Results for 'Sophie Veigl'

999 found
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  1.  9
    A use/disuse paradigm for CRISPR-Cas systems.Sophie Juliane Veigl - 2019 - Biology and Philosophy 34 (1):13.
    In his insightful review, Eugene V. Koonin discusses various aspects of CRISPR-Cas systems with a strong focus on their qualities as "adaptive immune systems". The CRISPR-Cas system is most famous for its application as a gene-editing tool. Koonin provides a deeper insight into its biological function in bacteria, which is to immunize the cell against parasite DNA. I shall comment on one issue discussed in the text, in two steps. First, I shall elaborate on CRISPR-Cas systems and their supposed Lamarckian (...)
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  2.  19
    Do heritable immune responses extend physiological individuality?Sophie Juliane Veigl - 2022 - History and Philosophy of the Life Sciences 44 (4):1-20.
    Immunology and its philosophy are a primary source for thinking about biological individuality. Through its discriminatory function, the immune system is believed to delineate organism and environment within one generation, thus defining the physiological individual. Based on the paradigmatic instantiations of immune systems, immune interactions and, thus, the physiological individual are believed to last only for one generation. However, in recent years, transgenerationally persisting immune responses have been reported in several phyla, but the consequences for physiological individuality have not yet (...)
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  3.  26
    Adaptive immunity or evolutionary adaptation? Transgenerational immune systems at the crossroads.Sophie Juliane Veigl - 2022 - Biology and Philosophy 37 (5):1-21.
    In recent years, immune systems have sparked considerable interest within the philosophy of science. One issue that has received increased attention is whether other phyla besides vertebrates display an adaptive immune system. Particularly the discovery of CRISPR-Cas9-based systems has triggered a discussion about how to classify adaptive immune systems. One question that has not been addressed yet is the transgenerational aspect of the CRISPR-Cas9-based response. If immunity is acquired and inherited, how to distinguish evolutionary from immunological adaptation? To shed light (...)
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  4. Rethinking hereditary relations: the reconstitutor as the evolutionary unit of heredity.Sophie J. Veigl, Javier Suárez & Adrian Stencel - 2022 - Synthese 200 (5):1-42.
    This paper introduces the reconstitutor as a comprehensive unit of heredity within the context of evolutionary research. A reconstitutor is the structure resulting from a set of relationships between different elements or processes that are actively involved in the recreation of a specific phenotypic variant in each generation regardless of the biomolecular basis of the elements or whether they stand in a continuous line of ancestry. Firstly, we justify the necessity of introducing the reconstitutor by showing the limitations of other (...)
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  5.  23
    Small RNA research and the scientific repertoire: a tale about biochemistry and genetics, crops and worms, development and disease.Sophie Juliane Veigl - 2021 - History and Philosophy of the Life Sciences 43 (1):1-25.
    The discovery of RNA interference in 1998 has made a lasting impact on biological research. Identifying the regulatory role of small RNAs changed the modes of molecular biological inquiry as well as biologists' understanding of genetic regulation. This article examines the early years of small RNA biology's success story. I query which factors had to come together so that small RNA research came into life in the blink of an eye. I primarily look at scientific repertoires as facilitators of rapid (...)
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  6.  63
    Notes on a complicated relationship: scientific pluralism, epistemic relativism, and stances.Sophie Juliane Veigl - 2020 - Synthese 199 (1-2):3485-3503.
    While scientific pluralism enjoys widespread popularity within the philosophy of science, a related position, epistemic relativism, does not have much traction. Defenders of scientific pluralism, however, dread the question of whether scientific pluralism entails epistemic relativism. It is often argued that if a scientific pluralist accepts epistemic relativism, she will be unable to pass judgment because she believes that “anything goes”. In this article, I will show this concern to be unnecessary. I will also argue that common strategies to differentiate (...)
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  7.  7
    Seeing “Lamarckian” More Positively: The Use/Disuse Paradigm Increases Understanding.Sophie J. Veigl - 2019 - Bioessays 41 (6):1900054.
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  8.  37
    Teaching Biologists the Philosophy of Their Time.Sophie Juliane Veigl - 2021 - Acta Biotheoretica 69 (3):483-491.
