El autor toma las ideas fundamentales que los liberales han legado al mundo contemporáneo: la libertad y la propiedad fueron sus valores predilectos y su vigencia permanece hasta la actualidad. Empeñados en construir un Estado proclive a la libertad y la propiedad, los liberales idearon la soberanía, la separación de poderes y la posibilidad de que alguna vez hubiera Estados regidos por Constituciones. Hoy esas ideas constituyen los pilares de nuestra organización política.

El texto presenta algunas consideraciones acerca de las principales relaciones que se establecen en el momento presente entre la ética, la política y la educación, tres dimensiones fundamentales e interrelacionados en la existencia humana, analizándolas en su expresión en las circunstancias características de los ámbitos socioeconómico, político y cultural. A partir del análisis de estas interrelaciones, se pretende delinear algunas propuestas para una convivencia armónica y respetuosa entre los seres humanos en el siglo XXI, a través de una formación ciudadana (...) que posibilite la convivencia multicultural y el acceso a una auténtica sociedad del conocimiento. En este sentido, se examinan algunos de los dilemas y demandas éticos para alcanzar dichas formas de organización social ideales.The text presents some considerations about main relations that are established in the present moment, between ethics, politics and education, three essential and related dimensions in human existence, analyzing it in its characteristics expressions in the social, economic, cultural and political fields. Starting from the exam of those relations, it pretends to outline some proposals in order to get a harmonious and respectful coexistence between human beings in the XXI century, through a civic formation that makes possible multicultural coexistence and the access to an authentic knowledge society. In this sense, it examines some of the ethical dilemma and requests in order to access those ideal social organizations forms. (shrink)

In this article, the manuscript of Codex Madrid I, Leonardo da Vinci's workshop drawings collection, is reviewed and the main mechanisms that appear in the aforesaid codex are analysed. It begins with a short reference to Leonardo da Vinci works and, subsequently, Leonardo's manuscripts and Codex Madrid I, in particular, are placed in their historical context. After analysing the historical scope of Codex Madrid I, a compilation of the 100 main drawings of the manuscript is made, composing nine Mechanisms Drawings (...) Boxes. Each Mechanisms Drawings Box is a collage made up of 10 to 14 drawings of mechanical elements that appear in Codex Madrid I, with a brief description of each drawing. This compilation illustrates the wide range of mechanical elements and simple mechanisms of Codex Madrid I, forming, as a whole, a complete treatise on mechanisms, understanding mechanisms as basic elements of machines. (shrink)

En los primeros años del siglo XIV se planteó la polémica entre los franciscanos “espirituales” y el papa Juan XXII. El emperador alemán Luis de Baviera intervino en la confrontación a favor de los franciscanos y en contra del Papa. En la novela El nombre de la Rosa de Umberto Eco, se escenifica el conflicto entre el Franciscano Guillermo, que representa a Guillermo de Ockham y el inquisidor dominico Bernardo de Guí. En sus páginas se cita la filosofía de Aristóteles, (...) Tomás de Aquino Buenaventura de Bagnoregio, Marsilio de Padua y el propio Guillermo de Ockham. La filosofía política y el conocimiento científico de la época: Alberto Magno y Roger Bacon entre otros completan el panorama del citado siglo XIV. Todo ello demuestra una labor educativa incuestionable del libro de Umberto Eco. (shrink)

Mucopolysaccharidosis type I (MPS I) is a rare lysosomal storage disorder treated with bone marrow transplantation or enzyme replacement therapy with laronidase, a high-cost orphan drug. Laronidase was approved by the US Food and Drug Administration and the European Medicines Agency in 2003 and by the Brazilian National Health Surveillance Agency in 2005. Many Brazilian MPS I patients have been receiving laronidase despite the absence of a governmental policy regulating access to the drug. Epidemiological and treatment data concerning MPS I (...) are scarce. This study aims to present a demographic profile of Brazilian patients with MPS I, describe the routes of access to laronidase in Brazil, and discuss associated ethical issues relating to public funding of orphan drugs. (shrink)

