AimsAlcohol consumption could lead to a series of health problems and social issues. In the current study, we investigated the resting-state functional brain networks of healthy volunteers before and after drinking through graph-theory analysis, aiming to ascertain the effects of acute alcohol intake on topology and information processing mode of the functional brain networks.Materials and methodsThirty-three healthy volunteers were enrolled in this experiment. Each volunteer accepted alcohol breathalyzer tests followed by resting-state magnetic resonance imaging at three time points: before drinking, (...) 0.5 h after drinking, and 1 h after drinking. The data obtained were grouped based on scanning time into control group, 0.5-h group and 1-h group, and post-drinking data were regrouped according to breath alcohol concentration (BrAC) into relative low BrAC group (A group; 0.5-h data, n = 17; 1-h data, n = 16) and relative high BrAC group (B group; 0.5-h data, n = 16; 1-h data, n = 17). The graph-theory approach was adopted to construct whole-brain functional networks and identify the differences of network topological properties among all the groups.ResultsThe network topology of most groups was altered after drinking, with the B group presenting the most alterations. For global network measures, B group exhibited increased global efficiency, Synchronization, and decreased local efficiency, clustering coefficient, normalized clustering coefficient, characteristic path length, normalized characteristic path length, as compared to control group. Regarding nodal network measures, nodal clustering coefficient and nodal local efficiency of some nodes were lower in B group than control group. These changes suggested that the network integration ability and synchrony improved, while the segregation ability diminished.ConclusionThis study revealed the effects of acute alcohol intake on the topology and information processing mode of resting-state functional brain networks, providing new perceptions and insights into the effects of alcohol on the brain. (shrink)

In the literature, CSR’s roles on firm performance are found to be positive, negative, or neutral. This inconclusive pattern suggests there may be a more complicated mechanism at work than the traditional focus on simple linear associations. We propose and test an inverted-U-shaped relationship between CSR and shareholder value, the fundamental measure of firm performance. Further, we incorporate a critical firm attribute, marketing capability, to moderate the nonlinear link between CSR and shareholder value, thereby exploring a previous understudied area involving (...) the interplay between CSR and market-side competency. The results show that an initial increase in CSR engagement positively drives firm shareholder value, but the effect turns negative when a firm pursues excessive CSR engagement. Notably, however, this negative association does not apply to firms that have a high marketing capability. Our research generates meaningful implications for a stakeholder view of CSR, strategic management, firm valuation, resource-based theories, and business practices. (shrink)

