Cytoplasmic messenger ribonucleoprotein particles (mRNPs) represent the cellular transcriptome, and recent data have challenged our current understanding of their architecture, transport, and complexity before translation. Pre‐translational mRNPs are composed of a single transcript, whereas P‐bodies and stress granules are condensates. Both pre‐translational mRNPs and actively translating mRNPs seem to adopt a linear rather than a closed‐loop configuration. Moreover, assembly of pre‐translational mRNPs in physical RNA regulons is an unlikely event, and co‐regulated translation may occur locally following extracellular cues. We envisage (...) a stochastic mRNP transport mechanism where translational repression of single mRNPs—in combination with microtubule‐mediated cytoplasmic streaming and docking events—are prerequisites for local translation, rather than direct transport. (shrink)

The “language-communication-society” triangle defies traditional scientific approaches. Rather, it is a phenomenon that calls for an integration of complex, transdisciplinary perspectives, if we are to make any progress in understanding how it works. The highly diverse agents in play are not merely cognitive and/or cultural, but also emotional and behavioural in their specificity. Indeed, the effort may require building a theoretical and methodological body of knowledge that can effectively convey the characteristic properties of phenomena in human terms. New complexity approaches (...) allow us to rethink our limited and mechanistic images of human societies and create more appropriate emo-cognitive dynamic and holistic models. We have to enter into dialogue with the complexity views coming out of other more ‘material’ sciences, but we also need to take steps in the linguistic and psycho-sociological fields towards creating perspectives and concepts better fitted to human characteristics. Our understanding of complexity is different – but not opposed – to the one that is more commonly found in texts written by people working in physics or computer science, for example. The goal of this book is to extend the knowledge of these other more ‘human’ or socially oriented perspectives on complexity, taking account of the language and communication singularities of human agents in society. (shrink)

This book offers insights on the study of natural language as a complex adaptive system. It discusses a new way to tackle the problem of language modeling, and provides clues on how the close relation between natural language and some biological structures can be very fruitful for science. The book examines the theoretical framework and then applies its main principles to various areas of linguistics. It discusses applications in language contact, language change, diachronic linguistics, and the potential enhancement of classical (...) approaches to historical linguistics by means of new methodologies used in physics, biology, and agent systems theory. It shows how studying language evolution and change using computational simulations enables to integrate social structures in the evolution of language, and how this can give rise to a new way to approach sociolinguistics. Finally, it explores applications for discourse analysis, semantics and cognition. (shrink)

People generally accept that there is causation by omission—that the omission of some events cause some related events. But this acceptance elicits the selection problem, or the difficulty of explaining the selection of a particular omissive cause or class of causes from the causal conditions. Some theorists contend that dependence theories of causation cannot resolve this problem. In this paper, we argue that the appeal to norms adequately resolves the selection problem for dependence theories, and we provide novel experimental evidence (...) for it. (shrink)

The Midewiwin is the traditional religious belief system central to the world view of Ojibwa in Canada and the US. It is a highly complex and rich series of sacred teachings and narratives whose preservation enabled the Ojibwa to withstand severe challenges to their entire social fabric throughout the 19th and 20th centuries. It remains an important living and spiritual tradition for many Aboriginal people today. The rituals of the Midewiwin were observed by many 19th century Euro-Americans, most of whom (...) approached these ceremonies with hostility and suspicion. As a result, although there were many accounts of the Midewiwin published in the 19th century, they were often riddled with misinterpretations and inaccuracies. Historian Michael Angel compares the early texts written about the Midewiwin, and identifies major, common misconceptions in these accounts. In his explanation of the historical role played by the Midewiwin, he provides alternative viewpoints and explanations of the significance of the ceremonies, while respecting the sacred and symbolic nature of the Midewiwin rituals, songs, and scrolls. (shrink)

The diverse array of plants at Kew is a haven for wildlife throughout the year. In spring, enchanting wildlfowl babies appear; summer flowers attract a host of insect pollinators; come autumn, parakeets and squirrels raid chestnuts, while in winter swans court – this is Heather Angel’s Wild Kew. In all, a stunning array of photographs and advice, the result of devoting a year to capturing Kew’s wildlife.

