The present piece focuses on the influence of Plotinus' understanding of time and eternity as articulated in Plotinus' third and fifth Enneads upon Mīr Dāmād's (d. 1631–2) conception of eternity, perpetuity, and time found in his Book of Blazing Brands (Kitab al‐Qabasāt). Although Mīr Dāmād's conception of eternity, perpetuity, and time resembles that of Plotinus' cosmology and ontology, he departs from Plotinus' hypostases in establishing strict parameters for each domain. Unlike Plotinus, Mīr Dāmād argues that the realm of eternity is (...) reserved for God alone, while the realm of Perpetuity contains the Platonic Forms. For Mīr Dāmād, the realm of time is an effect of the realm of Perpetuity and a tool for human beings to understand how to measure events in the temporal world. Unlike many other Shī'ite philosophers, Mīr Dāmād's articulation of these three cosmological realms incorporates thought found in the works of both prominent Sunni and Shī'ite scholars such as Ibn Sīnā, Abū Ḥāmid al‐Ghāzālī, Suhrawardī, and Naṣīr al‐Dīn Ṭūsī. Although his most successful student, Mullā Ṣadrā Shirazī, had ultimately disagreed with his teacher's cosmological doctrine, he remained influenced by the multitude of sources that his teacher had used. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Philosophy, Psychiatry, & Psychology 9.2 (2002) 159-160 [Access article in PDF] The Nine Lives of the Dynamic Unconscious Jerome Kroll IN THEIR PROVOCATIVE ARTICLE "Dispensing with the Dynamic Unconscious," O'Brien and Jureidini offer two basic arguments against the existence or, more accurately, because we are dealing here with constructs, the plausibility, of the dynamic unconscious. First, they assert, in contradistinction to the psychoanalytic claim that evidence of a (...) cognitive unconscious supports the claim for a dynamic unconscious, that the notion of a cognitive unconscious is incompatible with that of a dynamic unconscious. Second, they argue on the grounds of parsimony that the phenomena explained by a dynamic unconscious can be better explained (accounted for) by other mechanisms.I would argue that neither of their contentions is correct. O'Brien and Jureidini have essentially taken data and evidence from cognitive science, issued a new vocabulary, and then asserted that their vocabulary is superior and constitutes better explanations for the phenomena and observations under question. They have failed to show any incompatibility between the two explanatory constructs. O'Brien and Jureidini agree with the basic Freudian tenet that most mental activity is unconscious, that is, out of consciousness, and that much of what is out of consciousness can be brought into consciousness with proper cueing. No problem so far.The problem with the dynamic unconscious, as O'Brien and Jureidini see it, is that the cognitive unconscious is modular, best described as a series of subpersonal systems akin to a set of narrowly focused computational specialists, whereas the dynamic unconscious contains fully formed repressed memories. What O'Brien and Jureidini have now given us are multiple homunculi rather than just one CEO or executive homunculus. How literally do we want to take these subpersons? Are subpersonal mental states more satisfactory scientifically than personal-level mental states? Second, O'Brien and Jureidini unfairly attribute to the psychoanalytic position the claim that the dynamic unconscious "is presumed to contain fully formed repressed memories." With the compelling evidence from psychology and neuroscience that all memory is a reconstruction, I do not think that any contemporary psychodynamicist makes a case for fully formed repressed memories, nor is this notion essential to a theory of a dynamic unconscious. O'Brien and Jureidini invoke Occam's razor by invoking a straw horse argument. Their description of the action of subpersonal parts doing sufficient specific cuing sounds suspiciously like the work done in the dynamic unconscious. In the next section, an emotional response is described as pushing images out of mind before they can be reported on (assumedly, before they become conscious). What is doing the pushing here? Upon what principles or priorities are images pushed out of mind?The authors explain that mental "representations are inaccessible to consciousness by virtue [End Page 159] of architectural constraints rather than the operation of a repressive force." But architectural constraints sounds like another way of describing neural facilitation and inhibition. Certainly most neural activity, perhaps all, involves facilitation and inhibition of signals at multiple synapses. Repression is just a psychological construct to describe what the processes of facilitation and inhibition bring about in terms of meaningful mental activity. While we are on the topic of choice of words, the repeated description of the dynamic unconscious as subterranean is an inflammatory locution designed to rally opposition to the notion. The cognitive unconscious is equally subterranean.To look further into the supposed superiority of explanation via the cognitive unconscious, we see that O'Brien and Jureidini attribute the following processes to the cognitive unconscious: evaluation, decision making, editing out, filling in, reconstruction, and reconfiguration. But what are the bases of these processes? What guides or influences the way ideas, images, and emotions are reconstructed and reconfigured? It does not appear to be done randomly. When the reconstructive narrative becomes "significantly distorted" because the memory to be retrieved is fraught with distress, what accounts for the shape of the distortion and what (dare we say who?) recognizes that a memory is about to be distressing? We may all be unhappy with the notion of a dynamic unconscious... (shrink)

