BackgroundResearchers currently are not obligated to share individual research results with participants. This non-disclosure policy has been challenged on the basis of participants’ rights to be aware and in control of their personal medical information. Here, we determined how patients view disclosure of research PET results of brain amyloid and why they believe it is advantageous or disadvantageous to disclose.MethodAs a part of a larger diagnostic trial, we conducted semi-structured interviews with patients with amnestic Mild Cognitive Impairment. Participants had the (...) option to receive their brain amyloid PET scan result. Interviews were conducted before they received their IRR.ResultsA total of 38 aMCI patients wanted to know their IRR. The two most frequently mentioned reasons for choosing IRR disclosure were to better understand their brain health status and to be better able to make informed decisions about future personal arrangements. Emotional risk was mentioned as the primary disadvantage of knowing one’s IRR. On the other hand, non-disclosure was considered to be emotionally difficult also, as patients would be uncertain about their future health condition.ConclusionsMany patients diagnosed clinically with aMCI want to know their brain amyloid test results, even though this knowledge may be disadvantageous to them. Knowing what is going on with their health and the ability to make informed decisions about their future were the two principal advantages mentioned for obtaining their amyloid PET results. Because of the overwhelming consensus of aMCI patients was to disclose their brain amyloid PET scan results, researchers should strongly consider releasing this information to research subjects. (shrink)

Detection of Alzheimer’s disease in an early stage is receiving increasing attention for a number of reasons, such as the failure of drug trials in more advanced disease stages, the demographic evolution, the financial impact of AD, and the approval of amyloid tracers for clinical use. Five focus group interviews with stakeholders were conducted.. The verbatim transcripts were analysed via the Nvivo 11 software. Most stakeholder groups wanted to know their own amyloid PET scan result. However, differences occurred between FGs: (...) two groups wanted to know, whilst in the three other groups FG members opted not to know or were still in doubt about their decision. Stakeholders provided insight into their reasons for wanting to know their amyloid PET scan result, for not wanting to know their result, or why they were in doubt about their decision. Several advantages and disadvantages were mentioned as part of knowing their amyloid PET scan result. Certain considerations were clustered in a grey zone, in between advantage and disadvantage, such as the emotional consequences. Clinicians, researchers, and policymakers ought to be aware of the diversity of reasons for wanting to know their result and how possible benefits and risks can be viewed differently. The current findings are of importance for future early diagnosis and disclosure of results in the research setting. (shrink)

Background: Today, many healthcare or dementia organizations, clinicians, and companies emphasize the importance of detection of Alzheimer’s disease in an early phase. This idea has gained considerable momentum due to the development of biomarkers, the recent FDA and EMA approval of three amyloid tracers, and the failure of a number of recent therapeutic trials conducted in the early dementia phase. On the one hand, an early etiological diagnosis can lead to early and more efficacious intervention. On the other hand, it (...) is questioned how early an etiological diagnosis is beneficial to the patient. Here we consider ethical issues related to the process of biomarker testing and the impact on the diagnostic disclosure to patients with mild cognitive impairment due to prodromal Alzheimer’s disease. Methods: A systematic review of the theoretical bioethics literature was performed by using electronic databases. The review was limited to articles published in English between 2003 and 2016. Results: A total of twenty articles were included in our effort to make an analysis of the ethical challenges. One of the biggest challenges was the uncertainty and the predictive value of the biomarker-based diagnosis where patients can be amyloid positive without full certainty whether or when they will develop symptomatic decline due to Alzheimer’s disease. Another challenge was the tension between the right to know versus the wish not to know, the limited efficacy of currently available treatment options, and the opportunities and consequences after receiving such an early diagnosis. Conclusion: Based on the results and the additional comments in the discussion, several unanswered questions emerged. Therefore, careful consideration of all these ethical issues is required before the disclosure of a biomarker-based diagnosis to the patient with mild cognitive impairment due to Alzheimer’s disease. (shrink)

Introduction -- 1e Intermed consid -- Marx -- Simmel -- Weber -- Lukács -- 2e intermed consid -- Horkheimer -- Adorno -- 3e intermed consid -- Habermas I -- Habermas II -- Habermas III -- Conclusion -- Postscript -- Bibliography.

In this paper, I respond to Pierre Le Morvan’s critique of my thesis that ignorance is lack of true belief rather than absence of knowledge. I argue that the distinction between dispositional and non-dispositional accounts of belief, as I made it in a previous paper, is correct as it stands. Also, I criticize the viability and the importance of Le Morvan’s distinction between propositional and factive ignorance. Finally, I provide two arguments in favor of the thesis that ignorance is lack (...) of true belief rather than absence of knowledge. (shrink)

