The persistence of both inflammatory and neuropathic pain can only be explained when learning processes are taken into account in addition to sensitizing mechanisms. Learning processes such as classical and operant conditioning create memories for pain that are based on altered synaptic connections in supraspinal structures and persist without peripheral input. [coderre & katz; dickenson; wiesenfeld-hallin et al.].

Although the brain enables us to perceive the external world and our body, it remains unknown whether brain processes themselves can be perceived. Brain tissue does not have receptors for its own activity. However, the ability of humans to acquire self-control of brain processes indicates that the perception of these processes may also be achieved by learning. In this study patients learned to control low-frequency components of their EEG: the so-called slow cortical potentials (SCPs). In particular ''probe'' sessions, the patients (...) estimated the quality of the SCP shift they had produced in the preceding trial. The correspondence between the recorded SCP amplitudes and the subjective estimates increased with training. The ability to perceive the SCPs was related to the ability to control them; this perception was not mediated by peripheral variables such as changes in muscle tonus and cannot be reduced to simple vigilance monitoring. These data provide evidence that humans can learn to perceive the neural activity of their brain. Alternative interpretations are discussed. (shrink)

Psychopathic individuals are characterized by impaired affective processing, impulsivity, sensation-seeking, poor planning skills and heightened aggressiveness with poor self-regulation. Based on brain self-regulation studies using neurofeedback of Slow Cortical Potentials (SCPs) in disorders associated with a dysregulation of cortical activity thresholds and evidence of deficient cortical functioning in psychopathy, a neurobiological approach seems to be promising in the treatment of psychopathy. The results of our intensive brain regulation intervention demonstrate, that psychopathic offenders are able to gain control of their brain (...) excitability over fronto-central brain areas. After SCP self-regulation training, we observed reduced aggression, impulsivity and behavioral approach tendencies, as well as improvements in behavioral-inhibition and increased cortical sensitivity for error-processing. This study demonstrates improvements on the neurophysiological, behavioral and subjective level in severe psychopathic offenders after SCP-neurofeedback training and could constitute a novel neurobiologically-based treatment for a seemingly change-resistant group of criminal psychopaths. (shrink)

A common adage runs that, given a theory manifesting symmetries, the syntax of that theory should be modified in order to construct a new theory, from which symmetry-variant structure of the original theory has been excised. Call this strategy for explicating the underlying ontology of symmetry-related models reduction. Recently, Dewar has proposed an alternative to reduction as a means of articulating the ontology of symmetry-related models—what he calls sophistication, in which the semantics of the original theory is modified, and symmetry-related (...) models of that theory are treated as if they are isomorphic. In this paper, we undertake a critical evaluation of sophistication about symmetries—we find the programme underdeveloped in a number of regards. In addition, we clarify the interplay between sophistication about symmetries, and a separate debate to which Dewar has contributed—viz., that between interpretational versus motivational approaches to symmetry transformations. (shrink)

Electronic text can be defined on two different, though interconnected, levels. On the one hand, electronic text can be defined by taking the notion of “text” or “printed text” as the point of departure. On the other hand, electronic text can be defined by taking the digital format as the point of departure, where everything is represented in the binary alphabet. While the notion of text in most cases lends itself to being independent of medium and embodiment, it is also (...) often tacitly assumed that it is in fact modeled on the print medium, instead of, for instance, on hand-written text or speech. In late 20th century, the notion of “text” was subjected to increasing criticism, as can be seen in the question that has been raised in literary text theory about whether “there is a text in this class.” At the same time, the notion was expanded by including extralinguistic sign modalities (images, videos). A basic question, therefore, is whether electronic text should be included in the enlarged notion that text is a new digital sign modality added to the repertoire of modalities or whether it should be included as a sign modality that is both an independent modality and a container that can hold other modalities. In the first case, the notion of electronic text would be paradigmatically formed around the e-book, which was conceived as a digital copy of a printed book but is now a deliberately closed work. Even closed works in digital form will need some sort of interface and hypertextual navigation that together constitute a particular kind of paratext needed for accessing any sort of digital material. In the second case, the electronic text is defined by the representation of content and (some parts of the) processing rules as binary sequences manifested in the binary alphabet. This wider notion would include, for instance, all sorts of scanning results, whether of the outer cosmos or the interior of our bodies and of digital traces of other processes in-between (machine readings included). Since other alphabets, such as the genetic alphabet and all sorts of images may also be represented in the binary alphabet, such materials will also belong to the textual universe within this definition. A more intriguing implication is that born-digital materials may also include scripts and interactive features as intrinsic parts of the text. The two notions define the text on different levels: one is centered on the Latin, the other on the binary alphabet, and both definitions include hypertext, interactivity, and multimodality as constituent parameters. In the first case, hypertext is included as a navigational, paratextual device; whereas in the second case, hypertext is also incorporated in the narrative within an otherwise closed work or as a constituent element on the textual universe of the web, where it serves the ongoing production of (possibly scripted) connections and disconnections between blocks of textual content. Since the early decades of early 21st century still represent only the very early stages of the globally distributed universe of web texts, this is also a history of the gradual unfolding of the dimensions of these three constituencies—hypertext, interactivity, and multimodality. The result is a still-expanding repertoire of genres, including some that are emerging via path dependency; some via remediation; and some as new genres that are unique for networked digital media, including “social media texts” and a growing variety of narrative and discursive multiple-source systems. (shrink)