Current methods of reprogramming differentiated cells into induced pluripotent stem cells remain slow and inefficient. In a recent report published online in Nature, Bhutani et al.1 developed a cell fusion strategy, achieving quick and efficient reprogramming toward pluripotency. Using this assay, they identified an immune system protein called activation‐induced cytidine deaminase, or AID, which unexpectedly is actually able to “aid” in reprogramming due to its involvement in DNA demethylation that is required for induction of the two key pluripotency genes, Oct4 (...) and Nanog. More recently, Popp et al. 2 also reported online in Nature that AID is important for complete cell reprogramming in mammals. Together, these findings provide new insights into how cells are reprogrammed, identify the specific role of AID in cell fate reversal, and advance the field of regenerative medicine. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Physiognomy in Ming China: Fortune and the Body by Xing WangWenbin Wang (bio)Physiognomy in Ming China: Fortune and the Body. By Xing Wang. Leiden: Brill, 2020. Pp. x+ 325. Hardcover €114.00, ISBN 978-90-04-42954-3.Physiognomy (xiangshu 相術) as a technique of fortune-telling via the observation of the body has a long history in China and is still a living tradition. As a part of the traditional Chinese technological repertoire of (...) "Techniques and Methods" (fangshu 方術), records of performing physiognomy date back to the Spring and Autumn period (8th-5th centuries B.C.) (p. 31). According to Lisa Raphals, physiognomy was a crucial part of early Chinese philosophical discussion of the body, cosmology and human existence.1 Yet Wang Xing argues that despite its long history, our knowledge of Chinese physiognomy before the Ming dynasty is rather limited due to the small amount of pre-Ming physiognomy manuscripts still in existence. Chinese physiognomy as we know it today is largely based on its predecessors in late imperial China, and it was during the late Ming that most of the well-known extant physiognomy manuals were produced (p. 34). In contrast, the paucity of academic surveys of Ming physiognomy means that when it comes to scholarly examination of Chinese physiognomic texts and academic representation of physiognomic theories, misinterpretation often occurs. Wang is particularly critical of an early academic work on Chinese physiognomy by American anthropologist William Lessa, who made many dubious and broad assertions about the origin and characteristics of Chinese physiognomy (p. 15).2 In this context, Wang's Physiognomy in Ming China: Fortune and the Body is the first monograph in the English-speaking world primarily dedicated to the study of Chinese physiognomy in the Ming dynasty, including its social, textual, intellectual and technological history. It is also the first work in English that comprehensively introduces the history of Chinese physiognomy in early to late imperial China.Wang's investigation of this topic is two-fold. On the one hand he tackles physiognomy manuals and records of physiognomy practice from a historical perspective. Wang uses a very famous Ming physiognomic "encyclopedia," The Compendium of Divine Physiognomy (Shenxiang quanbian 神相全編), as the main text in his discussion of physiognomic knowledge, as well as a large amount of anecdotal writings from the Song to Ming periods. On the other hand, Wang consciously draws links between Chinese physiognomic theories and modern Western philosophical and anthropological debates on the body, symbolism and phenomenology. To push forward this conversation, Wang establishes a unique [End Page 1] framework for interpreting the conceptualization of the body, fortune and the cosmos in Ming physiognomic texts: the "homological" body on which time is "spatialized," discussed further below. It is this second facet of the argument that could most intrigue and inspire scholars of Chinese philosophy like myself. As Marta Hanson comments, Wang's work is an excellent example of how Chinese technical as well as cosmological works could problematize and challenge modern Euro-American academic theorizations of Asian culture and how professional sinological study could contribute to salient modern intellectual debates.3 When reading Wang's book, readers should always bear in mind his intention to bring together Ming physiognomic theories with broader contemporary philosophical discourse.Apart from the introduction, there are seven chapters in the book. The first two chapters serve as the historical section of the discussion (although historical analysis is also an indispensable part of later chapters). Chapter 1 provides readers with an overall background to physiognomy in China, especially its categorization as a form of elite knowledge in traditional catalogues, the development of core physiognomic theories and concepts in relation to traditional Chinese cosmology and medical theories, and the textual history of Ming physiognomy manuals. Beyond providing general information, in my view the author here makes three outstanding points: the first is that what we know as Chinese physiognomy is actually not merely a technique of human body divination, but also a method of predicting human future via observing the whole material world. Wang mentions a very important branch of physiognomy in historical catalogues called "physiognomy of things" (xiangwu 相物) (p. 27), in which anything from a horse... (shrink)

The traditional understanding of corporate social responsibility (CSR) has largely been focused on its downstream performance implications, particularly its associations with firms’ customer market metrics such as customer loyalty, customer satisfaction and customer co-creation as well as financial ones such as firm value, return on assets etc. However, given the close relationship between CSR and marketing that literature has identified, it is surprising that the relationship between a focal upstream construct, i.e. the marketing function’s power within a firm and the (...) firm’s propensity toward CSR has not been addressed in the literature. Examining the link between marketing’s power (MP) in a firm’s top management team (TMT) and firm CSR levels, we investigate how this fundamental TMT configuration, i.e. the distribution of marketing power in the TMT, motivates the firm’s social endeavors. Further, we formulate this relationship in a contingency-based model that incorporates the moderating effects of firm size, firm age, service intensity, and resource slack across 1569 firms operating in 63 industries. In addition to their effect on CSR, this study shows how MP in TMT may influence corporate social irresponsibility (CSI) as well as CSR capability after controlling for industry type. The inclusion on these additional dimensions of CSR (CSI and CSR capability) complements our analyses of the effect that MP has on CSR. The research contributes to a deeper understanding of CSR’s fundamental corporate determinants as well as identifies the essential role of the marketing function in firms’ CSR strategy. In this process, it yields useful implications for multiple streams of theory as well as for business practices. (shrink)

Study of the religious thoughts of Muḥammad Taqī Miṣbāḥ Yazdī on Islamic ethics, God and values.

Theoretical evidence suggests that corporate social irresponsibility (CSI) should produce long-lasting negative influences on firm performance. Yet, little empirical evidence exists in the literature to support this time-embedded research frame. This research was conducted by collecting a large set of firm data and by employing a series of vector autoregressive models to map out the longitudinal dynamic relationships between CSI and firm value under high versus low levels of two external factors, environmental dynamism and competition intensity, and one internal factor, (...) firm capability. The results show that CSI’s negative influences endure in scenarios such as high dynamism, high competition intensity, and low capability, but it has only a short-term impact on low-dynamism markets and does not produce significant effects on firm value under low-competition or high-capability conditions. These findings yield useful implications for CSI, resource-based theory, and environment theories as well as for managerial effectiveness of coping with social negativities. (shrink)

al-Shirwānī's glosses on Jurjānī's glosses on al-Urmawī's Maṭāliʻ al-anwār on Arabic logic.

