BackgroundPreprint usage is growing rapidly in the life sciences; however, questions remain on the relative quality of preprints when compared to published articles. An objective dimension of quality that is readily measurable is completeness of reporting, as transparency can improve the reader’s ability to independently interpret data and reproduce findings.MethodsIn this observational study, we initially compared independent samples of articles published in bioRxiv and in PubMed-indexed journals in 2016 using a quality of reporting questionnaire. After that, we performed paired comparisons (...) between preprints from bioRxiv to their own peer-reviewed versions in journals.ResultsPeer-reviewed articles had, on average, higher quality of reporting than preprints, although the difference was small, with absolute differences of 5.0% [95% CI 1.4, 8.6] and 4.7% [95% CI 2.4, 7.0] of reported items in the independent samples and paired sample comparison, respectively. There were larger differences favoring peer-reviewed articles in subjective ratings of how clearly titles and abstracts presented the main findings and how easy it was to locate relevant reporting information. Changes in reporting from preprints to peer-reviewed versions did not correlate with the impact factor of the publication venue or with the time lag from bioRxiv to journal publication.ConclusionsOur results suggest that, on average, publication in a peer-reviewed journal is associated with improvement in quality of reporting. They also show that quality of reporting in preprints in the life sciences is within a similar range as that of peer-reviewed articles, albeit slightly lower on average, supporting the idea that preprints should be considered valid scientific contributions. (shrink)

Apresentação / Pablo Lorenzano Introdução / Os editores Princípios em cosmologia / Antonio Augusto Passos Videira Aleatoriedad vs. arbitrariedad en la mecánica estadística clásica / Eduardo H. Flichman La teoría galileana de la materia: resolutio e infinitos indivisibles / Fernando Tula Molina Ciencia y música en la obra de Vincenzo Galilei (ca. 1520-1591) / Guillermo Boido & Eduardo Kastika T-invariancia, irreversibilidad, flecha del tiempo: similares pero diferentes / Olimpia Lombardi Mapa das interpretações da teoria quântica / Osvaldo Pessoa Jr. Aspectos (...) epistemológicos y geométricos de la teoría del campo unificado de Schrödinger / Victor Rodríguez & Pedro W. Lamberti. (shrink)

This paper contains a survey of the main definitions and results obtained to date related to Temporal Equilibrium Logic, a nonmonotonic hybrid approach that combines Equilibrium Logic (the best-known logical characterisation for the stable models semantics of logic programs) with Linear-Time Temporal Logic.

Arbuscular mycorrhiza (AM), a type of plant‐fungal endosymbiosis, and nodulation, a bacterial‐plant endosymbiosis, are the most ubiquitous symbioses on earth. Recent findings have established part of a shared genetic basis underlying these interactions. Here, we approach root endosymbioses through the lens of the homology and modularity concepts aiming at further clarifying the proximate and ultimate causes for the establishment of these biological systems. We review the genetics that underlie interspecific signaling and its concomitant shift in genetic programs for either partner. (...) Also, through the comparative analysis of genetic modules shared by AM and nodulation symbioses, we identify fundamental nodes in these networks, suggesting the elemental steps that may have permitted symbiotic adaptation. Here, we show that this approach, allied to recent technical advances in the study of genetic systems architecture, can provide clear testable hypotheses for the advancement of our understanding on the evolution and development of symbiotic systems. (shrink)

In this paper, we study the introduction of modal past temporal operators in Temporal Equilibrium Logic, an hybrid formalism that mixes linear-time modalities and logic programs interpreted under stable models and their characterisation in terms of Equilibrium Logic. We show that Kamp’s translation can also be used to translate the new extension of TEL with past operators into Quantified Equilibrium Logic. Additionally, we provide a method for removing past operators that consists in replacing past-time subformulas by fresh auxiliary atoms, obtaining (...) an equivalent formula, modulo the original alphabet. (shrink)

An accessible, higher-level introduction to a key selection of continental European thinkers from Spinoza to Zizek. Covering 'classical' exponents of the tradition such as Hegel and Marx, 'moderns' like Gramsci and Habermas and 'postmoderns' like Lacan and Deleuze, the volume introduces the main ideas of each thinker and reflects on their enduring theoretical relevance. The impressive breadth and contemporary angle make this a unique, up-to-date collection that will be invaluable to students and teaching staff alike.

