Biological pacemakers can be achieved by various gene‐based and cell‐based approaches. Embryonic stem cells (ESCs)‐derived pacemaker cells might be the most promising way to form biological pacemakers, but there are challenges as to how to control the differentiation of ESCs and to overcome the neoplasia, proarrhythmia, or immunogenicity resulting from the use of ESCs. As a potential approach to solve these difficult problems, tissue‐engineering techniques may provide a precise control on the different cell components of multicellular aggregates and the forming (...) of a construct with‐defined architectures and functional properties. The combined interactions between ESC‐derived pacemaker cells, supporting cells, and matrices may completely reproduce pacemaker properties and result in a steady functional unit to induce rhythmic electrical and contractile activities. As ESCs have a high capability for self‐renewal, proliferation, and potential differentiation, we hypothesize that ESCs can be used as a source of pacemaker cells for tissue‐engineering applications and the ambitious goal of biological cardiac pacemakers may ultimately be achieved with ESCs via tissue‐engineering technology. (shrink)

Biological pacemakers can be achieved by various gene‐based and cell‐based approaches. Embryonic stem cells (ESCs)‐derived pacemaker cells might be the most promising way to form biological pacemakers, but there are challenges as to how to control the differentiation of ESCs and to overcome the neoplasia, proarrhythmia, or immunogenicity resulting from the use of ESCs. As a potential approach to solve these difficult problems, tissue‐engineering techniques may provide a precise control on the different cell components of multicellular aggregates and the forming (...) of a construct with‐defined architectures and functional properties. The combined interactions between ESC‐derived pacemaker cells, supporting cells, and matrices may completely reproduce pacemaker properties and result in a steady functional unit to induce rhythmic electrical and contractile activities. As ESCs have a high capability for self‐renewal, proliferation, and potential differentiation, we hypothesize that ESCs can be used as a source of pacemaker cells for tissue‐engineering applications and the ambitious goal of biological cardiac pacemakers may ultimately be achieved with ESCs via tissue‐engineering technology. -/- . (shrink)

Ben shu xi tong jie shi le zhi jue lun si xiang zai zhong guo xian dai zhe xue fa zhan yan bian de gui ji, Fen xi le liang shu ming, Xiong shi li, Feng you lan, He lin, Mou zong san, Fang dong mei, Tang jun yi deng ren yun yong zhi jue fang fa lai jian gou ge zi zhe xue si xiang ti xi zhi de yu shi, Ji you zhuan ti yan jiu de (...) shen du, You jian gu le shi de guang du, Xian ming gou le chu zhi jue lun zai zhong guo xian dai zhe xue yan jiu zhong de du te lun kuo. (shrink)

In this paper, we employ Weibo Index as the proxy for investor attention and analyze the relationships between investor attention and stock market performance, i.e., trading volume, return, and volatility. The empirical results firstly show that Weibo attention is positively related to trading volume, intraday volatility, and return. Secondly, there exist bidirectional causal relationships between Weibo attention and stock market performance. Thirdly, we generally find that higher Weibo attention indicates higher correlation coefficients with the quantile regression analysis.

A new method of multiattribute decision making is proposed based on the max-min and min-max gray association degree. The gray association coefficients between the alternative, positive ideal solution and negative ideal solution are defined. Here, we construct a bi-objective programming model that maximizes the minimum gray association degree and minimizes the maximum gray association degree simultaneously. By using the linear weighted summation method, the bi-objective programming model is transformed into a linear programming model. Thus, we can obtain the weight vector (...) of attributes by solving the linear programming model. The ranking order of alternatives is generated according to the relative closeness. A numerical example is examined to demonstrate the applicability and implementation process of the decision method proposed in this paper. (shrink)