Dialogues on memory (Philosophy) along with the text of Professor Paul Ricoeur's lecture on memory.

Through a systematic introduction of Confucius as a historical figure, a spiritual leader, a philosopher, a political reformer, an educator, and a person, this book offers a comprehensive, lucid, and in-depth articulation of Confucius and his teachings for Western students.

Counterfactual thinking is presumed to play a preparatory function in promoting people’s behavioural intentions. This study specifically addresses the impacts of COVID-19 severity, tourists’ counterfactual thinking about the pandemic, and tourists’ perceived duty-free consumption value on the effect of a duty-free policy on travel intentions. Four hundred and ten participants took part in this study, which involved a 2 × 2 design. Results reveal the following patterns: compared to the absence of a duty-free policy in tourist destinations, enactment of a (...) duty-free policy leads to stronger visit intentions through greater perceived value and the effect of a duty-free policy on travel intention is moderated by tourists’ counterfactual thinking and COVID-19 severity. (shrink)

While the concept of Menschenwürde (universal human dignity) has served as the foundation for human rights, it is absent in the Confucian tradition. However, this does not mean that Confucianism has no resources for a broadly construed notion of human dignity. Beginning with two underlying dilemmas in the notion of Menschenwürde and explaining how Confucianism is able to avoid them, this essay articulates numerous unique features of a Confucian account of human dignity, and shows that the Confucian account goes beyond (...) the limitations of Menschenwürde. It is arguably richer and more sophisticated in content, and more constructive for protecting and cultivating human dignity. (shrink)

صدر عن المركز العربي للأبحاث ودراسة السياسات كتاب المولدي عزديني فلسفة القيم النقدية عند نيتشه: استشكال الإتيقا وسؤال النقد الجذري. يشتمل الكتاب على 380 صفحة، وقائمة ببليوغرافية، وفهرس عام. يسعى هذا الكتاب إلى دراسة طبيعة العلاقة بين "استشكال الإتيقا" (تأسيس حقل قيم نقدي متعلق بشكل الحياة الحرة، يقع في ما وراء الخير والشر، أي في ما وراء المفهوم التقليدي للأخلاق) من ناحية، و"سؤال النقد الجذري" (أي "الجينيالوجي") للمنظومة التقليدية للأخلاق من ناحية أخرى، ويحاول استكشاف ميدان "الإتيقا" بوصفه حقلًا مستقلًا من (...) المسائل مختلفًا عن فلسفة الأخلاق التقليدية. يقوم الكتاب على التحليل الداخلي للنصوص والانخراط في روح الفيلسوف، من أجل فهمه وشرح مفاهيمه وبسط أطروحاته، على نحو جامع، في كتابات فريدريش فيلهيلم نيتشه. وتتمثل قيمته البحثية المضافة، أيضًا، في تقديم عملٍ متكامل في مسألةٍ ظلَّ التطرق إليها باللغة العربية جزئيًّا فحسب. (shrink)

On Islamic philosophy with special reference to logic in Islamic philosophy.

Cancer care has transitioned from clinical-based to home-based care to support longterm care in a more familiar and comfortable environment. This care transition has put family caregivers (FCGs) in a strategic position as care providers. Cancer care at home involves psychological and emotional treatment at some point, making FCGs deal with the stress of cancer patients frequently. Due to their limited care competencies, they need supportive care from healthcare professionals in cancer stress management. This study aims to examine how types (...) of demanded healthcare information affect the FCG’s role in reducing the stress of female cancer patients. The mindsponge theory was used in conceptual development and interpretation. Bayesian Mindsponge Framework (BMF) analytics were used for statistical analysis on a dataset of 48 spouses (husbands) and 12 other family members in five congested communities of Surabaya, Indonesia. Results showed that among the six types of healthcare information, FCGs with higher demand for cancer-specific information were more likely to need support in reducing the stress of female cancer patients. Meanwhile, FCGs with a higher demand for information about support services were less likely to need support to reduce cancer patients’ stress. Other types of healthcare information have ambiguous effects on the need for support in reducing cancer-induced stress. This study reveals that the demanded cancer-specific information, e.g., cancer prognosis or likely outcome, must be prioritized to assist FCG’s role in managing cancer stress. (shrink)

