Deep brain stimulation is a clinical intervention for the treatment of movement disorders. It has also been applied to the treatment of psychiatric disorders such as depression, anorexia nervosa, obsessive-compulsive disorder, and schizophrenia. Psychiatric disorders including schizophrenia, bipolar disorder, and major depression can lead to psychosis, which can cause patients to lose touch with reality. The ventral tegmental area, located near the midline of the midbrain, is an important region involved in psychosis. However, the clinical application of electrical stimulation of (...) the VTA to treat psychotic diseases has been limited, and related mechanisms have not been thoroughly studied. In the present study, hyperlocomotion and stereotyped behaviors of the mice were employed to mimic and evaluate the positive-psychotic-like behaviors. We attempted to treat positive psychotic-like behaviors by electrically stimulating the VTA in mice and exploring the neural mechanisms behind behavioral effects. Local field potential recording and in vivo fiber photometry to observe the behavioral effects and changes in neural activities caused by DBS in the VTA of mice. Optogenetic techniques were used to verify the neural mechanisms underlying the behavioral effects induced by DBS. Our results showed that electrical stimulation of the VTA activates local gamma-aminobutyric acid neurons, and dopamine neurons, reduces hyperlocomotion, and relieves stereotyped behaviors induced by MK-801 injection. The results of optogenetic manipulation showed that the activation of the VTA GABA neurons, but not DA neurons, is involved in the alleviation of hyperlocomotion and stereotyped behaviors. We visualized changes in the activity of specific types in specific brain areas induced by DBS, and explored the neural mechanism of DBS in alleviating positive psychotic-like behaviors. This preclinical study not only proposes new technical means of exploring the mechanism of DBS, but also provides experimental justification for the clinical treatment of psychotic diseases by electrical stimulation of the VTA. (shrink)

Resumen: La civilización China siempre ha sido conocida como la civilización de los rituales y la música, con la música jugando un papel importante a lo largo de las dinastías. El desarrollo de la música tradicional China no puede separarse de la inyección de varias ideas filosóficas y conciencia social. Ya sea el sistema de música ritual de la dinastía Zhou, las cien escuelas de pensamiento durante el período de los reinos combatientes, las discusiones metafísicas de las dinast Wei y (...) Jin, o la filosofía budista de las dinast Han y Tang, cada era ha jugado un importante papel catalizador en la formación de la teoría estética de la música tradicional China. Este artículo resume el proceso de desarrollo histórico de la cultura musical tradicional China. También analiza el proceso de construcción de la filosofía estética de la música tradicional China desde las perspectivas de las tres principales escuelas filosóficas: confucianismo, budismo y taoísmo. Estas tres escuelas han tenido el impacto más profundo en la música tradicional China. (shrink)

本书阐述的是一种独特而圆润的人生哲学,在统揽古今中外人生哲学的基础上提出了自己认为的人生哲学。本书也是一种别开生面的中西简明哲学史,以人生哲学为切入点,对中国古代哲学、西方古典哲学以及欧美现代哲学等提 出了自己的真知灼见。.

e-commerce has promoted the application of the Internet by traditional enterprises. While this phenomenon has deepened industrial embeddedness, it has also profoundly affected the development of traditional manufacturing and retail industries. Based on the embeddedness theory, this paper takes the e-commerce industrial chain in Xiong’an New Area of China as an example, uses location entropy method and local spatial autocorrelation to analyze its spatial characteristics and influencing factors, and also discusses the features of embeddedness from each dimension of industrial chains. (...) The results show the following: ① The supply chain of industry-dependent e-commerce is dominated by production wholesalers, and suppliers with cost advantages and commercial traditions are embedded in local characteristic industries; the e-commerce value chain is dominated by production and processing activities, and the spatial orientation of the business model is affected by regional industrial functions; the e-commerce enterprise chain is dominated by B2B enterprises, the high-level agglomeration of which reflects the absolute scale advantage provided by the e-commercialization of traditional industry. ② The distribution of the e-commerce industrial chains of Xiong’an New Area is characterized by spatial heterogeneity and has obvious spatial agglomeration. The industrial chains are concentrated in Xiong County, followed by Rongcheng County, and Anxin County has the weakest agglomeration. ③ The main factors that cause the uneven distribution of the e-commerce industrial chains in Xiong’an New Area include three aspects: transportation location advantages, traditional industrial foundation, and government policy regulation. Research can provide a scientific reference for accurately identifying the spatial development characteristics of the industrial chains from various perspectives and promoting the sustainable development and e-commercialization of traditional industries. (shrink)

