If definitive evidence concerning treatment effectiveness becomes available from an ongoing randomized clinical trial, then the trial could be stopped early, with the public release of results benefiting current and future patients. However, stopping an ongoing trial based on accruing outcome data requires methodological rigor to preserve validity of the trial conclusions. This has led to the use of formal interim monitoring procedures, which include inefficacy monitoring that will stop a trial early when the experimental treatment appears not to be (...) working. For participants, inefficacy monitoring is especially important as it ensures that they are not being treated worse than if they had not enrolled on the trial. We discuss the importance of reporting with trial results the formal interim inefficacy monitoring guidelines that were utilized, and, if none were used, the reasons for their absence. A survey of two leading medical journals suggests that this is not current practice. (shrink)

Die Untersuchung rekonstruiert das Subjekt in seinen kulturhistorischen Formationen als kooperationsorientierten Bewährungssucher, der sich den jeweiligen Formen des Zusammenlebens gemäß formiert, um sich in ihnen bewähren zu können. Die systematisch entwickelte Bezogenheitstheorie erlaubt die Rekonstruktion der universalen und kulturspezifischen Aspekte des Subjekts. die Untersuchung zeigt auf der Subjektebene die Bedingungen der Entfaltung modernen Zusammenlebens auf und kann von daher als eine empirisch durchgeführte Mikrosoziologie der Moderne gelten. Aus dieser kulturhistorisch gesättigten Subjekttheorie werden schließlich Schlussfolgerungen für die pädagogische Professionalität gezogen (Zum (...) Umgang mit Bewährungssuchern).​. (shrink)

Im 2009 erschienenen Buch "Philosophie des Leidens" versucht Boris Wandruszka, jene immanente Lebensstruktur und Lebensdynamik aufzudecken, die zu den einfachsten und fundamentalen Strukturmomenten des Leidens vorstosst; diese erste "Wissenschaft vom Leiden" transzendierte daher nicht die Grenzen der Anschaubarkeit, sondern verblieb in der "Immanenz des 'inneren Lebens' bzw. des Erlebens". Im aktuellen Buch "Metaphysik des Leidens" werden die "realen Bedingungen der Moglichkeit von Leiden" ermittelt: Wie muss eine Welt beschaffen sein, damit darin ein leidendes Wesen erscheinen konne? Welche Rolle hat (...) das Leiden in Bezug zum fundamentalen Widerfahrnis-, Resonanz- und Responsivitatscharakter des Lebens? Es wird gezeigt, dass menschliches Leben, das einer plural-agonalen Welt ausgesetzt ist, nicht leidfrei moglich ist, dass aber andererseits das Leid nicht das letzte Wort sein kann, sondern notwendig auf Ganzheit, Reifung, Erlosung und Harmonie bezogen ist. Nur auf dem Hintergrund der Spannung zwischen absoluter Seins-, Sinn- und Lebensfulle und der stets problematischen und fragilen Teilhabe von Menschen am "absoluten und leiduberwindenden Urleben" kann Leiden entstehen, durchlitten, verstanden, aber auch uberwunden werden. Hier erreicht der "Opfergedanke", in dem das unvermeidliche Leid frei angenommen und dadurch transformiert wird, seine reinste und hochste Ausformung. Erst nach Klarung dieser Verhaltnisse wird die "Theodizeefrage" als "das Problem der Probleme" angegangen und am Leitfaden der Hiob-Erzahlung diskutiert. Letztlich erweist sich, dass trotz allem Schmerz, Mangel, Unrecht und Unsinn ein "Potential des Unendlichen" im Leiden verborgen liegt, das auf seine Uberwindung durch Sein-, Sinn- und Werterfullung, durch Tat, Erkenntnis und Liebe verweist und dass diese drei "Machte" der Leidensherausforderung bedurfen, um ihre Weite, Tiefe und Hohe auszuloten. (shrink)

Cet ouvrage est une réédition numérique d’un livre paru au XXe siècle, désormais indisponible dans son format d’origine.