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  9.  25
    Friedrich Miescher’s Discovery in the Historiography of Genetics: From Contamination to Confusion, from Nuclein to DNA.Sophie Juliane Veigl, Oren Harman & Ehud Lamm - 2020 - Journal of the History of Biology 53 (3):451-484.
    In 1869, Johann Friedrich Miescher discovered a new substance in the nucleus of living cells. The substance, which he called nuclein, is now known as DNA, yet both Miescher’s name and his theoretical ideas about nuclein are all but forgotten. This paper traces the trajectory of Miescher’s reception in the historiography of genetics. To his critics, Miescher was a “contaminator,” whose preparations were impure. Modern historians portrayed him as a “confuser,” whose misunderstandings delayed the development of molecular biology. Each of (...)
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  10.  25
    Towards a Politicized Anatomy of Fundamental Disagreement.Sophie Juliane Veigl - 2023 - International Journal of Philosophical Studies 31 (3):450-466.
    Fundamental disagreement is at the core of many debates surrounding epistemic relativism. Proponents of epistemic relativism argue that certain disagreements are irresolvable because proponents base their views on fundamentally different epistemic principles and, thus, fundamentally different epistemic systems. Critics of epistemic relativism argue that this analysis is wrong since the particular epistemic principles in question are most of the time derived from or instances of the same, more basic, epistemic principle. With regard to the individuation of epistemic systems, there is, (...)
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  11.  30
    What Counts as an Immune Response? On the Role of Abiotic Stress in Immunology.Sophie Juliane Veigl - 2023 - Biological Theory 18 (3):210-224.
    In the postgenomic era, interactions between organism and environment are central in disciplines such as epigenetics, medical physiology, and immunology. Particularly in the more "applied" medical fields, an emphasis lies on interactions of the organism with other organisms, that is, other living things. There is, however, a growing amount of research investigating the impact of abiotic triggers on the immune system. While the distinction between biota and abiota features heavily in other contexts, its status is not explicit within immunology. Do (...)
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  12.  33
    Scientific Pluralism in Practice: Responses to Anomaly in the Sciences.Sophie Juliane Veigl - 2022 - Philosophy, Theory, and Practice in Biology 14 (14).
    Scientific pluralism has become a household position within the philosophy of science literature. There are numerous accounts of plurality within various research fields. Most scientific pluralists, however, focus on the plurality of theories, explanations, or mechanisms, while other potential targets of plurality that the philosophy of scientific practice has particularly emphasized have so far not received extensive treatment. How should we approach such practice-based candidates of plurality? And what are potential pluralist positions concerning the objects of scientific practice? In this (...)
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  13. A Third Way to the Selected Effect/Causal Role Distinction in the Great Encode Debate.Ehud Lamm & Sophie Veigl - 2023 - Theoretical Biology Forum 2023 (1-2):53-74.
    Since the ENCODE project published its final results in a series of articles in 2012, there is no consensus on what its implications are. ENCODE’s central and most controversial claim was that there is essentially no junk DNA: most sections of the human genome believed to be «junk» are functional. This claim was met with many reservations. If researchers disagree about whether there is junk DNA, they have first to agree on a concept of function and how function, given a (...)
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  14.  69
    Back to Chromatin: ENCODE and the Dynamic Epigenome.Ehud Lamm & Sophie Juliane Veigl - 2022 - Biological Theory 17 (4):235-242.
    The “Encyclopedia of DNA Elements” (ENCODE) project was launched by the US National Human Genome Research Institute in the aftermath of the Human Genome Project (HGP). It aimed to systematically map the human transcriptome, and held the promise that identifying potential regulatory regions and transcription factor binding sites would help address some of the perplexing results of the HGP. Its initial results published in 2012 produced a flurry of high-impact publications as well as criticisms. Here we put the results of (...)
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  15.  12
    Teaching Biologists the Philosophy of Their Time: Kostas Kampourakis and Tobias Uller: Philosophy of Science for Biologists. Cambridge University Press, Cambridge, UK, 2020, 340pp, ISBN: 9781108740708. [REVIEW]Sophie Juliane Veigl - 2021 - Acta Biotheoretica 69 (3):483-491.
