Genesis: The Evolution of Biology presents a history of the past two centuries of biology, suitable for use in courses, but of interest more broadly to evolutionary biologists, geneticists, and biomedical scientists, as well as general readers interested in the history of science. The book covers the early evolutionary biologists-Lamarck, Cuvier, Darwin and Wallace through Mayr and the neodarwinian synthesis, in much the same way as other histories of evolution have done, bringing in also the social implications, the struggles with (...) our religious understanding, and the interweaving of genetics into evolutionary theory. What is novel about Sapp's account is a real integration of the cytological tradition, from Schwann, Boveri, and the other early cell biologists and embryologists, and the coverage of symbiosis, microbial evolutionary phylogenies, and the new understanding of the diversification of life coming from comparative analyses of complete microbial genomes. The book is a history of theories about evolution, genes and organisms from Lamarck and Darwin to the present day. This is the first book on the general history of evolutionary biology to include the history of research and theories about symbiosis in evolution, and first to include research on microbial evolution which were excluded from the classical neo-Darwinian synthesis. Bacterial evolution, and symbiosis in evolution are also excluded from virtually every book on the history of biology. (shrink)

Constantin Merezhkowsky is celebrated today for his theory of symbiogenesis, postulated in the early decades of the twentieth century, particularly that chloroplasts were symbiotic cyanophytes (cyanobacteria). While biologists point singularly to what they see as his heroic achievement, its neglect and subsequent rediscovery, we introduce a broader and much more complex perspective on his science, his troubled life and career. We present a view of Merezhkowsky as zoologist, anthropologist, botanist, philosopher, and novelist. We explain the genesis of his theory of (...) the origin of chloroplasts and of nucleus and cytoplasm as symbionts, as well as his depiction of the geo-chemical context of the origins and early evolution of life on earth. We also disclose his sordid social and political activities, his eugenics and racist writings, his paedophilia, and his metaphysics. Finally, we describe the context of his elaborate suicide in 1921. (shrink)

The century-old controversy over the reproduction and function of the centriole is examined to elucidate the conceptual and methodological issues that have made it so resistant to closure. The study of centrioles is situated in two distinct eras punctuated by the deployment of the electron microscope. From the late 19th century to the mid-20th century, centrioles were defined largely in functional terms- as self-reproducing 'central bodies' playing a directive role in mitosis. During this period, when their structure remained unknown, their (...) universal presence in all cells was ambiguous, and their reality was seriously debated. A conceptual switch occurred after the mid 1950s. When the centriole was made visible under the electron microscope, it was defined in terms of its characteristic cartwheel structure, but its function and manner of reproduction have remained enigmatic. The controversy over the nature of centrioles illustrates the dynamic interplay of techniques, theories, and background assumptions in the production of scientific knowledge. It also highlights the difficulties biologists face in coming to grips with problems of cell structure and intracellular morphogenesis. (shrink)

The scope and significance of lateral gene transfer (LGT) has been discussed periodically since the early twentieth century. In sketching this history here we see that the pendulum of opinion has swung from one extreme that LGT is a rare phenomenon to the other that it is fundamental to evolution. That phages are sources of bacterial evolutionary innovation has been discussed since the 1920s in association with evidence that symbiosis is a major source of evolutionary innovation. Concepts of infectious heredity (...) re-emerged with the rise of bacterial genetics after the Second World War, but LGT was generally discounted as a significant evolutionary force. LGT received increased attention in the 1960s and 1970s because of its role in antibiotic resistance outbreaks. Some speculated that the new molecular approaches to bacterial phylogenetics were ill-conceived because of LGT. With the rise of genomics in the 1990s, it became clear to phylogeneticists that LGT is the principal mode of generating evolutionary novelty in the prokaryotic world. All microbiologists agree today that the Darwinian concept of a bifurcating tree is an inadequate, if not misleading, representation of the evolutionary process in the microbial world. Phages are also reconceived not only as agents of bacterial gene exchange, but also as organisms in their own right, and fundamental in the evolution of new genes. (shrink)

Stephenson (2022) has argued that Kant’s thesis that all transcendental truths are transcendentally a priori knowable leads to omniscience of all transcendental truths. His arguments depend on luminosity principles and closure principles for transcendental knowability. We will argue that one pair of a luminosity and a closure principle should not be used, because the closure principle is too strong, while the other pair of a luminosity and a closure principle should not be used, because the luminosity principle is too strong. (...) Stephenson’s argument also depends on a factivity principle for transcendental knowability, which we will argue to be false. (shrink)

1. Die erste Hälfte des Kommentars, mit Ausnahme der Kapitel über die Weltseele.

'What is real?' has been one of the key questions of philosophy since its beginning in antiquity. But it is not just a question that philosophers ask. This Very Short Introduction discusses what reality is by looking at a variety of arguments, theories, and thought-experiments from philosophy, physics, and cognitive science.