Previous studies have shown that changes in gray matter density and volume in the left primary motor cortex are significantly associated with changes in individuals’ verbal intelligence quotient, but not with their performance intelligence quotient. In the present study, we examined the effects of transcranial direct current stimulation over the left primary motor cortex on performance in intelligence tests. We chose four subtests of the Wechsler Adult Intelligence Scale-Chinese Revised version and randomized participants into anodal, cathodal, and sham groups. We (...) found that anodal stimulation significantly improved performance in verbal intelligence subtests compared to cathodal and sham stimulation, while performance intelligence subtest scores did not change in any stimulation condition. These findings suggest that the excitation level of the left primary motor cortex has a unique effect on verbal intelligence. (shrink)

This paper argues that the proliferation of the new term ‘baby man’ has an impact on reconstructing established gender relationships and resisting China's authoritarian political power in a highly-censored online environment. This study employs feminist critical discourse analysis to investigate how Chinese feminism adopts the discursive construction of ‘baby man’ and how they echo the complex historical and sociocultural backgrounds through a case study of 43 posts containing ‘baby man’ on Chinese social media. The finding suggests that the term ‘baby (...) man’ is employed in discursive strategies, namely, double irony, the blunt resistance against both gender and power relationships that deconstruct the heteropatriarchal gender norm through the mother – son female gaze and contempt for the nation's past and current population policy. It argues that despite perennial censorship, these three discursive strategies help reconstruct the extant gender hierarchy backed by conservative Confucianist ethics and represent a grassroots challenge to the political authoritarianism indoctrinated by the state. (shrink)

Quasi-realists have proposed an “internal” reading of the mind-independence claim embedded in our moral discourse, according to which the claim to mind-independence itself is a moral claim. I argue against such a quasi-realist “internal” reading. My objection is that quasi-realists cannot plausibly explain why the majority of us, either implicitly or explicitly, take moral mind-independence to be a metaethical notion. Quasi-realists either must attribute a quite obvious mistake to most metaethical theorists without explaining why they cannot recognize it, or give (...) us an intolerably ad hoc explanation about why ordinary moral speakers fail to understand their own words. Without properly addressing this problem, we have good reason to reject the quasi-realist account of moral mind-independence. (shrink)

A non‐normative, response‐dependent view about morality can avoid metaphysical extravagance and explain why the extension of some non‐normative concepts can non‐accidentally match the extension of moral concepts. These features make it a plausible reductive account of moral properties. However, some philosophers believe that a response‐dependent account of morality must contain an irreducibly normative component. I argue that it is impossible to defend such a position while retaining the response‐dependent nature of morality in the ordinary sense. However, I believe that philosophers' (...) motivation for engaging in such a philosophical project should be taken seriously. The underlying concern is that the plausibility of a response‐dependent view makes people's strong commitment to irreducible normativity a puzzle that requires an explanation. I explain why people systematically fail to give up this commitment without claiming that they rationally cannot give it up, which means a non‐normative response‐dependent view is immune from such a challenge. (shrink)

