A Dictionary of Tocharian B: Second Edition, Revised and Greatly Enlarged. 2 vols. By Douglas Q. Adams. Leiden Studies in Indo-European, vol. 10. Amsterdam: Rodopi, 2013. Pp. xvi + v + 964. $294.

Religious beliefs, including those about an afterlife and omniscient spiritual beings, vary across cultures. We theorize that such variations may be predictably linked to ecological variations, just as differences in mating strategies covary with resource distribution. Perhaps beliefs in a soul or afterlife are more common when resources are unpredictable, and life is brutal and short.

Zeno's paradoxes of motion are considered as challenges to the practice of describing motion in terms of continuous functions. A brief description of some work of adolf gruenbaum toward the resolution of these paradoxes is given. A new form of zeno's dichotomy paradox is described, And it is claimed that the paradox, In this form, Is not amenable to the explanations of gruenbaum. This is demonstrated by giving the new form of the paradox a second, More mathematical description. In a (...) short summary it is claimed that the challenges of zeno's paradoxes are still unanswered. (shrink)

This paper argues that many of our most important theories of retributivism are unwittingly committed to the radical thesis that prepunishment—punishment before an offense—is morally permissible. From the perspective of diachronic justice on which these theories crucially depend, the timing of retribution is, ceteris paribus, irrelevant. But retributivism’s counterintuitive support does not stop there: there are conditions under which pre-offense apprehension and punishment guarantees a higher probability of justice being done. Under these conditions, the popular retributive theories I have in (...) mind do not just permit, but require, prepunishment. (shrink)

Herbert Morris argues in his influential retributivist paper, "Persons and Punishment," that criminals deserve punishment because their actions represent an unfair distribution of benefits and burdens in society. The proper distribution of benefits and burdens is important, in part, to restore law abiding citizens’ confidence that others will follow the law. In this paper I show that Morris's argument for why criminals deserve punishment morally requires us to set up an institution of rehabilitation in addition to the institution of punishment. (...) Such an institution is morally required because neither pure punishment systems nor punishment systems that incorporate quasi-rehabilitative aspects have ever worked to uphold the necessary confidence that Morris tells us law abiding citizens must have in order to protect the social order. Moreover, we cannot abandon Morris's appeal to the duty to maintain social order without also abandoning a plausibly Morrisian framework. (shrink)

BackgroundIn the Canadian Alliance for Healthy Hearts and Minds (CAHHM) cohort, participants underwent magnetic resonance imaging (MRI) of the brain, heart, and abdomen, that generated incidental findings (IFs). The approach to managing these unexpected results remain a complex issue. Our objectives were to describe the CAHHM policy for the management of IFs, to understand the impact of disclosing IFs to healthy research participants, and to reflect on the ethical obligations of researchers in future MRI studies.MethodsBetween 2013 and 2019, 8252 participants (...) (mean age 58 ± 9 years, 54% women) were recruited with a follow-up questionnaire administered to 909 participants (40% response rate) at 1-year. The CAHHM policy followed a restricted approach, whereby routine feedback on IFs was not provided. Only IFs of severe structural abnormalities were reported.ResultsSevere structural abnormalities occurred in 8.3% (95% confidence interval 7.7–8.9%) of participants, with the highest proportions found in the brain (4.2%) and abdomen (3.1%). The majority of participants (97%) informed of an IF reported no change in quality of life, with 3% of participants reporting that the knowledge of an IF negatively impacted their quality of life. Furthermore, 50% reported increased stress in learning about an IF, and in 95%, the discovery of an IF did not adversely impact his/her life insurance policy. Most participants (90%) would enrol in the study again and perceived the MRI scan to be beneficial, regardless of whether they were informed of IFs. While the implications of a restricted approach to IF management was perceived to be mostly positive, a degree of diagnostic misconception was present amongst participants, indicating the importance of a more thorough consent process to support participant autonomy.ConclusionThe management of IFs from research MRI scans remain a challenging issue, as participants may experience stress and a reduced quality of life when IFs are disclosed. The restricted approach to IF management in CAHHM demonstrated a fair fulfillment of the overarching ethical principles of respect for autonomy, concern for wellbeing, and justice. The approach outlined in the CAHHM policy may serve as a framework for future research studies.Clinical trial registrationhttps://clinicaltrials.gov/ct2/show/nct02220582. (shrink)

