We describe a set of two computer‐implemented models that solve physics problems in ways characteristic of more and less competent human solvers. The main features accounting for different competences are differences in strategy for selecting physics principles, and differences in the degree of automation in the process of applying a single principle. The models provide a good account of the order in which principles are applied by human solvers working problems in kinematics and dynamics. They also are sufficiently flexible to (...) allow easy extension to several related domains of physics problems. (shrink)

This is an extensive anthology of the writings of John Dewey, edited by John J. McDermott.

Genetic testing has historically been performed in the context of chronic disease and cancer diagnostics. The timelines for these tests are typically measured in days or weeks, rather than in minutes. As such, the concept that genetic information might be generated and then used to alter management in the acute setting has, thus far, not been feasible. However, recent advances in genetic technologies have the potential to allow genetic information to be generated significantly quicker. The m.1555A>G genetic variant is present (...) in one in 500 individuals and predisposes to profound hearing loss following the administration of aminoglycoside antibiotics. These antibiotics are used frequently in cases of neonatal sepsis and it is estimated that approximately 180 neonates in the UK are at risk of antibiotic induced hearing loss each year because of this genetic change. Knowledge of this variant in the acute setting would allow clinicians to prescribe alternative antibiotics. The Pharmacogenetics to Avoid Loss of Hearing study will implement a genetic point of care test for the m.1555A>G variant within two major UK based neonatal intensive care units. This represents the first trial of a genetic POCT aimed at altering management in the acute setting. This round table discussion outlines the novel ethical issues faced in the development of this trial and the legal barriers to implementation. We ask five stakeholders to provide their opinions on this trial and their perspectives on the concept of genetic testing in the acute setting.Trial registration numberISRCTN-13704894. (shrink)

In his introduction to this collection, John representative. McDermott presents James's thinking in all its manifestations, stressing the importance of radical empiricism and placing into perspective the doctrines of pragmatism and the will to believe. The critical periods of James's life are highlighted to illuminate the development of his philosophical and psychological thought. The anthology features representive selections from _The Principles of Psychology, The Will to Believe_, and _The Variety of Religious Experience_ in addition to the complete _Essays in Radical (...) Empiricism_ and _A Pluralistic Universe_. The original 1907 edition of _Pragmatism_ is included, as well as classic selections from all of James's other major works. Of particular significance for James scholarship is the supplemented version of Ralph Barton Perry's _Annotated Bibliography of the Writings of William James_, with additions bringing it up to 1976. (shrink)

This book traces the trajectory of John J. McDermott’s philosophical career through a selection of his essays. Many were originally occasional pieces and address specific issues in American thought and culture. Together they constitute a mosaic of McDermott’s philosophy, showing its roots in an American conception of experience. Though he draws heavily on the thought of William James and the pragmatists, McDermott has his own unique perspective on philosophy and American life. He presents this to the reader in exquisitely crafted (...) prose. Drawing inspiration from American history, from existentialist themes, and from personal experiences, he offers a dramatic consideration of our culture’s failures and successes.McDermott crosses disciplinary boundaries to draw on whatever works to help make sense of theissues with which he is dealing—issues rooted in medical practice, political events, pedagogical habits, and the worlds of the arts. His work thus resists simple categorization. It is precisely this that makes his vibrant prose appealing to so many both inside and outside the world of American philosophy. (shrink)

Now back in print, and in paperback, these two classic volumes illustrate the scope and quality of Royce'sthought, providing the most comprehensive selection ofhis writings currently available. They offer a detailedpresentation of the viable relationship Royce forgedbetween the local experience of community and thedemands of a philosophical and scientific vision ofthe human situation.The selections reprinted here are basic to any understandingof Royce's thought and its pressing relevanceto contemporary cultural, moral, and religious issues.

De Lubac a sans doute emprunté beaucoup à Rousselot. A côté du désir naturel de la vision béatifique, Rousselot postulait une compréhension plus statique de la nature, représentée par un «Adam primordial», comme fondement de la connaissance conceptuelle. Tout en ignorant l'«Adam primordial» et rejetant l'«ordre naturel possible» de Rousselot, de Lubac a développé une double notion de nature comme dynamisme nécessaire et libre. A cela correspond sa compréhension du surnaturel comme à la fois exigence humaine et don libre de (...) Dieu. Une connaissance naturelle conceptuelle du Dieu inconnaissable est également nécessaire pour fonder la liberté de l'homme devant l'offre surnaturelle de Dieu. Cependant, un tel ordre conceptuel, même relatif, reconduit de Lubac à Rousselot : ou bien la possibilité d'une béatitude naturelle, ou bien, avec le Rousselot plus tardif, une compréhension de la personne comme Action-Pensée au-delà des polarités paradoxales de la nature, qui offrent un eventail de choix possibles. Selon cette dernière vision le «surnaturel» est défini d'abord comme nouveauté historique en contraste avec la création, qui inclut liberté aussi bien que nature. (shrink)

What I say here has been said before on many days and nights by reflective persons, for centuries long and planetary wide. Why, then, say it again, Sam? Is it because Heraclitus was onto something when he told us the Logos speaks but few hear? Or is the situation that of the Hassidic tale as recounted by Martin Buber? A man took it upon himself to convey the message of the high and holy one. He found no response and so (...) went directly, petulantly, to the author of the message. "Why are you here?" asked the high and holy one. "I have offered your message and no one hears me." "But," comes the response, "there is no hearing here for you. I have sunk my hearing in the deafness of mortals." More directly we can recall .. (shrink)

We thank Parker and Wright for engaging in this roundtable debate in such a spirited way. The ‘Pharmacogenetic [test] to Avoid Loss of Hearing’ Trial is the first time a genetic point of care test has been applied in the acute neonatal setting; therefore, it is not surprising that questions have been raised which require debate, discussion and clarification. Parker and Wright misattribute several assumptions to the roundtable authors, which we would like to clarify here. Since they raise wider questions (...) about the PALOH trial itself, several of the roundtable discussants have made a joint response. (shrink)