1. Reasoning about action and change, or more generally reasoning about dynamic systems, is not only central to knowledge representation and reasoning but at the heart of computer science (Fisher e...

There can be no doubt that discrimination based on sex, race, ethnicity, religion or beliefs should not be tolerated in academia. Surprisingly, however, in recent years, policies of Diversity, Inclusion and Equity (DIE), officially introduced to counteract discrimination, have increasingly led to quite the opposite result: the exclusion of individuals who do not share a radical 'woke' ideology on identity politics (feminism, other gender activisms, critical race theory, etc.), and to the suppression of the academic freedom to discuss such dogmas. (...) This subversion of academia — disguised Trojan-horse style as universal human rights advocacy — is unacceptable because academia must be politically neutral and protect freedom of speech, a cornerstone of professional scholarly activity without which universities as we know them will slowly but surely suffocate. Our purpose here is to put together some particularly illustrative cases of such repression in a single book, testifying to a ubiquitous trend within western culture, irreducible to a few isolated complaints. The essays contained here illustrate the abuse of power, censorship and witch-hunts at many universities and research centres in the name of DIE. List of coauthors in alphabetical order: Dorian Abbot, Tomonori Agoh, Gerhard Amendt, Ivar Arpi, David Benatar, Peter Boghossian, Civitas Research Team, David Díaz Pardo de Vera, Pedro Domingos, Janice Fiamengo, Étienne Forest, Jorge Gibert Galassi, Norman Goldstuck, José L. González Quirós, Lawrence M. Krauss, Patrick LaBelle, Martín López Corredoira, Heather Mac Donald, Martin Malmgren, Jordan Peterson, Constantin Polychronakos, Erik. J. Olsson, Philip C. Salzman, Alessandro Strumia, Tom Todd, Andrei Yafaev. (shrink)

Near the end of 2015, Luis Fariñas del Cerro officially retired as directeur de recherche in the Centre National de Recherche Scientifique (CNRS) and became an Emeritus researcher of the CNRS. The present special issue is a Festschrift in his honour to celebrate Luis’s achievements in science, both as an outstanding scholar as well as a remarkable and highly successful organiser, administrator and leader in science and technology policy and management, in particular as the founder of the Journal of Applied (...) Non-Classical Logics. The issue contains 13 scientific contributions by 32 authors, among them Luis’s colleagues, former students and friends. Preceding versions of these papers were presented at the international workshop ‘Logical Reasoning and Computation’ that was held at IRITInstitut de Recherche en Informatique de Toulouse, Université Paul Sabatier, Toulouse, on 3–4 March 2016. The present introduction contains a short scientific biography describing the many different areas of logic and computation where Luis contributed significant advances. (shrink)

We argue that explanationist views in epistemology continue to face persistent challenges to both their necessity and their sufficiency. This is so despite arguments offered by Kevin McCain in a paper recently published in this journal which attempt to show otherwise. We highlight ways in which McCain’s attempted solutions to problems we had previously raised go awry, while also presenting a novel challenge for all contemporary explanationist views.

In 2014 the Essex Autonomy Project undertook a six month project, funded by the AHRC, to provide technical advice to the UK Ministry of Justice on the question of whether the Mental Capacity Act is compliant with the United Nations Convention on the Rights of Persons with Disabilities. Over the course of the project, the EAP research team organised a series of public policy roundtables, hosted by the Ministry of Justice, and which brought together leading experts to discuss and debate (...) the issues. A one-day public conference was held at the Institute for Government in July. In September 2014, the EAP research team submitted its findings to the Ministry of Justice. (shrink)