Though antiretroviral therapy is the standard of care for people living with HIV, its treatment limitations, burdens, stigma and costs lead to continued interest in HIV cure research. Early-phase cure trials, particularly those that include analytic treatment interruption, involve uncertain and potentially high risk, with minimal chance of clinical benefit. Some question whether such trials should be offered, given the risk/benefit imbalance, and whether those who choose to participate are acting rationally. We address these questions through a longitudinal decision-making study (...) nested in a Thai acute HIV research cohort. In-depth interviews revealed central themes about decisions to join. Participants felt they possessed an important identity as members of the acute cohort, viewing their bodies as uniquely suited to both testing and potentially benefiting from HIV cure approaches. While acknowledging risks of ATI, most perceived they were given an opportunity to interrupt treatment, to test their own bodies and increase normalcy in a safe, highly monitored circumstance. They were motivated by potential benefits to themselves, the investigators and larger acute cohort, and others with HIV. They believed their own trial experiences and being able to give back to the community were sufficient to offset participation risks. These decisions were driven by the specific circumstances experienced by our participants. Judging risk/benefit ratios without appreciating these lived experiences can lead to false determinations of irrational decision- making. While this does not minimise vital oversight considerations about risk reduction and protection from harm, it argues for inclusion of a more participant-centered approach. (shrink)

We provide a retrospective of 25 years of the International Conference on AI and Law, which was first held in 1987. Fifty papers have been selected from the thirteen conferences and each of them is described in a short subsection individually written by one of the 24 authors. These subsections attempt to place the paper discussed in the context of the development of AI and Law, while often offering some personal reactions and reflections. As a whole, the subsections build into (...) a history of the last quarter century of the field, and provide some insights into where it has come from, where it is now, and where it might go. (shrink)

One of the challenging problems in large scale cyber-argumentation platforms is that users often engage and focus only on a few issues and leave other issues under-discussed and under-acknowledged. This kind of non-uniform participation obstructs the argumentation analysis models to retrieve collective intelligence from the underlying discussion. To resolve this problem, we developed an innovative opinion prediction model for a multi-issue cyber-argumentation environment. Our model predicts users’ opinions on the non-participated issues from similar users’ opinions on related issues using intelligent (...) argumentation techniques and a collaborative filtering method. Based on our detailed experimental results on an empirical dataset collected using our cyber-argumentation platform, our model is 21.7% more accurate, handles data sparsity better than other popular opinion prediction methods. Our model can also predict opinions on multiple issues simultaneously with reasonable accuracy. Contrary to existing opinion prediction models, which only predict whether a user agrees on an issue, our model predicts how much a user agrees on the issue. To our knowledge, this is the first research to attempt multi-issue opinion prediction with the partial agreement in the cyber-argumentation platform. With additional data on non-participated issues, our opinion prediction model can help the collective intelligence analysis models to analyze social phenomena more effectively and accurately in the cyber argumentation platform. (shrink)

Vaccine refusal forces us to confront tensions between many values, including scientific expertise, parental rights, children’s best interests, social responsibility, public trust, and community health. Recent outbreaks of vaccine-preventable and emerging infectious diseases have amplified these issues. The prospect of a coronavirus disease 2019 vaccine signals even more friction on the horizon. In this contentious sociopolitical landscape, it is therefore more important than ever for clinicians to identify ethically justified responses to vaccine refusal.