I propose a general alethic theory of epistemic risk according to which the riskiness of an agent’s credence function encodes her relative sensitivity to different types of graded error. After motivating and mathematically developing this approach, I show that the epistemic risk function is a scaled reflection of expected inaccuracy. This duality between risk and information enables us to explore the relationship between attitudes to epistemic risk, the choice of scoring rules in epistemic utility theory, and the selection of priors (...) in Bayesian epistemology more generally. (shrink)

In this handbook, I put into practice my philosophical views on children's mathematics. The handbook contains brief instructions and examples of mathematical activities. In the INSTRUCTIONS section, instructions are given on how, and in part why that way, to help preschool children in their mathematical development. In the ACTIVITIES section, there are examples of activities through which the child develops her mathematical abilities.

In this paper we develop a general theory of algorithmic fairness. Drawing on Johnson King and Babic’s work on moral encroachment, on Gary Becker’s work on labor market discrimination, and on Strawson’s idea of resentment and indignation as responses to violations of the demand for goodwill toward oneself and others, we locate attitudes to fairness in an agent’s utility function. In particular, we first argue that fairness is a matter of a decision-maker’s relative concern for the plight of people from (...) different groups, rather than of the outcomes produced for different groups. We then show how an agent’s preferences, including in particular their attitudes to error, give rise to their decision thresholds. Tying these points together, we argue that the agent’s relative degrees of concern for different groups manifest in a difference in decision thresholds applied to these groups. (shrink)

Boris Kment takes a new approach to the study of modality that emphasises the origin of modal notions in everyday thought. He argues that the concepts of necessity and possibility originate in counterfactual reasoning, which allows us to investigate explanatory connections. Contrary to accepted views, explanation is more fundamental than modality.

Many philosophers have argued that statistical evidence regarding group char- acteristics (particularly stereotypical ones) can create normative conflicts between the requirements of epistemic rationality and our moral obligations to each other. In a recent paper, Johnson-King and Babic argue that such conflicts can usually be avoided: what ordinary morality requires, they argue, epistemic rationality permits. In this paper, we show that as data gets large, Johnson-King and Babic’s approach becomes less plausible. More constructively, we build on their project and develop (...) a generalized model of reasoning about stereotypes under which one can indeed avoid normative conflicts, even in a big data world, when data contain some noise. In doing so, we also articulate a general approach to rational belief updating for noisy data. (shrink)

Approximate coherentism suggests that imperfectly rational agents should hold approximately coherent credences. This norm is intended as a generalization of ordinary coherence. I argue that it may be unable to play this role by considering its application under learning experiences. While it is unclear how imperfect agents should revise their beliefs, I suggest a plausible route is through Bayesian updating. However, Bayesian updating can take an incoherent agent from relatively more coherent credences to relatively less coherent credences, depending on the (...) data observed. Thus, comparative rationality judgments among incoherent agents are unduly sensitive to luck. (shrink)

We construct and study structures imitating the field of complex numbers with exponentiation. We give a natural, albeit non first-order, axiomatisation for the corresponding class of structures and prove that the class has a unique model in every uncountable cardinality. This gives grounds to conjecture that the unique model of cardinality continuum is isomorphic to the field of complex numbers with exponentiation.

We further investigate a divisibility relation on the set of BN ultrafilters on the set of natural numbers. We single out prime ultrafilters (divisible only by 1 and themselves) and establish a hierarchy in which a position of every ultrafilter depends on the set of prime ultrafilters it is divisible by. We also construct ultrafilters with many immediate successors in this hierarchy and find positions of products of ultrafilters.

