The last two decades have witnessed a modest revival of scholarly interest in the writings of Max Stirner, a contemporary of Marx and probably the most radical of the Young Hegelians. Not unpredictably, there are many different interpretations of Stirner’s ideas being offered; this diversity may, as Lawrence Stepelevich notes, “be provoked by any number of real or imagined connections with whatever or whomever is of current concern.” There are, in fact, many voices speaking out of the pages of The (...) Ego and Its Own and many subtle twistings in the complex line of inquiry that Stirner follows, so it is not altogether surprising that commentators differ on its meaning and significance. However, much of the secondary literature on Stirner has given a jaundiced view of his ideas, has been one-sided and partial, because it has failed to ask the right questions with regard to his central argument. Stirner takes his readers on a rigorous intellectual journey toward a confrontation with the most basic questions of ontology and axiology; in answer to them he offers a process theory of the self and a radically contingent view of moral choice, which have certain implications for political practice. A reconsideration of Stirner’s ideas is worthwhile in order to sort through the different voices and reconstruct the vision of the self and values that lie at the heart of his argument. (shrink)

Printers and presses were central to the physical and social reproduction of the classical anarchist movement from the Paris Commune to the Second World War. Anarchists produced an environment rich in printed words by creating and circulating hundreds of journals, books, and pamphlets in dozens of languages. While some scholars and activists have examined the content of these publications, little attention has been paid to the printing process, the physical infrastructure and bodily practices producing and circulating this remarkable outpouring of (...) radical public speech. This paper brings the resources of the new materialism into conversation with the networks of anarchist printers and presses. Printers and presses operated as nodal points, horizontal linkages among the objects, persons, desires, and ideas constituting anarchist assemblages. In their publishing practices, anarchists may have implicitly identified a constitutive condition of possibility for the flourishing of radical political communities in our time as well as theirs. (shrink)

Anarchism is a fertile site for nurturing the sorts of encounters that feminists have called intersectionality. Anarchism and intersectionality share the goal of critically examining familiar as well as emergent flows of power and meaning, and understanding their relations to one another. This paper focuses on three compelling directions for anarchist studies: Indigenous anarchism, anarchism developing with new materialism, and anarchism emergent in radical book arts. Each thread has established roots while also moving in new directions. Anarchist encounters with Indigeneity, (...) new materialism, and book arts resonate with each other: they can foster “a commitment to the particular” through which we can immerse ourselves in rich and dense worlds where specific Indigenous theories and practices, detailed encounters with non-human things, and particular artistic + intellectual productions of materials can emerge. (shrink)

Government, media, and medical accounts of Emma Goldman converged to create her public presence in the U.S. as a "dangerous individual." The prevailing discourses constituted Goldman as violent, utilizing her alleged menace to distract attention from far more egregious violence against labor by state and corporate forces. Goldman responded by denying, confronting, and redirecting the alarmed gaze toward greater risks left underarticulated in hegemonic accounts. Goldman's bold confrontations with authorities constituted a kind of anarchist parrhesia, fearless speech, a relentless truth-telling (...) practice that risked her own security in pursuit of her "beautiful ideal." The labor of remembering America's history of class violence hones our attention to the complex discursive processes by which some historical facts come to count in prevailing narratives, while others fade into obscurity. (shrink)

Anarchists and homosexuals have periodically occupied similar positions in relation to US laws and policies: both have functioned as the needed outside against which the proper inside of political order can be established and maintained. Both have blurred the relation of words to deeds, speaking words that are forbidden because the words themselves are seen as dangerous deeds. Examining the deportation case of anarchist John Turner in 1903 and the 1993 Pentagon ban on homosexuals serving openly in the military, and (...) utilizing the intellectual tools provided by Judith Butler in her analysis of speech acts, this article investigates the process of criminalizing an identity category as well as the political context from which that criminalization can be challenged. My goals are to make use of Butler’s arguments about insurrectionary speech to understand anarchism’s historical role in the American political imaginary, and to supplement Butler’s analysis with greater attention to the histories of anarchist struggle. (shrink)

This essay turns to ancient sources in order to rethink the relationship between political apathy and democracy. If modern democratic theorists place political apathy entirely outside of democracy – either as a destructive limit upon the full realization of a democratic polity, or, more sanguinely, as a pragmatic necessity which tempers democracy so that it may function in a workable yet watered-down form – the ancients conceived of political apathy as a peculiarly democratic phenomenon that was likely to flourish in (...) tandem with the expansion of egalitarian institutional structures and moral ideas. Evidence for the ancient recognition of political apathy as a uniquely democratic kind of affliction centers on, but is not limited to, three main sources. In literature, the Homeric epic, and specifically the story of Achilles, present apathy for politics and commitment to human equality as synonymous forces. In philosophy, one of the main reasons Plato opposes the democratic regime is precisely that it engenders apathy among the citizenry. And in history, Herodotus’ account of the first debate on constitutions as well as the ancient democratic practice of election by lot reveal an ancient egalitarian interest in using democracy to quell, rather than encourage, political behavior. (shrink)

Although the primary meaning of Max Weber’s concept of disenchantment is as a sociological condition (the retreat of magic and myth from social life through processes of secularization and rationalization), as Weber himself makes clear in his address, “Science as a Vocation,” disenchantment can also be a philosophical act: an unusual form of moral discourse that derives new ethical direction out of the very untenability of a previously robust moral tradition. The philosophical variant of disenchantment is significant both because it (...) contradicts numerous elements of the sociological version and because it suggests there are forms of cognition unique to moral philosophy (insofar as the derivation of a moral teaching from the very absence of one is foreign to both a religious and ascientific mindset). (shrink)