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  16. Philosophy of Science: A User's Guide.Adrian Currie & Sophie Veigl (eds.) - forthcoming - MIT Press.
    Thought experiments play a role in science and in some central parts of contemporary philosophy. They used to play a larger role in philosophy of science, but have been largely abandoned as part of the field’s “practice turn”. This chapter discusses possible roles for thought experimentation within a practice-oriented philosophy of science. Some of these roles are uncontroversial, such as exemplification and aiding discovery. A more controversial role is the reliance on thought experiments to justify philosophical claims. It is proposed (...)
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  17. Thought Experiments Repositioned.Adrian Currie & Sophie Veigl (eds.) - forthcoming
    Thought experiments play a role in science and in some central parts of contemporary philosophy. They used to play a larger role in philosophy of science, but have been largely abandoned as part of the field’s “practice turn”. This chapter discusses possible roles for thought experimentation within a practice-oriented philosophy of science. Some of these roles are uncontroversial, such as exemplification and aiding discovery. A more controversial role is the reliance on thought experiments to justify philosophical claims. It is proposed (...)
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  18. An Argument for Uniqueness About Evidential Support.Sinan Dogramaci & Sophie Horowitz - 2016 - Philosophical Issues 26 (1):130-147.
    White, Christensen, and Feldman have recently endorsed uniqueness, the thesis that given the same total evidence, two rational subjects cannot hold different views. Kelly, Schoenfield, and Meacham argue that White and others have at best only supported the weaker, merely intrapersonal view that, given the total evidence, there are no two views which a single rational agent could take. Here, we give a new argument for uniqueness, an argument with deliberate focus on the interpersonal element of the thesis. Our argument (...)
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  19.  87
    One or two? A Process View of pregnancy.Anne Sophie Meincke - 2022 - Philosophical Studies 179 (5):1495-1521.
    How many individuals are present where we see a pregnant individual? Within a substance ontological framework, there are exactly two possible answers to this question. The standard answer—two individuals—is typically championed by scholars endorsing the predominant Containment View of pregnancy, according to which the foetus resides in the gestating organism like in a container. The alternative answer—one individual—has recently found support in the Parthood View, according to which the foetus is a part of the gestating organism. Here I propose a (...)
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  20. Expecting the Unexpected.Tom Dougherty, Sophie Horowitz & Paulina Sliwa - 2015 - Res Philosophica 92 (2):301-321.
    In an influential paper, L. A. Paul argues that one cannot rationally decide whether to have children. In particular, she argues that such a decision is intractable for standard decision theory. Paul's central argument in this paper rests on the claim that becoming a parent is ``epistemically transformative''---prior to becoming a parent, it is impossible to know what being a parent is like. Paul argues that because parenting is epistemically transformative, one cannot estimate the values of the various outcomes of (...)
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  21.  19
    Body Boundary Work: Praxeological Thoughts on Personal Corporality.Tobias Boll & Sophie Merit Müller - 2020 - Human Studies 43 (4):585-602.
    In everyday life, we usually go by theone-body-one-person rule: one person has one body. This social belief builds on two assumptions: bodies are individual units and they are the same in different situations. This is also the conceptual resource for social theories that build on the notion of individuals. In this article, we turn it into a sociological topic. We develop a vocabulary for reconstructing bodily one-ness and bodily sameness as practically achieved social order, asbody boundary work: what belongs to (...)
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  22.  14
    A Critique of Olfactory Objects.Ann-Sophie Barwich - 2019 - Frontiers in Psychology 10.
    Does the sense of smell involve the perception of odor objects? General discussion of perceptual objecthood centers on three criteria: stimulus representation; perceptual constancy; and figure-ground segregation. These criteria, derived from theories of vision, have been applied to olfaction in recent philosophical debates about psychology. An inherent problem with such framing of olfactory objecthood is that philosophers explicitly ignore the constitutive factors of the sensory systems that underpin the implementation of these criteria. The biological basis of odor coding is fundamentally (...)
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  23.  40
    From Molecules to Perception: Philosophical Investigations of Smell.Ann-Sophie Barwich & Barry C. Smith - 2022 - Philosophy Compass 17 (11):e12883.