In this manuscript we describe Proteogenomics Viewer, a web‐based tool that collects MS peptide identification, indexes to genomic sequence and structure, assigns exon usage, reports the identified protein isoforms with genomic alignments and, most importantly, allows the inspection of MS2 information for proper peptide identification. It also provides all performed indexing to facilitate global analysis of the data. The relevance of such tool is that there has been an increase in the number of proteogenomic efforts to improve the annotation of (...) both genomics and proteomics data, culminating with the release of the two human proteome drafts. It is now clear that mass spectrometry‐based peptide identification of uncharacterized sequences, such as those resulting from unpredicted exon joints or non‐coding regions, is still prone to a higher than expected false discovery rate. Therefore, proper visualization of the raw data and the corresponding genome alignments are fundamental for further data validation and interpretation. (shrink)

How is language acquired when infants are exposed to multiple language input from birth and when adults are required to learn a second language after early childhood? How do adult bilinguals comprehend and produce words and sentences when their two languages are potentially always active and in competition with one another? What are the neural mechanisms that underlie proficient bilingualism? What are the general consequences of bilingualism for cognition and for language and thought? This handbook will be essential reading for (...) cognitive psychologists, linguists, applied linguists, and educators who wish to better understand the cognitive basis of bilingualism and the logic of experimental and formal approaches to language science. (shrink)

Die Gerechtigkeit erfährt bei Meister Eckhart einen prägenden Stellenwert: er spricht von einem «underscheit» zwischen Gerechtigkeit und Gerechtem. Ausgehend von diesem «underscheit» postuliert die Studie eine dialektische Struktur, die inhaltlich als un-aufhebbar bestimmt wird. Mit Eckharts Leitvers «die Gerechten werden leben ewiglich bei Gott» wird im thetischen Begriff «die Gerechten» epistemologisch, ontologisch und theologisch Eckharts univok-deduktives Denken, im antithetischen «werden leben» der Werk-Begriff unter analog-induktiver Perspektive gezeigt, der synthetische «ewiglich bei Gott» etabliert grundlegend den «underscheit» von Gerechtigkeit und Gerechtem als (...) un-aufhebbare Dialektik. Im «underscheit» liegt hermeneutische Offenheit und Aktualität der Predigt Meister Eckharts. (shrink)

During periods of scarcity, or the fear of it, many health systems create or adopt triage protocols to determine how to best allocate limited resources. Interest in such protocols has become acute...

COVID-19 vaccine research success and emergency use authorizations have shown the life sciences’ potential for positive health impact. But they also underscore potentially divergent and conf...

1. Littérature et insignifiance -- 2. Linguistique et insignifiance -- 3. Art et insignifiance.

Background Few studies have been conducted to assess the quality of orientation practices for ethics advisory committees that conduct ethics consultation. This survey study focused on several Harvard teaching hospitals, exploring orientation quality and committee members’ self-evaluation in the American Society of Bioethics and Humanities ethics consultation competencies. Methods We conducted a survey study that involved 116 members and 16 chairs of ethics advisory committees, respectively. Predictor variables included professional demographics, duration on committees and level of training. Outcome variables included (...) familiarity with and preparedness in the ASBH competencies and satisfaction with orientations. We hypothesised that responses would be associated with both the aforementioned predictors and whether or not participants had encountered the ASBH competencies in training. Results A majority of respondents found their orientation curricula to be helpful, although a significant portion of respondents did not receive any orientation or were unsatisfied with their orientation. Familiarity with ASBH competencies was a statistically significant predictor of respondents’ self-evaluation in particular categories. Standard educational materials were reported as offered during orientation, such as readings and case studies ; different medium resources were less evidenced such as videos on ethics consultation. Conclusions Institutions should re-evaluate orientation practices for ethics committee members that perform ethics consultation. Integrating ASBH competencies and useful methods into a resourceful pedagogy will help improve both member satisfaction with orientation and preparation in consultation. (shrink)

