Fecal microbiota transplantation has demonstrated efficacy and is increasingly being used in the treatment of patients with recurrent Clostridium difficile infection. Despite a lack of high-quality trials to provide more information on the long-term effects of FMT, there has been great enthusiasm about the potential for expanding its applications. However, FMT presents many serious ethical and social challenges that must be addressed as part of a successful regulatory policy response. In this article, we draw on a sample of the scientific (...) and bioethics literatures to examine clusters of ethical and social issues arising in five main areas: informed consent and the vulnerability of patients; determining what a “suitable healthy donor” is; safety and risk; commercialization and potential exploitation of vulnerable patients; and public health implications. We find that these issues are complex and worthy of careful consideration by health care professionals. Desperation of a patient should not be the basis for selecting treatment with FMT, and the patient's interests should always be of paramount concern. Authorities must prioritize development of appropriate and effective regulation of FMT to safeguard patients and donors, promote further research into safety and efficacy, and avoid abuse of the treatment. (shrink)

As new energy vehicle is the future of automobile development, it is of great significance to dig deeper into the technical topics and development trends of new energy vehicles for accurately understanding the technical trends of the new energy vehicle industry, grasping development opportunities, and scientifically formulating strategic plans. This paper takes the patent texts in the field of new energy vehicles from 2000 to 2020 in the patent database of CNKI as the data source, identifies 25 technical topics implied (...) in the patent texts by using the LDA topic model, analyzes the evolution trend of the 25 technical topics in terms of importance and popularity, and predicts the popularity and development trend of each technical topic in new energy vehicles from 2021 to 2025 by constructing the ARIMA model. The popularity and development trend of each technology topic of new energy vehicles in China from 2021 to 2025 are predicted by constructing ARIMA model. Drawing on quantitative evidence, the study found that there are top five technical topics in terms of importance in this field, namely, Topic 8, Topic 5, Topic 14, Topic 9, and Topic 15. From 2014 to 2020, the importances of Topic 5, Topic 8, Topic 6, Topic 9, and Topic 15 are gradually rising. In terms of popularity of technical topics, from 2014 to 2020, the first to fifth topics are Topic 20, Topic 8, Topic 3, Topic 15, and Topic 10. Based on the prediction of ARIMA model, it is found that the popularity of these five technical topics is steadily increasing from 2021 to 2025, among which the popularity of Topic 20 will increase from 63.58 to 113.07, the largest increase in popularity among all technical topics. The paper provides implications for countries dedicated to developing the new energy vehicle industry. (shrink)

Research in the fields of complex problem solving (CPS) and dynamic decision making using microworlds has been mainly conducted in Western industrialized countries. This study analyzes the CPS process by investigating thinking‐aloud protocols in five countries. Participants were 511 students from Brazil, Germany, India, the Philippines, and the United States who worked on two microworlds. On the basis of cultural‐psychological theories, specific cross‐national differences in CPS strategies were hypothesized. Following theories of situatedness of cognition, hypotheses about the specific frequency of (...) problem‐solving strategies in the two microworlds were developed. Results of the verbal protocols showed (a) modification of the theoretical CPS model, (b) task dependence of CPS strategies, and (c) cross‐national differences in CPS strategies. Participants’ CPS processes were particularly influenced by country‐specific problem‐solving strategies. (shrink)

Charles Peirce’s alpha system \ is reformulated into a deep inference system where the rules are given in terms of deep graphical structures and each rule has its symmetrical rule in the system. The proof analysis of \ is given in terms of two embedding theorems: the system \ and Brünnler’s deep inference system for classical propositional logic can be embedded into each other; and the system \ and Gentzen sequent calculus \ can be embedded into each other.

This book review symposium aims to open a space for discussions and questions responded to the book Education between Speech and Writing: Crossing the Boundaries of Dao and Deconstruction, which is...

