All cells have electric potentials across their membranes, but is there really compelling evidence to think that such potentials are used as instructional cues in developmental biology? Numerous reports indicate that, in fact, steady, weak bioelectric fields are observed throughout biology and function during diverse biological processes, including development. Bioelectric fields, generated upon amputation, are also likely to play a key role during vertebrate regeneration by providing the instructive cues needed to direct migrating cells to form a wound epithelium, a (...) structure unique to regenerating animals. However, mechanistic insight is still sorely lacking in the field. What are the genes required for bioelectric‐dependent cell migration during regeneration? The power of genetics combined with the use of zebrafish offers the best opportunity for unbiased identification of the molecular players in bioelectricity. BioEssays 29:1133–1137, 2007. © 2007 Wiley Periodicals, Inc. (shrink)

My essay is devoted to the very early and attractive understanding of the lived body in Ortega y Gasset’s thought. I focus especially on the text “Vitality, Soul, Spirit” of 1925, which can be considered a proto-phenomenological approach to the issue of embodiment. Ortega identifies “vitality” with “the intrabody” and makes the latter the founding dimension of subjectivity, at the basis of the affective sphere (“soul”) and at the basis of the intellectual and volitional sphere (“spirit”). In a manner very (...) close to Husserl’s unpublished manuscripts, he also shows how the body is the only reality of which there is simultaneously external perception, as if it were just another thing in the world that everyone else can see, and internal perception, which only the self can have and feel. The study also points out, however, the two major difficulties that I detect in Ortega’s precocious attempt. A first doubt concerns the too sharp stratification of vitality, soul and spirit, as can be seen in the analysis of the experiences of pain and of mobility. A second doubt concerns the ontological hesitations surrounding Ortega’s position, which is torn between a coherent phenomenological perspective and a vitalist position in which my body is only an emanation of the lifestream of the universe. (shrink)

Databases play a fundamental role in today’s world, being used by most companies, especially those that offer services through the Internet. Today there is a wide variety of database models, each adapted for use according to the specific requirements of each application. Traditionally, the relational models with centralized architectures have been used mostly due to their simplicity and general-purpose query language, which made relational systems suitable for almost any application. However, with the growth of the Internet in recent decades, both (...) in the number of users and in the amount of information, those centralized models began to suffer availability and scalability issues. To address those issues, the use of decentralized architectures and alternative database models began to arise, eventually replacing relational databases and centralized architectures when the requirements on availability and scalability are high. Those database models alternative to the traditional relational model are grouped under the name of NoSQL. In this article, we present a NoSQL database developed as an end of degree work, with a flexible data model based on documents and a fully decentralized architecture based on the Gossip protocol for node discovery and a distributed hash table, in particular the rendezvous hashing algorithm, used to distribute and replicate the data across all the nodes. The main goals of the system are to achieve high availability and high scalability. High availability is achieved thanks to the replication of the data, while high scalability is achieved by its decentralized architecture, which allows multiple entry points from the requests, and the data distribution, effectively increasing the database capacity by increasing the number of nodes. (shrink)

Philosophia electiva -- Artículos, discursos, informes -- Cuaderno de consultas -- Escritos teológicos -- Traducciones -- Correspondencia.

Many pragmaticians have distinguished three levels of meaning involved in the comprehension of utterances, and there is an ongoing debate about how to characterize the intermediate level. Recanati has called it the level of ‘what is said’ and has opposed the idea that it can be determined semantically — a position that he labels ‘pragmatic minimalism’. To this end he has offered two chief arguments: semantic underdeterminacy and the Availability Principle. This paper exposes a tension between both arguments, relating this (...) discussion with Carruthers’s cognitive view of language, according to which some thoughts are, literally, sentences of our natural language. First we explain how this view entails minimalism, and we construct an argument based on semantic underdeterminacy that shows that natural language sentences do not have the compositional properties required to constitute thoughts. Then we analyze the example of a subject’s overhearing a sentence without an interpretive context, arguing that in the light of the Availability Principle the corresponding thought can be regarded as a natural language sentence. Thus, semantic underdeterminacy and availability pull in different directions, and we claim that there is no characterization of the latter that can relieve this tension. We contend that Recanati’s availability shares with Carruthers’s introspectivism an overreliance on intuitions about what appears consciously in one’s mind. We conclude, therefore, that the Availability Principle ought to be abandoned. (shrink)