Planctomycetes, Verrucomicrobia and Chlamydia are prokaryotic phyla, sometimes grouped together as the PVC superphylum of eubacteria. Some PVC species possess interesting attributes, in particular, internal membranes that superficially resemble eukaryotic endomembranes. Some biologists now claim that PVC bacteria are nucleus‐bearing prokaryotes and are considered evolutionary intermediates in the transition from prokaryote to eukaryote. PVC prokaryotes do not possess a nucleus and are not intermediates in the prokaryote‐to‐eukaryote transition. Here we summarise the evidence that shows why all of the PVC traits (...) that are currently cited as evidence for aspiring eukaryoticity are either analogous (the result of convergent evolution), not homologous, to eukaryotic traits; or else they are the result of horizontal gene transfers. (shrink)

Hoy, desde muy diferentes lugares, se exige democracia. Se utiliza además un medio hasta ahora poco presente en la lucha política: la red, lo que dota de gran visibilidad a movimientos de otro modo ignorados. Así ha aparecido un doble mito: Que Internet garantiza la democracia; que permite la participación directa e ilustrada de la mayoría de la población. Sin embargo, los movimientos de 2011 lo demuestran, el destino de la democracia se juega en un terreno real caracterizado por la (...) desigualdad en la distribución de recursos y la escasa participación de la ciudadanía. (shrink)

Este repertorio registra los artículos sobre Platón que se encuentran en la Hemeroteca de la Biblioteca Central de la Pontificia Universidad Católica del Perú. El listado abarca las publicaciones existentes hasta el primer semestre del año 2000.

This paper continues a recent exchange in this journal concerning explanationist accounts of epistemic justification. In the first paper in this exchange, Byerly argues that explanationist views judge that certain beliefs about the future are unjustified when in fact they are justified. In the second paper, McCain defends a version of explanationism which he argues escapes Byerly’s criticism. Here we contribute to this exchange in two ways. In the first section, we argue that McCain’s defense of explanationism against Byerly’s objection (...) is unsuccessful. Then, in the second section, we develop an independent objection to explanationism from a different direction. If our arguments in each section are sound, then not only do explanationist accounts of epistemic justification judge beliefs that are justified to be unjustified, but they judge beliefs that are unjustified to be justified. Explanationism faces problems on both sides. (shrink)

Tanto la explicación de sentido de la modernidad como el lenguaje de la posmodernidad han rechazado la noción de presente intemporal conocida otrora por la filosofía. Aquí se quiere mostrar en qué sentido y por qué razón el novísimo pensamiento logotectónico permite recuperar aquella noción merced a una nueva distinción del presente.

El siguiente informe pericial se basa en la experiencia de investigación de los firmantes en relación a las exhumaciones de fosas comunes de la Guerra Civil y la postguerra, y al conocido como “movimiento para la recuperación de la memoria histórica” que están teniendo lugar en España desde el año 2000, que ha enfatizado sus demandas sobre la suerte de los desaparecidos y ha puesto en marcha un ciclo de exhumaciones de fosas comunes derivadas de la Guerra Civil y la (...) dictadura. En este peritaje se usan las exhumaciones del siglo XXI como indicadores de la persistencia en el tiempo de las políticas y culturas del miedo instaladas en la sociedad española durante la Guerra Civil y la dictadura, más allá de las profundas transformaciones políticas e institucionales acaecidas en el país tras la muerte de Francisco Franco. Fue presentado como parte de la documentación de la demanda de Fausto Canales contra España el 15 de septiembre de 2012 en el Tribunal Europeo de Derechos Humanos. (shrink)

In recent years, questions about epistemic reasons, norms and goals have seen an upsurge of interest. The present volume brings together eighteen essays by established and upcoming philosophers in the field. The contributions are arranged into four.