Absolutism about mass claims that mass ratios obtain in virtue of absolute masses. Comparativism denies this. Dasgupta, Oxford studies in metaphysics, Oxford University Press, Oxford, 2013) argues for comparativism about mass, in the context of Newtonian Gravity. Such an argument requires proving that comparativism is empirically adequate. Dasgupta equates this to showing that absolute masses are undetectable, and attempts to do so. This paper develops an argument by Baker to the contrary: absolute masses are in fact empirically meaningful, that is (...) detectable. Additionally, it is argued that the requirement of empirical adequacy should not be cashed out in terms of undetectability in the first place. The paper closes by sketching the possible strategies that remain for the comparativist. Along the way a framework is developed that is useful for thinking about these issues: Ozma games—how could one explain to an alien civilisation what an absolute mass is? (shrink)

These articles and speeches by the Nobel Prize-winning physicist date from 1934 to 1958. Rather than expositions on quantum physics, the papers are philosophical in nature, exploring the relevance of atomic physics to many areas of human endeavor. Includes an essay in which Bohr and Einstein discuss quantum and_wave equation theories. 1961 edition.

Research on work values shows that respectful leadership is highly desired by employees. On the applied side, however, the extant research does not offer many insights as to which concrete leadership behaviors are perceived by employees as indications of respectful leadership. Thus, to offer such insights, we collected and content analyzed employees’ narrations of encounters with respectful leadership (N1 = 426). The coding process resulted in 19 categories of respectful leadership spanning 149 leadership behaviors. Furthermore, to also harness this comprehensive (...) repertoire for quantitative organizational research, we undertook two more studies (N2a = 228; N2b = 412) to empirically derive a feasible item-based measurement of respectful leadership and assess its psychometric qualities. In these studies, we additionally investigated the relationships between respectful leadership as assessed with this new measurement and employees’ vertical and contextual followership as assessed via subordinates’ identification with their leaders, their appraisal respect for their leaders, their feeling of self-determination, and their job satisfaction. (shrink)

The introduction of Autonomous Military Systems (AMS) onto contemporary battlefields raises concerns that they will bring with them the possibility of a techno-responsibility gap, leaving insecurity about how to attribute responsibility in scenarios involving these systems. In this work I approach this problem in the domain of applied ethics with foundational conceptual work on autonomy and responsibility. I argue that concerns over the use of AMS can be assuaged by recognising the richly interrelated context in which these systems will most (...) likely be deployed. This will allow us to move beyond the solely individualist understandings of responsibility at work in most treatments of these cases, toward one that includes collective responsibility. This allows us to attribute collective responsibility to the collectives of which the AMS form a part, and to account for the distribution of burdens that follows from this attribution. I argue that this expansion of our responsibility practices will close at least some otherwise intractable techno-responsibility gaps. (shrink)

v. 1. Atomic theory and the description of nature -- v. 2. Essays 1932-1957 on atomic physics and human knowledge -- v. 3. Essays 1958-1962 on atomic physics and human knowledge -- v. 4. Causality and complementarity.

Introductory survey -- Atomic theory and mechanics -- The quantum postulate and the recent development of atomic theory -- The quantum of action and the description of nature -- The atomic theory and the fundamental principles underlying the description of nature.

