Once a neural implant has shown some efficacy during initial research trials, it begins to enter the world of clinical application. This culminates when the implant becomes approved for a particular indication. However, the ethical challenges continue as the technology is adopted as a standard of practice. Patient eligibility criteria, as documented by inclusion and exclusion criteria with any new treatment, are not always clearly quantified and defined. These vagaries can result in considerable debate regarding who should or should not (...) proceed with surgery. There is often considerable room for clinical judgment that can result in extension of the treatment to a wider range of patients. The ethical questions that arise in clinical decisionmaking differ significantly from those inherent in engineering design and research development. (shrink)

This paper deals with Care of the Self under globalization. The first part refers to Johann P. Arnason’s interpretation of Jan Patočka’s work on super-civilization and shows the contradictions facing people in the Modern Era. It suggests that the concept of moderateness is an adequate point of departure for handling the various contradictions of the current epoch. The second part looks at selected aspects of Confucian philosophy in which moderateness, that is, the permanent search for a “middle position” is an (...) integral part of that philosophical tradition. The critical actualisation of Confucianism as proposed for instance by Heiner Roetz is seen as an appropriate way of developing the dialogical characteristics of Confucian philosophy. In the last part it is stressed that critical theory is of relevance when identifying various forms of suffering and because of its ability to understand and critically evaluate diverse cultural and social contexts. (shrink)

Gilbert and colleagues point out the discrepancy between the limited empirical data illustrating changes in personality following implantation of deep brain stimulating electrodes and the vast number of conceptual neuroethics papers implying that these changes are widespread, deleterious, and clinically significant. Their findings are reminiscent of C. P. Snow’s essay on the divide between the two cultures of the humanities and the sciences. This division in the literature raises significant ethical concerns surrounding unjustified fear of personality changes in the context (...) of DBS and negative perceptions of clinician-scientists engaged in DBS. These concerns have real world implications for funding future innovative, DBS trials aimed to reduce suffering as well as hampering true interdisciplinary scholarship. We argue that the philosophical tradition of pragmatism and the value it places on empirical inquiry, experiential knowledge, and inter-disciplinary scholarship – reflecting diverse ways of knowing – provides a framework to start to address the important questions Gilbert and colleagues raise. In particular, we highlight the importance of expert clinician knowledge in contributing to the neuroethical questions raised by Gilbert and colleagues. Finally, we provide illustrative examples of some of our interdisciplinary empirical research that demonstrate the iterative cycle of inquiry characteristic of pragmatism in which conceptual neuroethics questions have led to empirical studies whose results then raise additional conceptual questions that give rise to new empirical studies in a way that highlights the contributions of the humanities and the sciences. (shrink)

Starting with a review of research on love as an emotion, with an emphasis on romantic love, it is argued that despite strong emotional correlates evidence is lacking to conclude that love would meet the criteria of basic emotions. Theoretical developments are proposed where love is conceived of as a combination of an objectless drive, a desire for love, and a mythical and scripted representation that offers the possibility of labeling the current core affect. I argue that the basic motive (...) for love is not so much the partner’s personal attributes, but rather the benefits of the transformative power of being in love. (shrink)

Gilbert and colleagues point out the discrepancy between the limited empirical data illustrating changes in personality following implantation of deep brain stimulating electrodes and the vast number of conceptual neuroethics papers implying that these changes are widespread, deleterious, and clinically significant. Their findings are reminiscent of C. P. Snow’s essay on the divide between the two cultures of the humanities and the sciences. This division in the literature raises significant ethical concerns surrounding unjustified fear of personality changes in the context (...) of DBS and negative perceptions of clinician-scientists engaged in DBS. These concerns have real world implications for funding future innovative, DBS trials aimed to reduce suffering as well as hampering true interdisciplinary scholarship. We argue that the philosophical tradition of pragmatism and the value it places on empirical inquiry, experiential knowledge, and inter-disciplinary scholarship – reflecting diverse ways of knowing – provides a framework to start to address the important questions Gilbert and colleagues raise. In particular, we highlight the importance of expert clinician knowledge in contributing to the neuroethical questions raised by Gilbert and colleagues. Finally, we provide illustrative examples of some of our interdisciplinary empirical research that demonstrate the iterative cycle of inquiry characteristic of pragmatism in which conceptual neuroethics questions have led to empirical studies whose results then raise additional conceptual questions that give rise to new empirical studies in a way that highlights the contributions of the humanities and the sciences. (shrink)

