Brain imaging studies have consistently shown subgenual Anterior Cingulate Cortical (sgACC) involvement in emotion processing. COMT Val158 and Met158 polymorphisms may influence such emotional brain processes in specific ways. Given that resting-state fMRI (rsfMRI) may increase our understanding on brain functioning, we integrated genetic and rsfMRI data and focused on sgACC functional connections. No studies have yet investigated the influence of the COMT Val158Met polymorphism (rs4680) on sgACC resting-state functional connectivity (rsFC) in healthy individuals. A homogeneous group of sixty-one Caucasian (...) right-handed healthy female university students, all within the same age range, underwent rsfMRI. Compared to Met158 homozygotes, Val158 allele carriers displayed significantly stronger rsFC between the sgACC and the left parahippocampal gyrus, ventromedial parts of the inferior frontal gyrus, and the nucleus accumbens (NAc). On the other hand, compared to Val158 homozygotes, we found in Met158 allele carriers stronger sgACC rsFC with the medial frontal gyrus, more in particular the anterior parts of the medial orbitofrontal cortex. Although we did not use emotional or cognitive tasks, our sgACC rsFC results point to possible distinct differences in emotional and cognitive processes between Val158 and Met158 allele carriers. However, the exact nature of these directions remains to be determined. (shrink)

In this study of the cognitive paradigm, De Mey applies the study of computer models of human perception to the philosophy and sociology of science. "A most stimulating, and intellectually delightful book."--John Goldsmith "[De Mey] has brought together an unusually wide range of material, and suggested some interesting lines of thought, about what should be an important application of cognitive science: The understanding of science itself."-- Cognition and Brain Theory "It ought to be on the shelf of every teacher and (...) researcher in the field and on the reading list of any student or practitioner seriously interested in how those they serve are likely to set about knowing."-- ISIS. (shrink)

Although the importance, both historically and systematically, of the seventeenth century distinction between primary and secondary qualities is commonly recognised, there is no consensus on its exact nature. Apparently, one of the main difficulties in its interpretation is to tell the constitutive from the argumentative elements. In this paper, we focus on the primary-secondary quality distinctions drawn by Boyle and Locke. We criticise, more specifically, MacIntosh’s analysis of them. On the one hand, MacIntosh attributes too many different primary-secondary quality distinctions (...) to Boyle and Locke. On the other hand, he forbears to attribute a particular primary-secondary quality distinction to them, which, at least in the case of Boyle, differs genuinely from his main distinction between the mechanical affections of matter and all of matter’s other qualities. (shrink)

In part because "imagination" is a slippery notion, its exact role in the production of scientific knowledge remains unclear. There is, however, one often explicit and deliberate use of imagination by scientists that can be (and has been) studied intensively by epistemologists and historians of science: thought experiments. The main goal of this article is to document the varieties of thought experimentation, not so much in terms of the different sciences in which they occur but rather in terms of the (...) different functions they fulfil. I argue that thought experimentation (and hence imagination) plays a role not only in theory choice but in singular causal analysis and scientific discovery as well. I pinpoint, moreover, some of the rules governing the use of thought experiments in theory choice and in singular causal analysis, that is, some of the criteria they should meet in order to fulfil those functions successfully. (shrink)

Historische en systematische artikelen van Nederlandstalige filosofen over diverse aspecten van scepticisme, toen en nu, in filosofie, religie en wetenschap.

In some of the papers in which she develops and defends the mental modelview of thought experiments in physics, Nersessian expresses the belief that her account has implications for thought experiments in other domains as well. In this paper, I argue, firstly, that counterfactual reasoning has a legitimate place in historical inquiry, and secondly, that the mental model view can account for such "alternative histories". I proceed as follows. Firstly, I review the main accounts of thought experiments in physics and (...) point at some explanatory advantages of the mental model view. Subsequently, I argue that historians cannot dispense with counterfactual reasoning altogether and qualify a number of principled objections against the explicit use of alternative histories for theoretical purposes. Finally, I show that the mental model view can account for such thought experiments in history. (shrink)

