo pensador, Julián Marías tiene también sus deficiencias, una de las cuales (la principal) es que no hizo una sistematización rigurosa de su filosofía: esta fue apareciendo progresivamente en el curso de su vida hasta los últimos artículos —unos 250— que dictó al autor del presente libro. No pudo hacer esa tarea por falta de tiempo. Y porque no se daba importancia. Muchos lectores resbalan sobre sus últimos libros, como "Persona" o "La perspectiva cristiana" —brevísimos porque así lo quiso su autor, que modestamente no insistía acerca de todo lo que descubren y de lo que implica cada frase— sin apenas sospechar que nos encontramos ante obras monumentales, realmente innovadoras. Realizar esa sistematización de toda su obra no es tarea fácil. En todo caso, nos damos cuenta de la genialidad de Julián Marías —que además escribe con admirable talento literario, «con su diamantina prosa» —, según la siguiente definición, en un libro suyo de literatura, a propósito de su amigo Azorín: «Un genio es quien modifica nuestra manera de ver la realidad, de tal manera que ya forma parte de nosotros» . Lejos de ser un fenómeno del pasado, esta filosofía es una posibilidad futura, particularmente de América. Como dice Harold Raley, «el pensamiento de Marías está por descubrirse. Sigue intacto y gracias a los traductores está ahí disponible en inglés con sus posibilidades expresadas con toda claridad humana y dialéctica, acaso como una bomba de tiempo que el día menos pensado estalle en manos de algún filósofo atrevido». Recensión por María Dolores de Miguel Poyard: "Julián Marías, apóstol de la divina razón", Sal Terrae 106 (2018) 645-647. Reseña por Juan Francisco Serrano: "Homenaje a Julián Marías", Alfa y Omega 1028 (2017) 27. ÍNDICE: Prólogo, por Harold Raley- I. LA FUERZA DE LA DIVINA RAZÓN- Apóstol de la divina razón- Algunos ataques clericales- Una vida intensa y llena de sentido cristiano- El último libro de Julián Marías- Ortega completado por Marías- La razón vital- La aprehensión de la realidad en su conexión- Mismidad- Divina razón de la filosofía y del cristianismo- II. DIVINA RAZÓN DE LA FILOSOFÍA- Decadencia de la filosofía- Filosofía y ciencia- Ensimismamiento- La visión responsable- Nueva metafísica (antecesora y distinta de la de Heidegger)- Descosificación de la persona- “Qué” y “quién”- Nueva visión de la persona partiendo de la auténtica traducción de "ousía"- La ilusión como potencia de personalización- Entender la realidad- Las raíces morales de la inteligencia- La realidad más importante de este mundo- La realidad radical: mi vida- Fenomenología y cosificación- Nuevo principio de individuación- Razones antropológicas ante el aborto- Verdad y perspectiva- Verdad y concordia- Educador de la convivencia- La estructura empírica de la vida humana- La moral intrínseca de la vida humana- La estructura empírica remite a su mortalidad; mi vida postula su permanencia- III. DIVINA RAZÓN DEL CRISTIANISMO- El irracionalismo teológico- Una teología «según la razón vital»- Razones de la vida de Dios- La filosofía actual y el ateísmo- Imposibilidad de la aniquilación- Amor e inmortalidad- Nueva visión de la vida perdurable- La imaginación de la vida perdurable- Antropocentrismo- Razón, imaginación literaria e inteligibilidad del Nuevo Testamento- Crisis religiosa- Tolerancia e intolerancia- Nueva comprensión de Dios y del hombre- El sustancialismo aplicado a Dios- Liberación del paganismo- Sacrificios y belleza- El apostolado de la divina razón: "Fides quaerens intellectum"- Bibliografía. (shrink)