Characterizations of autism include multiple references to rigid or inflexible features, but the notion of rigidity itself has received little systematic discussion. In this paper we shed some light on the notion of rigidity in autism by identifying different facets of this phenomenon as discussed in the literature, such as fixed interests, insistence on sameness, inflexible adherence to routines, black-and-white mentality, intolerance of uncertainty, ritualized patterns of verbal and non-verbal behavior, literalism, and discomfort with change. Rigidity is typically approached in (...) a disjointed fashion (i.e., facet by facet), although there are recent attempts at providing unifying explanations. Some of these attempts assume that the rigidity facets mainly relate to executive functioning: although such an approach is intuitively persuasive, we argue that there are equally plausible alternative explanations. We conclude by calling for more research on the different facets of rigidity and on how they cluster together in the autistic population, while suggesting some ways in which intervention could benefit from a finer-grained view of rigidity. (shrink)

Certain extensions of Nelson's constructive logic N with strong negation have recently become important in arti.cial intelligence and nonmonotonic reasoning, since they yield a logical foundation for answer set programming (ASP). In this paper we look at some extensions of Nelson's .rst-order logic as a basis for de.ning nonmonotonic inference relations that underlie the answer set programming semantics. The extensions we consider are those based on 2-element, here-and-there Kripke frames. In particular, we prove completeness for .rst-order here-and-there logics, and their (...) minimal strong negation extensions, for both constant and varying domains. We choose the constant domain version, which we denote by QNc5, as a basis for de.ning a .rst-order nonmonotonic extension called equilibrium logic. We establish several metatheoretic properties of QNc5, including Skolem forms and Herbrand theorems and Interpolation, and show that the .rst-oder version of equilibrium logic can be used as a foundation for answer set inference. (shrink)

In this work, Polo’s understanding of freedom is examined in all its dimensions: essential and personal freedom, extension and communication. I propose that the personalization of the innate habits corresponds with those which are called the encounters of transcendnetal freedom, which allows us to link Polian doctrin with that which San Josemaría left us about personal freedom.

Se realizó una revisión bibliográfica sobre el quehacer bioético contemporáneo e iberoamericano en el que continúa el debate abierto sobre las características de la bioética desarrollada en Iberoamérica y ofrece una razón de sus dificultades y desafíos. El objetivo es señalar la paradoja a la que se enfrenta la Bioética iberoamericana desde su particular contexto histórico, cultural y político. Esta paradoja se revela al tener que asimilar la bioética sanitaria estándar, surgida para hacer frente a problemas propios de la sociedad (...) occidental, con la finalidad de resolver problemas biosanitarios y sociales característicos de la región iberoamericana. Al objeto de explicar esta idea, se hace una breve presentación del desarrollo de la bioética contemporánea y se exponen las características de la bioética realizada en Iberoamérica como respuesta a la influencia de la bioética denominada estándar. It was carried out a bibliographic revision about the Iberoamerican contemporary bioethics tasks, in which the open debate about the characteristics of the bioethics developed in Iberoamerican offers a reason of its dificulties and challenges. The objective is to point out the paradox Iberoamerican bioethics faces since its own historical, cultural and political context. This paradox is reveleaded while having to assimilate the standard sanitary bioethics, risen with the aim to solve biosanitary and social problems typical of the wastern region. In order to explain this idea, it is made a brief presentation of the contemporary bioethics development and were exposed the characteistics of the bioethics carried out in Iberoamerica as and answer to the influence of the bioethics caled standard. (shrink)

