Genome editing enables very accurate alterations to DNA. It promises profound and potentially disruptive changes in healthcare, agriculture, industry, and the environment. This paper presents a multidisciplinary analysis of the contemporary development of genome editing and the tension between continuity and change. It draws on the idea that actors involved in innovation are guided by “sociotechnical regimes” composed of practices, institutions, norms, and cultural beliefs. The analysis focuses on how genome editing is emerging in different domains and whether this marks (...) continuity or disruption of the established biotechnology regime. In conclusion, it will be argued that genome editing is best understood as a technology platform that is being powerfully shaped by this existing regime but is starting to disrupt the governance of biotechnology. In the longer term is it set to converge with other powerful technology platforms, which together will fundamentally transform the capacity to engineer life. (shrink)

The ethics of Du Pont's CFC strategy from 1975 to 1995 are analyzed using a Potter's Box framework. This approach includes an examination of relevant facts, prioritization of stakeholder loyalties, selection of a mode of ethical reasoning, and a world view. Du Pont's approach to ethical reasoning reflects changing facts and changing interpretation of the facts, a focus on shareholders as the primary and most important stakeholder, and ends-based reasoning, which views creating shareholder value as the primary end. An alternative (...) approach is proposed, based on analysis of Du Pont's and stakeholders' needs. (shrink)

Grace de Laguna was a philosopher working in the first part of the twentieth century on analytic and speculative philosophy, as well as on the psychology and philosophy of language, especially the social function of language. Joel Katzav’s lead essay focuses mainly on the former part of her work, while my commentary focuses mostly on the latter. Katzav shows how her work played a role in the development of analytic philosophy, I try to show how her work played a role (...) in the development of pragmatic linguistics, whose development overlapped with some aspects of analytic philosophy. I situate it in the context of an emerging ‘pragmatic Weltanschauung’ that was embraced by many working in linguistics, philology, philosophy, psychology, anthropology and what would later be called linguistic pragmatics. (shrink)

On 14 July 2021, the western states of Germany, Rheinland Palatinate and North-Rhein-Westphalia experienced major flash floods and about two hundred people died. This article explores how those affected and journalists they spoke to created meaning from the mayhem of an unprecedented disaster and how social representations of flooding emerged in which language, politics and values were intimately intertwined. Combining thematic analysis with elements of social representations theory, and analysing a sample of articles from a national news magazine, we show (...) how social representations of the floods were shaped by the objectification of the floods through metonymy (mud and debris) and the anchoring of the floods through personification and metaphors (natural and mechanical forces), thus adding a new dimension to the existing body of work on flood and metaphors. We claim that the immediate focus on the extreme force of the 2021 floods, on the one hand, and the weakness of political response, on the other, may entrench feelings of helplessness and divert attention away from more systematic and long-term engagement with flood dangers in the context of climate change, including extreme weather events. (shrink)

This paper aims to determine whether we can locate temporal passage in a non-dynamical (block universe) world. In particular, we seek to determine both whether temporal passage can be located somewhere in our world if it is non-dynamical, and also to home in on where in such a world temporal passage can be located, if it can be located anywhere. We investigate this question by seeking to determine, across three experiments, whether the folk concept of temporal passage can be satisfied (...) in our world if it is non-dynamical, and, if it can, what sort of thing in our world satisfies that concept. In particular, we focus on the question of whether that concept (if satisfied) is satisfied by something mind-dependent or something mind-independent. In other words, we ask, is temporal passage something that is at least partially in the mind, or is it entirely external to the mind? We find, contrary to what is often assumed by dynamists and non-dynamists alike, that the folk concept of temporal passage is satisfied in our world conditional on it being non-dynamical, and that the concept is satisfied by something mind-independent. This provides further ammunition for recent deflationary accounts of temporal passage that attempt to locate passage somewhere in our non-dynamical world. (shrink)