Counting models for a two conjunctive formula $F$, a problem known as $\sharp $2Sat, is a classic $\sharp $P complete problem. Given a 2-CF $F$ as input, its constraint graph $G$ is built. If $G$ is acyclic, then $\sharp $2Sat can be computed efficiently. In this paper, we address the case when $G$ has cycles. When $G$ is cyclic, we propose a decomposition on the constraint graph $G$ that allows the computation of $\sharp $2Sat in incremental way. Let $T$ be (...) a cactus graph of $G$ containing a maximal number of independent cycles, and let $\overline{T}=-E)$ be a subset of frond edges from $G$. The clauses in $\overline{T}$ are ordered in connected components $\{K_1, \ldots, K_r\}$. Each $, i=1,\ldots,r$ is a knot of the graph. The arrangement of the clauses of $\overline{T}$ allows the decomposition of $G$ in knots and provides a way of computing $\sharp $2Sat in an incremental way. Our procedure has a bottom-up orientation for the computation of $\sharp $2Sat. It begins with $F_0 = T$. In each iteration of the procedure, a new clause $C_i \in \overline{T}$ is considered in order to form $F_i = $ and then to compute $\sharp $2Sat$$ based on the computation of $\sharp $2Sat$$. (shrink)

En las danzas rurales del norte de España pueden constatarse reminiscencias de carácter pagano. Dotadas de fuertes connotaciones sacras, su prevalencia y el interés de la juventud por secundarlas, sorprende en el entorno secular actual, de gran individualimos e hiperracional. De ahí el interés por entender los conflictos intergeneracionales surgidos en la actualidad, a través del estudio del caso de ‘La Gaita de Cervera del Río Alhama (La Rioja). Una danza que ha sido considerada marcial y que es sin (...) embargo, un conjunto de ritos sagrados de fertilidad, adaptados con la misma vocación pretérita de rito comunitario, petitorio y de tránsito. (shrink)

Los juegos de mesa son un producto cultural emergente estrechamente vinculado a actividades de aprendizaje informal sobre disciplinas variadas como la biología, las matemáticas o los idiomas. De entre estas áreas de conocimiento destaca la Historia, ya que desde el inicio del juego de mesa moderno hace 50 años se han publicado miles de juegos inspirados en las más diversas eras y hechos históricos, desde la Prehistoria hasta la Guerra Fría. Existe un interés académico creciente para desarrollar métodos de Aprendizaje (...) Basado en Juegos para aprovechar el potencial del juego como herramienta didáctica, pero la mayor parte se centra en el uso de videojuegos en el aula, y son escasos los trabajos que analizen el juego de mesa histórico en tanto que actividad de aprendizaje informal. Este trabajo explora el contenido histórico recreado en miles de juegos de mesa entendidos como motores de aprendizaje informal, con el objetivo de conocer qué temas de la Historia aparecen en juegos de mesa comerciales y, por tanto, son susceptibles de aprendizaje por parte de los jugadores. Para ello se ha desarrollado un método computacional basado en el modelado de tópicos y la visualización de datos para la identificación automática de temas en juegos de mesa a partir de sus descripciones textuales. El análisis presentado aquí se centra en un estudio comparativo de tres períodos con una escala diferente: a) la época Medieval, b) el siglo XIX, y c) Segunda Guerra Mundial. Los resultados del trabajo muestran como las temáticas tratadas en los juegos dependen directamente de la época en la que éstos se enmarcan, así como la existencia de marcados sesgos hacia la sobrerepresentación de guerras y la historia de Europa. Estas contribuciones sugieren que los juegos de mesa pueden promover el aprendizaje informal crítico sobre hechos históricos y al mismo tiempo reforzar una percepción pública desigual de nuestro pasado. (shrink)