Gilbert and colleagues point out the discrepancy between the limited empirical data illustrating changes in personality following implantation of deep brain stimulating electrodes and the vast number of conceptual neuroethics papers implying that these changes are widespread, deleterious, and clinically significant. Their findings are reminiscent of C. P. Snow’s essay on the divide between the two cultures of the humanities and the sciences. This division in the literature raises significant ethical concerns surrounding unjustified fear of personality changes in the context (...) of DBS and negative perceptions of clinician-scientists engaged in DBS. These concerns have real world implications for funding future innovative, DBS trials aimed to reduce suffering as well as hampering true interdisciplinary scholarship. We argue that the philosophical tradition of pragmatism and the value it places on empirical inquiry, experiential knowledge, and inter-disciplinary scholarship – reflecting diverse ways of knowing – provides a framework to start to address the important questions Gilbert and colleagues raise. In particular, we highlight the importance of expert clinician knowledge in contributing to the neuroethical questions raised by Gilbert and colleagues. Finally, we provide illustrative examples of some of our interdisciplinary empirical research that demonstrate the iterative cycle of inquiry characteristic of pragmatism in which conceptual neuroethics questions have led to empirical studies whose results then raise additional conceptual questions that give rise to new empirical studies in a way that highlights the contributions of the humanities and the sciences. (shrink)

This paper deals with Care of the Self under globalization. The first part refers to Johann P. Arnason’s interpretation of Jan Patočka’s work on super-civilization and shows the contradictions facing people in the Modern Era. It suggests that the concept of moderateness is an adequate point of departure for handling the various contradictions of the current epoch. The second part looks at selected aspects of Confucian philosophy in which moderateness, that is, the permanent search for a “middle position” is an (...) integral part of that philosophical tradition. The critical actualisation of Confucianism as proposed for instance by Heiner Roetz is seen as an appropriate way of developing the dialogical characteristics of Confucian philosophy. In the last part it is stressed that critical theory is of relevance when identifying various forms of suffering and because of its ability to understand and critically evaluate diverse cultural and social contexts. (shrink)

The main aim of this article is to provide a short overview of the research that gradually culminated in the concept of cognitive biology. To a certain extent it can be compared to a prelude: as the Merriam Webster dictionary defines it, “a musical section or movement introducing the theme or chief subject (as of a fugue or suite) or serving as an introduction to an opera or oratorio.” At first glance, this may seem to downplay the importance of the (...) pre-cognitive biology period, but the opposite is true. Some preludes (consider, for example, La Traviata or Carmen) are as rich and beautiful as the acts that follow. We believe this is the case with the story culminating in the birth of cognitive biology, and we present it here in the form of an annotated (and somewhat virtual) interview with its leading actor, Ladislav Kováč. (shrink)

Social consciousness is the most comprehensive historically differentiated and dynamic relatively independent spiritual system. It performs its function both with regard to social being and to the life and consciousness of the individual members of society. As a many-sided, heterogeneous and complex system social consciousness should be analyzed from various points of view. Varied approaches and methods are employed in its study, heterogeneous criteria, close-ups and cross sections are used in investigating its content.

The commentaries by Cacioppo and Cacioppo, Jankowiak, Marazziti, and Aron and Aron admirably illustrate the multifaceted nature of love and the difficulty of bringing together such diverse perspectives. Rising love is still far from being the subject of true experimental study since the experimenter often only observes the consequences thereof, and attempts to reconstitute in hindsight the circumstances of its onset.

Previous research about love, in the social-psychological literature, has focused on the antecedents, or causes, of love. Moreover, within the field of Personal Relationships, love is often regarded as implicitly present, and thus, is not treated directly. Here, we address the possibility of a reversal of this perspective, where love is no longer treated as a dependent variable but as an independent variable. We show that this change is necessary to promote the status of love to that of a reliable (...) object of scientific enquiry. We discuss the differences between scientific and naïve conceptions of love, and the necessity of distinguishingbetween an alleged reality of love and the consequences of the mere idea of love. (shrink)

Reflections on Justice under the Context of Globalization This paper deals with the need to change the way in which we consider justice in connection with globalisation. It analyses injustice in countries with developed capitalism, employing the work of Axel Honneth and Nancy Fraser. The paper highlights the importance of using "critical theory" in relation to developing an acceptable understanding of the term justice, and using "critical theory" in conjunction with Hans Herbert Kögler's "philosophical hermeneutics". In order to adequately investigate (...) contemporary human civilization it is necessary to enrich our knowledge by investigating "civilisational analysis" (Johann P. Arnason). (shrink)

Wexler and Specker Sullivan (2023) note that, “unbridled speculation can imperil the credibility of neuroethics, generate unrealistic expectations amongst different stakeholders, take up time that...