Three ethical conflicts in particular are paradigmatic of what we define as “clerkship ethics.” First, a distinction that differentiates the clerkship student from the practicing physician involves the student’s principal role as a learner. The clerkship student must skillfully balance her commitment to her own education against her commitment to patient care in a fashion that may compromise patient care. While the practicing physician can often resolve the tension between these two goods when they come into conflict, the clerkship student (...) is left with a more ambiguous set of choices. Second, evaluative scrutiny during clinical clerkships often forces medical students to balance doing what is morally fitting against the perceived expectations of the medical teams in which they work. Third and finally, a deeply entrenched culture of medical hierarchy presents a particular challenge to innovation and improvement in ethics education during the clerkship years. Students regard faculty as exemplars, but are not provided with the tools to assess when technical medical competence is not matched by moral competence; moreover, these faculty are unlikely to have experienced the ethics education in which students are asked to demonstrate mastery. (shrink)

This book discloses a largely unnoticed dialogue between Muslim and Western social thought on the search for meaning and transcendence in the human sciences. The disclosure is accomplished by a comparative reading of contemporary Muslim debates on secular knowledge on the one hand, and of a foundational Western debate on the demise of metaphysics in the human sciences on the other hand. The comparative reading is grounded in a dialogical hermeneutic approach; that is, a hermeneutic approach to texts and cultural (...) traditions that draws upon the work of Hans Georg Gadamer and also upon the insights of inter-religious dialogue. (shrink)

In February 2016, the Cleveland Clinic initiated the first attempt at cadaveric uterine transplantation (UTx) in the United States. The transplantation was ultimately unsuccessful, but it opened doors for further research on both live and cadaveric UTx. While initial strides toward successful transplantation have been made, questions persist on the ethics of UTx: whether the uterus is a vital organ, whether we should prioritize live or cadaveric options, and how the procedure should be covered by health insurance. If we agree (...) that the goal of the medical profession is both to treat and improve quality of life, then the question of whether or not infertility is considered a disease becomes inconsequential in the discussion. As such, the medical enterprise should move forward with research in UTx. In doing so, considering the ethical implications of UTx remains essential—and we must remember to pair innovation with regulation. (shrink)

This paper examines the theoretical background and actual behavior in a gaming tournament with endogenous timing where a person has more incentive, structure, and time to form a strategy. The baseline treatment suggests that subgame perfection is a reasonable predictor of behavior –- subjects made 170 of 208 theoretically predicted choices of best actions, with the majority of mistakes made in timing choices by the players who did not survive the cut to the second round. Four sensitivity treatments established that (...) the design feature that lead to more predictable behavior was time to think –- 745 of 960 correctly predicted decisions with more time versus 595 of 960 with less time. A random effects Probit model suggests that the key design feature that closed the gap between predicted and observed behavior was not necessarily the non-linear payoffs created by the tournament design, but rather that the key was providing people with more time to think about their strategy. (shrink)

Ziel des PVS Sonderheftes ist es, die seit einiger Zeit boomende Konjunktur des Verantwortungsbegriffs zu reflektieren, die Relevanz dieses Begriffes zu analysieren und seinen Wandel angesichts gesellschaftlicher und technischer Veranderungen zu erfassen. Eines der wichtigsten Kriterien zur Beurteilung politischer Entscheidungen ist deren Verantwortlichkeit. Der Begriff der Verantwortung bezieht sich auf einen Rahmen normativer Erwartungen, die je nach Politikfeld starker rechtlich oder moralisch ausgepragt sind. Verantwortung bedeutet insbesondere, einem Akteur die Folgen seines Handels zuschreiben zu konnen. Ein Kernproblem aktueller Verantwortungskonzeptionen besteht (...) in der Diffusion von Verantwortung. Einerseits sind immer mehr Akteure an immer mehr Handlungszusammenhangen beteiligt, aber gleichzeitig sind immer weniger Akteure fur ihre Handlungsfolgen allein verantwortlich. Die Beitrage des Heftes diskutieren die Folgen dieser Dilemmata sowohl in ihren theoretischen Konsequenzen als auch empirisch anhand verschiedener Felder lokaler, nationaler und internationaler Politik. Der Band versammelt Expertinnen und Experten aus unterschiedlichen Disziplinen: von der Politikwissenschaft uber die Rechtswissenschaft bis hin zur Soziologie und Philosophie. (shrink)

The notion of singular (or de re) thought has become central in philosophy of mind and language, yet there is still little consensus concerning the best way to think about the nature of singular thought. Coinciding with recognition of the need for more clarity about the notion, there has been a surge of interest in the concept of a mental file as a way to understand what is distinctive about singular thought. What isn't always clear, however, is what mental files (...) are meant to be, and why we should believe that thoughts that employ them are singular as opposed to descriptive. This volume brings together original chapters by leading scholars which aim to examine and evaluate the viability of the mental files framework for theorizing about singular thought. (shrink)