Peirce wrote in late 1901 a text on formal logic using a special Dragon-Head and Dragon-Tail notation in order to express the relation of logical consequence and its properties. These texts have not been referred to in the literature before. We provide a complete reconstruction and transcription of these previously unpublished sets of manuscript sheets and analyse their main content. In the reconstructed text, Peirce is seen to outline both a general theory of deduction and a general theory of consequence (...) relation. The two are the cornerstones of modern logic and have played a crucial role in its development. From the wider perspective, Peirce is led to these theories by three important generalizations: propositions to all signs, truth to scriptibility, and derivation to transformability. We provide an exposition of such proposed semiotic foundation for logical constants and point out a couple of further innovations in this rare text, including the sheet of assertion, correction as a dual of deduction and the nature of conditionals as variably strict conditionals. (shrink)

Based on the expanded theory of planned behavior, this study first explores the configuration relationship between founder management and innovation by using the fuzzy-set qualitative comparative analysis. Based on the theory of planned behavior, this study divides the behavior intention of founders into three categories: Attitude, subjective norm, and perceived behavior control. Using fsQCA, we found that there are two ways to achieve high innovation input of enterprises. In combination with the two ways, the factors such as male and highly (...) educated founder, and large firm size can effectively increase the innovation input of firms, which is consistent with the three aspects of the behavioral intention of the theory of planned behavior, and it proves that the theory of planned behavior can effectively explain the configuration relation between the founder and firm innovation. In addition, this study finds that the innovation output is different from the innovation input, is dependent on the innovation ability of the firm itself, and is less influenced by the external environment. (shrink)

We argue that all general concepts are family resemblance concepts. These include concepts introduced by ostension, such as colour. Concepts of colour and of each of the specific colours are family resemblance concepts because similarities concerning an open-ended range of colour or of appearance features crop up and disappear. After discussing the notion of “same colour” and Wittgenstein's use of the phrase “our colours”, we suggest family resemblance concepts in one tradition can often be extended to family resemblance concepts in (...) another tradition, illustrated by Wittgenstein's use of the words Spiel and “game”. (shrink)

This paper presents a bioinspired lower extremity exoskeleton robot. The proposed exoskeleton robot can be adjusted in structure to meet the wearer’s height of 150–185 cm and has a good gait stability. In the gait control part, a method of identifying different locomotion modes is proposed; five common locomotion modes are considered in this paper, including sitting down, standing up, level-ground walking, ascending stairs, and descending stairs. The identification is depended on angle information of the hip, knee, and ankle joints. (...) A deep locomotion mode identification model based on long-short term memory architecture is proposed in this paper for exploiting the angle data. We conducted two experiments to verify the effectiveness of the proposed method. Experimental results show that the DLMIM is capable of learning inherent characteristics of joint angles and achieves more accurate identification than the other models. The last experiment demonstrates that the DLMIM can recognize transitions between different locomotion modes in time and the real-time performance varies with each individual. (shrink)

Background:Stigma is considered a major barrier to accessing healthcare services by female sex workers. Current knowledge of nurses’ attitudes appears to imply a stigma toward female sex workers. But in-depth understanding of their perceptions is scarce. Furthermore, factors that inform a conceptual understanding of how this occurs are lacking.Objectives:The study aimed to explore nurses’ attitudes toward female sex workers and factors affecting caring for female sex workers.Research design:This was a qualitative study. A content analysis approach was adopted in analyzing the (...) data.Participants and research context:Thirty-three practicing nurses participated in seven semi-structured focus group interviews and three key informants participated in three individual interviews in Hong Kong.Ethical considerations:This study was approved by the Ethics Committee of one university in Hong Kong.Findings:The findings revealed three themes: (1) accept, stigmatize, or against sex work; (2) reluctance, hesitation, or willingness to care for female sex workers; and (3) factors affecting the care of female sex workers.Discussion and conclusion:This study found that nurses held different attitudes toward female sex workers, and they experienced feelings of reluctance, hesitation, or willingness to care for female sex workers. Multi-level factors could affect their level of comfort of caring for female sex workers. Intervention should be developed to encourage health professionals to examine their personal views toward female sex workers introspectively, how their attitude may have affected the provision of quality services, and to enhance the provision of sensitive non-discriminative services to female sex workers. (shrink)