A number of well-developed theories shed light on the question, under what circumstances our beliefs enjoy epistemic justification. Yet, comparatively little is known about epistemic defeat--when new information causes the loss of epistemic justification. This book proposes and defends a detailed account of epistemic defeaters. The main kinds of defeaters are analyzed in detail and integrated into a general framework that aims to explain how beliefs lose justification. It is argued that defeaters introduce incompatibilities into a noetic system and thereby (...) prompt a structured re-evaluation process that makes a justified reinstatement of the defeated belief impossible. The account is then applied to the topic of disagreement, where it is used in an argument for conciliationism, as well as a new explanation for higher-order defeat. Throughout the book, the notion of defeat is the center of attention, while a number of new issues are discussed at the intersections of defeat and justification. Specifically, new problems are raised for broadly internalist accounts of defeat, a fully descriptive reliabilist account of defeat is provided, and the case for normative defeat is revisited. (shrink)

The Natural Philosophy of Jan Bayer The main focus of this study is a reconstruction of the natural philosophy of the early modern Prešov's scholar Jan (Johannes) Bayer (1630–1674), with special regard to its Mosaic profile. After a critical reading of the research done on Bayer up to this point, the author concludes that Bayer’s natural-philosophical work, as such, has not yet been satisfactorily analyzed, nor has its connection to its supposedly two most important sources, Francis Bacon and Jan Amos (...) Comenius, been sufficiently explored. The study therefore concentrates on a critical analysis of Bayer’s interpretation of creation and his natural history, which are then both situated in the philosophical context of their time. The author then notes that although Bayer’s project of erecting an original and on the (especially Aristotelian) tradition independent Mosaic natural philosophy ended in failure, the thinker’s work can be assessed as a valuable attempt to synthesize Baconian and Comenian motifs while at the same time reflecting broader intellectual contexts of the period. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:The Fate of Eloquence in the Age of HumeVicki J. SappThe Fate of Eloquence in the Age of Hume, by Adam Potkay; xii & 253 pp. Ithaca: Cornell University Press, 1994, $36.95.With the memory still fresh of Jerome Christensen’s Practicing Enlightenment, I experienced no small anxiety on reading Adam Potkay’s first acknowledgment, to Prof. Christensen and his “provocative seminar” on Hume. I finished a third of The Fate (...) of Eloquence in the Age of Hume before the overt nod, when Potkay spotlights the essayist Hume’s appeal to a female readership: “Within this doux commerce, the figures of classical eloquence are entirely too priapic—too ‘swelling... monstrous and gigantic’—to be admitted” (p. 75). However, Hume’s self-castration wound is mercifully left unprobed, and the priapus doesn’t come up again until Potkay’s own prosopopoeia, “ancient eloquence’s priapic energy” (p. 158). Although he follows Christensen’s equation of polite letters with effeminacy, Potkay treats gender more materially than metaphorically. Although attending to his poststructuralist debts with such observations as “Hume, the unmoved mover, observes the spiritual implosion of one whose passions cannot, like his own, be alleviated through voyeurism” (p. 125), Potkay ultimately fulfills his promise to draw his insights from “a history of eighteenth-century reading and reception” (p. 22). In a clear prose he conveys his focused argument, about “the fate of eloquence” in the modern [End Page 244] reconfiguration of society, through a variety of illustrations; as a result, the book has broad appeal to readers interested in literary contexts of rhetoric, gender, and culture.Situating Hume as the center of shared interest and assumption, Potkay defines an “Age of Hume,” a constellation of writers responding to and producing a tension between an ideal of classical eloquence and modern codes of politeness. Boldly establishing this tension “as the characteristic theme of the era,” Potkay makes a compelling case for politeness as the primary means of class stratification for emergent capitalist society. (Paul Fussell has also applied an eighteenth-century literary mind to contemporary sociology in his Class: A Guide Through the American Status System.) In his epilogue, Potkay brings his thesis home, to the ironies of academic publishing elitism and the “peculiarly American commitment to civic equality.”Several ruling assumptions guide Potkay’s treatment of the eloquence/politeness dualism. Reading high-canon writers and moral philosophers, Potkay defines eighteenth-century Britain as an age “that does not want its passions inflamed” and suspects eloquence of aiming to seduce the masses with rhetorical figures and physical gesture. Equated with popular government, eloquence threatens to manipulate “our untutored responses”—passions unmediated by moral and social education—within an exclusively “masculine” political economy. Echoing Christensen, Potkay finds “a characteristic irony” of the new “sentimental commerce” in the “polite restraint of the sexual passions that covertly fuel it” (p. 147). Writers must adapt to the paradigm shift of a new commercial and literary economy which included a sentimental ideal of woman as social sovereign—a model of polite literacy and civility which Hume described in his initial piece, “Of Essay Writing.”Potkay diffuses his gender-based thesis over a broad political and philosophical perspective. Politeness redressed the conflict between masculine populism (Bolingbroke) and effeminate luxury (Walpole) and “served to compensate for virtue lost through commercial progress” (p. 194). Potkay points out the ultimately political association of eloquence with vulgarity: savages, children, and the insane speak a language “thought to abound in figures”—a convenient habit in those whom a ruling class would exclude from “mature, rational discourse” (p. 68). (Here, Potkay elides the more complex “woman” from the above marginalia, for immediate reasons of either obviousness or neatness.)On the philosophical front Hume variously affirmed and problematized a “topos of eloquence as error.” Treatise-lovers may regret that he simmered this passionately figurative text down into the duller and drier Enquiries in order to fulfill a polite—and commercial—demand for the replacement of oral with written culture, of emotional gesticulation with “rationality, abstraction, logic” (p. 63). Potkay’s arguments suggest a ruling irony in this paradigm-shift: the association of eloquence (masculine) with emotionalism and politeness (feminine) with rationality and... (shrink)