This research aspires to represent the subversion of pre-defined gender roles in the novels; The Shadow of the Crescent Moon by Fatima Bhutto, Butterfly Season by Natasha Ahmed, and Stained by Abda Khan. The researchers aim to depict the destabilization of gender-based stereotyped identity from the Pakistani perspective. The selected method of study is Feminist Analysis by Tyson, which examines literature as a medium to represent feminist issues, whereas; the theoretical angle of “Matrix of Domination” from Collins’ Feminist/Gender theory is (...) used as a principle to analyze and depict the subversion of pre-defined gender roles in the selected novels. This study aims to establish the notion of gender as a social construct that could be subverted through literary discourses that have the potential to challenge the power-based gender roles within a patriarchal society. In this regard, different critical works of prominent theorists and writers have been discussed briefly in the literature review to project the significance of the works by contemporary Pakistani women writers as a medium to subvert identities formed by their society. Gender is also a means of power through which the dominant seeks to control the subordinate. The objective of this research is to suggest that gender is socially constructed, therefore, it can be deconstructed through literature. The selected novels exemplify the current gender inclinations of today’s Pakistan with the pen of female writers. Stereotyped gender identity is a socially constructed vice that divides humans into segments, hence it is required of the contemporary discourses to decenter such power discourses that perpetuate hegemonic boundaries and restrict the women into social shackles of imposed identities. (shrink)

This paper examines the contest between Canadian American industrialist Cyrus Eaton and the Pugwash scientists’ leadership for influence over the early Pugwash scientists’ conferences. Eaton's activism has generally been dismissed in the historical literature as ineffective, naive and too uncritical of the Soviet Union. This paper argues that he was genuinely committed to international peace and security, that Eaton shared with Pugwash scientists a belief in the importance of intellectuals to global unity, and that he worked to bring about greater (...) international peace and understanding through both his personal activism and his own conferences held in the town of Pugwash. Eaton, however, favoured a broader push for peace, which included participation by a wider range of intellectuals and a call for rapprochement with the Soviet Union. These differences between Eaton and the Pugwash scientists, I argue, were more than simply about approach: they represented different internationalist visions and manifested in different conceptualizations for the Pugwash scientists’ conferences. Eaton hoped to incorporate non-scientists and humanism into the conferences, and integrate them into his own broader conference programme at his Thinkers’ Lodge at Pugwash. The scientists, however, wanted to keep their conferences as distinctly scientists’ events, tied to science and its authority. (shrink)

This study is based on Post-cyberpunk in order to highlight the prominence of Postcyberpunk as an emerging representative genre of Postmodern Literature. Technological progress has altered the ontology of being a human in an era of information technology, thus this study aims to critically discuss the issues of id entity and representation. Although ample critical work has been done on genre Postcyberpunk yet this study is unique in a way that it is a collection of different discursive practices related to (...) identity crises presented in selected Post-cyberpunk narratives. It targets to critically analyze the alternations and transformations in representation of identity in the backdrop of Postmodernist Deconstruction of Metanarratives by Lyotard. Apart from the deconstruction of metanarratives this study signifies the relevance of Post-cyberpunk as Postmodernist Literature that represents society through multidimensional discursivity such as capitalism, hypercasaulization, imperialism, religion, economy and technology. This study aims to deconstruct the metanarratives of identity that were considered to be permanent and claimed to be power narratives. It equally represents the deconstruction of center/margin dichotomy by bringing mininarratives into the center. The method adopted for research is SocioCognitve Approach by van Dijk from Critical Discourse Analysis. (shrink)

As face shields are dusted off and conferences go virtual again, Omicron reminds us how the once-novel coronavirus ruptured our collective idea of medical training. For nearly 2 years, social media...

In 2012, Loyola University Chicago's Stritch School of Medicine became the first medical school in the United States to actively recruit and accept undocumented immigrants who received protections granted under the Deferred Action for Childhood Arrivals program that was established by presidential memorandum. By 2016, sixty-one medical schools were considering applications from DACA recipients for admission, and more than 110 students applied. According to the Association of American Medical Colleges, sixty-five DACA recipients matriculated in U.S. medical schools in the 2016–2017 (...) school year. These students contribute both diversity and talent to our medical community; they could also have a significant impact on the care of underserved and immigrant populations. The recent decision by the Trump administration to rescind DACA therefore comes with serious pragmatic and ethical ramifications, impeding our medical community's efforts to develop a diverse and representative workforce committed to improving access to quality care for all patients. (shrink)

What is difficult to imagine is also surprising to perceive. This indicates that active visual imagery is an integral part of active visual perception. Erroneous mental transformations provide clues to prior assumptions in visual imagery, just as visual illusions provide clues to perceptual assumptions. Visual imagery and perception share generic assumptions about invariants in images of rigid objects.