While there are satisfactory answers to the question “How should we teach children mathematics?”, there are no satisfactory answers to the question “What mathematics should we teach children?”. This paper provides an answer to the last question for preschool children (early childhood), although the answer is also applicable to older children. This answer, together with an appropriate methodology on how to teach mathematics, gives a clear conception of the place of mathematics in the children’s world and our role in helping (...) children develop their mathematical abilities. Briefly, children’s mathematics consists of the world of children’s internal activities that they eventually purposefully organize in order to understand and control the outside world and organize their overall activities in it. We need to support a child in mathematical activities that she does spontaneously and in which she shows interest, and we need to teach her mathematics that she is interested in developing through these activities. In doing so, we must be fully aware that the child’s mathematics is part of the child’s world of internal activities and is not outside of it. We help the child develop mathematical abilities by developing them in the context of her world and not outside of it. From the point of view of this conception, the standards established today are limiting and too focused on numbers and geometric figures: these topics are too prominent and elaborated, and other mathematical contents are subordinated to them. Adhering to the standards, we drastically limit the mathematics of the child’s world, hamper the correct mathematical development of a child, and we can turn her away from mathematics. (shrink)

Analysing several characteristic mathematical models: natural and real numbers, Euclidean geometry, group theory, and set theory, I argue that a mathematical model in its final form is a junction of a set of axioms and an internal partial interpretation of the corresponding language. It follows from the analysis that (i) mathematical objects do not exist in the external world: they are our internally imagined objects, some of which, at least approximately, we can realize or represent; (ii) mathematical truths are not (...) truths about the external world but specifications (formulations) of mathematical conceptions; (iii) mathematics is first and foremost our imagined tool by which, with certain assumptions about its applicability, we explore nature and synthesize our rational cognition of it. (shrink)

We continue the research of an extension of the divisibility relation to the Stone‐Čech compactification. First we prove that ultrafilters we call prime actually possess the algebraic property of primality. Several questions concerning the connection between divisibilities in and nonstandard extensions of are answered, providing a few more equivalent conditions for divisibility in. Results on uncountable chains in are proved and used in a construction of a well‐ordered chain of maximal cardinality. Probably the most interesting result is the existence of (...) a chain of type in. Finally, we consider ultrafilters without divisors in and among them find the greatest class. (shrink)

In this paper, I make a contribution to a naturalistically-minded theory of truthmakers by proposing a solution to the nasty problem of truthmakers for negative truths. After formulating the difficulty, I consider and reject a number of solutions to the problem, including Armstrong's states of affairs of totality, incompatibility accounts, and JC Beall 's polarity view. I then defend the position that absences of truthmakers are real and are responsible for making negative truths true. According to the positive account of (...) absences I offer, absences of contingent states of affairs are causally relevant mind-independent features of the physical world, located within space and time, and capable of being discovered by scientific inquiry. Recognition of the reality of absences strengthens truthmaker theory as a naturalistic metaphysics, as truth and falsity of each and every contingent proposition finds an ontological grounding in some region of the physical universe. (shrink)

This paper analyzes the historical context and systematic importance of Kant's hypothetical use of reason. It does so by investigating the role of hypotheses in Kant's philosophy of science. We first situate Kant’s account of hypotheses in the context of eighteenth-century German philosophy of science, focusing on the works of Wolff, Meier, and Crusius. We contrast different conceptions of hypotheses of these authors and elucidate the different theories of probability informing them. We then adopt a more systematic perspective to discuss (...) Kant's idea that scientific hypotheses must articulate real possibilities. We argue that Kant's views on the intelligibility of scientific hypotheses constitute a valuable perspective on scientific understanding and the constraints it imposes on scientific rationality. (shrink)

We continue the exploration of various aspects of divisibility of ultrafilters, adding one more relation to the picture: multiplicative finite embeddability. We show that it lies between divisibility relations \ and \. The set of its minimal elements proves to be very rich, and the \-hierarchy is used to get a better intuition of this richness. We find the place of the set of \-maximal ultrafilters among some known families of ultrafilters. Finally, we introduce new notions of largeness of subsets (...) of \, and compare it to other such notions, important for infinite combinatorics and topological dynamics. (shrink)

The essential role of language in rational cognition is analysed. The approach is functional: only the results of the connection between language, reality, and thinking are considered. Scientific language is analysed as an extension and improvement of everyday language. The analysis gives a uniform view of language and rational cognition. The consequences for the nature of ontology, truth, logic, thinking, scientific theories, and mathematics are derived.