El artículo reflexiona sobre la elaboración de un peritaje antropológico realizado conjuntamente por cinco antropólogos en relación con un procedimiento seguido en el Tribunal Europeo de Derechos Humanos contra el España sobre el posible desasistimiento de las víctimas del franquismo. Se plantean los efectos sobre la escritura antropológica de este tipo de peritajes, así como sobre la propia investigación y, particularmente, sobre los efectos que para la teoría y la práctica tiene este tipo de intervención directa de la teoría en (...) el espacio público. (shrink)

Esta investigación de corte cualitativo realiza una revisión sistemática para conocer cuáles son los factores que dificultan y favorecen el proceso de aprendizaje del alumnado sordo bilingüe en primaria. Este trabajo sigue las pautas de la declaración PRISMA. Las bases de datos consultadas han sido Web of Science, Scopus, ERIC y Google Scholar revisándose en total 190 estudios empíricos, en español y en inglés, entre los años 1997 y 2021. Los resultados obtenidos muestran que hay escasas publicaciones al respecto y (...) se evidencia la necesidad de dar a conocer la situación de este colectivo para seguir avanzando y educando. (shrink)

There exist two notions of equivalence of behavior between states of a Labelled Markov Process (LMP): state bisimilarity and event bisimilarity. The first one can be considered as an appropriate generalization to continuous spaces of Larsen and Skou’s probabilistic bisimilarity, whereas the second one is characterized by a natural logic. C. Zhou expressed state bisimilarity as the greatest fixed point of an operator that there is such a process with an uncountable Zhou ordinal.

While outcomes for children with T-cell acute lymphoblastic leukemia have improved dramatically, survival rates for patients with relapsed/refractory disease remain dismal. Prior studies indicate that glucocorticoid resistance is more common than resistance to other chemotherapies at relapse. In addition, failure to clear peripheral blasts during a prednisone prophase correlates with an elevated risk of relapse in newly diagnosed patients. Here we show that intrinsic GC resistance is present at diagnosis in early thymic precursor T-ALLs as well as in a subset (...) of non-ETP T-ALLs. GC-resistant non-ETP T-ALLs are characterized by strong induction of JAK/STAT signaling in response to interleukin-7 stimulation. Removing IL7 or inhibiting JAK/STAT signaling sensitizes these T-ALLs, and a subset of ETP T-ALLs, to GCs. The combination of the GC dexamethasone and the JAK1/2 inhibitor ruxolitinib altered the balance between pro- and anti-apoptotic factors in samples with IL7-dependent GC resistance, but not in samples with IL7-independent GC resistance. Together, these data suggest that the addition of ruxolitinib or other inhibitors of IL7 receptor/JAK/STAT signaling may enhance the efficacy of GCs in a biologically defined subset of T-ALL.Leukemia advance online publication, 30 May 2017; doi:10.1038/leu.2017.136. (shrink)

Different theoretical approaches highlight the growing relevance of corporate reputation as strategic factor. Among these approaches the arguments of the Resource-Based View are special worthwhile (Grant, 1991, California Management Review33(3), 114–135; Barney, 1999, Sloan Management Review Spring, 137–145). Nevertheless, this topic poses several methodological problems (Barney et al., 2001), as the unavailability to identify and measure this organizational factor, that is “socially complex” and intangible in its nature. In this work, using the findings of our empirical research on Spanish biotechnology (...) firms, we carry out an identification and measurement of corporate reputation, highlighting its two key components: “business reputation” and “social reputation”. (shrink)

En el marco del diagnóstico acerca de la obsolescencia de las categorías fundacionales de la sociología, este trabajo repara en la noción de integración de Talcott Parsons, uno de los focos de ataque predilectos de quienes se alinean en esas concepciones. Para ello, se explora su formulación conceptual en los distintos períodos en que se subdivide su Teoría General de la Acción —Teoría Voluntarista de la Acción; Modelo Trisistémico; Esquema AGIL— para demostrar que, aunque con variaciones, siempre es el concepto (...) clave para responder la pregunta acerca de las condiciones de posibilidad del orden social. Luego, se exponen dos críticas de distinta índole: una, expone algunos argumentos de los autores que postulan su caducidad, comparándolos con la formulación de Parsons; la otra aborda otro conjunto de autores diferentes, que promueven su reconceptualización a luz de la distinción entre integración sistémica e integración social. Finalmente, se defiende la pertinencia de la noción de integración en tanto herramienta heurística clave del lenguaje sociológico. (shrink)