Este artículo tiene como objetivo, asumir desde Colombia y América Latina,el texto más renombrado del filósofo alemánWalter Benjamin: Tesis sobre elConcepto de Historia. En mi interpretación, el tiempo histórico incluye larevolución, que Benjamin sitúa en la tradición de Marx y en la “Liga Espartaco” de Alemania, para reivindicar plenamente a los vencidos y excluidos.

This study investigates the relationship between mental health and emotional intelligence among senior high school students in a public school. Thus, the study employed a correlational design to measure the relationship between mental health and emotional intelligence among 152 Grade 12 senior high school students in a public school. Hence, to measure the study’s variables - Mental Health Inventory and Emotional Intelligence Scale (EIS) were utilized. Based on the inferential statistics, the r coefficient of 0.32 indicates a low positive correlation (...) between the variables and a p-value of 0.00, indicating a significant relationship between the respondents' mental health and emotional intelligence. Implications and recommendations were discussed in the study. (shrink)

Este artículo describe el perfil universitario de un maestro que ha dedicado toda su vida a la Universidad: L. Polo. Profesor de casi todas las materias de filosofía, preocupado por el descubrimiento de la verdad en su más alto nivel, por la interdisciplinariedad, etc. Sus cursos, sin repetirse nunca, han sido siempre un pensar en voz alta centrando la atención en los temas centrales. La mayor parte de sus libros son transcripción de esas clases. Su pensamiento se puede describir como (...) una filosofía de la esperanza. (shrink)

There has been longstanding interest in the consistency of decisions made by research ethics committees in the UK, but most of the evidence has come from single studies submitted to multiple committees. A systematic comparison was carried out of the decisions made on 18 purposively selected applications, each of which was reviewed independently by three different RECs in a single strategic health authority. Decisions on 11 applications were consistent, but disparities were found among RECs on decisions on seven applications. An (...) analysis of the agreement between decisions of RECs yielded an overall measure of agreement of κ = 0.286 , indicating a level of agreement that, although probably better than chance, may be described as “slight”. The small sample size limits the robustness of these findings. Further research on reasons for inconsistencies in decision making between RECs, and on the importance of such inconsistencies for a range of arguments, is needed. (shrink)

Recently, some philosophers have defended the idea that knowledge is an interest-relative notion. According to this thesis, whether an agent knows P may depend on the practical costs of her being wrong about P. This perspective marks a radical departure from traditional accounts that take knowledge to be a purely intellectual concept. I think there is much to say on behalf of the interest-relative notion. In this paper, I report on some new evidence which strongly suggests that ordinary people’s attributions (...) of knowledge are in fact sensitive to practical interests. This is noteworthy because recent experiments have been interpreted by many to support the opposite conclusion. I also argue that the new results support an invariantist but interest-relativist account of knowledge, a thesis known as Interest Relative Invariantism (IRI). I do not make the case here that IRI gives us the very best explanation of the results presented here. Any such attempt would require an in-depth survey of the last few decades of work in epistemology. I only want to argue here that IRI gives us a simple and elegant explanation of the new data, and that the same cannot be said about traditional contextualism, a leading competitor to IRI. (shrink)

Big Data evangelists often argue that algorithms make decision-making more informed and objective—a promise hotly contested by critics of these technologies. Yet, to date, most of the debate has focused on the instruments themselves, rather than on how they are used. This article addresses this lack by examining the actual practices surrounding algorithmic technologies. Specifically, drawing on multi-sited ethnographic data, I compare how algorithms are used and interpreted in two institutional contexts with markedly different characteristics: web journalism and criminal justice. (...) I find that there are surprising similarities in how web journalists and legal professionals use algorithms in their work. In both cases, I document a gap between the intended and actual effects of algorithms—a process I analyze as “decoupling.” Second, I identify a gamut of buffering strategies used by both web journalists and legal professionals to minimize the impact of algorithms in their daily work. Those include foot-dragging, gaming, and open critique. Of course, these similarities do not exhaust the differences between the two cases, which are explored in the discussion section. I conclude with a call for further ethnographic work on algorithms in practice as an important empirical check against the dominant rhetoric of algorithmic power. (shrink)

In this paper a formalized logic of propositions, PA1, is presented. It is proven consistent and its relationships to traditional logic, to PM ([15]), to subjunctive (including contrary-to-fact) implication and to the “paradoxes” of material and strict implication are developed. Apart from any intrinsic merit it possesses, its chief significance lies in demonstrating the feasibility of a general logic containing theprinciple of subjunctive contrariety, i.e., the principle that ‘Ifpwere true thenqwould be true’ and ‘Ifpwere true thenqwould be false’ are incompatible.