This paper discusses a novel problem at the intersection of ethics and epistemology: there can be cases in which moral considerations seem to "encroach'' upon belief from multiple directions at once, and possibly to varying degrees, thereby leaving their overall effect on belief unclear. We introduce these cases -- cases of moral encroachment under moral uncertainty -- and show that they pose a problem for all predominant accounts of moral encroachment. We then address the problem, by developing a modular Bayesian (...) framework that, we argue, is sufficiently flexible and scaleable to accommodate the multifaceted uncertainty we describe while still generating clear recommendations for an agent's beliefs. Our framework has several practical upshots, and we close by articulating them: we derive insights about the relationship between moral character and doxastic behavior and make suggestions for how to encourage people to revise their doxastic states in morally laudable ways, without deviating from core Bayesian norms. (shrink)

We investigate two questions, the relevance of memory for evaluative conditioning effects based on smell-taste pairings, and the potential preparedness of smell-taste combinations for...

We continue the research of the relation $\hspace {1mm}\widetilde {\mid }\hspace {1mm}$ on the set $\beta \mathbb {N}$ of ultrafilters on $\mathbb {N}$, defined as an extension of the divisibility relation. It is a quasiorder, so we see it as an order on the set of $=_{\sim }$ -equivalence classes, where $\mathcal {F}=_{\sim }\mathcal {G}$ means that $\mathcal {F}$ and $\mathcal {G}$ are mutually $\hspace {1mm}\widetilde {\mid }$ -divisible. Here we introduce a new tool: a relation of congruence modulo an (...) ultrafilter. We first recall the congruence of ultrafilters modulo an integer and show that $=_{\sim }$ -equivalent ultrafilters do not necessarily have the same residue modulo $m\in \mathbb {N}$. Then we generalize this relation to congruence modulo an ultrafilter in a natural way. After that, using iterated nonstandard extensions, we introduce a stronger relation, which has nicer properties with respect to addition and multiplication of ultrafilters. Finally, we introduce a strengthening of $\hspace {1mm}\widetilde {\mid }\hspace {1mm}$ and show that it also behaves well with respect to the congruence relation. (shrink)

This chapter argues that the distinction between ambitious and modest transcendental arguments, developed and deployed by various authors in the wake of Stroud’s influential critique of transcendental reasoning, may be pointless when applied to transcendental arguments from performative inconsistency that have moral statements as their conclusions. If moral truth is assertorically constrained, then any modest moral transcendental argument from performative inconsistency can be converted into an ambitious moral transcendental argument. The chapter provides an account of performative inconsistency and suggests an (...) alternative to the widespread reading of transcendental conditionals in terms of an ‘if-then’-sentences whose antecedents express a proposition to the effect that some x is possible and whose consequents express a statement to the effect that some y is actual. (shrink)

Evidential decision theory (EDT) says that the choiceworthiness of an option depends on its evidential connections to possible outcomes. Causal decision theory (CDT) holds that it depends on your beliefs about its causal connections. While Newcomb cases support CDT, Arif Ahmed has described examples that support EDT. A new account is needed to get all cases right. I argue that an option A's choiceworthiness is determined by the probability that a good outcome ensues at possible A‐worlds that match actuality in (...) the facts causally unaffected by your decision (the “unaffected facts”). Moreover, you should evaluate A on the assumption that A is compossible with the unaffected facts. This view entails that you should use EDT when evaluating A on the assumption that the unaffected facts determine your action, but use CDT when assessing A on the opposite assumption. A's choiceworthiness equals a weighted average of these conditional assessments. The weights are determined by your beliefs about whether the unaffected fact determine your action. This account gets both Newcomb and Ahmed cases right. According to an influential view, whether you take the unaffected facts to determine your action can make a difference to whether you can regard yourself as free and the action as being under your control. While my account is neutral on this issue, it entails that whether you take the unaffected facts to determine your action is important in a different way: it matters to whether you should follow EDT or CDT. (shrink)

The volume collects classics of Marxist historiography of science, including a new translation of Boris Hessen's “The Social and Economic Roots of Newton's ...