Resumen Este artículo analiza, en discusión con Joaquín García-Huidobro y Alejandro Miranda, la conveniencia de utilizar en moral sexual el argumento de la facultad pervertida, conforme al cual sería inmoral frustrar el fin natural de las facultades reproductivas. Según García-Huidobro y Miranda este argumento sólo puede utilizarse desde el “principio de totalidad”, pues su uso aislado llevaría a los absurdos denunciados por la New Natural Law Theory. Con vistas a una reconsideración de este argumento, se demuestra la importancia de considerar (...) la ética en su carácter tópico o contextual. Así, es en el ámbito de la templanza y de las inclinaciones sexuales donde el AFP cobra un papel normativo; en cambio, el “principio de totalidad” entra en juego cuando se está considerando el problema del límite de las intervenciones médicas.This paper focuses on the adequacy of using the so-called perverted faculty argument within the context of sexual morality. According to this argument, frustrating the reproductive faculty would be immoral. Professors García-Huidobro and Miranda think that this argument can be appropriately used only within the framework of the principle of totality. They argue that an unqualified use of the PFA would lead to the absurdities pointed out by the New Natural Law Theory. In order to see the PFA in a new light we demonstrate the importance of respecting the dialectical or contextual nature of Ethics. Thus, regarding temperance, and especially sexual inclinations, the PFA has a clear normative role. The principle of totality, instead, must be used when considering the problem of the moral limits of medical interventions. (shrink)

Introduction Currently, The nature and scope of Clinical Ethics Protocols in Madrid are not well understood.Objectives The main objective is to describe the features of ‘guideline/recommendation’ type CEPs that have been or are being developed by existing Clinical Ethics Committees in Madrid. Secondary objectives include characterisation of those CECs that have been the most prolific in reference to CEP creation and implementation and identification of any trends in future CEP development.Methods We collected CEPs produced and in process by CECs accredited (...) in the public hospitals in Madrid, Spain, from 1996 to 2008.Results CECs developed 30 CEPs, with 10 more in process. The most common topic is refusal of treatment . If CEPs addressing terminal illness, Do-Not-Resuscitate orders and advance directives are placed into a separate ‘ethical problems at the end of life’ category, this CEP subject emerges as the most common . There is a relationship between the age of the CEC and the development of CEPs . CECs now seem to be more likely to engage in CEP development.Conclusions The CECs in Madrid, Spain, have developed a significant number of CEPs and there is a trend towards continued development. The most frequent topics are ethical problems at the end of life and refusal of treatment by the patient. (shrink)

This paper investigates the role that universities play in supporting social entrepreneurs (SEs) across their ecosystem. Adopting the resource-based view (RBV) approach, we argue that universities attract, mobilize, and deploy multiple resources that benefit SEs through four main mechanisms (i.e., teaching, research, outreach, and the development of partnerships). We use a qualitative approach of 62 semi-structured interviews and 8 focus groups in Ecuador, Bolivia, and Colombia. Our contribution shows that employing different resources and engaging in supportive activities of universities towards (...) SEs facilitate the development of university capabilities, such as an increased reputation, development of leadership skills for students and staff, and wider access to ecosystem resources that support other university activities related to teaching, research, and community outreach. The role that partnerships play in the development of these capabilities is fundamental, thanks to the different strategic alliances and mobilization of resources between universities and other actors while supporting SEs. This study contributes to our understanding of the role universities can play to intensify the nature of supportive ecosystems for SEs. This contribution is relevant not only to academics but also to practitioners, as this will shed light on the building, development, and scaling of a supportive ecosystem for SEs. (shrink)

In this article, we present results from a literature review of intrinsic, instrumental, and relational values of nature conducted for the Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services, as part of the Methodological Assessment of the Diverse Values and Valuations of Nature. We identify the most frequently recurring meanings in the heterogeneous use of different value types and their association with worldviews and other key concepts. From frequent uses, we determine a core meaning for each value type, which is (...) sufficiently inclusive to serve as an umbrella over different understandings in the literature and specific enough to help highlight its difference from the other types of values. Finally, we discuss convergences, overlapping areas, and fuzzy boundaries between different value types to facilitate dialogue, reduce misunderstandings, and improve the methods for valuation of nature's contributions to people, including ecosystem services, to inform policy and direct future research. © 2023 The Author(s). Published by Oxford University Press on behalf of the American Institute of Biological Sciences. (shrink)

John Locke's philosophy was deeply affected by medicine of his times. It was specially influenced by the medical thought and practice of Thomas Sydenham. Locke was a personal friend of Sydenham, expressed an avid interest in his work and shared his views and methods. The influence of Sydenham's medicine can be seen in the following areas of Locke's philosophy: his “plain historical method”; the emphasis on observation and sensory experience instead of seeking the essence of things; the rejection of hypotheses (...) and principles; the refusal of research into final causes and inner mechanisms; the ideal of irrefutable evidence and skepticism on the possibilities of certainty in science. The science which for Locke held the highest paradigmatic value in his theory of knowledge was precisely medicine. To a great extent, Locke's Essay on Human Understanding can be understood as an attempt to justify, substantiate, and promote Sydenham's medical method. This method, generalized, was then proposed as an instrument for the elaboration of all natural sciences. (shrink)

In this article I compare the phenomenology of Husserl with Polo’s philosophy of the mental limit. This comparison is orientated to highlight the importance of habits in anthropology.

