This work presents results of improvement in the productivity of Arthrospira platensis in a company dedicated to its production. The six sigma methodology was applied in production processes that require the use of bioreactors. Starting from the analysis of the current state, aspects, physical and chemical variables that directly influence the productivity achieved were identified. Various culture media were tested and subsequently scaled for industrial production. In addition, the incorporation of carbon into the culture medium was controlled, optimizing the range (...) of potential hydrogen pH. The identified parameters were measured and six sigma methodology strategies were assigned. An improvement in productivity corresponding to 66% was verified with the same quality of final product. Keywords: Six sigma, Bioreactors, Productivity, Arthrospira platensis. References [1]E. Ariawan and A. Makalew, “Smart Micro Farm: Sustainable Algae Spirulina Growth Monitoring System” in 10th International Conference on Information Technology and Electrical Engineering, Bali, 2018, pp.1-4. [2]L. Socconini and C. Reato, Lean six sigma: sistema de gestión para liderar empresas. Primera edición. Barcelona: Marge Books, 2019. [3]H. Gutiérrez, Calidad and productividad. Cuarta edición. México D.F.: McGraw-Hill Interamericana, 2014. [4]G. Usharani, P. Saranraj and D. Kanchana, “Spirulina Cultivation: A Review” in International Journal of Pharmaceutical & Biological Archives, vol. 3, no. 6, pp. 1327-1336, December 2012. [5]J. Udin, O. Gani, A. Mahato, I. Sakib and M. Rakiuzzaman, SPIRULINA PRODUCTION IN DIFFERENT PHOTOBIOREACTORS ON ROOFTOP, International Journal of Business, Social and Scientific Research, vol. 8, no. 1, pp. 15-19, January 2020. [6]M. Arredondo, Contabilidad y análisis de costos. Primera edición. México D.F.: Grupo Editorial Patria, 2015. [7]J. García, Contabilidad de costos. Cuarta edición. México D.F.: McGraw-Hill Interamericana, 2014. [8]L. Socconini, Certificación Lean Six Sigma Green Belt para la excelencia en los negocios. Primera edición. Barcelona: Marge Books, 2015. [9]A. Vian, Introducción a la Química Industrial. Segunda edición. Buenos Aires: Reverté, 2012. [10]S. Milton, Estadística para Biología y Ciencias de la Salud. Tercera edición. Madrid: McGraw-Hill Interamericana, 2014. (shrink)

En este trabajo se presenta una comparación de los tiempos de respuesta, optimización de la ruta y complejidad del grafo en métodos de planificación de trayectoria para robots móviles autónomos. Se contrastan los desarrollos de Voronoi, Campos potenciales, Roadmap probabilístico y Descomposición en celdas para la navegación en un mismo entorno y validándolos para un número variable de obstáculos. Las evaluaciones demuestran que el método de generación de trayectoria por Campos Potenciales, mejora la navegación respecto de la menor ruta obtenida, (...) el método Rapidly Random Tree genera los grafos de menor complejidad y el método Descomposición en celdas, se desempeña con menor tiempo de respuesta y menor coste computacional. Palabras Clave: optimización, trayectoria, métodos de planificación, robots móviles. Referencias [1]H. Ajeil, K. Ibraheem, A. Sahib y J. Humaidi, “Multi-objective path planning of an autonomous mobile robot using hybrid PSO-MFB optimization algorithm, ” Applied Soft Computing, vol. 89, April 2020. [2]K.Patle, G. Babu, A. Pandey, D.R.K. Parhi y A. Jagadeesh, “A review: On path planning strategies for navigation of mobile robot,” Defence Technology, vol. 15, pp. 582-606, August 2019. [3]T. Mack, C. Copot, D. Trung y R. De Keyser, “Heuristic approaches in robot path planning: A survey,” Robotics and Autonomous Systems, vol. 86, pp. 13-28, December 2016. [4]L. Zhang, Z. Lin, J. Wang y B. He, “Rapidly-exploring Random Trees multi-robot map exploration under optimization framework,” Robotics and Autonomous Systems, vol. 131, 2020. [5]S. Khan y M. K. Ahmmed, "Where am I? Autonomous navigation system of a mobile robot in an unknown environment," 2016 5th International Conference on Informatics, Electronics and Vision, pp. 56-61, December 2016. [6]V. Castro, J. P. Neira, C. L. Rueda, J. C. Villamizar y L. Angel, "Autonomous Navigation Strategies for Mobile Robots using a Probabilistic Neural Network," IECON 2007 - 33rd Annual Conference of the IEEE Industrial Electronics Society, pp. 2795-2800, Taipei, 2007. [7]Y. Li, W. Wei, Y. Gao, D. Wang y C. Fan, “PQ-RRT*: An improved path planning algorithm for mobile robots,” Expert Systems with Applications, vol. 152, August 2020. [8]A. Muñoz, “Generación global de trayectorias para robots móviles, basada en curvas betaspline,” Dep. Ingeniería de Sistemas y Automática Escuela Técnica Superior de Ingeniería Universidad de Sevilla, 2014. [9]H. Montiel, E. Jacinto y H. Martínez, “Generación de Ruta Óptima para Robots Móviles a Partir de Segmentación de Imágenes,” Información Tecnológica, vol. 26, 2015. [10] C. Expósito, “Los diagramas de Vornooi, la forma matemática de dividir el mundo,” Dialnet, Diciembre 2016. (shrink)