In recent years ever-increasing concerns about ethical dimensions of fieldwork practice have forced anthropologists and other social scientists to radically reconsider the nature, process, and outcomes of fieldwork: what should we be doing, how, for whom, and to what end? In this volume, practitioners from across anthropological disciplines-social and biological anthropology and primatology-come together to question and compare the ethical regulation of fieldwork, what is common to their practices, and what is distinctive to each discipline. Contributors probe a rich variety (...) of contemporary questions: the new, unique problems raised by conducting fieldwork online and via email; the potential dangers of primatological fieldwork for locals, primates, the environment, and the fieldworkers themselves; the problems of studying the military; and the role of ethical clearance for anthropologists involved in international health programs. The distinctive aim of this book is to develop of a transdisciplinary anthropology at the methodological, not theoretical, level. (shrink)

También el dolor se dice de múltiples modos, se presenta de maneras muy diversas, adopta aspectos heterogéneos. Tantos que parece imposible su reducción a un único tipo básico o su dependencia genérica respecto de una forma fundamental que el pensamiento pudiera aprehender con ayuda de un solo concepto abarcador. Pero, por otra parte, en esta multiplicidad, en su dispersión prolífica, los muchos tipos de dolores tampoco llegan a fracturar una poderosa unidad de sentido, una inmediata afinidad interna entre ellos, que (...) reaviva el interés del pensamiento por habérselas con el dolor. (shrink)

En este artículo examinamos la última propuesta de Carruthers acerca del papel del lenguaje en cuanto emisor global de pensamientos en una arquitectura masivamente modular, centrándonos en dos aspectos: el habla interna como integrador intermodular y su función para explicar la creatividad de la cognición humana. En primer lugar argumentamos que el lenguaje no es suficiente para la integración intermodular, a partir de lo que llamamos el "problema de la audiencia": las oraciones compuestas por el módulo lingüístico, que incorporan información (...) de distintos dominios, son ininteligibles para cada módulo central, que es de dominio específico. Como alternativa, consideramos la posibilidad de que exista integración sin que sea llevada a cabo por ningún módulo en concreto. Finalmente sostenemos que la propuesta de Carruthers para el pensamiento creativo no respeta la fenomenología ni la ambigüedad del lenguaje. Defendemos que un sistema relacionado con la "lectura de mentes", cuya función es crucial para la comunicación lingüística, debe tener un papel mucho más importante. This paper examines Carruthers's latest proposal on the role of language as a global broadcaster of thoughts in a massively modular architecture. We focus on two aspects: inner speech as an intermodular integrator, and its function to explain creativity in human cognition. First, we argue that language is not sufficient for intermodular integration from what we call "the audience problem": sentences composed by the linguistic module, combining information from different domains, would be unintelligible to each central module, which is domain-specific. As an alternative, we consider the possibility that there is integration not carried out by a specific module. Finally, we claim that Carruthers's proposal for creative thinking respects neither the phenomenology nor the ambiguity of language. We contend that a mindreading system, which has a crucial function in linguistic communication, must have a much more important role to play. (shrink)

This debate on the duality of the human intellect "ut co-actus" is an inexhaustible and fathomless topic, reserved for the transcension of human thought. It suggests that the transcendental human intellect is on par with the knowledge that God has of each person, subject to the duality that forms the understanding and the being understood.

Este artículo investiga dos problemas principales en los conocidos argumentos de San Agustín en pro de la certeza, contra los escépticos. En realidad, son más bien dos niveles de una misma cuestión "metodológica": la interioridad del conocimiento y la reflexión, como vía de certeza. Conclusión principal de este estudio es que ambas dimensiones son correlativas: la reflexión supone interioridad, N la interioridad exige reflexión, como ría de certeza. La última parte del artículo examina la doctrina agustiniana de la reflexión, en (...) el contexto de su "filosofía del espíritu". La presente investigación intenta mostrar en este punto que, de hecho, San Agustín tematiza o supone, a lo largo de su obra tres grandes modos de reflexión, correspondientes a otros tantos modos de autoconocimiento del alma: el noticial, el cogitativo y el fenomenológico. (shrink)