Zusammenfassung In Deutschland heimisch gewordene Hindus aus Südasien, die für ihre Götterverehrung bisher Räumlichkeiten in vorhandenen Gebäuden benutzten, haben begonnen, eigene Tempel zu errichten. Bisher wurden drei derartige Verehrungsstätten fertiggestellt, zwei weitere befinden sich im Bau. Die äußere Gestaltung orientiert sich in allen Fällen an traditionellen hinduistischen Sakralbauten, wie sie vor allem auf Sri Lanka und in Südindien begegnen. Dieser Stil zeichnet sich vor allem durch Aufbauten auf den Tempeldächern und über dem Eingang aus, an denen vielfältige Skulpturen göttlicher Wesen (...) angebracht sind. Gründe für die Entscheidung für solche aufwendigen und kostspieligen Projekte sind im Wunsch nach Gebäuden zu suchen, Bezüge zur ehemaligen Heimat herzustellen und eigene kunstvolle Baukunst zu demonstrieren. Sie speisen sich aber auch aus dem Bedürfnis, die Gottheiten in Gebäuden verehren zu können, die überkommenen hinduistischen Vorstellungen von sakralen und sakralisierbaren Götterbehausungen entsprechen. (shrink)

This book, first published in 2000, offers translations of the initial critical reactions to Kant's philosophy. Also included is a selection of writings by Kant's contemporaries who took on the task of defending the critical philosophy against early attacks. The first aim of this collection is to show in detail how Kant was understood and misunderstood by his contemporaries. The second aim is to reveal the sorts of arguments that Kant and his first disciples mounted in their defense of the (...) theoretical philosophy. The third aim of the book is to contribute to an understanding of the development of Kant's critical philosophy after its initial formulation in the Critique of Pure Reason, and in particular why Kant made the changes he did in the second edition of the work in 1787. This collection, which includes a glossary of key terms and biographical sketches of the critics on both sides of the debate, is a major addition to Kant scholarship and should be seen as a companion volume to the Cambridge Edition of the Works of Immanuel Kant. (shrink)

Spinal muscular atrophy (SMA) type 1 is a genetic neuromuscular disease in children that leads to degeneration of spinal cord motor neurons. This sometimes results in severe muscular paralysis requiring mechanical ventilation to sustain the child’s life. The onset of SMA type 1, the most severe form of the disease, is during the first year of life. These children become severely paralysed, but retain their intellectual capacity. Ethical concerns arise when mechanical ventilation becomes necessary for survival. When professionals assess the (...) resulting life for the child and family, they sometimes fear it will result in unreasonably excessive care. The aim of this article is to present an analysis of ethical arguments that could support or oppose the provision of invasive ventilation in this population. This examination is particularly relevant as France is one of the few countries performing tracheotomies and mechanical ventilation for this condition. (shrink)

Le travail avec les familles ayant une histoire en lien avec la migration nécessite une réflexion et une écoute adaptées. Dans ce contexte a été pensé un dispositif thérapeutique au sein d’un centre médico-psychopédagogique pour accueillir et prendre en compte l’origine culturelle ainsi que la situation transculturelle de ces familles. Cet article relate l’expérience clinique d’une mère et de son enfant autour de contes issus de la tradition orale du Maghreb dans le cadre d’un atelier rassemblant des dyades mères-enfants. Le (...) dispositif a pu restaurer le lien symbolique et dyadique, activer une autorisation à apprendre. La remobilisation des représentations culturelles au travers du conte a joué un rôle essentiel dans la renarcissisation à un niveau individuel pour une (re)construction identitaire. (shrink)

Reflexivity does not presuppose linguistic articulation or even propositional content. If it did, art could not be called reflexive. Reflexivity can be found in the self-contact of the living, in mental reflection or in symbolic self-reference. Art is a medium which claims these different modes of reflexivity and intertwines them. Aesthetic reflexivity as such has been established by Kant and his epigones, following the model of transcendetal reflection. Thus it could be specified as the reflexive structure of aesthetic judgement, or (...) as an emphasis on a work’s being created, or as a reference to perception itself in the process of perceiving, or as a way of reflecting concepts. Aesthetic reflexivity can only be detached from the model of transcendental reflection, if it is seen as oriented towards the interaction among the three modes of reflection mentioned above, leaving aside the difference, interplay or competition between perception and conceptual capacities. (shrink)