Absolutism about mass within Newtonian gravity claims that mass ratios obtain in virtue of absolute masses. Comparativism denies this. Defenders of comparativism promise to recover all the empirical and theoretical virtues of absolutism, but at a lower ‘metaphysical cost’. This article develops a Machian form of comparativism about mass in Newtonian gravity, obtained by replacing Newton’s constant in the law of universal gravitation by another constant divided by the sum over all masses. Although this form of comparativism is indeed empirically (...) equivalent to the absolutist version of Newtonian gravity—thereby meeting the challenge posed by the comparativist’s bucket argument—it is argued that the explanatory power and metaphysical parsimony of comparativism are highly questionable. (shrink)

Ideals (or ideal values) help people to navigate in social life. They indicate at a very fundamental level what people are concerned about, what they strive for, and what they want to be affiliated with. Transferring this to a leader–follower analysis, our first study (n = 306) confirms that followers’ identification and satisfaction with their leaders are stronger, the more leaders match followers’ ideal leader values. Study 2 (n = 244) extends the perspective by introducing the novel concept of counter-ideals (...) (i.e., how an ideal leader should not be) as a second, non-redundant point of reference. Results confirm that a leader’s match on ideal and on counter-ideal values have independent effects in that both explain unique variance in followers’ identification and satisfaction with their leader. Study 3 (n = 136) replicates the previous results in an experimental scenario study and provides evidence for the proposed causal direction of the underlying process. We conclude that counter-ideal values might be an additional point of reference that people use to triangulate targets above and beyond ideal values and discuss the implications of our findings for value research and management. (shrink)

Across the European research area and beyond, efforts are being mobilized to align research and innovation processes and products with societal values and needs, and to create mechanisms for inclusive priority setting and knowledge production. A central concern is how to foster a culture of “Responsible Research and Innovation” among scientists and engineers. This paper focuses on RRI teaching at higher education institutions. On the basis of interviews and reviews of academic and policy documents, it highlights the generic aspects of (...) teaching aimed at invoking a sense of care and societal obligation, and provides a set of exemplary cases of RRI-related teaching. It argues that the Aristotelian concept of phronesis can capture core properties of the objectives of RRI-related teaching activities. Teaching should nurture the students’ capacity in terms of practical wisdom, practical ethics, or administrative ability in order to enable them to act virtuously and responsibly in contexts which are often characterized by uncertainty, contention, and controversy. (shrink)

Systemic therapy considers the complex dynamics of relational factors and resources contributing to psychological symptoms. Negative maintaining factors have been well researched for people suffering from Alcohol-use Disorders. However, we know little about the complex dynamics of these negative factors and resources. We interviewed fifty-five participants suffering or fully remitted from Alcohol-use disorders in this cross-sectional study. The interviews focused on relational factors referring to a Support Social Network and a Craving Social Network. The CSN included all significant others who (...) were associated with craving situations. We compared the network characteristics of the group suffering from Alcohol-use Disorders to a fully remitted control group. The abstinent group with full remission named on average fewer individuals in the CSNs. They had lower social negativity mean scores in the Support Social Network compared to the non-remitted group. In the CSN, the mean scores of social support were significantly higher than the median for both groups. These findings reveal the complex interplay of relational patterns contributing to the etiology, maintenance, and recovery from Alcohol-use disorders. A successful recovery can be linked to increased social resources and reduced relations associated with craving. However, craving-associated relations represent an important source of social support. Future research should investigate this ambivalence for the systemic perspective on the explanation and treatment of Alcohol-use disorders. (shrink)

The article presents a conceptual framework for distinguishing different sorts of heterogeneous digital materials. The hypothesis is that a wide range of heterogeneous data resources can be characterized and classified due to their particular configurations of hypertext features such as scripts, links, interactive processes, and time scalings, and that the hypertext configuration is a major but not sole source of the messiness of big data. The notion of hypertext will be revalidated, placed at the center of the interpretation of networked (...) digital media, and used in the analysis of the fast-growing amounts of heterogeneous digital collections, assemblages, and corpora. The introduction summarizes the wider background of a fast-changing data landscape. (shrink)

On several occasions I have pointed out that the lesson taught us by recent developments in physics regarding the necessity of a constant extension of the frame of concepts appropriate for the classification of new experiences leads us to a general epistemological attitude which might help us to avoid apparent conceptual difficulties in other fields of science as well. Since, however, the opinion has been expressed from various sides that this attitude would appear to involve a mysticism incompatible with the (...) true spirit of science, I am very glad to use the present opportunity of addressing this assembly of scientists working in quite different fields but united in their striving to find a common ground for our knowledge, to come back to this question, and above all to try to clear up the misunderstandings which have arisen. (shrink)

