In recent years, more and more people are applying Convolutional Neural Networks to the study of sound signals. The main reason is the translational invariance of convolution in time and space. Thereby the diversity of the sound signal can be overcome. However, in terms of sound direction recognition, there are also problems such as a microphone matrix being too large, and feature selection. This paper proposes a sound direction recognition using a simulated human head with microphones at both ears. Theoretically, (...) the two microphones cannot distinguish the front and rear directions. However, we use the original data of the two channels as the input of the convolutional neural network, and the resolution effect can reach more than 0.9. For comparison, we also chose the delay feature (GCC) for sound direction recognition. Finally, we also conducted experiments that used probability distributions to identify more directions. (shrink)

Bromodomain‐containing 4 (BRD4), a member of Bromo and Extra‐Terminal (BET) family, recognizes acetylated histones and is of importance in transcription, replication, and DNA repair. It also binds non‐histone proteins, DNA and RNA, contributing to development, tissue growth, and various physiological processes. Additionally, BRD4 has been implicated in driving diverse diseases, ranging from cancer, viral infection, inflammation to neurological disorders. Inhibiting its functions with BET inhibitors (BETis) suppresses the progression of several types of cancer, creating an impetus for translating these chemicals (...) to the clinic. The diverse roles of BRD4 are largely dependent on its interaction partners in different contexts. In this review we discuss the molecular mechanisms of BRD4 with its interacting partners in physiology and pathology. Current development of BETis is also summarized. Further understanding the functions of BRD4 and its partners will facilitate resolving the liabilities of present BETis and accelerate their clinical translation. (shrink)

This paper studies the way supplier firms’ corporate social responsibility (CSR) affects their likelihood of being selected as new suppliers. Using a large sample of US public firms with detailed supply chain and CSR data, we provide empirical evidence that corporate customers prefer socially responsible suppliers, and that the effect is more prominent when the supplier industry is more competitive, the customer’s own CSR performance is better, or the supplier and the customer have more similar CSR focuses. Our paper contributes (...) to the literature of instrumental stakeholder theory (IST) by confirming corporate customer attraction as a desirable outcome of supplier CSR engagement. It complements the existing IST studies on customer responses by showing that CSR attracts not only final customers but also corporate customers. Moreover, by focusing on corporate customers’ revealed preferences for socially responsible suppliers, our paper also complements the stated-preference-based evidence in the literature of sustainable supply chain management. Our paper’s findings encourage supplier firm managers to invest in CSR to gain competitive advantages in the form of a higher likelihood of selection while simultaneously making positive contributions to society. (shrink)

This paper endeavors to appraise scholarly works from the 1940s to the contemporary era, examining the scientific quest to transpose human cognition and consciousness into a digital surrogate, while contemplating the potential ramifications should humanity attain such an abstract level of intellect. The discourse commences with an explication of theories concerning consciousness, progressing to the Turing Test apparatus, and intersecting with Damasio’s research on the human cerebrum, particularly in relation to consciousness, thereby establishing congruence between the Turing Test and Damasio’s (...) notions of consciousness. Subsequently, the narrative traverses the evolutionary chronology of transmuting human cognition into machine sapience, and delves into the fervent endeavors to metamorphose human minds into synthetic counterparts. Additionally, theoretical perspectives from the domains of philosophy, psychology, and neuroscience provide insight into the constraints intrinsic to AI implementations, contentious hypotheses, the perils concealed within artificial networks, and the ethical considerations necessitated by AI frameworks. Furthermore, contemplation of prospective repercussions facilitates the refinement of strategic approaches to safeguard our future Augmented Age Realities within AI, circumventing the prospect of inhabiting an intimidating technopolis where a mere 30% monopolize the intellect and ingenuity of the remaining 70% of human minds. (shrink)

Tao Te Ching sacred text, written in China around 600 BC, recommends cultivating non-action by observing the nature of the world. Tao Te Ching first articulated the idea of Wu Wei which means do that which consists in taking no action and order will prevail. The text explains the idea that we should stop trying to force action and get comfortable doing less. Taoism is widely understood to be a single (unity), unitary philosophy, social movement, and natural act. Then, when (...) we do move, our actions are natural and energetic. It can be summarized that Taoist principles are inaction or non-action, simplicity, and living in harmony with nature then everything accomplished the desired result. Tao Te Ching delivered a treatise on how to live in the world with goodness and integrity. Perhaps if we were more aware, we would worry less and could see better what actually needs doing. Therefore, Tao Te Ching reminds us that everyone has a choice to practice self-awareness and exercise their own power in and over the world for a present peaceful life. (shrink)