Walter Benjamin, der Traum und das Bild des Weiblichen Geschichtsphilosophie aus gendertheoretischer Perspektive. 0Karin Stögner: 0Beschädigtes Leben und antisemitische „Schiefheilung". Freud und Adorno revisited.0Ljiljana Radonic: 0Autonomie versus Engagement? Über Adorno und Brecht. 0Gerhard Scheit: 0„Une promesse de bonheur". Herbert Marcuses „Über den affirmativen Charakter der Kultur".0Daniela Berner und Florian Wagner: 0Gebrochene Geschichte, Bedrängte Gegenwart. Möglichkeiten und Grenzen eines fremdgestellten Blicks 0auf die nationalsozialistische Vergangenheit im Film. 0Tobias Ebbrecht-Hartmann: 0Das drastische Medium. Über Adornos Kritik des Films. 0Christoph Hesse: 0Träumerinnen im Wachen. (...) Die „Kollektivträume" der Comics und die Kritische Theorie. 0Barbara Eder : 0Verehrte Unsichtbare!"0Über die Kunst des Hörens bei Walter Benjamin und Theodor W. Adorno 0Christine Ehardt: 0Exkursion 0Shopping Mall, mit Walter Benjamin u.a. 0Anette Baldauf : 0Zum Einbruch des.Realen' in die Gegenwart 0Eingedenken, Erinnern, Katharsis 0Sara Vorwalder und Veronika Zangl : 0„Alles wirklich Brauchbare besteht in Aushilfen". Zwei Lektüren zu Oskar Negt und Alexander Kluges Geschichte und Eigensinn 0Valentin Mertes und Michael Paninski : 0„Die Nord-West-Passage der Revolution" 0Herrschaftsverhältnisse und die situationistische Kartographierung 0der Stadtlandschaft 0Brigitte Marschall: 0. (shrink)

Despite the scientific revolutions of the twentieth century, mechanistic explanations show a striking methodological continuity from early modern science to current scientific practice. They are rooted in the traditional method of analysis and synthesis, which was the background of Galileo’s resolutive-compositive method and Newton’s method of deduction from the phenomena. In early modern science as well as in current scientific practice, analysis aims at tracking back from the phenomena to the principles, i.e., from wholes to parts, and from effects to (...) causes. Vice versa, synthesis aims at explaining the phenomena from the parts and their interactions. Today, mechanistic explanations are atomistic in a generalized sense. They have in common to explain higher-level phenomena in terms of lower-level components and their causal actions or activities. In quantum physics, the lower-level components are subatomic particles, and the causes are their quantum interactions. After the quantum revolution, the approach continues to work in terms of the sum rules which hold for conserved properties of the parts and the whole. My paper focuses on the successes and limitations of this approach, with a side glance at the recent generalization of mechanistic explanations in cognitive neuroscience. (shrink)

Im Dezember 2014 fand das erste zweitatige Symposium von der SWIP (Society of Women In Philosophy) Austria statt, unter dem Titel: Neuere Aspekte in der Philosophie - aktuelle Projekte von Philosophinnen am Forschungsstandort Osterreich." Als Resultat dieser Tagung soll der vorliegende Band die Breite und Pluralitat der Themen und die Themenoffenheit widerspiegeln. Er enthalt 22 Beitrage aus den verschiedensten Teildisziplinen der Philosophie, wie feministische Sprachphilosophie, Performance/Philosophie, Erkenntnis- und Wissenschaftstheorie, Wissenschaftsgeschichte, philosophische Bezugnahme auf Literatur, feministisch-philosophische Literaturbetrachtung, praktische Philosophie, Religion und Ethik, (...) interkulturelle Philosophie, feministisch-politische Theorie, feministische Sozialphilosophie und queere Perspektiven.". (shrink)

Welche Erkenntnisse bietet Michel Foucaults Ansatz der Gouvernementalität für eine politische Theorie, die Geschlecht als zentrale Kategorie setzt? In diesem Band werden Grundbegriffe aus Foucaults Spätwerk aus feministischer Sicht beleuchtet, z.B. Gouvernementalität, Macht, Staat, Subjekt, Sicherheit, Wissen und Kritik. Diese Re-Lektüre möchte zum einen Foucaults Ansatz geschlechtertheoretisch weiterentwickeln und vertiefen, zum anderen Anstöße für eine politische Theoretisierung von Geschlecht geben.