The production of good sound generation in the violin is a complex task that requires coordination and spatiotemporal control of bowing gestures. The use of motion-capture technologies to improve performance or reduce injury risks in the area of kinesiology is becoming widespread. The combination of motion accuracy and sound quality feedback has the potential of becoming an important aid in violin learning. In this study, we evaluate motion-capture and sound-quality analysis technologies developed inside the context of the TELMI, a technology-enhanced (...) music learning project. We analyzed the sound and bow motion of 50 participants with no prior violin experience while learning to produce a stable sound in the violin. Participants were divided into two groups: the experimental group received real-time visual feedback both on kinematics and sound quality, while participants in the control group practiced without any type of external help. An additional third group of violin experts performed the same task for comparative purposes. After the practice session, all groups were evaluated in a transfer phase without feedback. At the practice phase, the experimental group improved their bowing kinematics in comparison to the control group, but this was at the expense of impairing the sound quality of their performance. At the retention phase, the experimental group showed better results in sound quality, especially concerning control of sound dynamics. Besides, we found that the expert group improved the stability of their sound while using the technology. All in all, these results emphasize the importance of feedback technologies in learning complex tasks, such as musical instrument learning. (shrink)

Research Ethics Committees (RECs) are frequently a focus of complaints from researchers, but evidence about the operation and decisions of RECs tends to be anecdotal. We conducted a systematic study to identify and compare the ethical issues raised in 54 letters to researchers about the same 18 applications submitted to three RECs over one year. The most common type of ethical trouble identified in REC letters related to informed consent, followed by scientific design and conduct, care and protection of research (...) participants, confidentiality, recruitment and documentation. Community considerations were least frequently raised. There was evidence of variability in the ethical troubles identified and the remedies recommended. This analysis suggests that some principles may be more institutionalized than others, and offers some evidence of inconsistency between RECs. Inconsistency is often treated as evidence of incompetence and caprice, but a more sophisticated understanding of the role of RECs and their functioning is required. (shrink)

Because of the COVID-19 pandemic, procrastination has become commonplace due to changes in teaching and learning, which trigger students' academic burnout. As a result, it has increased the intensity of procrastination among students who are enrolled in online learning programs. As a result, students have difficulty as a result of the rapid change from in-person learning to online learning. The study investigates the relationship between academic burnout and procrastination among 150 grade 12 senior high school students. Hence, this study employed (...) a correlational design. Based on the inferential analysis, the r coefficient of 0.71 indicates a high positive correlation between the variables. The p-value of 0.00, which is less than 0.05, leads to the decision to reject the null hypothesis. Hence, a significant relationship exists between academic burnout and academic procrastination among grade 12 senior high school students. (shrink)

Two prevailing accounts of the structure of the mind have been provided, respectively, by the Dual System Theory and by the Massive Modularity Hypothesis. It has been claimed, however, that they cannot both be true at the same time, i.e., that they are incompatible and, thus, that one of them must be abandoned. I will offer some arguments to challenge this claim. I will show that a plausible understanding of each theory makes it possible for them both to be true (...) at the same time. Moreover, I will argue that by appealing to each other they can offer a more complete and detailed account of the architecture of the mind. (shrink)

Sometimes two expressions in a discourse can be about the same thing in a way that makes that very fact evident to the participants. Consider, for example, 'he' and 'John' in 'John went to the store and he bought some milk'. Let us call this 'de jure' coreference. Other times, coreference is 'de facto' as with 'Mark Twain' and 'Samuel Clemens' in a sincere use of 'Mark Twain is not Samuel Clemens'. Here, agents can understand the speech without knowing that (...) the names refer to the same person. After surveying many available linguistic and pragmatic tools (intentions to corefer, presuppositions, meanings, indexing, discourse referents, binding etc.) I conclude that we must posit a new semantic primitive to account for de jure coreference. (shrink)