Ben shu wei "Song Ming shi qi Chang Jiang zhong you de ru xue yan jiu" cong shu zhi yi: ben cong shu shi ren wen she hui ke xue chong dian yan jiu ji di-Wuhan da xue Zhongguo chuan tong wen hua yan jiu zhong xin tou biao, jing jiao yu bu zu zhi zhuan jia ping shen tong guo, zheng shi pi zhun de jiao yu bu ren wen she hui ke xue 2001 nian du zhong da yan (...) jiu xiang mu, xiang mu pi zhun hao shi 01JAZJD720008, ding yu 2004 nian qian hou wan cheng. ke ti zu zhu chi ren wei Guo Qiyong jiao shou, "Jiangxi zhi xue"shi Zhu Xi ti chu de yi ge gai nian, zhu yao zhi chu zi yu Jiangxi Jinxi Lu shi jia zu yi men de xue shuo, qi nei he shi Lu Jiuyuan de xin xue; di 2 quan ze shi you "Song Yuan xue an" suo zai zhi Xiangshan xiong Zhangfu, Suoshan de xue shuo; di 3 quan wei Xiangshan xiong di de di zi men de si xiang. Ben shu quan mian kao cha Jiangxi zhi xue zai Song dai Chang Jiang zhong you xing qi de xue mo yuan yuan, zhu yao xue shuo, yu Luo xue Min xue Zhejiang zhu xue zhe (Lü Zuqian, Yong Shangsi xian sheng deng) zhi jian de guan xi, yi ji qi dui Wang (Yangming) xue xing qi de nei zai guan lian xing, bing yan ji dui xian dai xin ru xue de tan tao. ben shu de xie zuo jiang zhu zhong si xiang kao gu de fang fa, zai quan mian yan jiu you guan dian ji de ji chu shang, dui you guan ren wu de chu sheng di, huo dong de di qu (ru jia zu suo zai cun luo, xue zhe shu xin wang lai, jiang xue, hui jiang, shu yuan deng) jin xing shi di de kao cha, guang fan di yun yong fang zhi, nian pu, shu yuan zhi, jia pu deng cai liao, ba si xiang jia huan yuan yu ju ti huan jing zhi zhong, zai ju ti she hui de li shi de jia zu de bei jing xia kao cha qi si xiang de nei han, jie shi qi jing shen suo zai, bing jin er yin shen chu qi yi yi yu jia zhi. (shrink)

The diffusion of codes is an important processing technology for big data networks. In previous scheme, data analysis was conducted for small samples of big data and complex problems that cannot be processed by big data technology. Due to the limited capacity of intelligence device, a better method is to select a set of nodes to form a connected dominating set to save energy, and constructing CDS is proved to be a complete NP problem. However, it is a challenge to (...) reduce the communication delay and complexity for urgent data transmission in big data. In this paper, an appropriate duty cycle control scheme is proposed to reduce communication delay and complexity while improving energy efficient in CDS-based WSNs. In ADCC scheme, the method for constructing CDS is proposed at lower complexity. Nodes in CDS are selected according to the degree of nodes. Then, duty cycle of dominator nodes in CDS is higher than that of dominated nodes, so the communication delay in the proposed scheme is far less than that of previous scheme. The duty cycle of dominated nodes is small to save energy. This is because the number of dominator nodes in CDS is far less than the number of dominated nodes whose duty cycle is small; thus, the total energy consumption of the network is less than that of the previous scheme. As a result, the performance of energy consumption and communication delay and complex have been improved. Its complexity O∑i=0vm−i+2m−2v−s is reduced a lot for big data. The theoretical analysis shows that compared to the previous scheme, the transmission delay can be reduced 25–92% and the energy efficiency is improved by about 80% while retaining network lifetime. (shrink)

本书从哲学、史学、伦理学、社会学和宗教学等不同角度,对荣辱观的形成和内涵、荣辱观在历史上的传承、以及不同时代荣辱观的异同与比较研究等一系列具有重要学术价值和现实意义的课题,展开多侧面的深入探讨。.

Post-stroke depression is a serious complication of stroke that significantly restricts rehabilitation. The use of immersive virtual reality for stroke survivors is promising. Herein, we investigated the effects of a novel immersive virtual reality training system on PSD and explored induced effective connectivity alterations in emotional networks using multivariate Granger causality analysis. Forty-four patients with PSD were equally allocated into an immersive-virtual reality group and a control group. In addition to their usual rehabilitation treatments, the participants in the immersive-virtual reality (...) group participated in an immersive-virtual reality rehabilitation program, while the patients in the control group received 2D virtual reality rehabilitation training. The Hamilton Depression Rating Scale, modified Barthel Index, and resting-state functional magnetic resonance imaging data were collected before and after a 4-week intervention. rsfMRI data were analyzed using multivariate GCA. We found that the immersive virtual reality training was more effective in improving depression in patients with PSD but had no statistically significant improvement in MBI scores compared to the control group. The GCA showed that the following causal connectivities were strengthened after immersive virtual reality training: from the amygdala, insula, middle temporal gyrus, and caudate nucleus to the dorsolateral prefrontal cortex; from the insula to the medial prefrontal cortex; and from the thalamus to the posterior superior temporal sulcus. These causal connectivities were weakened after treatment in the control group. Our results indicated the neurotherapeutic use of immersive virtual reality rehabilitation as an effective non-pharmacological intervention for PSD; the alteration of causal connectivity in emotional networks might constitute the neural mechanisms underlying immersive-virtual reality rehabilitation in PSD. (shrink)

王學不是“陽儒陰釋”，而是儒學的一種新形態；它與佛教禪宗相似或相同是因為兩者都把“道”內在化了。同時，它也不是“儒體佛用”，確切地說，它是“儒因佛緣”，即它是在“成為聖人”這一儒學的動因中生髮出來的， 佛教因素在其形成過程中只是起了助緣的作用；經過改造的佛教因素成為王學的有機成分，但不是核心要素。.