SummaryA short exposition is given of the foundation of the causal description in classical physics and the failure of the principle of causality in coping with atomic phenomena. It is emphasized that the individuality of the quantum processes excludes a separation between a behaviour of the atomic objects and their interaction with the measuring instruments denning the conditions under which the phenomena appear. This circumstance forces us to recognize a novel relationship, conveniently termed complementarity, between empirical evidence obtained under different (...) experimental conditions. An appropriate tool for a complementary mode of description is provided by the quantum‐mechanical formalism which allows us to account for regularities of definite or statistical character beyond the grasp of classical physical explanation. – N. B. (shrink)

Previous studies of auditory expectation have focused on the expectedness perceived by listeners retrospectively in response to events. In contrast, this research examines predictive uncertainty —a property of listeners' prospective state of expectation prior to the onset of an event. We examine the information-theoretic concept of Shannon entropy as a model of predictive uncertainty in music cognition. This is motivated by the Statistical Learning Hypothesis, which proposes that schematic expectations reflect probabilistic relationships between sensory events learned implicitly through exposure. Using (...) probability estimates from an unsupervised, variable-order Markov model, 12 melodic contexts high in entropy and 12 melodic contexts low in entropy were selected from two musical repertoires differing in structural complexity (simple and complex). Musicians and non-musicians listened to the stimuli and provided explicit judgments of perceived uncertainty (explicit uncertainty). We also examined an indirect measure of uncertainty computed as the entropy of expectedness distributions obtained using a classical probe-tone paradigm where listeners rated the perceived expectedness of the final note in a melodic sequence (inferred uncertainty). Finally, we simulate listeners' perception of expectedness and uncertainty using computational models of auditory expectation. A detailed model comparison indicates which model parameters maximize fit to the data and how they compare to existing models in the literature. The results show that listeners experience greater uncertainty in high-entropy musical contexts than low-entropy contexts. This effect is particularly apparent for inferred uncertainty and is stronger in musicians than non-musicians. Consistent with the Statistical Learning Hypothesis, the results suggest that increased domain-relevant training is associated with an increasingly accurate cognitive model of probabilistic structure in music. (shrink)

The empirical coherence problem of quantum gravity is the worry that a theory which does not fundamentally contain local beables located in space and time—such as is arguably the case for certain approaches to quantum gravity—cannot be connected to measurements and thus has its prospects of being empirically adequate undermined. Spacetime functionalism à la Lam and Wüthrich is said to solve this empirical coherence problem as well as bridging a severe conceptual gap between spatiotemporal structures of classical spacetime theories on (...) the one hand, and the non-spatiotemporal structures in quantum gravity approaches on the other hand. The aim of this essay is to offer a deflationary account of both the empirical coherence problem and the spatiotemporal gap problem as they are claimed to arise at least prima facie for current theories of quantum gravity by Huggett and Wüthrich :276–285, 2013), Lam and Wüthrich and Le Bihan. I defend the view that spacetime functionalism is set up to address a problem which can usually be solved without it; and that it is wrongly claimed to solve another problem which for any actual account of quantum gravity is in fact currently non-existent anyway. (shrink)

We discuss the status of gravitational radiation in Newtonian theories. In order to do so, we consider various options for interpreting the Poisson equation as encoding propagating solutions, reflect on the extent to which limit considerations from general relativity can shed light on the Poisson equation’s conceptual status, and discuss various senses in which the Poisson equation counts as a dynamical equation.

Open peer commentary on the target article “Who Conceives of Society?” by Ernst von Glasersfeld. Excerpt: In the face of modern neuroscience we should give up on constructivism, even more so on radical constructivism, and stick to the physical and psychological reality given in science and daily life, even if it is the brain’s illusion from associative networks. The illusion of constructivism may hurt!

The empirical coherence problem of quantum gravity is the worry that a theory which does not fundamentally contain local beables located in space and time—such as is arguably the case for certain approaches to quantum gravity—cannot be connected to measurements and thus has its prospects of being empirically adequate undermined. Spacetime functionalism à la Lam and Wüthrich is said to solve this empirical coherence problem as well as bridging a severe conceptual gap between spatiotemporal structures of classical spacetime theories on (...) the one hand, and the non-spatiotemporal structures in quantum gravity approaches on the other hand. The aim of this essay is to offer a deflationary account of both the empirical coherence problem and the spatiotemporal gap problem as they are claimed to arise at least prima facie for current theories of quantum gravity by Huggett and Wüthrich :276–285, 2013), Lam and Wüthrich and Le Bihan. I defend the view that spacetime functionalism is set up to address a problem which can usually be solved without it; and that it is wrongly claimed to solve another problem which for any actual account of quantum gravity is in fact currently non-existent anyway. (shrink)