Distensión de la finitud y belleza son paralelas en Agustín, su deducción y su calificación estética. Ontología de lo finito es, por ello, a la vez, discurso estético en tres grandes dimensiones: a) fundación y estructura de lo finito; b) sucesión temporal ; c) devenir histórico . Podríamos, sin reduccionismo alguno, interpretar su doctrina estética como >?.Distension of the finiteness and beauty are parallel in St. Augustine, its deduction and its aesthetic qualification. Ontology of finiteness is therefore, at the same (...) time, aesthetic thought in three dimensions: a) foundation and structure of the finetenesss; b) temporal succession ; c) historic becoming . Could we, with no reduction, interpret his aesthetic doctrine as >? (shrink)

El presente trabajo se enmarca en la propuesta fenomenológica de Jean Luc Marion, comenzando por la crítica que él realiza a Husserl y Heidegger. Luego de adentrarnos en lo fundamental de su propuesta fenomenológica, ‘cuanto de reducción, tanto de donación’, podremos acercarnos a comprender la llamada que genera y su fenomenalización por medio de la respuesta que se apila en nuestra carne. Frente a lo propuesto por Marion, esperamos encontrar una posibilidad de acercarnos a indicios del pensamiento filosófico de Cristo (...) sobre el rol del tercero y su testimonio. El trabajo se centra, por lo tanto, en los rastros que nos deja el pensamiento de Cristo, que puede ser esbozado a partir de una escapatoria al pensamiento griego. (shrink)

El autorrespeto se configura como una de las dimensiones morales más valiosas para la vida de una persona. Tanto es así que Rawls en la Teoría de la Justicia lo eleva a la categoría de bien primario más importante. El ser humano que se estima y respeta a sí mismo está dotando a su vida de un incalculable sentido moral y convierte su existencia en un proyecto pleno y meritorio. La autoestima proporciona al individuo un sentido de su propia valía (...) y le asegura la confianza necesaria para emprender y desarrollar un proyecto de vida significativo. La humillación y la vergüenza menoscaban las bases del autorrespeto y suponen un daño a la dignidad humana. (shrink)

According to the thesis of semantic underdetermination, most sentences of a natural language lack a definite semantic interpretation. This thesis supports an argument against the use of natural language as an instrument of thought, based on the premise that cognition requires a semantically precise and compositional instrument. In this paper we examine several ways to construe this argument, as well as possible ways out for the cognitive view of natural language in the introspectivist version defended by Carruthers. Finally, we sketch (...) a view of the role of language in thought as a specialized tool, showing how it avoids the consequences of semantic underdetermination. (shrink)

El presente trabajo analiza el libro Guión de Héctor Hernández Montecinos desde las perspectivas de flujo y de profanación para dar a conocer un tipo de producción poética que tensiona un problema del lenguaje: si el lenguaje es o no una representación de un sujeto que se asume en la escritura. Para este caso se postula que el sujeto que habla no se representa en el lenguaje. Lo que hay en esta lectura son solo residuos o devenires ficcionales de un (...) posible sujeto que se profana en el lenguaje. Por lo anterior, este lenguaje poético está expuesto como delirios mentales para hablar sobre poesía, historia y modos de entender la realidad. This paper analyzes Guión from the perspectives of flow and defilement to provide a kind of poetic production that stresses a problem of language: if the language is or is not a representation of a subject that is assumed in writing. For this case, it is postulated that the speaking subject is not represented in the language. What is in this reading are only residuals, or fictional becomings of a possible subject that is profaned in language. Therefore, this poetic language is exposed as mental delusions to speak about poetry, history and ways of understanding reality. (shrink)

The by now famous exclusion problem for mental causation admits only one possible solution, as far as I can see, namely: that mental and physical properties are linked by a vertical relation. In this paper, starting from what I take to be sensible premises about properties, I will be visiting some general relations between them, in order to see whether, first, it is true that some vertical relation, other than identity, makes different sorts of causation compatible and second, whether physical (...) and mental properties can be pairs of such relation. (shrink)