Law article prediction is a task of predicting the relevant laws and regulations involved in a case according to the description text of the case, and it has broad application prospects in improving judicial efficiency. In the existing research work, researchers often only consider a single case, employing the neural network method to extract features for prediction, which lack the mining of related and common element information between different data. In order to solve this problem, we propose a law article (...) prediction method that integrates the characteristics of common elements. It can effectively utilize the co-occurrence information of the training data, fully mine the relevant common elements between cases, and fuse local features. Experiments show that our method performs well. (shrink)

This study investigates the use of modal verbs in Chinese–English government press conference interpretation. Modal verbs mark the speaker’s opinion of or attitude toward the event described in a sentence. Interpreters also use modal verbs to indicate the stances of the source language speakers. The use of modal verbs has been examined in such contexts as research papers, textbooks, and second language learners’ output; however, studies that compare differences in modal verbs between source and target languages in the context of (...) interpreting are sparse. The investigation being reported is based on a comparable corpus—an original Chinese GPC and its English-translated version—and a parallel corpus—a translated English GPC and the original English version from the US. The results of the comparable corpus analysis indicate that the frequency of modal verbs in translated English is significantly higher than in original Chinese, in which only 40% of the modal verbs in translated English are consistent with their Chinese counterparts, while others are employed through amplification and value variation. The results of the parallel corpus analysis suggest that the increase of modal verbs in the target texts may help to achieve certain types of pragmatic functions in English. (shrink)

艾丰(1938~),河北玉田人,人民日报编委、经济部主任、高级记者,兼任中国社会科学院研究生院教授,中国人民大学新闻学院教授.

艾丰(1938~),河北玉田人,人民日报编委、经济部主任、高级记者,兼任中国社会科学院研究生院教授,中国人民大学新闻学院教授.

BackgroundThe US Food and Drug Administration (FDA) regulates goods accounting for 20% of US consumers’ total expenditure. The agency’s potential susceptibility to corporate lobbying and political influence may adversely affect the its abilities to fulfill its duties as a vital federal agency. This study assesses whether the FDA’s product recall classifications in recall scenarios are influenced by firms’ lobbying activities.MethodsThe universe of all FDA recalls between 2012 and 2019 is obtained from the FDA’s website. Firm names are matched to federal-level (...) lobbying data obtained from the Center for Responsive Politics – a non-profit and nonpartisan organization that tracks lobbying expenditures and campaign contributions. Analyses are conducted using ordinary-least-squares regressions, in which the dependent variable is recall classification and independent variables are three different measures of firms’ lobbying activities in the one year prior to the recall.ResultsFirms that engage in lobbying appear more likely to receive favourable classifications from the FDA. When examining the above results by product type, we find that classification of food recalls seems to be subject to lobbying influence, but the same does not appear to be true for drug and device recalls. Evidence is consistent with the conjecture that the distinction between medical and food firms may be a result of medical firms targeting lobbying efforts at FDA approvals, rather than recalls.ConclusionsBetween 2012 and 2019, the FDA’s product recall classifications seem to be significantly influenced by firms’ lobbying activities. Lobbying firms appear to have received more favorable (i.e., less severe) recall classifications compared to non-lobbying firms. (shrink)

Delay in seeking medical services is common in elderly populations, which leads to disease progression and life difficulty. This study aims to assess the prevalence of delay in medical visits and treatment and define associated effects and factors in patients with senile cataract, which may help obtain a better understanding of late-life psychopathology and provide the basis for interventions. Patients aged more than 60 years were prospectively recruited in Zhongshan Ophthalmic Center. All participants were diagnosed with binocular senile cataract and (...) decided to have primary surgery in ZOC. The distributions of the popularity of delaying outpatient visits and treatment, the degrees of visual impairment, the influences on quality of life, and the reasons for delaying treatment among participants were accessed by the descriptive statistics. Factors associated with the perceptions of cataract treatment were accessed using a binary logistic regression model. A total of 400 senile patients aged from 60 to 94 years were enrolled. At diagnosis, 82 participants had a low vision with monocular acuity of both eyes below 0.05. All participants have felt that their normal lives were affected, and 64 participants felt that their lives were affected severely. Only 17 participants have sought for medical services immediately after feeling vision loss, and 294 participants have felt vision loss since a year ago before seeking medical help. A total of 298 participants have delayed the surgery time, and 229 patients delayed it for more than 12 months. There were 147 participants delaying surgery on account of no knowledge about it and 114 participants delaying surgery because of fear. There are a high proportion of elderly patients with senile cataract delaying their outpatient visits and surgery treatment, whose normal lives were severely affected. Increasing medical service propaganda about cataract and other common diseases in elderly populations would probably be helpful for improving perceptions of diseases and decreasing medical delays. Public needs to draw more attention to the healthy and medical status of the elderly ocular patients. (shrink)