Pancreatitis is a complex, progressively destructive inflammatory disorder. Alcohol was long thought to be the primary causative agent, but genetic contributions have been of interest since the discovery that rare PRSS1, CFTR and SPINK1 variants were associated with pancreatitis risk. We now report two associations at genome-wide significance identified and replicated at PRSS1-PRSS2 and X-linked CLDN2 through a two-stage genome-wide study. The PRSS1 variant likely affects disease susceptibility by altering expression of the primary trypsinogen gene. The CLDN2 risk allele is (...) associated with atypical localization of claudin-2 in pancreatic acinar cells. The homozygous CLDN2 genotype confers the greatest risk, and its alleles interact with alcohol consumption to amplify risk. These results could partially explain the high frequency of alcohol-related pancreatitis in men. © 2012 Nature America, Inc. All rights reserved. (shrink)

Precision testing of the quantum electrodynamics (QED) and the standard model provides some of the most secure knowledge in the history of physics. These tests can also be used to constrain and search for new physics going beyond the standard model. We examine the evidential structure of relationships between theoretical predictions from QED, precision measurements of these phenomena, and the indirect determination of the fine structure constant. We argue that "pure QED" is no longer sufficient to predict the electron's anomalous (...) magnetic moment, and that standard model effects are needed. The details relevant to low-energy QED are robust against future theory change. (shrink)

Cutting and parsing the corpus of a great author’s work is properly a delicate and exacting task, particularly when executed by numerous authors within the limits of a three-hundred-page academic b...

This article develops an analogy proposed by Stachel between general relativity (GR) and quantum mechanics (QM) as regards permutation invariance. Our main idea is to overcome Pooley's criticism of the analogy by appeal to paraparticles. In GR, the equations are (the solution space is) invariant under diffeomorphisms permuting spacetime points. Similarly, in QM the equations are invariant under particle permutations. Stachel argued that this feature—a theory's ‘not caring which point, or particle, is which’—supported a structuralist ontology. Pooley criticizes this analogy: (...) in QM the (anti-)symmetrization of fermions and bosons implies that each individual state (solution) is fixed by each permutation, while in GR a diffeomorphism yields in general a distinct, albeit isomorphic, solution. We define various versions of structuralism, and go on to formulate Stachel's and Pooley's positions, admittedly in our own terms. We then reply to Pooley. Though he is right about fermions and bosons, QM equally allows more general types of particle symmetry, in which states (vectors, rays, or density operators) are not fixed by all permutations (called ‘paraparticle states’). Thus Stachel's analogy is revived. (shrink)

One of Jerry Fodor’s many seminal contributions to philosophy of mind was his inner sentence theory of belief and desire. To believe that p is to have a subpersonal inner sentence in one’s “belief-box” that means that p, and to desire that q is to have a subpersonal inner sentence in one’s “desire-box” that means that q. I will distinguish between two accounts of box-inclusion that exhaust the options: liberal and restrictive. I will show that both accounts have the mistaken (...) implication that in certain cases there can be radical but “secret” changes in a subject’s beliefs and desires. I will suggest that the correct moral to draw is that we should instead accept what Eric Schwitzgebel has called a “surface-level” theory of belief and desire. (shrink)

In contrast to classical natural law theory and traditional individualist liberalism, James Luther Adams develops a version of natural law doctrine grounded in liberal religion. In its ontological dimension, his natural law doctrine is derived from a communal understanding of the character of reality. In its institutional dimension, his natural law doctrine promotes a kind of democracy in which freedom of association is central. From this perspective, law is a practice intended to empower persons through their several associations in (...) the constant formation and transformation of community under the direction of divine power. (shrink)

David Hume, Adam Smith, Jeremy Bentham and John Stuart Mill are often viewed as contributors to or participants in a common tradition of thought roughly characterized as ‘the liberal tradition’ or the tradition of ‘bourgeois ideology’. This view, however useful it may be for polemical or proselytizing purposes, is in some important respects historiographically unsound. This is not to deny the importance of asking what twentieth-century liberals or conservatives might find in the works of, say, David Hume to support their (...) respective ideological persuasions. It is only to insist that attempts to use selected arguments, or parts of arguments, from great eighteenth-century thinkers to shore up twentieth-century programmatic political positions must be categorically distinguished from attempts to understand what Hume, Smith, Bentham or Mill actually meant, or could imaginably have meant, to say. (shrink)