The article Pragmatismand the Importance of Interdisciplinary Teams in Investigating Personality Changes Following DBS.

In order to understand today’s social and political situation in East-Central Europe, one should particularly examine the consequences of post-socialist transformation. The negative and often very painful effects of the social changes that affected Central and Eastern Europe over the past three decades have not been overcome until today. This makes it all the more important to be better prepared philosophically for future social changes. François Jullien offers a number of solutions. In the first part of my paper, taking Jullien’s (...) book The Silent Transformations as a point of departure, I show that many of the problems that still exist in East-Central Europe largely result from placing too much emphasis on the event of the revolution and too little on the transformation experienced by the region’s populations. In the second and third parts, I indicate, pace Jullien, a way towards a moderate, “sober”, but nevertheless creative and productive understanding of the active agent by appealing to the works of Hans-Herbert Kögler and Fabian Heubel. (shrink)

What happens at the end of a clinical trial for an investigational neural implant? It may be surprising to learn how difficult it is to answer this question. While new trials are initiated with increasing regularity, relatively little consensus exists on how best to conduct them, and even less on how to ethically end them. The landscape of recent neural implant trials demonstrates wide variability of what happens to research participants after an neural implant trial ends. Some former research participants (...) continue to receive support for their devices (e.g., battery and component replacements, software updates, etc.). Others, when safe, have their neural implants removed through surgical explantation. Still others continue to live with a deactivated neural implant embedded in their body. In the United States, there are no uniform requirements to provide services, of any kind, after an neural implant study ends, and other nations are similarly facing this challenge. The existence of a post-trial gap in an expanding neural implant research ecosystem invites obvious questions: What is owed to neural implant research participants post-trial, and why has providing it been so difficult to accomplish in practice? To take a step forward on this difficult issue, we assembled one group of stakeholders – researchers funded for neuroethics grants by the National Institutes of Health – to explore possible starting points on one topic: ethical guidance for post-trial care of research participants in neural implant trials. Based on shared concerns discussed in the expert workshop the current paper is a call to action. It reports the key areas of convergence from the meeting and highlights important next steps towards developing much needed guidance. (shrink)

The aim of this study is to evaluate the level of select ethical issues in Visegrad Four (V4) countries (Czech republic, Slovakia, Poland, and Hungary) and quantify the differences in the attitudes of entrepreneurs in the field of business ethics in these countries. Empirical research was conducted in June 2022 in the V4 countries. Data collection was carried out by the renowned external company MNFORCE using "Computer Assisted Web Interviewing" (CAWI Research Method), according to the questionnaire created by the research (...) team. The total number of respondents was 1,398, of which 347 were from the Czech Republic, 322 from Slovakia, 381 from Poland, and 348 from Hungary. Statistical hypotheses were verified using descriptive statistics, chi-square, and Z-scores at a α = 5% significance level. The preliminary results of this study can be evaluated as follows: The ethical level of entrepreneurs in V4 countries is high because the dominant group showed a positive attitude towards the defined issues in the field of business ethics. The attitudes of these entrepreneurs showed that they not only perceived the importance of business ethics, but also implemented and promoted these practices in managerial decision-making. Moreover, they feel good when they behave ethically, which is a significant motivating factor. In this study, it was found that Hungarian SMEs presented the highest level of business ethics. In contrast, the Czech Republic presented the lowest level of perception and enforcement of business ethics. (shrink)

This study examined the effect of the pique technique preceded by a disrupting process. Passersby in the street were asked for money, either for a common amount of change (control) or 37 cents (pique technique). In half of the cases, the requester added a disrupting sentence at the beginning of the request. Results showed that the pique technique alone and the disrupting technique alone increased compliance with the request. Adding a first disrupting sentence to the pique also increased compliance compared (...) with the other three conditions. These results support the theoretical explanation that the initial disrupting sentence associated with the pique could reduce the influence of the refusal script activated by the money request. (shrink)