We extend Savage et al.'s music and social bonding hypothesis by examining it in the context of Chinese music. First, top-down functions such as music as political instrument should receive more attention. Second, solo performance can serve as important cues for social identity. Third, a right match between the tones in lyrics and music contributes also to social bonding.

It is not only difficult to be a sports expert but also difficult to grow from a sports expert to a sports elite. Professional athletes are often concerned about the differences between an expert and an elite and how to eventually become an elite athlete. To explore the differences in brain neural mechanism between experts and elites in the process of motor behavior and reveal the internal connection between motor performance and brain activity, we collected and analyzed the electroencephalography findings (...) of 14 national archers and 14 provincial archers during aiming and resting states and constructed the EEG brain network of the two archer groups based on weighted phase lag index; the graph theory was used to analyze and compare the network characteristics via local network and global network topologies. The results showed that compared with the expert archers, the elite archers had stronger functional coupling in beta1 and beta2 bands, and the difference was evident in the frontal and central regions; in terms of global characteristics of brain network topology, the average clustering coefficient and global efficiency of elite archers were significantly higher than that of expert archers, and the eigenvector centrality of expert archers was higher; for local characteristics, elite archers had higher local efficient; and the brain network characteristics of expert archers showed a strong correlation with archery performance. This suggests that compared with expert archers, elite archers showed stronger functional coupling, higher integration efficiency of global and local information, and more independent performance in the archery process. These findings reveal the differences in brain electrical network topologies between elite and expert archers in the archery preparation stage, which is expected to provide theoretical reference for further training and promotion of professional athletes. (shrink)

Concerns with improper collection and usage of personal information by businesses or governments have been seen as critical to the success of the emerging electronic commerce. In this regard, computer professionals have the oversight responsibility for information privacy because they have the most extensive knowledge of their organization's systems and programs, as well as an intimate understanding of the data. Thus, the competence of these professionals in ensuring sound practice of information privacy is of great importance to both researchers and (...) practitioners. This research addresses the question of whether male computer professionals differ from their female counterparts in their self-regulatory efficacy to protect personal information privacy. A total of 103 male and 65 female subjects surveyed in Taiwan responded to a 10-item questionnaire that includes three measures: protection (protecting privacy information), non-distribution (not distributing privacy information to others), and non-acquisition (not acquiring privacy information). The findings show (1) significant gender differences exist in the subjects' overall self-regulatory efficacy for information privacy, and, in particular, (2) that female subjects in this study exhibited a higher level of self-regulatory efficacy than males for the protection and non-acquisition of personal privacy information. The identification of the factorial structure of the self-regulatory efficacy concerning information privacy may contribute to future research directed to examining the links between privacy efficacy and psychological variables, such as ethical attitude, ethical intention, and self-esteem. Studies can also be extended to investigate how different cultural practices of morality and computer use in men and women may shape the different development patterns of privacy self-efficacy. Understanding the different cultural practices may then shed light on the social sources of privacy competence and the appropriate remedies that can be provided to improve the situation. (shrink)