Adaptation and stress are two main concepts useful for better understanding the phases of illness and health-related human behavior. The two faces of adaptation, adaptation as a process and adaptation as a product, have raised the question of how long the adaptation process will take in cancer trajectories. The care setting transition from clinical-based into home-based cancer care has stressed the role of family caregivers (FCG) in cancer management. This study examines how types of demanded healthcare information affect the FCG’s (...) role in catalyzing the adaptation of female cancer patients. The mindsponge theory was used in conceptual development and results interpretation. Bayesian Mindsponge Framework (BMF) analytics was used for statistical analysis on a dataset of 48 spouses (husbands) and 12 other family members in five congested communities of Surabaya, Indonesia. Results showed that among the six types of demanded healthcare information, FCGs with a higher tendency to demand cancer-specific information are more likely to need support in catalyzing the adaptation of female cancer patients. Meanwhile, FCGs with a higher demand for information on alternative therapies are less likely to need support in catalyzing cancer adaptation. Other types of healthcare information have ambiguous effects on the need for support in cancer adaptation assistance. This study reveals that the demanded cancer-specific information, e.g., cancer’s prognosis or likely outcome, must be prioritized to assist FCG’s role in catalyzing adaptation among female cancer patients. Cancer prognosis and outcomes reflect the future of cancer care results. (shrink)

This brief text assists students in understanding Confucius' philosophy and thinking so they can more fully engage in useful, intelligent class dialogue and improve their understanding of course content. Part of the Wadsworth Notes Series,, ON CONFUCIUS is written by a philosopher deeply versed in the philosophy of this key thinker. Like other books in the series, this concise book offers sufficient insight into the thinking of a notable philosopher, better enabling students to engage in reading and to discuss the (...) material in class and on paper. (shrink)

Glosses on a work by Gelenbevî on logic.

Portion of the ancient Hindu epic, on fundamentals of the Vedanta school in Hindu philosophy.

This brief text assists students in understanding Reid's philosophy and thinking so they can more fully engage in useful, intelligent class dialogue and improve their understanding of course content. Part of the Wadsworth Notes Series,, ON REID is written by a philosopher deeply versed in the philosophy of this key thinker. Like other books in the series, this concise book offers sufficient insight into the thinking of a notable philosopher, better enabling students to engage in reading and to discuss the (...) material in class and on paper. (shrink)

Different from the commonly used moralistic perspective, this article articulates and evaluates major ideas about human desire within the Confucian tradition through a gongfu perspective, and shows that, although there are historical reasons for blaming Confucianism for suppressing human desires and suffocating humanity, what classic Confucianism advocates is ultimately about how to cultivate humanity, transform human desires, and live artistically, and not imposing a rigid normative moral system externally to constrain human life, making it unsatisfying.

This paper tries to explore a gongfu ethics on the basis of traditional Chinese ethical theories. Used in the sense that the Song-Ming Neo-Confucians did, “gongfu” means the art of life in general and not merely the martial arts, although martial arts can be taken as a paradigm example of gongfu. The paper begins with the question “can bad guys have good gongfu,” which leads to three answers, each representing one stage of the dynamic relationship between morality and gongfu: The (...) first is yes, since gongfu and morality belong to two different categories, i.e., the art of life and moral responsibilities. The second is no, because each moral goodness or badness corresponds to a respective gongfu virtuosity or the lack of it. The third answer is that moral persons, as long as they still have to invoke morality, are not true gongfu masters. Those who have real good gongfu transcend moral duties and become amoral. The analysis suggests a gongfu ethics that can include, but goes beyond moral goodness. The rest of the essay articulates the rich implications of this gongfu ethics by comparing it with virtue ethics, consequentialist ethics, and relativism-subjectivism. (shrink)

This study examines whether and how board gender diversity can affect corporate wage inequity by drawing on diversity theory and gender socialization and ethicality theories. Building on an exogenous relaxation of China’s one-child policy (OCP) in 2013, which led to a substantial decline in the female labor force participation rate. Our empirical analysis suggests that board gender diversity is negatively associated with corporate wage inequity. This result is robust to various endogeneity and sensitivity analyses. We find that the OCP relaxation (...) only increases average executive pay; it does not affect employee pay. One potential mechanism driving our results is that the decline in board gender diversity caused by the OCP relaxation reduces supervision, restriction, and fairness within the firm, which increases executives’ pursuit of personal interests and ultimately leads to the rise of wage inequity. Our findings are particularly significant for firms in capital-intensive industries, firms with a low level of employee bargaining power, and large firms. (shrink)