本书主要探讨和分析先秦儒家义利观思想，侧重于在理论前提、理论内容、理论特质和理论价值四个方面对其进行论述和阐释。作者主要论述了对先秦儒家义利观思想的评价、启示和局限性的解读，指出“人”是“义”与“利” 的统一，不可偏废一端。要借鉴先秦儒家义利观中“义”与“利”的辩证统一关系，在新时代背景下完成“道义”与“利益”的结合。既要将“道义”从“利益”的局限中发展出来，又要始终做到“以人为本”，尊重个体的合理 之“利”，从而使“义”、“利”统一于“人之为人”的价值指向当中。.

本书从教育思想理论、教育实践活动等几维度对董仲舒在中国教育发展史上的地位和影响进行了全面论述和评析。.

倫理是人與人之間的生存法則，也是建立人類社會秩序的基礎。《大英百科全書》有言：「倫理學的同義詞是道德哲學。」可知倫理與道德為一體之兩面。 本書以提綱挈領的方式，講述東西方倫理觀的軌跡、傳承與差異。說理明析，條目清楚，更深入探討倫理道德之重要性，試圖喚醒人們心靈中純正光明之善意，並重視生命內在底蘊的培育積累。 作者游芳憫為海內外備受敬重之儒學專家，廣閱群書，對哲學、史學、神學、社會學等領域均有精深研究，更進而行旅天下，實地觀察世界各方風土民情，本書為其多年研究及講學之學術資料，讀者閱後必能對中西倫理學有一番 全面而系統的認識，是極具研讀價值的入門參考書。【秀威資訊科技股份有限公司製作】.

本书分别对熊十力、陈寅恪、钱钟书的阐释思想进行专门探讨和比较研究。他们的阐释思想分别代表了20世纪中国哲学、史学、文学三个学科的阐释思想所曾达到的最高成就。.

本书收录的儒学研究文章包括:李退溪对朱子的继承和发展、李退溪与奇高峰的四七理气之辩、李退溪心学之研究、李退溪性理学的再研究、宋尤庵与李朝中期的朱子学、李牧隐理学思想简论、林罗山的理学思想、中日韩三国儒 学的历史文化特色、现代化理论视野中的东亚传统。.

本书是以学术史研究方法对东亚文化现代化研究的一个历史考察。笔者在分析韦伯理论以及由此延伸出来的东亚文化现代化理论的合理内核与困境的基础上,以马克思主义理论为出发点,对东亚文化现代化理论建设作进一步的探 讨.

Ben shu yi dong zhong shu zi ran guan wei shi jiao,Chan shu le dong zhong shu de"tian ren gan ying"lun,"wu lei lei bi"he"xun ming de li"de fang fa lun,Yi tian wei yuan ben de yu zhou lun,"bian er you chang"de bian zheng tian dao guan,Yi ji dong zhong shu you guan yuan qi,Yin yang,Wu xing de zi ran ke xue si xiang,Zai zong ti shang ken ding le dong zhong shu zai jie shi he ren (...) shi zi ran gui lü shang de jin bu xing,Ken ding le dong zhong shu dui zhong guo gu dai zi ran ke xue de gong xian,Bing pi ping le yi wang dui dong zhong shu bu gong zheng di ping pan.Ben shu tong shi ye zhi chu le dong zhong shu de mou xie si xiang dui hou shi de fu mian ying xiang. (shrink)

秉春秋之筆 明善惡之辨 ——西漢．董仲舒 本書之成書為研究董仲舒哲學思想之論文集，其研究所據之資料為史漢之〈董仲舒傳〉，董氏之《春秋繁露》。其內容涵蓋董仲舒天人合一之思想、知識論、董氏春秋倫理判斷，以及道德論等。作者在研究中盡力指出董氏所以錯 謬之邏輯推論，以「證偽」，亦襯托其古「董」之精美之處。在中國古代聖賢中所倡言的天人相合的理論裡，不乏有精闢之論，然而其中有其系統而最為專精者，在古代哲人中，則莫過於董仲舒之「天人合一」之論，是以作者對 是事關心而研究焉。.