Igniting a long-overdue dialogue about how the legacy of racial injustice and white supremacy plays out in society at large and Buddhist communities in particular, this urgent call to action outlines a new dharma that takes into account the ways that racism and privilege prevent our collective awakening. The authors traveled around the country to spark an open conversation that brings together the Black prophetic tradition and the wisdom of the Dharma. Bridging the world of spirit and activism, they urge (...) a compassionate response to the systemic, state-sanctioned violence and oppression that has persisted against black people since the slave era. With national attention focused on the recent killings of unarmed black citizens and the response of the Black-centered liberation groups such as Black Lives Matter, Radical Dharma demonstrates how social transformation and personal, spiritual liberation must be articulated and inextricably linked. Rev. angel Kyodo williams, Lama Rod Owens, and Jasmine Syedullah represent a new voice in American Buddhism. Offering their own histories and experiences as illustrations of the types of challenges facing dharma practitioners and teachers who are different from those of the past five decades, they ask how teachings that transcend color, class, and caste are hindered by discrimination and the dynamics of power, shame, and ignorance. Their illuminating argument goes beyond a demand for the equality and inclusion of diverse populations to advancing a new dharma that deconstructs rather than amplifies systems of suffering and prepares us to weigh the shortcomings not only of our own minds but also of our communities. They forge a path toward reconciliation and self-liberation that rests on radical honesty, a common ground where we can drop our need for perfection and propriety and speak as souls. In a society where profit rules, people's value is determined by the color of their skin, and many voices--including queer voices--are silenced, Radical Dharma recasts the concepts of engaged spirituality, social transformation, inclusiveness, and healing. (shrink)

A common theme in social science studies of algorithms is that they are profoundly opaque and function as “black boxes.” Scholars have developed several methodological approaches in order to address algorithmic opacity. Here I argue that we can explicitly enroll algorithms in ethnographic research, which can shed light on unexpected aspects of algorithmic systems—including their opacity. I delineate three meso-level strategies for algorithmic ethnography. The first, algorithmic refraction, examines the reconfigurations that take place when computational software, people, and institutions interact. (...) The second strategy, algorithmic comparison, relies on a similarity-and-difference approach to identify the instruments’ unique features. The third strategy, algorithmic triangulation, enrolls algorithms to help gather rich qualitative data. I conclude by discussing the implications of this toolkit for the study of algorithms and future of ethnographic fieldwork. (shrink)

En este ensayo exploramos una perspectiva epistemológica en la que el elemento social y colectivo del conocimiento juega un papel fundamental en la explicación de su producción y transmisión. Primero presentamos y criticamos una posición individualista que ha sido dominante en la epistemología contemporánea y cuyas raíces pueden trazarse, al menos, hasta Descartes. Posteriormente introducimos y defendemos nuestra propia mirada, una en la que el conocimiento es un proceso constituido por un conjunto de actividades y prácticas que tiene un carácter (...) material. (shrink)

La incorporación de la perspectiva de género en Derecho internacional privado es difícil, por su carácter técnico y abstracto. Las autoridades que aplican estas normas intentan corregir las distorsiones generadas por la ausencia de enfoque de género en esta disciplina a través de correctivos como el orden público internacional, para alcanzar la justicia del caso concreto y proteger derechos fundamentales. Pero, estas correcciones son insuficientes para aplicar la perspectiva de género, porque no remueven los obstáculos que están en el origen (...) de la discriminación de la mujer. La ausencia de perspectiva de género en estas normas es una forma de violencia institucional, que habilita la incorporación en el ordenamiento jurídico de normas que, pretendiendo defender la libertad de la mujer, conducen a normalizar su subordiscriminación. Es precisa una revolución del Derecho internacional privado, que vaya más allá de los efectos inmediatos de las normas reguladoras de las relaciones privadas internacionales. (shrink)

Along this work some feminine characters of El Quijote will standout. Starting from the argument that we find in Celia Amorós’ Time of feminism,this characters will be recaptured, with the purpose of framing the literarywork in the historical development of the spanish feminism that this elaborates.