Analogien lassen sich aus unserem vernünftigen Nachdenken und Argumentieren kaum wegdenken. Ganz zurecht stellen sie eines der klassischen Themen der Argumentationstheorie dar. Doch wie genau sollte die argumentative Rolle von Analogien in Argumentrekonstruktionen dargestellt werden? Das ist die Leitfrage dieses Beitrags. Zunächst wird mit Michael Dummetts Schach-Analogie ein prominentes Beispiel dargestellt und eine genauere Charakterisierung des Analogiebegriffs vorgeschlagen. Danach wird die gängigste Rekonstruktionsform von Analogien diskutiert, das Analogieargument, und in einigen Punkten verfeinert. Vor diesem Hintergrund schlägt der Beitrag eine zweite, (...) alternative Rekonstruktionsform vor, in der zwei analoge Argumente an die Stelle eines einzelnen Analogiearguments treten. Nachdem diese beiden Rekonstruktionsformen an einem weiteren berühmten Beispiel vorgeführt wurden, an Peter Singers Teich-Analogie, wird diskutiert, wie sich diese beiden Varianten gegenseitig ergänzen und welche Stärken und Schwächen sie haben. Es zeigt sich, dass Analogien nicht nur in Form von Analogieargumenten einen zentralen Topos eines Einzelarguments darstellen. Darüber hinaus kann die Untersuchung analoger Argumente bereits selbst als argumentationstheoretische Topik verstanden werden. (shrink)

Analogien lassen sich aus unserem vernünftigen Nachdenken und Argumentieren kaum wegdenken. Ganz zurecht stellen sie eines der klassischen Themen der Argumentationstheorie dar. Doch wie genau sollte die argumentative Rolle von Analogien in Argumentrekonstruktionen dargestellt werden? Das ist die Leitfrage dieses Beitrags. Zunächst wird mit Michael Dummetts Schach-Analogie ein prominentes Beispiel dargestellt und eine genauere Charakterisierung des Analogiebegriffs vorgeschlagen. Danach wird die gängigste Rekonstruktionsform von Analogien diskutiert, das Analogieargument, und in einigen Punkten verfeinert. Vor diesem Hintergrund schlägt der Beitrag eine zweite, (...) alternative Rekonstruktionsform vor, in der zwei analoge Argumente an die Stelle eines einzelnen Analogiearguments treten. Nachdem diese beiden Rekonstruktionsformen an einem weiteren berühmten Beispiel vorgeführt wurden, an Peter Singers Teich-Analogie, wird diskutiert, wie sich diese beiden Varianten gegenseitig ergänzen und welche Stärken und Schwächen sie haben. Es zeigt sich, dass Analogien nicht nur in Form von Analogieargumenten einen zentralen Topos eines Einzelarguments darstellen. Darüber hinaus kann die Untersuchung analoger Argumente bereits selbst als argumentationstheoretische Topik verstanden werden. (shrink)

The relevance of metamathematical researches for philosophy of math- ematics is an indubitable matter. In the paper I shall speak about impli- cations of metamathematics for general philosophy, especially for classical epistemological problems. Let us start with a historical observation con- cerning Hilbert's programme, the rst research programme in metamathe- matics as a separate study of formal systems. This programme was strongly in uence by epistemological considerations. In fact, Hilbert wanted to se- cure all classical mathematics against inconsistencies and this (...) aim had be achieved with the help of nitary consistency proof. Hilbert's claim is like the Cartesian project of reduction of all concepts to clarae et distinctae ideae. The epistemological commitment of original Hilbert's programme may be treated as a prelim- inary heuristic motivation for looking for epistemological implications of metamathematical results. It seems reasonable to examine in this respect three so-called limitative theorems: the rst Godel's incompleteness theo- rem , the second Godel's incom- pleteness theorem consistency of S, cannot be proved in S, providing that S is consistent) and Tarski's undenability theorem ; \S" stands for formal system containing elementary number theory. From the above-mentioned theorems we obtain an important, from philosophical point of view, conclusion: semantics of S cannot be expressed in S. Now, I shall present three applications of limitative theorems to the analysis of classical epistemological problems. (shrink)