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Nanomaterials have attracted much interest in the medical field and related applications as their distinct properties in the nanorange enable new and improved diagnosis and therapies. Owing to these properties and their potential interactions with the human body and the environment, the impact of nanomaterials on humans and their potential toxicity have been regarded a very significant issue. Consequently, nanomaterials are the subject of a wide range of cutting-edge research efforts in the medical and related fields to thoroughly probe their (...) potential beneficial utilizations and their more negative effects. We posit that the lack of standardization in the field is a serious shortcoming as it has led to the establishment of methods and results that do not ensure sufficient consistency and thus in our view can possibly result in research outputs that are not as robust as they should be. The main aim of this article is to present how NanoDiaRA, a large FP7 European multidisciplinary project that seeks to investigate and develop nanotechnology-based diagnostic systems, has developed and implemented robust, standardized methods to support research practices involving the engineering and manipulation of nanomaterials. First, to contextualize this research, an overview of the measures defined by different regulatory bodies concerning nanosafety is presented. Although these authorities have been very active in the past several years, many questions remain unanswered in our view. Second, a number of national and international projects that attempted to ensure more reliable exchanges of methods and results are discussed. However, the frequent lack of publication of procedures and protocols in research can often be a hindrance for sharing those good practices. Subsequently, the efforts made through NanoDiaRA to introduce standardized methods and techniques to support the development and utilization of nanomaterials are discussed in depth. A series of semi-structured interviews were conducted with the partners of this project, and the interviews were analyzed thematically to highlight the determined efforts of the researchers to standardize their methods. Finally, some recommendations are made toward the setting up of well-defined methods to support the high-quality work of collaborative nanoparticle-based research and development projects and to enhance standardization processes. (shrink)

The article discusses research work of Heinrich Hofmann, who has completed doctoral studies in mathematics under Karl Weierstrass in Berlin. His first book "Philosophy of Arithmetic: Psychological and Logical Investigations With Supplementary Texts From 1887-1901" contains his thesis "In the Concept of Number: Psychological Analyses" completed in the guidance of Weierstrass.

The book presents a thoroughly elaborated logical theory of generalized truth-values understood as subsets of some established set of truth values. After elucidating the importance of the very notion of a truth value in logic and philosophy, we examine some possible ways of generalizing this notion. The useful four-valued logic of first-degree entailment by Nuel Belnap and the notion of a bilattice constitute the basis for further generalizations. By doing so we elaborate the idea of a multilattice, and most notably, (...) a trilattice of truth values – a specific algebraic structure with information ordering and two distinct logical orderings, one for truth and another for falsity. Each logical order not only induces its own logical vocabulary, but determines also its own entailment relation. We consider both semantic and syntactic ways of formalizing these relations and construct various logical calculi. (shrink)

Betr. u.a. die letzten Briefe Friedrich Nietzsches an Jacob Burckhardt.

Das Gemeinwohl ist Gegenstand, aber auch Bedingung politischer Auseinandersetzungen. Daher ist eine reflexiver Politik gefordert, die ihr Selbstverständnis auf der Basis einer Gemeinwohlkonzeption definiert. Der Autor thematisiert die theoretischen Grundlagen einer gemeinwohlorientierten Politik und veranschaulicht diese anhand von Beispielen.

Das Handlexikon zur KrV gibt verläßliche und unentbehrliche Orientierungshilfen für die systematische Auseinandersetzung mit Kants epochalem Hauptwerk. Es kann für alle Ausgaben, die den Seitenumbruch der ersten und zweiten Auflage (A 1781, B 1787) im Text kennzeichnen, herangezogen werden.

Teilband 1. Einleitung des "Naturrechts Feyerabend" -- Teilband 2. Abhandlung des "Naturrechts Feyerabend" : Text und Hauptindex -- Teilband 3. Abhandlung des "Naturrechts Feyerabend" : Konkordanz und Sonderindices.

Dieser Band geht der Frage nach, welches Interesse Platon und seine Lehren in der Zeit des Hellenismus ausserhalb der Akademie fanden. Die kommentierten Zeugnisse berichten uber Kritik und Lob, Ablehnung und Anerkennung Platons, die ersten Bemuhungen antiker Grammatiker um das Corpus Platonicum sowie die Bestrebungen, in Platon (wie in Pythagoras) einen Verkunder ostlicher Weisheit zu sehen.'Ein wirkliches Jahrhundertwerk deutscher altertumswissenschaftlicher Forschung.' Christoph Markschies, Zeitschrift fur Kirchengeschichte.