The origin of insulin‐expressing β‐cells in the adult mammalian pancreas is controversial. During normal tissue turnover and following injury, β‐cells may be replaced by duplication of existing β‐cells.1 However, an alternative source of β‐cells has recently been proposed based on neogenesis from a Ngn3‐positive population present in regenerating pancreatic ducts.2 The appearance of β‐cells from Ngn3‐positive progenitors is reminiscent of normal pancreas development, and Ngn3‐expressing cells isolated from regenerating pancreas can generate the full repertoire of endocrine phenotypes. The isolation and (...) characterisation of the equivalent human progenitors may represent a significant step forward in the hunt for a cure for diabetes. BioEssays 30:617–620, 2008. © 2008 Wiley Periodicals, Inc. (shrink)

The US neutrino community gathered at the Workshop on the Intermediate Neutrino Program at Brookhaven National Laboratory February 4-6, 2015 to explore opportunities in neutrino physics over the next five to ten years. Scientists from particle, astroparticle and nuclear physics participated in the workshop. The workshop examined promising opportunities for neutrino physics in the intermediate term, including possible new small to mid-scale experiments, US contributions to large experiments, upgrades to existing experiments, R&D plans and theory. The workshop was organized into (...) two sets of parallel working group sessions, divided by physics topics and technology. Physics working groups covered topics on Sterile Neutrinos, Neutrino Mixing, Neutrino Interactions, Neutrino Properties and Astrophysical Neutrinos. Technology sessions were organized into Theory, Short-Baseline Accelerator Neutrinos, Reactor Neutrinos, Detector R&D and Source, Cyclotron and Meson Decay at Rest sessions.This report summarizes discussion and conclusions from the workshop. (shrink)

To localize wheat ESTs on chromosomes, 882 homoeologous group 6-specific ESTs were identified by physically mapping 7965 singletons from 37 cDNA libraries on 146 chromosome, arm, and sub-arm aneuploid and deletion stocks. The 882 ESTs were physically mapped to 25 regions flanked by 23 deletion breakpoints. Of the 5154 restriction fragments detected by 882 ESTs, 2043 were localized to group 6 chromosomes and 806 were mapped on other chromosome groups. The number of loci mapped was greatest on chromosome 6B and (...) least on 6D. The 264 ESTs that detected orthologous loci on all three homoeologs using one restriction enzyme were used to construct a consensus physical map. The physical distribution of ESTs was uneven on chromosomes with a tendency toward higher densities in the distal halves of chromosome arms. About 43% of the wheat group 6 ESTs identified rice homologs upon comparisons of genome sequences. Fifty-eight percent of these ESTs were present on rice chromosome 2 and the remaining were on other rice chromosomes. Even within the group 6 bins, rice chromosomal blocks identified by 1-6 wheat ESTs were homologous to up to 11 rice chromosomes. These rice-block contigs were used to resolve the order of wheat ESTs within each bin. (shrink)

The complex hexaploid wheat genome offers many challenges for genomics research. Expressed sequence tags facilitate the analysis of gene-coding regions and provide a rich source of molecular markers for mapping and comparison with model organisms. The objectives of this study were to construct a high-density EST chromosome bin map of wheat homoeologous group 2 chromosomes to determine the distribution of ESTs, construct a consensus map of group 2 ESTs, investigate synteny, examine patterns of duplication, and assess the colinearity with rice (...) of ESTs assigned to the group 2 consensus bin map. A total of 2600 loci generated from 1110 ESTs were mapped to group 2 chromosomes by Southern hybridization onto wheat aneuploid chromosome and deletion stocks. A consensus map was constructed of 552 ESTs mapping to more than one group 2 chromosome. Regions of high gene density in distal bins and low gene density in proximal bins were found. Two interstitial gene-rich islands flanked by relatively gene-poor regions on both the short and long arms and having good synteny with rice were discovered. The map locations of two ESTs indicated the possible presence of a small pericentric inversion on chromosome 2B. Wheat chromosome group 2 was shown to share syntenous blocks with rice chromosomes 4 and 7. (shrink)

Beginning with an examination of the relationship between Hegel and Goethe, Löwith discusses how Hegel's students, particularly Marx and Kierkegaard, interpreted--or reinterpreted--their master's thought, and proceeds with an in-depth assessment of the other important philosophers, from Feuerbach, Stirner, and Schelling to Nietzsche.

One of the central issue of developmental biology concerns the molecular mechanisms whereby a multipotent cell gives rise to distinct differentiated progeny. Differences between specialised cell types reflect variations in their patterns of gene expression. The regulation of transcription initiation is an important control point for gene expression and it is, therefore, not surprising that transcription factors play a pivotal role in mammalian development and differentiation.Haemopoiesis offers a uniquely tractable system for the study of lineage commitment and differentiation. The importance (...) of transcription factor in the normal regulation of haemopoiesis is underlined by the frequency with which transcription factors are targeted by leukaemogenic mutations. Studies of the function and regulation of haemopoietic transcription factors, especially those expressed in lineage‐restricted patterns, should greatly increase our understanding of the molecular control of haemopoiesis. In this review we have focused on insights provided by recent studies of the GATA and SCL proteins. (shrink)