In current dairy farming it is possible to run a profitable farm without having to adapt the system to the needs of dairy cows. In such systems the interests of the farmer and animals often diverge. Consequently, specific animal welfare problems occur. Foot disorders in dairy cattle are an illustrative example resulting from the specific methods of housing and management in current dairy farming. Foot disorders and the resulting lameness are considered the most important welfare problem in dairy farming. However, (...) these foot disorders not only typify welfare problems related to certain housing systems, but they also lead to the premature culling of cows. The assessment of the impact of foot disorders on the welfare of dairy cows raised the question of whether premature culling affects animal welfare since it affects the longevity of a cow. We argue that this aspect of longevity is morally relevant as an animal welfare issue. In this paper we aim to explore whether longevity is both (a) a morally relevant aspect in the discussion on killing animals and (b) a constitutive element of animal welfare. In other words, we aim to explore whether longevity is an independent moral argument in an animal welfare discussion. We claim that longevity is not merely important as an indicator of animal welfare, but is also a constitutive element of animal welfare. We argue that we need a more integrated approach to animal welfare and that an assessment that includes the aspect of time is necessary. This view involves a shift from views on animal welfare in terms of functioning or feeling well to a view on animal welfare that includes the aspect of natural living in which species-specific development is important. To show the impact of these points of view, we look at the practical implications for choices concerning the management of foot disorders in dairy cattle. (shrink)

Objectives To evaluate whether the requirement of “minimal risk and burden” for paediatric research without direct benefit to the subjects compromises the ability to obtain data necessary for improving paediatric care. To provide evidence-based reflections on the EU recommendation that allows for a higher level of risk. Design and setting Systematic analysis of the approval/rejection decisions made by the Dutch Central Committee on Research involving Human Subjects (CCMO). Review methods The analysis included 165 proposals for paediatric research without direct benefit (...) that were reviewed by the CCMO between January, 2000, and July, 2007. A separate, in-depth analysis of all drug studies included 18 early phase drug studies and nine other drug studies without direct benefit. Results 11 out of 165 studies were definitively rejected because the CCMO did not regard the risk and/or burden to be minimal. In three of these 11 cases (including two early phase drug studies) the requirement of minimal risk and burden was cited as the only reason for rejection. Four other early phase drug studies also involved risks and/or burdens that were not regarded to be minimal but were nevertheless approved. Conclusions The requirement of minimal risk and burden, aiming to protect research subjects, occasionally leads to rejection of protocols. Early phase drug studies relatively often do not comply with the requirement. Committees may find ways to approve important studies that formally should be rejected, but that is not a desirable solution. The regulatory framework should be revised to make such occasional exceptions to the requirement legitimate and transparent. (shrink)

A cross-cultural survey experiment revealed a dominant tendency to rely on a rule’s letter over its spirit when deciding which behaviors violate the rule. This tendency varied markedly across (k = 15) countries, owing to variation in the impact of moral appraisals on judgments of rule violation. Compared with laypeople, legal experts were more inclined to disregard their moral evaluations of the acts altogether and consequently exhibited stronger textualist tendencies. Finally, we evaluated a plausible mechanism for the emergence of textualism: (...) in a two-player coordination game, incentives to coordinate in the absence of communication reinforced participants’ adherence to rules’ literal meaning. Together, these studies (total n = 5,794) help clarify the origins and allure of textualism, especially in the law. Within heterogeneous communities in which members diverge in their moral appraisals involving a rule’s purpose, the rule’s literal meaning provides a clear focal point—an identifiable point of agreement enabling coordinated interpretation among citizens, lawmakers, and judges. (shrink)

The purpose of this paper is twofold: to comment on certain remarks of E. Koestermann, and to examine briefly some passages adduced by K. Wellesley as evidence for the alleged independence of the Leidensis . In a paper in CQ N.S. XV , 299–322, I attempted to demonstrate by various arguments that the readings of L are not such as to support the claim that this manuscript has authority independent of M. Those arguments may be summarized as follows: that the (...) majority of L's readings fall into a pattern of systematic normalization, that they give virtually no help in solving really deep corruptions, that L is particularly unreliable in transmitting proper names, that many readings of L show clear signs of being derived from M, that few of the good readings in L could not have been extracted from the corrupt text of M, and that other fifteenth-century manuscripts of Tacitus contain good corrections, not inferior to corrections found in L. No defender of L has yet, as far as I know, answered the arguments I put forward, and E. Koestermann has not even understood them, for he writes as follows : ‘[Goodyear] legt den Finger darauf, daß die abweichenden Lesarten in L in ihrer Diktion stärker ciceronischen Charakter tragen, demnach eher als Konjekturen zu verstehen seien. Aber dies Argument ist nicht durchschlagend, da die späteren Annalenbücher … eine gemässigtere Tendenz aufweisen und damit näher an Cicero heranrücken.’. (shrink)

This paper addresses the doubts voiced by Wigner about the physical relevance of the concept of geometrical points by exploiting some facts known to all but honored by none: Almost all real numbers are transcendental; the explicit representation of any one will require an infinite amount of physical resources. An instrument devised to measure a continuous real variable will need a continuum of internal states to achieve perfect resolution. Consequently, a laboratory instrument for measuring a continuous variable in a finite (...) time can report only a finite number of values, each of which is constrained to be a rational number. It does not matter whether the variable is classical or quantum-mechanical. Now, in von Neumann’s measurement theory (von Neumann, Mathematical Foundations of Quantum Mechanics, Princeton University Press, Princeton, [1955]), an operator A with a continuous spectrum—which has no eigenvectors—cannot be measured, but it can be approximated by operators with discrete spectra which are measurable. The measurable approximant F(A) is not canonically determined; it has to be chosen by the experimentalist. It is argued that this operator can always be chosen in such a way that Sewell’s results (Sewell in Rep. Math. Phys. 56: 271, [2005]; Sewell, Lecture given at the J.T. Lewis Memorial Conference, Dublin, [2005]) on the measurement of a hermitian operator on a finite-dimensional vector space (described in Sect. 3.2) constitute an adequate resolution of the measurement problem in this theory. From this follows our major conclusion, which is that the notion of a geometrical point is as meaningful in nonrelativistic quantum mechanics as it is in classical physics. It is necessary to be sensitive to the fact that there is a gap between theoretical and experimental physics, which reveals itself tellingly as an error inherent in the measurement of a continuous variable. (shrink)

Aristotle maintains that every man has, or should have, a single end, a target at which he aims. The doctrine is stated in E.N. I 2. ‘If, then, there is some end of the things we do which we desire for its own sake, and if we do not choose everything for the sake of something else, clearly this must be the good and the chief good. Will not the knowledge of it, then, have a great influence on life? Shall (...) we not, like archers who have a mark to aim t, be more likely to hit upon what is right?’. Aristotle does not here prove, nor need we understand him as claiming to prove, that there is only one end which is desired for itself. He points out correctly that, if there are objects which are desired but not desired for themselves, there must be some object which is desired for itself. The passage further suggests that, if there were one such object and one only, this fact would be important and helpful for the conduct of life. (shrink)