BackgroundFunctional changes after spinal cord injury are related to changes in cortical plasticity. These changes can be measured with electroencephalography and has potential to be used as a clinical biomarker.MethodIn this longitudinal study participants underwent a total of 30 sessions of robotic-assisted gait training over a course of 6 weeks. The duration of each session was 30 min. Resting state EEG was recorded before and after 30-session rehabilitation therapy. To measure gait, we used the Walking Index for Spinal Cord Injury (...) Scale, 10-Meter- Walking Test, Timed-Up-and-Go, and 6-Min-Walking Test. Balance was measured using Berg Balance Scale.ResultsFifteen participants with incomplete SCI who had AIS C or D injuries based on American Spinal Cord Injury Association Impairment Scale classification were included in this study. Mean age was 35.7 years and the mean time since injury was 17.08 months. All participants showed clinical improvement with the rehabilitation program. EEG data revealed that high beta EEG activity in the central area had a negative correlation with gait and balance measured at baseline, in a way that greater high beta EEG power was related to worse clinical function at baseline. Moreover, improvement in gait and balance had negative correlations with the change in alpha/theta ratio in the parietal area.ConclusionIn SCI, functional impairment and subsequent improvement following rehabilitation therapy with RAGT correlated with the change in cortical activity measured by EEG. Our results suggest that EEG alpha/theta ratio may be a potential surrogate marker of functional improvement during rehabilitation. Future studies are necessary to improve and validate these findings as a neurophysiological biomarker for SCI rehabilitation. (shrink)

Thomas Aquinas wrote a text later known as Quaestio de attributis and ordered it inserted in a precise location of his Commentary on the Sentences of Peter Lombard more than a decade after composing this work. Aquinas assigned exceptional importance to this text, in which he confronts the debate on the issue of the divine attributes that swept the most important centres of learning in 13th Century Europe and examines the answers given to the problem by the representatives of the (...) four mainstream schools of his time: the Greek mystic Dionysius Areopagita, the Latin Saint Anselm of Canterbury, the Jewish rabbi Moses Maimonides and the Muslim philosopher Ibn Sina. This in-depth study of Thomas Aquinas’ Quaestio de attributis (In I Sent., d. 2, q. 1, a. 3) binds together the findings of previous research on the unique history of this text by reconstructing the historical circumstances surrounding its composition, shows that the Quaestio contains Aquinas’ final answer to the dispute on the divine attributes, and thoroughly examines his interpretation of Maimonides’ position on the issue of the knowledge of God by analysing this and other texts related to it chronologically and doctrinally. The examination of the Quaestio reveals the background of Thomas Aquinas’ renewed interest in Maimonides’ position on the issue and brings to light elements of Aquinas’ interpretation that are absent from his earlier references to Maimonides. Moreover, the chronological and doctrinal connection of the Quaestio de attributis to other Thomistic works with explicit references to Maimonides enables a reconstruction of his comprehensive approach to Maimonides’ teaching on the possibility and extent of the knowledge of God in the Guide of the Perplexed and highlights the place of Maimonides’ philosophical teachings in Thomas’ own thought in issues like "Being" as the proper name of God, the multiplicity of the divine names, the beatific vision in the afterlife, the causes that prevent the instruction of the multitude in divine matters and the role of faith and prophecy in the acquisition of the true knowledge of God in this life. The last chapter examines the reasons behind Aquinas’ silencing of Maimonides’ name when introducing his Five Ways for the knowledge of the existence of God, in spite of the evident relation between these and Maimonides’ Four Speculations. The study is completed with an extensive appendix that includes the text of the Quaestio de attributis with an English translation and the critical edition of several chapters of the 13th Century Latin translation of the Guide of the Perplexed known as Dux neutrorum. (shrink)