Bogolubov's classical example of statistical relaxation in a many-dimensional linear oscillator is discussed. The relation of the discovered relaxation mechanism to quantum dynamics as well as to some new problems in classical mechanics is considered.

In a wide-ranging 2007 study of Claude Lévi-Strauss's aesthetic thought, Boris Wiseman demonstrates not only its centrality within his oeuvre but also the importance of Levi-Strauss for contemporary aesthetic enquiry. Reconstructing the internal logic of Lévi-Strauss's thinking on aesthetics, and showing how anthropological and aesthetic ideas intertwine at the most elemental levels in the elaboration of his system of thought, Wiseman demonstrates that Lévi-Strauss's aesthetic theory forms an integral part of his approach to Amerindian masks, body decoration and mythology. (...) He reveals the significance of Lévi-Strauss's anthropological analysis of an 'untamed' mode of thinking at work in totemism, classification and myth-making for his conception of art and aesthetic experience. In this way, structural anthropology is shown to lead to ethnoaesthetics. Lévi-Strauss, Anthropology and Aesthetics adopts a broad-ranging approach that combines the different perspectives of anthropology, philosophy, aesthetic theory and literary criticism into an unusual and imaginative whole. (shrink)

Drawing from cognitive learning theories we hypothesize that exposure to nationalistic appeals that suggest consumers should shun foreign brands for moral reasons increases the general belief in consumers that buying foreign brands is morally wrong. In parallel, drawing from the theory of psychological reactance we posit that such appeals may, against their communication goal, increase the reputation of foreign luxury brands. We term the juxtaposition of these apparently contradictory effects the “Ambivalence Hypothesis.” Further, drawing from prior research on source-similarity effects (...) we posit that foreign luxury brands that communicate cultural proximity to target consumers (i.e., a local brand positioning) reinforce psychological reactance (“Clean Conscience Hypothesis”). We test these hypotheses experimentally in the context of luxury car brand advertising in China, a market that is heavily dominated by foreign brands, and therefore provides a breeding ground for ambivalent consumer reactions. Results show that exposure to nationalistic appeals enhances consumers’ national identity dispositions (patriotism, local identity), which results in higher levels of consumer ethnocentrism. Further, nationalistic appeals enhance the social responsibility associations that consumers hold for foreign luxury brands and their countries of origin, which results in a higher brand reputation. Finally, effects of nationalistic appeals on foreign luxury brand reputation are positively stronger for brands using a local vs. a foreign or a global positioning. These findings suggest that nationalistic appeals are a double-edged sword with important implications for ethics in political communication and luxury brand marketing. (shrink)

In this paper, we reflect on the connection between the notions of organism and organisation, with a specific interest in how this bears upon the issue of the reality of the organism. We do this by presenting the case of Buffon, who developed complex views about the relation between the notions of “organised” and “organic” matter. We argue that, contrary to what some interpreters have suggested, these notions are not orthogonal in his thought. Also, we argue that Buffon has a (...) view in which organisation is not just ubiquitous, but basic and fundamental in nature, and hence also fully natural. We suggest that he can hold this view because of his anti-mathematicism. Buffon’s case is interesting, in our view, because he can regard organisation, and organisms, as perfectly natural, and can admit their reality without invoking problematic supernaturalist views, and because he allows organisation and the organismal to come in kinds and degrees. Thus, his view tries to do justice to two cautionary notes for the debate on the reality of the organism: the need for a commitment to a broadly naturalist perspective, and the need to acknowledge the interesting features of organisms through which we make sense of them. (shrink)