Comparativism—the view that mass ratios are not grounded in absolute masses—faces a challenge by Baker which suggests that absolute masses are empirically meaningful. Regularity comparativism uses a liberalized version of the Mill-Ramsey-Lewis Best Systems Account to have both the laws of Newtonian gravity and the absolute mass scale supervene on a comparativist Humean mosaic as a package deal. I discuss three objections to this view and conclude that it is untenable. The most severe problem is that once we have reduced (...) away the absolute masses, there is nothing that stops us from also reducing the mass ratios. (shrink)

This thesis concerns the metaphysics of scale. It investigates the implications of a physical determinable being dimensionful. In particular, it considers the case study of mass, as it features within Newtonian Gravity. Nevertheless, most of the terminology, methodology and arguments developed should be relatively straightforwardly applicable to other determinables and theories. -/- Weak Absolutism about mass holds that mass ratios obtain in virtue of absolute masses. Weak Comparativism denies this. In the first five chapters I argue in favour of Weak (...) Absolutism over Weak Comparativism. The sixth chapter argues against reducing mass to other non-mass facts. The overall conclusion is Strong Absolutism about mass within Newtonian Gravity: mass ratios obtain in virtue of absolute masses, which themselves are fundamental (i.e. they do not require anything further in order to obtain). -/- Comparativism promises to recover all the virtues of absolutism, in particular its empirical adequacy, but at a lower 'metaphysical cost'. Special attention is given to Dasgupta's recent comparativist proposal. Dasgupta interprets the requirement of empirical adequacy in terms of the undetectability of the absolute mass scale. I argue that undetectability is an unsuitable way of understanding empirical adequacy and that we would do better to understand it in terms of a theory's ability to correctly generate the set of empirically possible worlds (or at least the actual world). I refute Dasgupta's comparativism both on my terms and on his own terms. I subsequently develop and strongly criticise alternative versions of comparativism. Chapter five sheds doubt on the supposed 'metaphysical parsimony' of comparativism. -/- This debate should be of particular interest to readers who engage with the substantivalism-relationalism debate. These debates are much more entwined than previously acknowledged, which provides a significant source of mutual inspiration, although I do also draw out some important disanalogies. -/- . (shrink)

Der erste Andronikos erwies sich unter jenen Kaisern, welchen auf dem Thron des byzantinischen Reiches nur eine kurze Zeitspanne beschieden war, als besonderer Liebling der Nymphe Echo. Geboren um 1120, tritt dieser kaiserliche Neffe und Ziehbruder eines Kaisers als eine im wahren Wortsinn changierende Gestalt des 12. Jahrhunderts vor unsere Augen. Zeitlebens war er der vornehmste Opponent seines Vetters, des Kaisers Manuel Komnenos (reg. 1143–1180); er verbrachte neun Jahre im Kerker (1154/55–Herbst 1164) und lebte nach abenteuerlicher Flucht für weitere fünfzehn (...) Jahre in Verbannung (1164/65, 1166–1180). Als er spät im Jahr 1183 schließlich zum Basileus der Rhomäer avancierte, schreckte er vor dem Meuchelmord an seinem Neffen, dem jungen Kaiser Alexios, nicht zurück – um seinerseits kaum zwei Jahre später von Hand des konstantinopolitanischen Pöbels das wohl grausamste Ende zu finden, das jemals einem byzantinischen Autokrator zuteil wurde (September 1185): Das prophezeite AIMA der Komnenoi hatte sich erfüllt. Andronikos' kurze Tyrannis ist eingerahmt von den blutigen Ausschreitungen der Konstantinopolitaner wider die Lateiner (April 1182) und deren Nemesis, der normannischen Eroberung und Plünderung Thessalonikes (August 1185). Einige beherzte Maßnahmen seinerseits, groben Mißständen Abhilfe zu leisten, wurden bereits von den Zeitgenossen mit Lob bedacht. Die folgenden Glossen richten den Fokus allerdings vor allem auf jene Jahre, in denen odysseusgleiche Irrfahrten Andronikos bis hinauf in die Lande der Rus' (1164/65) und schließlich von Jerusalem über Damaskus und Bagdad nach Georgien führten (zwischen 1167 und 1180), ehe er in der Herrschaft der Saltuḳ-oġullari im nordöstlichen Winkel Kleinasiens, bei Koloneia (türk. Şebinkarahisar), Zuflucht fand. (shrink)