The aim of this article is to theorize how materials can play an active, constitutive, and causally effective role in the production and sustenance of cultural forms and meanings. It does so through an empirical exploration of the Museum of Modern Art of New York (MoMA). The article describes the museum as an “objectification machine” that endeavors to transform and to stabilize artworks as meaningful “objects” that can be exhibited, classified, and circulated. The article explains how the extent to which (...) the museum succeeds in this process of stabilization ultimately depends on the material properties of artworks and, more specially, on whether these behave as “docile” or “unruly” objects. Drawing on different empirical examples, the article explores how docile and unruly objects shape organizational dynamics within the museum and, through them, the wider processes of institutional and cultural reproduction. The article uses this empirical example to highlight the importance of developing a new “material sensibility” that restores heuristic dignity to the material within cultural sociology. (shrink)

Ames, Roger. Confucian Role Ethics: A Vocabulary. Honolulu: University of Hawai’i Press, 2011. 332 pp.

In the last few years, biologists and computer scientists have claimed that the introduction of data science techniques in molecular biology has changed the characteristics and the aims of typical outputs (i.e. models) of such a discipline. In this paper we will critically examine this claim. First, we identify the received view on models and their aims in molecular biology. Models in molecular biology are mechanistic and explanatory. Next, we identify the scope and aims of data science (machine learning in (...) particular). These lie mainly in the creation of predictive models which performances increase as data set increases. Next, we will identify a tradeoff between predictive and explanatory performances by comparing the features of mechanistic and predictive models. Finally, we show how this a priori analysis of machine learning and mechanistic research applies to actual biological practice. This will be done by analyzing the publications of a consortium—The Cancer Genome Atlas—which stands at the forefront in integrating data science and molecular biology. The result will be that biologists have to deal with the tradeoff between explaining and predicting that we have identified, and hence the explanatory force of the ‘new’ biology is substantially diminished if compared to the ‘old’ biology. However, this aspect also emphasizes the existence of other research goals which make predictive force independent from explanation. (shrink)

Summary The portrayal of Pontius Pilate as a single-handed prefect is one of the many incongruous and implausible elements found in the Gospel accounts of Jesus of Nazareth’s passion. Moreover, a striking imbalance in these accounts emerges: whilst Romans appear only at the last phase of the story, earlier the only people plotting against Jesus are Jews. There is every indication that some key information has been dropped. The present paper, after taking into account the traces of anti-Roman aspects in (...) Jesus’ career, surveys what is known about the consilia of Roman provincial governors and the sources of information available to them, and, for the first time, applies this knowledge to a critical reconstruction of the story underlying the Gospels, thereby providing a missing link to understand it. (shrink)

Ce livre résume une recherche que l'auteur a menée pendant de très longues années, et qu'il a voulu exposer comme élargissement de l'œuvre de William James, fondateur de la philosophie et de la psychologie américaines.

Toda imagen es un modo de mirar, de descubrir la realidad. La mirada del pintor o la del fotógrafo guarda para el futuro una parte, infinitesimal, del espacio. Solamente queda para la posteridad lo que ellos quieren que perdure. Las imágenes hablaron durante siglos acerca del pasado. Las pinturas retrataban las costumbres de la sociedad. La autoridad consagrada por el orden imperante resultaba reforzada por el arte canónico. Después de la invención de la fotografía las imágenes de guerra dejaron de (...) ser solamente un registro de gestas épicas. Este artículo busca presentar una perspectiva semiótica para leer una pintura sobre la guerra como un texto para lo cual propone cotejarla con una foto sobre el mismo tema.For a long time images spoke to society about the past. Paintings described different social groups' ways of life or moments like Amien's siege. Since the invention of photography the images of war didn't stand only for epic romances: photo could show the bare truth. The author proposes to look at a painting about the Paraguayan war as a text, trought a semiotic aproach. This allow us to know painter's cultural context and his ideological views. To make this possible, the author compares the painting with a photo on the same topic. (shrink)

An analysis of ms Vat. Lat. 781 reveals ratio and limppiditas as two key notions in Albert the Great's teaching on the possibility of knowing God.

