BackgroundIn the Canadian Alliance for Healthy Hearts and Minds (CAHHM) cohort, participants underwent magnetic resonance imaging (MRI) of the brain, heart, and abdomen, that generated incidental findings (IFs). The approach to managing these unexpected results remain a complex issue. Our objectives were to describe the CAHHM policy for the management of IFs, to understand the impact of disclosing IFs to healthy research participants, and to reflect on the ethical obligations of researchers in future MRI studies.MethodsBetween 2013 and 2019, 8252 participants (...) (mean age 58 ± 9 years, 54% women) were recruited with a follow-up questionnaire administered to 909 participants (40% response rate) at 1-year. The CAHHM policy followed a restricted approach, whereby routine feedback on IFs was not provided. Only IFs of severe structural abnormalities were reported.ResultsSevere structural abnormalities occurred in 8.3% (95% confidence interval 7.7–8.9%) of participants, with the highest proportions found in the brain (4.2%) and abdomen (3.1%). The majority of participants (97%) informed of an IF reported no change in quality of life, with 3% of participants reporting that the knowledge of an IF negatively impacted their quality of life. Furthermore, 50% reported increased stress in learning about an IF, and in 95%, the discovery of an IF did not adversely impact his/her life insurance policy. Most participants (90%) would enrol in the study again and perceived the MRI scan to be beneficial, regardless of whether they were informed of IFs. While the implications of a restricted approach to IF management was perceived to be mostly positive, a degree of diagnostic misconception was present amongst participants, indicating the importance of a more thorough consent process to support participant autonomy.ConclusionThe management of IFs from research MRI scans remain a challenging issue, as participants may experience stress and a reduced quality of life when IFs are disclosed. The restricted approach to IF management in CAHHM demonstrated a fair fulfillment of the overarching ethical principles of respect for autonomy, concern for wellbeing, and justice. The approach outlined in the CAHHM policy may serve as a framework for future research studies.Clinical trial registrationhttps://clinicaltrials.gov/ct2/show/nct02220582. (shrink)

The Vygotsky Anthology brings together, for the first time, a selection of extracts from the best translations available of Vygotsky's writings, spanning the entire arc of his career. Vygotsky was arguably one of the greatest educational psychologists of the 20th century. Grounded in his experience as a teacher, an expert in special education, a research psychologist and an outstanding theorist, the editors of this unique anthology chart his enormous influence on professionals working in education and child development around the world. (...) The extracts are introduced by the editors' commentaries, helpfully setting them in the context of Vygotsky's life and work, providing a collection of work that adequately represents his writing, and conveying some of the great pleasures of reading him. In the passages selected here, his voice is clearly heard, the intellectual brilliance of his insights is reflected, his line of argument is clear, and his humour and humanity are evident. With its inclusion of recent translations of essential texts, this anthology will help students to understand the full diversity of Vygotsky's influence on today's classrooms. Seen as a companion volume to Myra Barr's previous work Vygotsky the Teacher (Routledge, 2022), the value of this text to teachers, educational psychologists, and other practitioners working in the field of education and child development, will be significant and lasting. It is a key reference book for new generations of Vygotsky students. (shrink)

On bioethics related to humanism; papers of a seminar.

In computer science, an algorithm is an unambiguous specification of how to solve a class of problems. Algorithms can perform calculation, data processing and automated reasoning tasks. As an effective method, an algorithm can be expressed within a finite amount of space and time and in a well-defined formal language for calculating a function. Starting from an initial state and initial input (perhaps empty), the instructions describe a computation that, when executed, proceeds through a finite number of well-defined successive states, (...) eventually producing "output" and terminating at a final ending state. The transition from one state to the next is not necessarily deterministic; some algorithms, known as randomized algorithms, incorporate random input. This book introduces a set of concepts in solving problems computationally such as Growth of Functions; Backtracking; Divide and Conquer; Greedy Algorithms; Dynamic Programming; Elementary Graph Algorithms; Minimal Spanning Tree; Single-Source Shortest Paths; All Pairs Shortest Paths; Flow Networks; Polynomial Multiplication, to ways of solving NP-Complete Problems, supported with comprehensive, and detailed problems and solutions, making it an ideal resource to those studying computer science, computer engineering and information technology. (shrink)

The subject matter of this paper is the view that it is correct, in an absolute sense, to believe a proposition just in case the proposition is true. I take issue with arguments in support of this view put forward by Nishi Shah and David Velleman.

1. Hŏryŏng, t'ŏng piŏ yŏnghwarhan maŭm -- 2. Ajik tŭrŏnaji anŭn maŭm esŏ chigak i kanŭng han'ga -- 3. Mibal kwa kijil ŭn ŏttŏn kwan'gye in'ga -- 4. Umjiginŭn maŭm kwa koyohan maŭm -- 5. Chigak ŭi sŏnggyŏk kwa kŭ yŏnwŏn e kwanhan munje.