Justo antes de la pandemia por COVID-19, la Organización Mundial de la Salud definió unas prioridades de trabajo para la década 2020-2030. Un grupo interdisciplinario de profesionales de la salud reflexiona sobre estas prioridades, determinando unas categorías de análisis y, desde una perspectiva bioética, analiza cada una de ellas, ve su pertinencia, algunos eventos causales, las implicaciones que pueden tener si no son enfrentadas adecuadamente y hace sugerencias sobre la forma de llevarlas a cabo. En esta primera entrega se analiza (...) el primer grupo de prioridades estratégicas: “poblaciones más sanas”. En las conclusiones se destaca la conveniencia de acometer cada una de ellas de una manera colaborativa, gubernamental y privada; de reestructurar el sector salud con base en estas prioridades, aprovechando la experiencia obtenida en la lucha contra el COVID-19. La relación del ser humano con el medio ambiente también debe cambiar, apelando a la responsabilidad humana por el cuidado del planeta. (shrink)

En este artículo se examinan las referencias a Escoto de la obra poliana, y se discute en especial el voluntarismo escotísta que reduce el horizonte humano a su actividad esencial.

We seek in this work to make a succinct exposition of the keys of the modal ontology of Leibniz, showing their connection with other modern thinkers; and also to take out to the light some of the problems that the modal metaphysics of Leibniz, in particular about the existential judgment.

El objetivo del presente trabajo es poner en diálogo la filosofía poliana del límite mental con el criticismo de Kant. Mantengo que por comenzar desde el hecho de que ellos toman el mismo método como tema, ambas posiciones teóricas están interconectadas. La limitación del conocimiento, el problema de su fundamentación, y la antropología que responde a ambas cuestiones será objeto de estudio del presente artículo.

El olvido kantiano de la inmanencia cognoscitiva es solidario de la existencia empírica que Kant concede a las cosas, y a ello se debe la construcción kantiana del objeto de experiencia para la comprensión de lo dado en el espacio y en el tiempo; así se forja la distinción fenómeno-noúmeno. En cambio, la noción poliana de límite mental justifica mejor la facticidad de lo que hay en el mundo, ante el hombre; y permite tomarse la libertad de abandonarlo para descubrir (...) la inteligibilidad de la existencia. (shrink)

Se plantea en este trabajo la distinción entre ciencia y filosofía, tanto desde un punto de vista metódico como desde otro temático. Frente a una posible fundamentación de la ciencia en la filosofía, se sugiere una posible conciliación de ambas, que mantenga su diferencia, en el conocimiento matemático.

Desde la noción poliana de "ser además" este trabajo busca en la idea escolástica de hábitos entitativos de la persona una suficiente comprensión de la apertura de la persona humana hacia fuera y hacia dentro que propone la antropología poliana.

We performed an EEG graph analysis on data from 31 typical readers and 24 dyslexics, recorded while they were engaged in an audiovisual task and during resting-state. The task simulates reading acquisition as participants learned new letter-sound mappings via feedback. EEG data was filtered for the delta, theta, alpha, and beta bands. We computed the Phase Lag Index to provide an estimate of the functional connectivity between all pairs of electrodes per band. Then, networks were constructed using a Minimum Spanning (...) Tree, a unique sub-graph connecting all nodes without loops, aimed at minimizing bias in between groups and conditions comparisons. Both groups showed a comparable accuracy increase during task blocks, indicating that they correctly learned the new associations. The EEG results revealed lower task-specific theta connectivity, and lower theta degree correlation over both rest and task recordings, indicating less network integration in dyslexics compared to typical readers. This pattern suggests a role of theta oscillations in dyslexia and may reflect differences in task engagement between the groups, although robust correlations between MST metrics and performance indices were lacking. (shrink)