In the last few years, biologists and computer scientists have claimed that the introduction of data science techniques in molecular biology has changed the characteristics and the aims of typical outputs (i.e. models) of such a discipline. In this paper we will critically examine this claim. First, we identify the received view on models and their aims in molecular biology. Models in molecular biology are mechanistic and explanatory. Next, we identify the scope and aims of data science (machine learning in (...) particular). These lie mainly in the creation of predictive models which performances increase as data set increases. Next, we will identify a tradeoff between predictive and explanatory performances by comparing the features of mechanistic and predictive models. Finally, we show how this a priori analysis of machine learning and mechanistic research applies to actual biological practice. This will be done by analyzing the publications of a consortium—The Cancer Genome Atlas—which stands at the forefront in integrating data science and molecular biology. The result will be that biologists have to deal with the tradeoff between explaining and predicting that we have identified, and hence the explanatory force of the ‘new’ biology is substantially diminished if compared to the ‘old’ biology. However, this aspect also emphasizes the existence of other research goals which make predictive force independent from explanation. (shrink)

Deep learning is a kind of machine learning which happens in a certain type of artificial neural networks called deep networks. Artificial deep networks, which exhibit many similarities with biological ones, have consistently shown human-like performance in many intelligent tasks. This poses the question whether this performance is caused by such similarities. After reviewing the structure and learning processes of artificial and biological neural networks, we outline two important reasons for the success of deep learning, namely the extraction of successively (...) higher level features and the multiple layer structure, which are closely related to each other. Then some indications about the framing of this heated debate are given. After that, an assessment of the value of artificial deep networks as models of the human brain is given from the similarity perspective of model representation. Finally, a new version of computational functionalism is proposed which addresses the specificity of deep neural computation better than classic, program based computational functionalism. (shrink)

From 1912, Alejandro Korn and José Ingenieros began to publish articles that then would be part of their historical works, respectively, Influencias filosóficas en la evolución nacional and La evolución de las ideas argentinas. Therefore, they started to generate some discussion in reference to sections that they knew of each other's work. Being the first major works from a developing philosophical field about the history of Argentine thought, their authors sought to create cultural traditions to affirm their own academic, cultural (...) and political positions. Thus, they based their positions about their academic situation through their interventions in the debate on the evaluation of the various features of the intellectual past of the country and national identity during the academic professionalization of historical studies, and actively participated in discussions on the function of culture and philosophy in a national project. Yet, besides, in order to address their history of ideas, the two most important teachers of the philosophical sphere around 1918 tested very different methodological approaches that worked under different conceptions of philosophical and historical practice and two different ways of thinking the reception and circulation of ideas from Europe. (shrink)

Background: Patients at the end-of-life and their families experience a strong emotional impact. The wellbeing of the patient at the end-of-life and their family caregiver are related. Aim: to explore the elements related with the emotional wellbeing of patients with and without cognitive impairment at the end-of-life and that of their primary family caregivers. Design: Cross- sectional study. Participants: data was collected from 202 patients at the end of life with different diagnosis (COPD, cancer and frail elderly) as well as (...) from their respective 202 primary family caregivers. Results: Structural equation models indicated that the emotional state of the patients was best predicted by their functional independence and the burden of their family caregivers. At the same time, the emotional state of the primary family caregiver was predicted by their burden and not by the cognitive state or the functional independence of the patient. Nevertheless, the burden of the family caregiver, which is the only variable predicting both the emotional state of the patient and that of the caregiver, was directly related with the functional independence of the patient and indirectly with the patient’s cognitive state. Conclusions: The burden of the family caregiver stands out as a key factor in the reduction of the emotional distress of patients at the end-of-life –whether or not they present significant cognitive impairment- and that of their family caregivers. (shrink)