Michel Foucault had a great influence upon a wide range of disciplines, and his work has been widely interpreted and is frequently referred to, but it is often difficult for beginners to find their way into the complexities of his thought. This is especially true for readers whose background is Anglo-American or "analytic" philosophy. C. G. Prado argues in this updated introduction that the time is overdue for Anglo-American philosophers to avail themselves of what Foucault offers. In this clear and (...) greatly-revised second edition, Prado focuses on Foucault's "middle" or genealogical work, particularly Discipline and Punish and Volume One of The History of Sexuality, in which Foucault most clearly comes to grips with the historicization of truth and knowledge and the formation of subjectivity. Understanding Foucault's thought on these difficult subjects requires working through much complexity and ambiguity, and Prado's direct and accessible introduction is the ideal place to start. (shrink)

BackgroundInstitutional review boards (IRBs) are formally designated to review, approve, and monitor biomedical research. They are responsible for ensuring that researchers comply with the ethical guidelines concerning human research participants. Given that IRBs might face different obstacles that cause delays in their processes or conflicts with investigators, this study aims to report the functions, roles, resources, and review process of IRBs in Saudi Arabia.MethodThis was a cross-sectional self-reported survey conducted from March 2021 to March 2022. The survey was sent to (...) 53 IRB chairpersons and the administration directors (or secretary) across the country through email after receiving verbal consent. The validated survey consisted of eight aspects: (a) organizational aspects, (b) membership and educational training, (c) submission arrangements and materials, (d) minutes, (e) review procedures, (f) communicating a decision, (g) continuing review, and (h) research ethics committee (REC) resources. A total of 200 points indicated optimal IRB functions.ResultsTwenty-six IRBs across Saudi Arabia responded to the survey. Overall, the IRBs in this study scored a total of 150/200 of the points on the self-assessment tool. Relatively newer IRBs (established less than ten years ago) conducted meetings at least once in a month, had annual funding, had more balanced gender representation, tended to score higher than older IRBs. The organizational aspect score was the lowest among all items in the survey (14.3 score difference, p-value < 0.01). The average turnaround time for expedited research from proposal submission to final decision was 7 days, while it was 20.5 days for the full committee review.ConclusionSaudi IRBs performed generally well. However, there is room for focused improvement with respect to extra resources and organizational issues that require closer evaluation and guidance from the regulatory bodies. (shrink)

This book examines the reactions of the friends and family of those who elect to die due to terminal illness. These surviving spouses, partners, relatives and friends, in addition to coping with the death of a loved one, must also deal with the loved one's decision to die, thus severing the relationship. C. G. Prado examines how reactions to elective death are influenced by cultural influences and beliefs, particularly those related to life, death and the possibility of an afterlife. Understanding (...) the role of these cultural influences on the grieving processes of survivors is a crucial step in allowing them to accept both intellectually and emotionally the finality of elective death and to deal with the decision of their loved one. (shrink)

This book is parapsychological study of the meaningful coincidence of events, extrasensory perception, and similar phenomena.

The concept of 'Archteypes' and the hypothesis of 'A Collective Unconscious' are two of Jung's better known and most exciting ideas. In this volume - taken from the Collected Works and appearing in paperback for the first time - Jung describes and elaborates the two concepts. Three essays establish the theoretical basis which are then followed by essays on specific archetypes. The relation of these to the process of individuation is examined in the last section. _The Archetypes and the Collective (...) Unconscious_ is one of Jung's central works. There are many illustrations in full colour. (shrink)

"From The collected works of C.G. Jung, volumes 4, 8, 12, 16"--P. [i].