    Theories of perception have traditionally dismissed the sense of smell as a notoriously variable and highly subjective sense, mainly because it does not easily fit into accounts of perception based on visual experience. So far, philosophical questions about the objects of olfactory perception have started by considering the nature of olfactory experience. However, there is no philosophically neutral or agreed conception of olfactory experience: it all depends on what one thinks odors are. We examine the existing philosophical methodology for addressing (...)
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  24.  19
    Bending Molecules or Bending the Rules? The Application of Theoretical Models in Fragrance Chemistry.Ann-Sophie Barwich - 2015 - Perspectives on Science 23 (4):443-465.
    What does it take for a scientific model to represent? Scientific models have received a great deal of attention in recent philosophical literature. Following Morgan and Morrison’s account of “Models as Mediators”, analysis of how models represent has changed from questioning what properties of models can be said to correlate with the world to asking how models are used to relate to an intended target-system. This turn to a practice-oriented approach of understanding models was a response to a general philosophical (...)
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  25.  3
    III.—The Place of Experts in Democracy: A Symposium.Bosanquet Bernard, Bryant Sophie & G. E. T. Boss - 1909 - Proceedings of the Aristotelian Society 9 (1):61-84.
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  26.  2
    Commerce philosophique du grand siècle.Frédéric Brahami, Sophie-Anne Leterrier, Anne Auchatraire, Pierre Lurbe, Bruno Neveu & Simone Mazauric - 2001 - Revue de Synthèse 122 (2-4):674-688.
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  27.  6
    Sélection naturelle ou volonté de puissance : comment interpréter le processus de destruction créatrice?André Lapied & Sophie Swaton - 2013 - Revue de Philosophie Économique 14 (2):43-65.
    La délicate mise en rapport de la philosophie nietzschéenne et de l’économie est d’une pratique récente. Dans ce contexte, cet article est motivé par l’introduction du traitement nietzschéen de la « destruction créatrice » en économie et la manière de justifier philosophiquement cette référence. Pour cela, nous mettons en concurrence les interprétations évolutionnistes et nietzschéennes de la destruction créatrice. Ces deux métaphores nous semblent difficilement conciliables et nous avançons des arguments en faveur de la volonté de puissance, contre la lutte (...)
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  28.  19
    Fashion fades, Chanel No. 5 remains: Epistemology between Style and Technology.Ann-Sophie Barwich & Matthew Rodriguez - 2020 - Berichte Zur Wissenschaftsgeschichte 43 (3):367-384.
    Perfumes embody a chemical record of style and technology. Blurring the boundary between what counts as natural and artificial in both a material and a perceptual sense, perfumery presents us with a domain of multiple disciplinary identities relevant to social studies: art, craft, and techno‐science. Despite its profound impact as a cultural practice, perfume has seldom featured in historical scholarship. The reason for this neglect is its inherently qualitative dimension: perfume cannot be understood via codified representation but requires direct acquaintance (...)
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  29.  8
    Conscious Experience: a Logical Inquiry, by Anil Gupta: Harvard University Press, Cambridge, MA, 2019, 440 pages.Ann-Sophie Barwich - 2020 - Philosophia 48 (3):1255-1262.
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  30.  10
    A Computational Model of Working Memory Integrating Time-Based Decay and Interference.Benoît Lemaire & Sophie Portrat - 2018 - Frontiers in Psychology 9.
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  31.  11
    Personale Identität ohne Persönlichkeit? Anmerkungen zu einem vernachlässigten Zusammenhang.Anne Sophie Meincke - 2016 - Philosophisches Jahrbuch 123 (1):114-145.
    Recent decades have seen an increasing tendency to exclude the phenomenon of personality from the metaphysical investigation of personal identity. We are advised not to confuse personal identity as a philosophical subject, namely as the metaphysical issue of specifying what it is that makes a person staying numerically self-identical over time, with the psychological question of 'personal identity' which asks what makes someone the individual person they are with their particular character and history. However, one might be unsatisfied with this. (...)
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  32.  9
    Surface-Based Morphometry of Cortical Thickness and Surface Area Associated with Heschl's Gyri Duplications in 430 Healthy Volunteers.Damien Marie, Sophie Maingault, Fabrice Crivello, Bernard Mazoyer & Nathalie Tzourio-Mazoyer - 2016 - Frontiers in Human Neuroscience 10.