The claim of this paper is that the everyday functions of knowledge make most sense if we see knowledge as contrastive. That is, we can best understand how the concept does what it does by thinking in terms of a relation “a knows that p rather than q.” There is always a contrast with an alternative. Contrastive interpretations of knowledge, and objections to them, have become fairly common in recent philosophy. The version defended here is fairly mild in that there (...) is no suggestion that we cannot think in terms of a simpler not explicitly contrastive relation “a knows that p.” Some, for instance Schaffer (2005) and Karjalainen and Morton (2003), have hinted that this stronger possibility may be right. But all that I am arguing now is that facts that are easily expressed in contrastive terms are vital to understanding why we need the concept of knowledge. In a piece that is in some ways a companion to this one ("Contrastivism" in Duncan Pritchard and Sven Bernecker, eds. The Routledge Companion to Epistemology. Routledge 2010, 513-522), I give a general survey of theories of contrastive knowledge and the differences between them. (shrink)

The past ten years have seen multiple attempts to estimate the relation between the global personality trait extraversion and compatibilist free will judgments. Here, we contribute to that line of research by conducting a meta-analysis of 17 published and eight unpublished studies (N = 2,811) estimating that relation. Overall, the mean effect size was modest but remarkably robust across materials, locations, and labs (z =.19, 95% CI.15-.24, p <.001). No significant publication bias was detected in the studies (t (23) = (...) 1.88, p =.07). While there was no significant heterogeneity in the studies (Q (24) = 34.42, p =.08, I2 = 26.05), a moderator analysis suggested that the effect is strongest in cases that contain highly affective actions (e.g., murder) (z =.22, 95% CI.17-.28, p <.001) and weakest in cases that contain actions with low affect (e.g., asking whether free will is compatible with determinism) (z =.09, 95% CI -.05-.23, p =.22). The meta-analysis provides additional evidence that extraversion is related to compatibilist free will judgments and helps to identify opportunities to discover boundary conditions and more proximal causal mechanisms for the relation. The results of the meta-analysis also have implications for informed decision making. (shrink)

This article aims to contextualize a short Qurʾānic passage – Q 30:2‒5 – with reference to Jewish and Christian materials that have not hitherto been deployed for this purpose. The article builds on the findings of recent scholarship, which reads this passage eschatologically rather than historically, and argues that there are, in fact, two texts that require contextualization: 1) The Qurʾānic verses themselves (which refer only to the fate of “the Romans”); and 2) The early exegetical traditions on these verses (...) (which often add “the Persians” to the eschatological drama). Furthermore, it is argued that the Biblical book of Daniel, and its interpretation in late antiquity, contributed both to the verses themselves and to their exegesis. (shrink)

Anthony Ashley Cooper, the Third Earl of Shaftesbury, was the grandson of the First Earl of Shaftesbury. The First Earl, along with John Locke, was a leader and founder of the Whig movement in Britain. Locke was the First Earl's secretary and also the tutor of the Third Earl. Both the First and Third Earls were members of parliament and supporters of Whig causes. Although both the First and Third Earls were involved in politics, the Third Earl is better known (...) for intellectual pursuits. Indeed, the Third Earl is second only to Locke in terms of influence during the eighteenth century. Yet if one takes into account effects upon literature, the arts, and manners, as well as upon philosophical trends and theories, Shaftesbury might be even more influential. Even if we restrict ourselves to philosophy, Shaftesbury's ideas were admired by thinkers as different as Leibniz and Montesquieu—something which could obviously not be said about Locke. Within ethics, Shaftesbury influenced Francis Hutcheson, David Hume, Samuel Butler, and Adam Smith and is credited with founding the “moral sense” school of thought. (shrink)

This article seeks to contribute to our understanding of a short Qurʾānic passage, Q 85:4‒10, which concerns the fate of the enigmatic Aṣḥāb al-Ukhdūd. It is argued that the ‘eschatological’ and ‘historical’ readings of this passage, which have generally been taken to be mutually exclusive options for its interpretation, are both indispensable for a full contextualization of the verses in question. Furthermore, regarding the historical reading of the passage, it is argued that the verses refer to the events recorded in (...) Daniel 3, rather than to the Martyrs of Najrān episode that most exegetes (and many modern scholars) opt for. Finally, a new etymology for the word Ukhdūd is proposed. (shrink)