Some scholars suspect that thought experiments have something in common with jokes. Moreover, Thomas Kuhn has suggested that what happens to someone who thinks through a thought experiment “is very similar to what happens to a man, like Lavoisier, who must assimilate the result of a new unexpected experimental discovery” (1964: 321). In this paper, I pinpoint the presumed commonalities. I identify, more specifically, what cognitive linguists call “incongruity-resolution” as the problem-solving process not only involved in humor comprehension, but in (...) scientific discovery and thought experimentation as well. (shrink)

Amsterdam University Press is a leading publisher of academic books, journals and textbooks in the Humanities and Social Sciences. Our aim is to make current research available to scholars, students, innovators, and the general public. AUP stands for scholarly excellence, global presence, and engagement with the international academic community.

Although Thomas More is an exemplary figure of both personal and moral integrity, his Utopia is not straightforwardly ‘integer’ in another meaning of the term, i.e., it does not unequivocally describe a ‘whole, intact or pure’ conception of the ideal society. Rather, Utopia is patently ambiguous and challenges the reader to disambiguate the narrative and to make up his own mind on how to construct the ideal society. In this paper, I analyze utopias and dystopias in general as evaluative thought (...) experiments that appeal to our imagination and deploy possible worlds. Subsequently, I argue that More’s Utopia is a successful evaluative thought experiment that actually underscores More’s integrity, because by means of its exacerbated ambiguity, it both triggers and properly respects the deliberation and evaluation of the reader in his capacity as thought experimenter. (shrink)

For almost fifty years, David Armstrong has made major contributions in analytic philosophy. The aim of this volume is to collect papers that situate, discuss and critically assess Armstrong’s contributions. The book is organized in three parts. In Section I: Analytical Metaphysics and Its Methodology, certain basic principles of analytic metaphysics advocated by Armstrong (such as truthmaker maximalism and the Doctrine of Ontological Free Lunch) and their consequences are critically examined. The articles of Section II: Laws of Nature, Dispositions, and (...) Modality, study the constraints Armstrong’s naturalism sets to his ontology of modality, laws and dispositions. Finally, the articles of Section III: Mind and Epistemology, study and critically evaluate Armstrong’s contributions in epistemology, the philosophy of perception and color. The collection is meant for all philosophers and scholars interested in these central topics of analytic philosophy. (shrink)

In his 1998 book Heterocosmica: Fiction and Possible Worlds, Lubomír Doležel put forth a theory of narrative fiction based on the interdisciplinary framework of possible worlds. In Possible Worlds of Fiction and History: The Postmodern Stage, Doležel takes his earlier theory further and applies it to historiography as well, with the specific aim of showing how the study of history might be defended against the postmodern challenge via the use of possible worlds semantics. Doležel's book is essentially an argument against (...) the postmodern views expressed by Roland Barthes and Hayden White, who have claimed that fundamentally, there is no difference between fictional and historical narratives. According to Doležel, this difference can be saved if the focus of attention is shifted from the textual features of these narratives to the fictional or historical worlds that the narratives project.Doležel's comparison of fictional and historical worlds to each other is quite illuminating and thorough. However, the question remains whether the application of PW semantics does anything besides offering a detailed analysis of the structure of the different types of narrative worlds. After all, one should not overlook the perhaps more practical way of differentiating between historical and fictional narratives through their institutional status. Furthermore, we argue that by focusing on the properties of the end products, that is, the resulting narratives, Doležel concedes too much to postmodernists. A stronger way to give postmodernists a taste of their own medicine would be to argue that the rules that historians follow in the process of generating, constructing, and evaluating weighed causal explanations are fundamentally different from whatever rules govern the generation and construction of fiction. (shrink)