This volume provides a clear and accessible overview of central concepts, positions, and arguments in virtue ethics. While it focuses primarily on Aristotelian virtue ethics, it also includes discussion of alternative forms of virtue ethics and competing normative theories. The first six chapters are organized around central questions in normative ethics that are of particular concern to virtue ethicists and their critics: -/-  What is virtue ethics?  What makes a trait a virtue?  Is there a link between (...) virtue and happiness?  What is involved in being well-motivated?  What is practical wisdom?  What makes an action right? -/- The last four chapters focus on important challenges or objections to virtue ethics: -/-  Can virtue ethics be applied to particular moral problems?  Does virtue ethics ultimately rely on moral principles?  Can it withstand the situationist critique?  What are the prospects for an environmental virtue ethics? -/- With useful Summaries and Further Reading sections at the end of each chapter, the book is written for advanced undergraduates, but should also be useful to graduate students, professional philosophers, and anyone interested in normative ethics, applied ethics, moral psychology, or moral education. (shrink)

In Working Virtue: Virtue Ethics and Contemporary Moral Problems, leading figures in the fields of virtue ethics and ethics come together to present the first ...

Studie over het verschijnsel helderziendheid waarbij de verschillende in de loop der tijden ontwikkelde theorieën en verklaringen in een logisch verband behandeld worden.

To the sceptic's contention that I don't know that I have hands because I don't know that there is an external world, the Moorean replies that I know that there is an external world because I know that I have hands. Crispin Wright has argued that the Moorean move is illegitimate, and has tried to block it by limiting the applicability of the principle of the transmission of knowledge by inference—the principle that recognising the validity of an inference from known (...) premises generates knowledge of the conclusion. I argue that, in the presence of some plausible assumptions, blocking the Moorean move does not require limiting the applicability of the transmission principle. Then I argue against Jim Pryor's contention that the Moorean argument transmits evidential support from its premises to its conclusion. (shrink)

Are your students prepared? Are they ready to view the world through biblical lenses? Are they equipped to engage the world with scriptural discernment? Biblical Worldview: Creation, Fall, Redemption is a tool that helps teachers equip 11th or 12th grade students with a Christian understanding of all major academic disciplines and cultural arenas. Course goals: Define worldview and demonstrate how worldviews influence the way people think about all of life; Analyze a Biblical worldview in terms of Creation, Fall and Redemption; (...) Apply Creation, Fall and Redemption to real-life issues as well as to making positive contributions to life and culture. Biblical Worldview: Creation, Fall, Redemption Student Text was created to appeal to student interest and develop understanding. Application examples taken from history and recent events resonate with students, motivating them to apply Scripture to issues that are crucial to their spiritual growth. Apologetics is interwoven throughout the textbook, equipping students to defend the foundational teachings of the Bible against competing worldviews. At the same time, the framework of Creation, Fall, Redemption enables students to make distinctively Christian contributions to their culture. (shrink)

Weaving together state-of-the-art research, theory, and clinical insights, this book provides a new understanding of the unconscious and its centrality in human functioning. The authors review heuristics, implicit memory, implicit learning, attribution theory, implicit motivation, automaticity, affective versus cognitive salience, embodied cognition, and clinical theories of unconscious functioning. They integrate this work with cognitive neuroscience views of the mind to create an empirically supported model of the unconscious. Arguing that widely used psychotherapies--including both psychodynamic and cognitive approaches--have not kept pace (...) with current science, the book identifies promising directions for clinical practice. Subject areas/Key words: unconscious processes, human consciousness, psychoanalysis, psychoanalytic theory, implicit learning, implicit memory, implicit motivation, automaticity, cognition, subconscious, psychodynamic psychotherapy, mind, computational neuroscience, empirical research Audience: Clinical psychologists, psychiatrists, psychoanalysts, and other mental health practitioners, as well as researchers and students of clinical and personality psychology and psychopathology. (shrink)

The T&T Clark Handbook of Christian Ethics provides an ecumenical introduction to Christian ethics, its sources, methods, and applications. With contributions by theological ethicists known for their excellence in scholarship and teaching, the essays in this volume offer fresh purchase on, and an agenda for, the discipline of Christian ethics in the 21st century. The essays are organized in three sections, following an introduction that presents the four-font approach and elucidates why it is critically employed through these subsequent sections. The (...) first section explores the sources of Christian ethics, including each of the four fonts: scripture, tradition, experience, and reason. The second section examines fundamental or basic elements of Christian ethics and covers different methods, approaches, and voices in doing Christian ethics, such as natural law, virtue ethics, conscience, responsibility, narrative, worship, and engagement with other religions. The third section addresses current moral issues in politics, medicine, economics, ecology, criminal justice and other related spheres from the perspective of Christian ethics, including war, genetics, neuroethics, end-of-life decisions, marriage, family, work, sexuality, nonhuman animals, migration, aging, policing, incarceration, capital punishment, and more. (shrink)

Our human forms of embodiment, the many various ways real bodies appear in the real world, structure our experiences, memories, thoughts, and language in ways both subtle and important. On The Good Place, we have bodies in the afterlife, and they must be real enough that they can be filled with pins and butthole spiders. Researchers recognized the importance of having a body in the real world as a method of building artificial intelligence (AI). Throughout the first three seasons of (...) The Good Place, Janet herself recognizes the ways she is changing. The change is subtle early on, so it's easy to continue to see her as the Busty Alexa that Eleanor sees at first. Janet is a refreshing way to think about AI going forward. She is a model for how AI researchers ought to think about the emergence of mind, thoughts and feelings that a system previously lacked. (shrink)