  33.  45
    The Next Generation Event Horizon Telescope Collaboration: History, Philosophy, and Culture.Peter Galison, Juliusz Doboszewski, Jamee Elder, Niels C. M. Martens, Abhay Ashtekar, Jonas Enander, Marie Gueguen, Elizabeth A. Kessler, Roberto Lalli, Martin Lesourd, Alexandru Marcoci, Sebastián Murgueitio Ramírez, Priyamvada Natarajan, James Nguyen, Luis Reyes-Galindo, Sophie Ritson, Mike D. Schneider, Emilie Skulberg, Helene Sorgner, Matthew Stanley, Ann C. Thresher, Jeroen Van Dongen, James Owen Weatherall, Jingyi Wu & Adrian Wüthrich - 2023 - Galaxies 11 (1):32.
    This white paper outlines the plans of the History Philosophy Culture Working Group of the Next Generation Event Horizon Telescope Collaboration.
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  34.  82
    Fostering Children’s Connection to Nature Through Authentic Situations: The Case of Saving Salamanders at School.Stephan Barthel, Sophie Belton, Christopher M. Raymond & Matteo Giusti - 2018 - Frontiers in Psychology 9:302887.
    The aim of this paper is to explore how children learn to form new relationships with nature. It draws on a longitudinal case study of children participating in a stewardship project involving the conservation of salamanders during the school day in Stockholm, Sweden. The qualitative method includes two waves of data collection: when a group of 10-year-old children participated in the project (2015) and two years after they participated (2017). We conducted 49 interviews with children as well as using participant (...)
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  35.  23
    Fishing for Genes: How the Largest Gene Family in the Mammalian Genome was Found.Ann-Sophie Barwich - 2021 - Perspectives on Science 29 (4):359-387.
    In 1991, Linda Buck and Richard Axel identified the multigene family expressing odor receptors. Their discovery transformed research on olfaction overnight, and Buck and Axel were awarded the 2004 Nobel Prize in Physiology or Medicine. Behind this success lies another, less visible study about the methodological ingenuity of Buck. This hidden tale holds the key to answering a fundamental question in discovery analysis: What makes specific discovery tools fit their tasks? Why do some strategies turn out to be more fruitful (...)
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  36.  8
    Esquisse d'un tableau historique des progrès de l'esprit humain.Jean-Antoine-Nicolas de Caritat Condorcet, P. Daunou & Marie-Louise-Sophie de Grouchy Condorcet - 1966 - Paris: Editions sociales. Edited by Monique Hincker & François Hincker.
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  37.  7
    Les fonctions maternelles dans l’accueil familial, regard clinique des visites médiatisées.Sophie Martins-Lima - 2021 - Dialogue: Families & Couples 234 (4):89-103.
    L’article présente la concordance et les accordages entre le travail processuel du psychologue en visite médiatisée et les fonctions maternelles assurées par l’assistant(e) familial(e) auprès de l’enfant accueilli. Dans une approche inter et transdisciplinaire garantie par un métacadre institutionnel sécurisant, le psychologue clinicien se trouve à l’articulation de ces instances complémentaires. Les enfants amenés à rencontrer leur(s) parent(s) en visite médiatisée se sont développés dans une famille aux liens pathologiques. Le clinicien vient assurer une fonction de moi-auxiliaire pour l’enfant, favorisant (...)
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  38.  6
    The Effects of Acute Moderate and High Intensity Exercise on Memory.David Marchant, Sophie Hampson, Lucy Finnigan, Kelly Marrin & Craig Thorley - 2020 - Frontiers in Psychology 11.
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  39.  8
    Being Easy to Communicate Might Make Verdicts Based on Confessions More Legitimate.Hugo Mercier, Anne-Sophie Hacquin & Nicolas Claidière - 2021 - Journal of Cognition and Culture 21 (3-4):203-225.