The theory of competition has held a central place in economic analysis since Adam Smith. This book, written by one of the most distinguished of contemporary economic theorists, reports on a major research program to provide strategic foundations for the theory of perfect competition. Beginning with a concise survey of how the theory of competition has evolved, Gale makes extensive and rigorous use of dynamic matching and bargaining models to provide a more complete description of how a competitive equlibrium is (...) achieved. Whereas economists have made use of a macroscopic description of markets in which certain behavioral characteristics, such as price-taking behavior, are taken for granted, Gale uses game theory to re-evaluate this assumption, beginning with individual agents and modelling their strategic interaction. A strategic foundation for competitive equilibrium shows how such interaction leads to competitive, price-taking behavior. Essential reading for graduate courses in game theory and general equilibrium. (shrink)

We give a general description of a class of contrastive constructions, intended to capture what is common to contrastive knowledge, belief, hope, fear, understanding and other cases where one expresses a propositional attitude in terms of “rather than”. The crucial element is the agent's incapacity to distinguish some possibilities from others. Contrastivity requires a course-graining of the set of possible worlds. As a result, contrastivity will usually cut across logical consequence, so that an agent can have an attitude to p (...) rather than q but not to r rather than q , where r is a logical consequence of p . We relate these ideas to some general issues about thought, such as the question of whether all possibilities that can be distinguished in emotion can be distinguished in belief. (shrink)

A minimal extension of a Π01 class P is a Π01 class Q such that P ⊂ Q, Q – P is infinite, and for any Π01 class R, if P ⊂ R ⊂ Q, then either R – P is finite or Q – R is finite; Q is a nontrivial minimal extension of P if in addition P and Q′ have the same Cantor-Bendixson derivative. We show that for any class P which has a single limit point A, (...) and that point of degree ≤ 0, P admits a nontrivial minimal extension. We also show that as long as P is infinite, then P does not admit any decidable nontrivial minimal extension Q. (shrink)

Thomas Nadelhoffer claims that a morally praiseworthy agent cannot knowingly produce a morally positive side effect. I claim that the argument Nadelhoffer uses to establish this claim has two false premises. The two false premises are: If something is a side effect, then it is not desired or intended; and If agent S is morally praiseworthy and knows that her performing p will produce a morally positive q, then q forms part of S's reason for p-ing. I offer a counterexample (...) that shows the falsity of and . 2012 APA, all rights reserved). (shrink)