The impact of social media influencers (SMIs) on brand-related outcomes has been well researched, yet whether this influence also impacts political participation and what role the relationship between SMIs and their audiences play has not been sufficiently examined to date. Basing this study on the Balance Model, I investigated the potential of an unlikely vs. a likely source and the role of similarity with a SMI based on a shared topic interest to elicit the intention for political action in an (...) experimental study (n = 222). The perceived similarity with the SMI was examined as a mediator and the role of the shared topic interest with the SMI as a potential moderator. The results indicate that a likely source for political information generated a greater topic fit. The perceived similarity with the source depended on the shared topic interest between the source and the participants. This is a key finding, as perceived similarity with the source in turn predicted the intention to take political action, which positively activated participants who shared the topic interest of the unlikely source even if they did not indicate a topic interest in politics. Thus, a shared interest with a SMI might make even those not interested in politics more open to political participation. (shrink)

This book analyzes--in terms of branching--the pervasive reorganization of Latin syntactic and morphological structures: in the development from Latin to French, a shift can be observed from the archaic, left-branching structures (which Latin inherited from Proto-Indo-European) to modern right-branching equivalents. Brigitte Bauer presents a detailed analysis of this development based on the theoretical discussion and definition of "branching" and "head." Subsequently she relates the diachronic shift to psycholinguistic evidence, arguing that the difficuly of LB complex structures as reflected in (...) their painstaking and delayed acquisition accounts for the extensive typological shift from left to right branching that took place in Latin/French and the other Indo-European languages. (shrink)

This article adds to earlier research revealing that the American news media did not discharge their responsibility as a watchdog press in the post-9/11 years by failing to scrutinize extreme and unlawful government policies and actions, most of all the decision to invade Iraq based on false information about Saddam Hussein’s alleged weapons of mass destruction arsenal. The content analyses presented here demonstrate that leading US news organizations, both television and print, did not expressly refer to human rights violations when (...) they reported on the torturing of foreign detainees during “enhanced interrogations” in US-run prison facilities abroad and the killing of civilians, including children, in US drone strikes overseas and outside theaters of war. Moreover, by framing torture and the “collateral damage” caused by drone-launched missile attacks episodically rather than in the context of human rights, the news media failed to alert the American public to the grave humanitarian violations in the so-called war on terrorism during the George W. Bush and Barack Obama administrations. (shrink)

Outil de « réflexion massive » dans le monde universitaire Outre-Manche et Outre-Atlantique depuis quelques décennies et le texte majeur de Joan Scott, le Genre n'est que récemment et partiellement entré dans l'université française et la recherche où il continue de déranger tout en s’institutionnalisant. Plutôt que tracer une chronologie déjà élaborée par d'autres, cet article propose une réflexion autour de deux expériences directement liées à ce numéro : la pratique du Genre au sein du CHCSC et les précédentes publications (...) de Diogène sur le sujet. (shrink)

This paper deals with some structural properties of the sequent calculus and describes strong symmetries between cut-free derivations and derivations, which do not make use of identity axioms. Both of them are discussed from a semantic and syntactic point of view. Identity axioms and cuts are closely related to the treatment of negation in the sequent calculus, so the results of this article explain some nice symmetries of negation.