Game experiments designed to test the effectiveness of reward and/or punishment incentives in promoting cooperative behavior among their participants are quite common. Results from two such recent experiments conducted in Beijing, based on the Prisoner’s Dilemma (PD) game and Public Goods Game respectively, are summarized here. The unexpected empirical outcomes for the repeated PD game, that cooperation actually decreased when the participants had the option of using a costly punishment strategy and that participants who used costly punishment in some round (...) of the repeated game often did so in the first round, are discussed in terms of differences in attitudes toward reputation in Chinese culture compared to other locations (mostly in Western society) where similar experiments have been conducted. The second experiment models an institution providing incentives to increase contribution levels (i.e., cooperation) to the public good. The results show that combined institutional reward and punishment is the most effective means to increase cooperation, followed by a scheme using only punishment. It is shown how these empirical results are related to the theoretical predictions that assume players play rationally by optimizing their personal payoff given their opponents’ actions in these multi-player games. (shrink)

Students often face difficulties and experience negative emotions toward second language learning. The affective tutoring system is a next-generation learning approach that can detect the affective status of learning to increase performance. Therefore, for the purposes of this study, an innovative affective mobile language tutoring system was designed to support Japanese language learning. The effects of AMLTS, along with asynchronous discussion, that were intended to improve performance, were examined using a triangulation method. To investigate the effect on emotion, the proposed (...) AMLTS provides a virtual emotion agent that can interact with users and record emotional events, learning assessments, and the results of the interaction into a database. Learning effectiveness evaluations were conducted via two experiments: prototype evaluation and final evaluation. Sixty-three students, all beginners, were invited to use the AMLTS to learn Japanese. The research results show that the proposed AMLTS affective interaction design significantly improves learner engagement and performance. In the emotion feedback analysis and learning process, AMLTS helped students deepen their understanding of the content, enabled them to clearly understand the content, and to engage in peer interaction and experience positive emotions. In the evaluation of system usability, AMLTS reveals good usability for foreign language acquisition. (shrink)

Finding the factors driving enterprise innovation behavior from multiple dimensions is of great significance for promoting enterprise innovation. Open innovation based on overseas mergers and acquisitions has become one of the main ways for enterprises to obtain knowledge and technology. However, there is still no agreement on whether open innovation based on overseas M&A can promote innovation behavior of enterprises. Based on data from M&A transaction and enterprise patent of China’s Shanghai and Shenzhen A-share listed companies from 2011 to 2018, (...) this study constructs a propensity score matching and difference-in-difference model from the perspective of innovation performance and innovation investment empirically studies the influence of open innovation mode based on overseas M&A on the innovation behavior of enterprises and finds that open innovation based on overseas M&A can significantly promote the innovation performance and innovation investment. Meanwhile dynamic effects test shows this promotion effect is sustainable; it reaches the maximum in the year of overseas M&A and decreases in the next two years. In addition, the impacts are heterogeneous due to enterprise ownership and enterprise technology intensity. The findings extends the scope of understanding innovation behavior of enterprises from overseas M&A and provide solid evidence of significant business implications for the promotion of entrepreneurial innovation. (shrink)

The Depression Anxiety Stress Scale-21 is an instrument in the assessment of mental health status. The current study recruited 1,532 Chinese hospital workers [74.4% female; mean age = 31.97 years] to examine the reliability, latent structure, and measurement invariance of the DASS-21 between genders. The Cronbach’s α values were greater than 0.90 for total score. This study examined four possible models of the DASS-21 using the confirmatory factor analysis in Chinese hospital workers. The results from CFA revealed that the latent (...) structure of the DASS-21 in medical staffs is best represented by a one-factor model. Then we used the one-factor model to examine measurement invariance across genders by using a multiple-group categorical CFA. All values of root mean square error approximation were less than 0.08, all Comparative Fix Index and Tucker–Lewis Index values were greater than 0.90, all ΔCFI values were less than 0.010, and ΔRMSEA were less than 0.015. These findings supported the gender invariance of the DASS-21 among Chinese hospital workers. (shrink)