_Psychological Types_ is one of Jung's most important and most famous works. First published by Routledge in the early 1920s it appeared after Jung's so-called fallow period, during which he published little, and it is perhaps the first significant book to appear after his own confrontation with the unconscious. It is the book that introduced the world to the terms 'extravert' and 'introvert'. Though very much associated with the unconscious, in _Psychological Types_ Jung shows himself to be a supreme theorist (...) of the conscious. In putting forward his system of psychological types Jung provides a means for understanding ourselves and the world around us: our different patterns of behaviour, our relationships, marriage, national and international conflict, organizational functioning. Appearing in paperback for the first time this central volume from Jung's Collected Works will be essential to anyone requiring a proper understanding of Jung's psychology. (shrink)

Concern with elective-death decisions usually focuses on individuals' competence and understanding of their situations and prospects. If problematic influences on individuals are considered, they almost invariably have to do with matters such as depression and the effects of medication. Too little attention is paid to how individuals, as subjects, are products of both external cultural and social influences on them, and of internal efforts and needs that determine their subjectivity.

Reprint. Originally published: 1959; 1st Princeton/Bollingen pbk. ed. published: 1970.

PREFATORY REMARKS T„ his book is about an enterprise which Plato (428— BC) saw as a holy quest and Friedrich Wil- helm Nietzsche (1844—1900) saw as a ...

We consider the astrophysical and cosmological implications of the existence of a minimum density and mass due to the presence of the cosmological constant. If there is a minimum length in nature, then there is an absolute minimum mass corresponding to a hypothetical particle with radius of the order of the Planck length. On the other hand, quantum mechanical considerations suggest a different minimum mass. These particles associated with the dark energy can be interpreted as the “quanta” of the cosmological (...) constant. We study the possibility that these particles can form stable stellar-type configurations through gravitational condensation, and their Jeans and Chandrasekhar masses are estimated. From the requirement of the energetic stability of the minimum density configuration on a macroscopic scale one obtains a mass of the order of 1055 g, of the same order of magnitude as the mass of the universe. This mass can also be interpreted as the Jeans mass of the dark energy fluid. Furthermore we present a representation of the cosmological constant and of the total mass of the universe in terms of ‘classical’ fundamental constants. (shrink)

Recently, Brukner and Zeilinger (Phys. Rev. Lett. 83(17) (2001) 3354) have claimed that the Shannon information is not well defined as a measure of information in quantum mechanics, adducing arguments that seek to show that it is inextricably tied to classical notions of measurement. It is shown here that these arguments do not succeed: the Shannon information does not have problematic ties to classical concepts. In a further argument, Brukner and Zeilinger compare the Shannon information unfavourably to their preferred information (...) measure, I(p), with regard to the definition of a notion of ''total information content.'' This argument is found unconvincing and the relationship between individual measures of information and notions of ''total information content'' investigated. We close by considering the prospects of Zeilinger's Foundational Principle as a foundational principle for quantum mechanics. (shrink)

Contents: Mandalas. I. A Study in the Process of Individuation. II. Concerning Mandala Symbolism Index Originally published in 1972. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in (...) the thousands of books published by Princeton University Press since its founding in 1905. (shrink)

In the 1950s and 60s, H. L. A. Hart's writings were responsible for the revitalizing of legal philosophy in the UK and worldwide. This new collection of essays by distinguished philosophers and legal theorists addresses the enduring significance of Hart's work, focusing upon some of its more neglected aspects, including his work on causation and the philosophy of action. Two essays discuss Hart and Honore;'s Causation in the Law, a book that has been undeservedly overlooked in many philosophical discussions of (...) causation. The majority of the essays consider Hart's views on the justification of punishment. They discuss Hart's dislike of retribution, his claim that harmless immorality should not be punished, and his search for a non-retributivist theory of mens rea and excuses. Other topics examined include Hart's definitions of key legal and philosophical concepts, including 'punishment', 'responsibility' and 'voluntariness', and his views on punishing negligent acts. (shrink)

According to Jonathan Lowe's ‘Personal Agency’, free actions begin with a volition or act of will, which is itself a freely performed action. However, Lowe's explanation of why volitions are free actions is viciously circular: he argues that volitions qualify as free actions because they are rationally explicable, but claims that an action can only be rationally explicable if it is freely performed.