In this paper we first develop a logic independent account of relevant implication. We propose a stipulative denition of what it means for a multiset of premises to relevantly L-imply a multiset of conclusions, where L is a Tarskian consequence relation: the premises relevantly imply the conclusions iff there is an abstraction of the pair such that the abstracted premises L-imply the abstracted conclusions and none of the abstracted premises or the abstracted conclusions can be omitted while still maintaining valid (...) L-consequence. Subsequently we apply this denition to the classical logic consequence relation to obtain NTR-consequence, i.e. the relevant CL-consequence relation in our sense, and develop a sequent calculus that is sound and complete with regard to relevant CL-consequence. We present a sound and complete sequent calculus for NTR. In a next step we add rules for an object language relevant implication to the sequent calculus. The object language implication reflects exactly the NTR-consequence relation. One can see the resulting logic NTR-> as a relevant logic in the traditional sense of the word. By means of a translation to the relevant logic R, we show that the presented logic NTR is very close to relevance logics in the Anderson-Belnap-Dunn-Routley-Meyer tradition. However, unlike usual relevant logics, NTR is decidable for the full language, Disjunctive Syllogism and Adjunction are valid, and neither Modus Ponens nor the Cut rule are admissible. (shrink)

L’utilitarisme de Bentham transforme profondément la doctrine antérieure de la liberté de parole en la mettant au service de la recherche de la vérité et en réfléchissant à la portée du contrôle exercé par le gouvernement. Il préserve la distinction entre les affirmations portant sur des opinions et celles portant sur des faits et accorde aux premières une moindre protection. Comme l’avait fait son père James Mill, John Stuart Mill conserve cette distinction dans ses écrits de jeunesse mais ces analyses (...) souffrent de faiblesses logiques et de naïveté politique. Dans De la liberté, John Stuart Mill cherche à dépasser ces difficultés et propose une nouvelle défense de la liberté d’expression en tant que liberté de délibération. Contrairement à la plupart des interprétations, cet article démontre que cette nouvelle approche ne remet pas en cause la distinction fondamentale entre l’expression des opinions (qui sont protégées de façon absolue) et les affirmations portant sur des faits, qui ne sont protégées que de façon contingente, ce qui laisse ouverte la possibilité de restreindre l’expression d’affirmations fausses portant sur des faits. (shrink)

Introducing and implementing corporate sustainability poses many challenges to business organizations. In this longitudinal, inductive study, we focus on how such challenges are handled in a Dutch bank that is developing its sustainability policies. We examine why there is such a high degree of tension and conflict within the organization and identify how the development of these policies is affected by the interplay between subcultures and institutional logics. We show how different subcultures affect the enactment of logics by infusing the (...) rational and mindful behavior coming from logics with (sub)cultural values, beliefs, and assumptions. In turn, conflicting logics amplify subcultural characteristics between groups by shaping different behavior and practices. Together, this leads to a magnification of subcultural differences while, at the same time, logics are increasingly being perceived as incompatible. (shrink)

This introduction to “Anthropological Philosophy: Symposium on an Unanticipated Conceptual Practice” comprises a brief history of attitudes among anthropologists toward the philosophical field of ontology, and attitudes among professional philosophers toward the kinds of alien and marginal thinking with which anthropology is concerned. After the narrative reaches what has been called the “ontological turn” in anthropology, which is generally assumed to represent the current moment in relations between the disciplines, the author discloses the recent emergence of an unexpected cultural practice: (...) a hybrid of anthropology and philosophy that takes metaphysics, as distinct from ontology, as both its object and its method. The distinction between metaphysics and ontology is crucial to this new “intellectual space” because, while ontology is an unconscious possession of any people, metaphysics is a demanding speculative discipline whose becoming an object of anthropology suggests that indigenous peoples consciously deal with questions about what is real and what is not in ways so impressive and sophisticated that they can be compared with the efforts of credentialed philosophers. In this emergent conceptual practice, moreover, the work of academic philosophers is open to elaboration and correction in response to the findings of tribal and Western marginal thinkers. Among the developers of anthropological philosophy are said to be the Brazilian anthropologist Eduardo Viveiros de Castro, the French philosopher Patrice Maniglier, and the other contributors to this symposium, whose articles the author goes on, in this context, to describe and assess. (shrink)