Because they are key components of aircraft, improving the safety, reliability and economy of engines is crucial. To ensure flight safety and reduce the cost of maintenance during aircraft engine operation, a prognostics and health management system that focuses on fault diagnosis, health assessment, and life prediction is introduced to solve the problems. Predicting the remaining useful life is the most important information for making decisions about aircraft engine operation and maintenance, and it relies largely on the selection of performance (...) degradation features. The choice of such features is highly significant, but there are some weaknesses in the current algorithm for RUL prediction, notably, the inability to obtain tendencies from the data. Especially with aircraft engines, extracting useful degradation features from multisensor data with complex correlations is a key technical problem that has hindered the implementation of degradation assessment. To solve these problems, deep learning has been proposed in recent years to exploit multiple layers of nonlinear information processing for unsupervised self-learning of features. This paper presents a deep learning approach to predict the RUL of an aircraft engine based on a stacked sparse autoencoder and logistic regression. The stacked sparse autoencoder is used to automatically extract performance degradation features from multiple sensors on the aircraft engine and to fuse multiple features through multilayer self-learning. Logistic regression is used to predict the remaining useful life. However, the hyperparameters of the deep learning, which significantly impact the feature extraction and prediction performance, are determined based on expert experience in most cases. The grid search method is introduced in this paper to optimize the hyperparameters of the proposed aircraft engine RUL prediction model. An application of this method of predicting the RUL of an aircraft engine with a benchmark dataset is employed to demonstrate the effectiveness of the proposed approach. (shrink)

Filosofía, praxis y emancipación -- Ética y alteridad -- Una ética con fundamento -- Por una ética emancipadora -- Ética y justicia -- Ética y pluralismo moral -- Ética y economía.

This study of internal auditors and auditees, who engage in both financial and operational internal audits in Israel, extends theory and research on internal audits in organizational units. It develops and tests a model that examines the role of top management and internal auditors in facilitating learning from internal audits and driving perceived performance improvement. We argue that support from the top management for the internal audit as well as the auditor’s capacity facilitate learning from audits and help audited units (...) to improve ethicality, efficiency, and effectiveness in organizations. The results of time-lagged survey data provide general support for the hypothesized indirect relationships between auditor capacity, auditor–auditee relational exchanges, learning from audits, and three different perceived performance measures: ethical behavior, efficiency, and effectiveness. We discuss the implications for research on internal audits, proactive learning, ethics, and performance improvement of organizational units in the public sector. (shrink)

Why should interpretation of conceptual schemes and practices across traditions work at all? In this paper we present the following necessary conditions of possibility for interpretation in comparative and Chinese philosophy: the interpreter must presuppose that there are mutually recognizable human practices; the interpreter must presuppose that “the other” is, on the whole, sincere, consistent, and right; the interpreter must be committed to certain epistemic virtues. Some of these necessary conditions are consistent with the fact that interpretation is not thwarted (...) by the “danger” of relativism or of incommensurability. Some other conditions are suggestive of reorientations of methodologies of comparative and Chinese philosophy. (shrink)

On the works of Ācārya Śrīrāma Śarmā, 1911-1990, Hindu philosopher.

Graded epistemic logic is a logic for reasoning about uncertainties. Graded epistemic logic is interpreted on graded models. These models are generalizations of Kripke models. We obtain completeness of some graded epistemic logics. We further develop dynamic extensions of graded epistemic logics, along the framework of dynamic epistemic logic. We give an extension with public announcements, i.e., public events, and an extension with graded event models, a generalization also including nonpublic events. We present complete axiomatizations for both logics.

Study on the fundamentals of Mimamsa philosophy.