El objetivo de este trabajo es dar cuenta de los conceptos de sujeto, subjetivación y ontología histórica de nosotros mismos. Estas categorías son esenciales en las pesquisas de Foucault de los años 80-84. De igual manera, desde estos conceptos, Foucault pudo pensar al sujeto de forma alterna al modo como este fue configurado en Occidente. En efecto, en sus intensas búsquedas encuentra en la tradición moderna, Baudelaire y Kant, pistas para considerar al sujeto no como un dato estático, sino como (...) alguien que se gestiona a través de procesos históricos que lo van delineando y que lo habilitan en la empresa de construirse, de elaborarse a sí mismo, esto es, mediante procesos de subjetivación. Finalmente, la tradición antigua, es decir, la tradición greco-latina, le ofrece elementos teóricos sustanciales para reflexionar sobre las condiciones en las que se pueden configurar modos de vida, estilos de existencia que operen como ejes de resistencia a las formas que se nos han impuesto. (shrink)

Self-determination theory considers motivation as a multidimensional phenomenon, with different levels of intensity, purposes, intentions, wills and autonomies. It distinguishes between intrinsic motivation, extrinsic motivation and amotivation. In this paper, we are going to focus on extrinsic motivation, which is related to those tasks that the subject performs without having a purpose in themselves, and which is composed of identified regulation, introjected regulation and external regulation. The aim of this research is to analyse the relationship between them and emotional intelligence (...) in 165 students with university degrees related to Physical Activity and Sport Sciences. The main findings of this work lie mainly in the demonstration of the fact that emotional intelligence is a predictor of identified regulation, introjected regulation and external regulation. (shrink)

Molinists hold that there are contingently true counterfactuals about what agents would do if put in specific circumstances, that God knows these prior to creation, and that God uses this knowledge in choosing how to create. In this essay we critique Molinism, arguing that if these theses were true, agents would not be free. Consider Eve’s sinning upon being tempted by a serpent. We argue that if Molinism is true, then there is some set of facts that fully explains both (...) Eve’s action and everything else Eve does that influences that action; and that if this is the case, Eve does not act freely. The first premise of this argument follows from the explanatory relations the Molinist is committed to, and the second premise follows from libertarian intuitions about free will. (shrink)

Although the correlation between Entrepreneurial Orientation and concrete actions to set up a business or the Probability of Starting a Business has been widely studied, the psychological factors that can affect this relationship have not yet been sufficiently addressed in the field of entrepreneurship. One of them is curiosity. Both at theoretical and empirical level, a distinction are usually made between two types of curiosity. I-type curiosity is associated with the anticipated pleasure of discovering something new, and D-type curiosity is (...) associated with reducing uncertainty and eliminating unwanted states of ignorance. Consequently, this paper aims to analyze the moderating role that the types of curiosity play in the relationship between EO and PSB, considering their interaction with sociodemographic variables. The sample of this cross-sectional study consisted of 1,761 participants. The EO scale and a curiosity scale were applied. In addition, participants were asked, based on their perception, how likely they were to start their own business within the next 5 years. A simple moderation analysis was considered to test the moderating role of both types of curiosity in the relationship between EO and PSB. Next, a double moderation analysis was carried out in order to identify, which sociodemographic variables moderate the moderating effect of curiosity. The results show that only the D-type component moderates the relationship between EO and PSB: The higher the D-type curiosity, the stronger the association between EO and PSB. In terms of sociodemographic variables, neither culture nor gender showed a moderating effect on the moderation exerted by D-type curiosity. While, age did moderate the moderating effect of D-type curiosity on the relationship between EO and PSB. Results are discussed in terms of spirituality and the resolution of problems associated with the entrepreneurial process, considering cognitive and psychological factors, particularly with an emphasis on explaining why only D-type curiosity shows a moderating effect. Finally, the limitations of the study and potential future lines of research are pointed out. (shrink)