Objective: To examine changes in patients’ desired control of the deep brain stimulator and perception of global life control throughout DBS.Methods: A consecutive cohort of 52 patients with Parkinson’s disease was recruited to participate in a prospective longitudinal study over three assessment points. Semi-structured interviews assessing participants’ desire for stimulation control and perception of global control were conducted at all three points. Qualitative data were coded using content analysis. Visual analog scales were embedded in the interviews to quantify participants’ perceptions (...) of control over time.Results: Participants reported significant increases in their perception of global control over time and significant declines in their desired control of the stimulation. These changes were unrelated to improvements in motor symptoms. Improvements in global control were negatively correlated with a decline in desired stimulation control. Qualitative data indicate that participants have changed, nuanced levels of desired control over their stimulators. Increased global life control following DBS may be attributed to increased control over PD symptoms, increased ability to engage in valued activities, and increased overall self-regulation, while other domains related to global control remained unaffected by DBS.Conclusions: There are few empirical data documenting patients’ desire for stimulation control throughout neuromodulation and how stimulation control is related to other aspects of control despite the growing application of neuromodulation devices to treat a variety of disorders. Our data highlight distinctions in different types of control and have implications for the development of patient-controlled neurostimulation devices. (shrink)

Deep brain stimulation — a novel surgical procedure — is emerging as a treatment of last resort for people diagnosed with neuropsychiatric disorders such as severe obsessive-compulsive disorder. The US Food and Drug Administration granted a so-called humanitarian device exemption to allow patients to access this intervention, thereby removing the requirement for a clinical trial of the appropriate size and statistical power. Bypassing the rigors of such trials puts patients at risk, limits opportunities for scientific discovery, and gives device manufacturers (...) unique marketing opportunities. We argue that Congress and federal regulators should revisit the humanitarian device exemption to ensure that it is not used to sidestep careful research that can offer valuable data with appropriate patient safeguards. (shrink)

A review of Lubomír Doležel´s Possible Worlds of Fiction and History: The Postmodern Stage (Baltimore: Johns Hopkins University Press, 2010, 171 pp. ISBN 978-0-8018-9463-3).

Není tomu tak dávno, co se ti, kdo vzývali termín "analytická filosofie", v naší zemi jevili jako příslušníci nějaké divné sekty, kteří smysl termínu "filosofie" jakýmsi úchylným způsobem překrucují. Není-li však člověk zrovna Valihrachem, nemůže o tom, co slova znamenají, svévolně rozhodovat; a faktem je, analytická filosofie tvoří podstatnou část toho, co se ve světě pod hlavičkou "filosofie" učí a provozuje. (Já bych řekl, že dokonce většinu, ale statistické údaje samozřejmě k dispozici žádné nemám.) Během posledních zhruba deseti let se (...) ovšem situace podstatně změnila a analytický způsob filosofování se u nás začíná široce etablovat. Existují již překlady celé řady klasických děl (Frege, Russell, Wittgenstein, Popper, ...) i těch novějších (Quine, Davidson, ...), a vznikla i celá řade původních prací. Co dosud scházelo bylo nějaké systematické historické pojednání o tom, jak tento filosofický směr vznikl, jak se vyvíjel a jak dospěl k tomu druhu otázek, který si předsevzal řešit. Tuto mezeru se nyní pokouší zaplnit kniha docenta filosofické fakulty olomoucké univerzity Lubomíra Valenty Problémy analytické filosofie. (shrink)

Nového knížka Filosof T. G. Masaryk (1994) má tři roviny, které se přirozeně neustále stýkají a prolínají: bilancování dosavadní masarykovské literatury s důrazem na rozbor literatury nejnovější, pokus o systematizaci Masarykova díla, postižení jeho vnitřní logiky a vřazení do evropských souvislostí (Brentano, Husserl), a konečně otevírání a řešení otázek, které je možné v užším slova smyslu označit za problémové a aktuální. Nový ukazuje, jak pomáhá Masarykovo myšlení vracet znovu otázku smyslu a řádu našeho usilování a tvoření.