    In many judicial systems, confessions are a requirement for criminal conviction. Even if confessions are intrinsically convincing, this might not entirely explain why they play such a paramount role. In addition, it has been suggested that confessions owe their importance to their legitimizing role, explaining why they could be required even when other evidence has convinced a judge. But why would confessions be particularly suited to justify verdicts? One possibility is that they can be more easily transmitted from one individual (...)
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  40.  3
    Social Interventions Targeting Social Relations Among Older People at Nursing Homes: A Qualitative Synthesized Systematic Review.Anne Sophie Bech Mikkelsen, Signe Petersen, Anne Cathrine Dragsted & Maria Kristiansen - 2019 - Inquiry: The Journal of Health Care Organization, Provision, and Financing 56:004695801882392.
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  41.  9
    Apposition et métonymie adjectivales, figures d’une sous-énonciation?Sophie Milcent-Lawson - 2020 - Corela. Cognition, Représentation, Langage.
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  42.  3
    The Effect of Sleep on Children's Word Retention and Generalization.Emma L. Axelsson, Sophie E. Williams & Jessica S. Horst - 2016 - Frontiers in Psychology 7.
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  43.  7
    De la littérature à la philosophie.Fabienne-Sophie Chauderlot - 2000 - Bulletin de la Société Américaine de Philosophie de Langue Française 12 (1):50-77.
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  44.  14
    La mathématisation comme problème.Hugues Chabot & Sophie Roux (eds.) - 2011 - Paris (France): Édiitons des Archives contemporaines.
    L'histoire des sciences suffit à réfuter la thèse de la mathématisation impossible, selon laquelle la mathématisation procéderait d'un formalisme abstrait manquant les choses mêmes ou la spécificité d'un domaine d'objets. Cette histoire montre en effet qu'on n'a pas cessé de mathématiser des choses dont il avait été longtemps dit qu'elles devaient, étant donné leur nature, éternellement résister à la mathématisation. À la thèse de la mathématisation impossible, il est dès lors tentant d'opposer la thèse de la mathématisation inéluctable, selon laquelle (...)
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  45. Sola Fide - Lunther et l'Eglise (Et. d'hist, et de phil. rel. de ta faculté de théol. prot. de Strasbourg. Coll.Léon Chestov, Sophie Sève & R. Mehl - 1957 - Tijdschrift Voor Filosofie 19 (3):519-519.
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  46.  8
    Physics and Metaphysics in Descartes and in His Reception.Delphine Antoine-Mahut & Sophie Roux (eds.) - 2018 - New York: Routledge.
    This volume explores the relationship between physics and metaphysics in Descartes' philosophy. According to the standard account, Descartes modified the objects of metaphysics and physics and inverted the order in which these two disciplines were traditionally studied. This book challenges the standard account in which Descartes prioritizes metaphysics over physics. It does so by taking into consideration the historical reception of Descartes and the ways in which Descartes himself reacted to these receptions in his own lifetime. The book stresses the (...)
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  47.  2
    Éditorial. Les dispositifs de médiation pour les parents vulnérables.Didier Drieu & Sophie Gilbert - 2023 - Dialogue: Families & Couples 241 (3):15-19.
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  48. Rethinking the History of Logic, Mathematics, and Exact Sciences.Elena Ficara, Andrea Reichenberger & Anna-Sophie Heinemann (eds.) - forthcoming - Rickmansworth (Herts): College Publications.
     
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  49.  12
    Improving conservation outcomes in agricultural landscapes: farmer perceptions of native vegetation on the Yorke Peninsula, South Australia.Bianca Amato & Sophie Petit - 2023 - Agriculture and Human Values 40 (4):1537-1557.
    With agriculture the primary driver of biodiversity loss, farmers are increasingly expected to produce environmental outcomes and protect biodiversity. However, lack of attention to the way farmers perceive native vegetation has resulted in conservation targets not being met. The Yorke Peninsula (YP), South Australia, is an agricultural landscape where 50% farmers perceived that long-term planning was for ≤ 30 years, not enough time to promote ecosystem conservation; (5) a lack of natural resource management information for farmers—as a result, farmers relied (...)
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  50.  9
    VetiVoc: A modular ontology for the fashion, textile and clothing domain.Xavier Aimé, Sophie George & Jeremy Hornung - 2016 - Applied ontology 11 (1):1-28.
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