Available evidence highlights the importance of emotion regulation in psychological well-being. However, translation of the beneficial effects of ER from laboratory to real-life remains scarce. Here, we present proof-of-principle evidence from a novel cognitive-emotional training intervention targeting the development of ER skills aimed at increasing resilience against emotional distress. This pilot intervention involved training military veterans over 5–8 weeks in applying two effective ER strategies [Focused Attention and Cognitive Reappraisal ] to scenarios presenting emotional conflicts. Training was preceded and followed (...) by neuropsychological, personality, and clinical assessments, and resting-state functional MRI data were also collected from a subsample of the participants. Results show enhanced executive function and psychological well-being following training, reflected in increased working memory, post-traumatic growth, and general self-efficacy. Brain imaging results showed evidence of diminished bottom-up influences from emotional and perceptual brain regions, along with evidence of normalized functional connectivity in the large-scale functional networks following training. The latter was reflected in increased connectivity among cognitive and emotion control regions and across regions of self-referential and control networks. Overall, our results provide proof-of-concept evidence that resilience and well-being can be learned through ER training, and that training-related improvements manifested in both behavioral change and neuroplasticity can translate into real-life benefits. (shrink)

This study examines the Korean translations of a Japanese work Joshi no rongo [女子の論語/Women’s Analects] (Yuki, Ako [祐木亜子]. 2011. 女子の論語. Tokyo: Sunmark Publishing House), a modern interpretation of the Chinese classic The Analects, with a view to identifying how the paratexts of a translated text contributed, or hindered the reception of the work in the target culture. By drawing on Gérard Genette’s (1997 [1987]. Paratexts: Threshold of interpretation, Jane E. Lewin (trans.). Cambridge: Cambridge University Press) concept of “paratexts,” this study (...) both analyses translation shifts in the peritexts (e.g., cover, foreword, table of contents) and the epitexts (reviews) of the Korean translations. The analysis shows that the additions and rearrangements of some paratextual elements in the Korean translation further reinforced the traditional view presented in the source text, which ironically brought about heavy criticisms of the original Japanese text and resulted in the Korean retranslation of the work. The scrutiny of peritexts and epitexts in this article will enhance our understanding of the interactions between the translator, the publisher, and the public readers, which jointly contextualize the production and reception of a translated work in a given culture. (shrink)

BackgroundPhysical activity has a significant health impact worldwide and has been linked to a lower risk of the common cold.ObjectiveThe aim of this study was to estimate the form of PA among Chinese adults and the correlation between PA and number of the common cold in China's eastern, central, and western areas.DesignA cross-sectional study.SettingChina's eastern, central, and western regions from 30 November 2020 to 30 March 2021.PatientsA total of 1,920 healthy participants, who aged over 18 years old, with Internet access, (...) were enrolled, and then self-reported PA behaviors and number of the common cold were collected.MeasurementsThe authors calculated preference, intensity, frequency, and duration of PA in Chinese based on gender, age, and broad occupational categories and explored the potential effect between these factors and the common cold.ResultsApproximately 20.4% of participants reported not participating in sports regularly. Except for gender, there were significant differences in PA preference and intensity among the remaining individuals. However, intensity shows a U-shaped dose-response relationship with colds, whereas the frequency and duration have an inverse dose-response relationship. High intensity combined with high frequency increased colds the most. Nevertheless, non-exercise groups always have the most colds in each comparison.LimitationsThe result may be vulnerable to recall bias.ConclusionIntensity showed that U-shape, frequency, and duration showed inverse response to the number of colds last year, but age, sex, and occupation had no significant effects. High intensity and high frequency mixed increased colds the most, regardless of duration. (shrink)