Closure is the epistemological thesis that if S knows that P and knows that P implies Q, then if S infers that Q, S knows that Q. Fred Dretske acknowledges that closure is plausible but contends that it should be rejected because it conflicts with the plausible thesis: Conclusive reasons (CR): S knows that P only if S believes P on the basis of conclusive reasons, i.e., reasons S wouldn‘t have if it weren‘t the case that P. Dretske develops an (...) analysis of knowing that centers on CR, and argues that the requirement undermines skepticism by implying the falsity of closure. We develop a Dretske-style analysis of knowing that incorporates CR, and we argue that this analysis not only accords with closure, but also implies it. In addition, we argue that the analysis accounts for the prima facie plausibility of closure-invoking skeptical arguments, and nonetheless implies that they are fallacious. If our arguments turn out to be sound, the acceptability of Dretske‘s analysis of knowing will be significantly enhanced by the fact that, despite implying closure, it undermines closure-based skepticism. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Aquinas and Dōgen on Entrance into the Religious LifeDouglas K. MikkelsonComparative studies of Christianity and Buddhism have the potential to draw on a wide array of dialogic partners from their respective histories. Two promising candidates are Thomas Aquinas (1225–1274) and Dōgen (1200–1253). Aquinas was the angelic doctor whose theological thinking became normative for Roman Catholicism; Dōgen was the prominent Zen master whose influence on the intellectual development of Zen (...) Buddhism is unsurpassed. As it happens, both men "entered into the religious life," and within their respective collected works we see considerable attention to the topic. If we seek to explore what they had to say on the subject, we might benefit by identifying some texts from both thinkers that could serve as focal points for a comparative analysis. Of the massive accumulated writings of both men, the largest are Aquinas's Summa Theologiae and Dōgen's Shōbōgenzō. So it seems logical to start our search by turning our attention to these monumental works.Let us begin with the Summa Theologiae. In the secunda secundae Aquinas addresses a total of 189 topics presented in a question-and-answer format. The first 170 topics concern "themes related to all stations of life"; questions 171–189 explore "details related to particular callings" (2a2ae, Prologus). Question 189, hereinafter identified as 2a2ae q. 189, is specifically devoted to the topic of "entering the religious life" (de ingressu religionis).1When we turn to the Shōbōgenzō, we find a work titled Shukke Kudoku. "Kudoku" means "merit"; "shukke," commonly translated as "leaving home," denotes a person who has renounced home and family in order to enter monastic life. Thus "Shukke Kudoku" can be rendered in English as "The Merit of Entering the Religious Life."2Given that these texts are relatively accessible and substantive presentations of comparable length on issues pertaining to the religious life, they seem to be good focal points for this discussion. At the same time, both thinkers addressed the subject in other venues also, and we can briefly refer to this material as well. But in this article I will primarily concentrate on how a comparative analysis of these two texts illuminates the subject. Defining the discussion in this fashion has the advantage of presenting Aquinas's and Dōgen's views in a particular time and place, leaving aside the more complex issue of how their views may have changed over time. [End Page 109]Let us begin with Aquinas. Aquinas begins 2a2ae q. 189 by outlining ten points of inquiry to be pursued, in effect dividing the question into ten subquestions. The first on the list is "whether those alone should enter religious life who are practiced in keeping the commandments." The commandments he means, of course, are the precepts of the decalogue, the Ten Commandments of Exodus 20:17 and Deut. 5:6–21.Aquinas's standard modus operandi was to first entertain arguments leading to aconclusion opposing his own. In this question he outlines five lines of argument, and in each instance the arguments lead to the assertion that one should not practice the counsels "until one is practiced in keeping the commandments" (nisi prius sit exercitatus in praeceptis); by "counsels" Aquinas means the observance of poverty, chastity, and obedience that are undertaken by those who enter the religious life. As he had explained previously, "The difference between a counsel and a precept lies in this, that a precept implies necessity, while a counsel is left to the choice of the one to whom it is given" (1a2ae q. 108.4).3 Precepts such as the commandments, in other words, enjoin an obligation; counsels are optional.We will discover Aquinas's own answer soon, but we should first note how Aquinas begins his discussion of entrance into the religious life. He begins by posing a question about whether or not one practiced in keeping the commandments should enter the religious life. In the course of answering his own question, he essentially reframes it, seeking to explore whether or not one should practice the counsels before one has become adept at keeping the commandments. For Aquinas, both formulations... (shrink)

THE CENTRALITY OF "SYMPATHY" to Adam Smith's Theory of Moral Sentiments points to the centrality of love in the book. While Smith delineates a somewhat unusual, technical sense of "sympathy", his actual use of the term frequently slips into its more ordinary sense of "compassion" or affectionate fellow feeling. This no doubt intentional equivocation on Smith's part helps suffuse the book with these themes, to the point that, without much exaggeration, one could say that the Theory of Moral Sentiments is (...) generally about love: our need for love and sympathy, love as friendship, self-love, the love of praise and praiseworthiness, the love of beauty. Even in the Wealth of Nations, our loves are thought to be very important in explaining our behavior. Smith is unusual among modern moral philosophers in according so central a place to love in this broad sense, although of course Christianity made love a central theme in reflection on ethical life, and philosophers such as Hutcheson made benevolence a key virtue in their ethical systems. However, it is not our purpose to examine Smith's critique of Hutcheson or indeed of any of his predecessors. Rather we aim in this paper to reflect on his treatment of this topic. We shall do so in part by means of comparisons with Aristotle and Plato, first with respect to friendship and then with respect to love generally. Smith's writing is replete with classical references, raising the issue of the degree to which his thought is "ancient" or "modern." Friendship is arguably the pinnacle of social relations for the ancients, and thus it provides us with a useful device for determining the degree to which Smith's thought embodies classical moral and philosophical principles. The subtlety of Smith's interweaving of traditions will become visible as we reflect not just on the ways Smith's thought exhibits classical conceptions of friendship and love, but also on the ways he departs from them. For in at least one important respect, love is a closed book from Smith's standpoint, and thus, as it turns out, also at odds with classical friendship. (shrink)