In lieu of an abstract, here is a brief excerpt of the content:FROM CAIN AND ABEL TO ESAU AND JACOB Angel Barahona UniversidadComplutense, Madrid The theme of twins or of enemy brothers is one which fascinates anthropologists owing to its frequency, the beauty of its mythopoetic settings, and its social significance. The theme always appears in relation to fratricidal violence, and is always linked to myths offoundation or origin. Clyde Kluckhohn in his book about brothers "born in immediate sequence" reminds (...) us that the death of one of them brings with it a momentary peace, the foundation ofa new social order. Thus it is not the fact ofbeing twins, or antagonistic brotherhood per se which is the key to the stories, but violence: Twins are impure in the same way that a warrior steeped in carnage is impure, or an incestuous couple, or a menstruating woman. All forms of violence lead back to violence. We overlook this fact because the primitive concept of a link between the loss ofdistinctions and violence is strange to us; butwe need only consider the calamities primitive people associate with twins to perceive the logic of this concept. Deadly epidemics can result from contact with twins, as can mysterious illnesses mat cause sterility in women and animals. Even more significant to us is the role oftwins in provoking discord among neighbors, a fatal collapse of ritual, the transgression of interdictions—in sort, their part in instigating asacrificial crisis....Behindthe image oftwins lurks the baleful aspectofthesacred, perceived as a disparate but formidableunified force. (Girard 1977, 58) All the mythological, literaryand historical accounts oftwinswhichwe have involve bloody conflict: Eteocles and Polyneices, Romulus and Remus, Richard the Lion Heart and John Lackland, and so on. To a 2 Angel Barahona surprising extent even the development of the different stories is similar. When Polynices departs from Thebes leaving his sister there, hoping to reign through her, he takes with him his fraternal conflict as if it were an attribute of his being. Wherever he goes his brother appears to him, and will oppose him to the death. When an oracle announced to Adrastrus that his two daughters would marry, respectively, a lion and a wild boar, animals which are different in their appearance but identical in their violence, it was presaging fraternal conflict. In Euripides' The Suppliant Women, the king tells how he came upon his sons-in-law. At his door, one night, Polynices and Tideus, both reduced to poverty, were quarreling furiously over possession ofa camp bed. Their brotherhood by virtue ofmarriage with two sisters brings them within the fraternalcategory, likeOedipus and Creon, orDionysus and Pentheus, rival cousins. A plot of land or a kingdom, a woman or an object, the status of firstborn or an unjust inheritance, all give pretexts for conflict. We cannot avoid conflict when desires converge on the same object. It is difficult for the brothers to be aware of their symmetry, their reciprocity, the intense violence which is hidden behind their brotherhood,—an awareness which might spare them their confrontations—because they never occupy the same positions atthe same time. The reciprocity is real, but it is the sum of non-reciprocal moments. The antagonists occupy the same positions in time, but successively, not simultaneously. The same acts and the same sentiments appear in cyclical alternation, but the brothers cannot directly observe their own reciprocity, and thus their identical nature, because they seem to be differentiated by the role which each one plays. Cain and Abel There are many stories ofconfrontations between brothers in Scripture, including those related to the rights of the first born. From Genesis 4,5 onwards we see how these are an interminable source ofconflicts. The first example, Cain and Abel: "And the LORD had regard for Abel and his offering, but for Cain and his offering he had no regard. So Cain was very angry, and his countenance fell" anticipates the themes ofthe blessing and the looking at the face. And we can observe the games of symmetry with the language: "the LORD had regard for Abel and his offering, but forCain and his offering he had no regard." Cain and Abel are presented as an agriculturalist and as a shepherd respectively, two forms ofsocial life. In this quarrel... (shrink)

Diana I. Pérez y Antoni Gomila, Social Cognition and the Second Person in Human Interaction, Routledge, Nueva York, 2022, 194pp., ISBN 978–0–367–67859–3 (hbk); ISBN 978–0–367–67857–9 (pbk); ISBN 978–1–003–13315–5 (ebk).

lntentional ontology. Heidegger and the transformation of Husserlian phenomenology. The article will look inside in what Heidegger said in his first course in Marburgo about the issue of intentionality as the basis for a “fundamental ontological investigation.” Through the first Heidegger’s lessons, especially Freiburg, aspects of the Husserl’s idea of intentionality who suffered a hermeneutic appropriation by Heidegger, will be deployed. The text will focus on the relationship between Husserl’s intentionality and categorial intuition in order to interpret them through the (...) light of hermeneutic and understanding intuition that Heidegger speaks in his 1919’s Kriegsnotsemester. (shrink)