A well established technique toward developing the proof theory of a Hilbert-style modal logic is to introduce a Gentzen-style equivalent (a Gentzenisation), then develop the proof theory of the latter, and finally transfer the metatheoretical results to the original logic (e.g., [1, 6, 8, 18, 10, 12]). In the first-order modal case, on one hand we know that the Gentzenisation of the straightforward first-order extension of GL, the logic QGL, admits no cut elimination (if the rule is included as primitive; (...) or, if not included, then the rule is not admissible [1]). On the other hand the (cut-free) Gentzenisations of the first-order modal logics M3 and ML3 of [10, 12] do have cut as an admissible rule. The syntactic cut admissibility proof given in [18] for the Gentzenisation of the propositional provability logic GL is extremely complex, and it was the basis of the proofs of cut admissibility of the Gentzenisations of M3 and ML3, where the presence of quantifiers and quantifier rules added to the complexity and length of the proof. A recent proof of cut admissibility in a cut-free Gentzenisation of GL is given in [5] and is quite short and easy to read. We adapt it here to revisit the proofs for the cases of M3 and ML3, resulting to similarly short and easy to read proofs, only slightly complicated by the presence of quantification and its relevant rules. (shrink)

Concerns with improper collection and usage of personal information by businesses or governments have been seen as critical to the success of the emerging electronic commerce. In this regard, computer professionals have the oversight responsibility for information privacy because they have the most extensive knowledge of their organization's systems and programs, as well as an intimate understanding of the data. Thus, the competence of these professionals in ensuring sound practice of information privacy is of great importance to both researchers and (...) practitioners. This research addresses the question of whether male computer professionals differ from their female counterparts in their self-regulatory efficacy to protect personal information privacy. A total of 103 male and 65 female subjects surveyed in Taiwan responded to a 10-item questionnaire that includes three measures: protection, non-distribution, and non-acquisition. The findings show significant gender differences exist in the subjects' overall self-regulatory efficacy for information privacy, and, in particular, that female subjects in this study exhibited a higher level of self-regulatory efficacy than males for the protection and non-acquisition of personal privacy information. The identification of the factorial structure of the self-regulatory efficacy concerning information privacy may contribute to future research directed to examining the links between privacy efficacy and psychological variables, such as ethical attitude, ethical intention, and self-esteem. Studies can also be extended to investigate how different cultural practices of morality and computer use in men and women may shape the different development patterns of privacy self-efficacy. Understanding the different cultural practices may then shed light on the social sources of privacy competence and the appropriate remedies that can be provided to improve the situation. (shrink)

This study aims to reveal patterns of e-petition co-signing behavior that are indicative of the political mobilization of online “communities”. We discuss the case of We the People, a US national experiment in the use of social media technology to enable users to propose and solicit support for policy suggestions to the White House. We apply Baumgartner and Jones's work on agenda setting and punctuated equilibrium, which suggests that policy issues may lie dormant for periods of time until some event (...) triggers attention from the media, interest groups, and elected representatives. In the case study presented, we focus on 21 petitions initiated during the week after the Sandy Hook shooting in opposition to gun control or in support of policy proposals that are alternatives to gun control, which we view as mobilized efforts to maintain stability and equilibrium in a policy system threatening to change. Using market basket analysis and social network analysis we found a core group of petitions in the “support law-abiding gun owners” theme that were highly connected and four “communities” of e-petitioners mobilizing in opposition to change in gun control policies and in favor of alternative proposals. (shrink)

The effect of authentic leadership and leader competency on employee job performance has received growing attention in the past decades; however, few studies have simultaneously integrated these two leadership perspectives. We have thus developed a mediated moderation model to test the interactive effect of authentic leadership and competency on followers’ job performance through work engagement. Based on a sample of 248 subordinate–supervisor pairs, hierarchical regression analyses reveal that authentic leadership positively relates to followers’ task performance and organizational citizenship behavior ; (...) leader competency moderates the relationship between authentic leadership and OCB; and followers’ work engagement mediates the main effect of authentic leadership and the interactive effect of authentic leadership and competency on followers’ task performance and OCB. All the three results are consistent with our hypotheses. (shrink)