After the UN Guiding Principles on Business and Human Rights were adopted in 2011, an international treaty has been being negotiated since 2014. The two instruments reveal similarities and also conflicts regarding the adequate organization of the global economy based on human rights. The focus in this article will be on the processes leading to these instruments, because they themselves mirror different understandings of governance in the field of business and human rights as well as the struggle over the power (...) of definition and legitimacy. The UNGPs were developed on the basis of global multi-stakeholder consultations, underlining legitimacy through broad inclusion. There are varying judgements as to the success of this approach. The process towards the treaty follows the traditional path of negotiations at UN level. These negotiations reveal a struggle for recognition of the legitimacy of the process itself. Both procedures have shortcomings with regard to legitimacy and show the need for a revision concerning the inclusion of stakeholders. The complementarity of a soft and hard law instrument may enhance the creation of a level playing field in the global economy, thereby strengthening human rights. (shrink)

As well known, the exact sciences served Kant as a model of metaphysical cognition. There is also an opposite relation between science and metaphysics, however, namely the teleology of reason, as expressed at the end of the Critique of Pure Reason. There, Kant claims that the sciences are ultimately subordinate to the essential ends of humanity “through the mediation of a rational cognition from mere concepts”, i. e., metaphysical cognition.

The paper presents a logical treatment of actions based on dynamic logic. This approach makes it possible to reflect clearly the differences between static and dynamic elements of the world, a distinction which seems crucial to us for a representation of actions.Starting from propositional dynamic logic a formal system (DLA) is developed, the programs of which are used to model action types. Some special features of this system are: Basic aspects of time are incorporated in DLA as far as they (...) are needed for our purpose. Names for states and for instants are simulated by formulas. It is possible to express formally that a formula is satisfiable or valid. A special program is introduced to reflect developments which are not caused by an official agent but by external influences. (shrink)

Extremists often aim to paint a biased picture of the world. Radical narratives, for instance, in forms of internet memes or posts, could thus potentially trigger cognitive biases in their users. These cognitive biases, in turn, might shape the users’ formation of extremist attitudes. To test this association, an online experiment (N=392) was conducted with three types of right-wing radical narratives (elite-critique, ingroup-outgroup, violence) in contrast to two control conditions (nonpolitical and neutral political control condition). We then measured the impact (...) of these narratives on the activation of three cognitive biases of relevance in the formation of extremist attitudes: the ingroup-outgroup bias, the negativity bias, and the just-world hypothesis. The results indicate that violence narratives seem to be particularly harmful as they heighten participants’ negativity bias and increase just-world views. Just-world views in turn show a positive relationship to extremist attitudes, which highlights the need of regulating violence invocations on social media. (shrink)

This is the first day of our confinement here in Paris, which soon will feel a bit like house arrest. So, to help cheer you up, in these times of doom and gloom, I have decided to bring the museum to you in the form of a virtual exhibition thrice weekly. I have picked 25 photos from a work in progress I started years ago. The photos are portraits of visitors or guards in museums. It's candid photography, capturing life on (...) the run, a moment in time. I hope you will find many other ways to - Résidence numérique - Brigitte Cavanagh. (shrink)

Comment le concept de genre s’est-il implanté à l’Est, dans les pays de l’ancienne aire d’influence soviétique après la chute du Mur? C’est à cette question innovante que s’attelle Ioana Cîrstocea dans son habilitation à diriger des recherches, remaniée pour en faire cet ouvrage au beau titre — référence à l’écrivaine et journaliste biélorusse Svetlana Alexievitch, Prix Nobel de littérature. S’il est aujourd’hui communément admis dans les sciences humaines et sociales que les idées, les réfé...

In 2019 a novel coronavirus, SARS-CoV-2, spread around the world and a global pandemic was declared early in 2020. Currently, the pandemic has still not been brought under control. Over time, many new words have seeped into ordinary language and old words have changed their meanings. In this article, I trace the semantic development of the word ‘endemic’ which spread from science discourse into political discourse and then into public discourse and became a euphemism. People are told that they should (...) now ‘live with’ the pandemic, a pandemic that is no longer dangerous, because it has turned endemic. This euphemistic use of ‘endemic’ has serious consequences for pandemic management and disease control, not only in countries like the UK, where the word has, indeed, become ‘endemic’, but around the world, as the word has the social function of concealing the circulation of the virus and normalising the spread of infection, even death. (shrink)