What's Critical About Critical Realism?: Essays in Reconstructive Social Theory draws together 4 major articles that are situated at the intersection of philosophy and sociology. Preceded by a general presentation of Bhaskar ́s work, critical realism is used to reconstruct the generative structuralism of Pierre Bourdieu, warn about the dangers of biocapitalism, theorize about social movements and explore the hermeneutics of internal conversations. Together, the essays form a logical sequence that starts with a search for a solid conception of social (...) structure through a realist critique of Bourdieu ́s rationalist epistemology, proceeds to an ideology critique of posthumanism through an investigation of Actor-Network Theory, extends critical realism to social movements through an investigation of the constitution of collective subjectivities and engages in a sustained dialogue with Margaret Archer through an attempt to reconnect hermeneutics and pragmatism to critical realism. The result is an ongoing dialogue between British critical realism, French historical epistemology, German critical theory and American pragmatism. As suits a collection of essays in social theory, this book will address a broad audience of sociologists, philosophers, social psychologists and anthropologists who are interested in contemporary social theory at the cutting edge. Academics and advanced students who relate to critical realism and critical theory, epistemology and philosophy of the social sciences, hermeneutics and pragmatism, or anyone else who follows the work of Roy Bhaskar, Pierre Bourdieu, Bruno Latour or Margaret Archer will find a keen interest in some of the theoretical questions the book raises. (shrink)

Can only science deliver genuine knowledge about the world and ourselves? Is science our only guide to what exists? Scientism answers both questions with yes. Scientism is increasingly influential in popular scientific literature and intellectual life in general, but philosophers have hitherto largely ignored it. This collection is one of the first to develop and assess scientism as a serious philosophical position. It features twelve new essays by both proponents and critics of scientism. Before scientism can be evaluated, it needs (...) to be clear what it is. Hence, the collection opens with essays that provide an overview of the many different versions of scientism and their mutual interrelations. Next, several card-carrying proponents of scientism make their case, either by developing and arguing directly for their preferred version of scientism or by responding to objections. Then, the floor is given to critics of scientism. It is examined whether scientism is epistemically vicious, whether scientism presents a plausible general epistemological outlook and whether science has limits. The final four essays zoom out and connect scientism to ongoing debates elsewhere in philosophy. What does scientism mean for religious epistemology? What can science tell us about morality and is a scientistic moral epistemology plausible? How is scientism related to physicalism? And is experimental philosophy really a form of scientism tailored to philosophy? (shrink)

Contemporary capitalism is in effect, if not in intent, Deleuzian. As a network of networks, it is rhizomatic, flexible, chaosmotic, evolving, expanding. In the negativist spirit that characterizes the work of the Frankfurt School, this article shows via an analysis of the goverment of the self, the commodification of culture and the modification of nature, how contemporary capitalism does colonize not only the life-world but also life itself.

ABSTRACTAs a comment on the debate between Dave Elder-Vass and Leigh Price, I propose a dialogue between Bhaskar and Habermas. If we could introduce critical realism into critical theory, we might...

Reading the Communist Manifesto against the contemporary background of massive unemployment, the author argues that Marx's theory of work is no longer adequate to tackle the problem of `workers without work' and suggests that it has to be reformulated in such a way that its normative intuitions and its critical impulses can be maintained. In the first part, he presents a philosophical critique of Marxism that is inspired by Jürgen Habermas and Hannah Arendt. In the second part, he presents a (...) sociological critique of Marxism and argues that the theory of the alienation of work implies a justification of work and the work society. Finally, in the last part, the author presents an ideological critique of Marxism that is inspired by Marcel Mauss' sociology of the gift. Criticising the contractualist assumptions of workfare solutions, he proposes a package solution for a radical decommodification of the labour market by means of a disjunction of income and work. (shrink)

European states, including Belgium, have looked at the construction of Europe through an economie and a political prism. Both dimensions have evolved following parallel paths. In Belgium a large consensus has always existed concerning the economie dimension of the European construction. In this respect Belgiums post-1945 European policies area direct continuation of the interwar efforts to build a West-European economic area, based on a free trade philosophy and a rejection of economic nationalism which always handicapped small trading states such as (...) Belgium. Even before the second world war the Belgian elite thus accepted the principles of economic multilateralism.In the political dimension however a consensus on a federal Europe only emerged at the end of the seventies. Till then, important parts of the Belgian political elite remained sceptical and even hostile to the construction of a supranational Europe, based on a traditional view on political autonomy and independence. The reasons why Belgian views on the political dimension of Europe slowly shifted to a federal objective were partly domestic and partly the result of the growing awareness that a small countries' political interests in the world can be best pursued through supranationality. (shrink)

Pleidooi voor een nieuwe culturele wereldorde die niet uitgaat van het westerse denken in tegenstellingen, maar verschillende denkwijzen en opvattingen erkent en niet uitsluit.

Is our experience of the world 'rich' or 'thin'? In other words, are we aware of unattended sensory stimuli, or are the contents of our consciousness constrained by what we attend to? A recent, ingenious, attempt to address this issue offers us a seemingly unavailable, 'moderate' option; our experience is somewhere between the two. But before we make our minds up about this conclusion, we should see that it resulted from conflating two ways of construing the relevant concepts. I claim (...) that, one way of reading 'rich' vs. 'thin', echoes the psychologists' distinction between 'early' vs. 'late' accounts of selective attention, and I argue that 'perceptual load theory', a recent response to this empirical issue, offers us a satisfying solution to our philosophical problem. Ultimately, we are only aware of what we attend to, so we can conclude that our experience of the world is philosophically 'thin'. Nonetheless, the second way of reading 'rich' vs. 'thin' relates to the range of sensory stimuli that we can be aware of. I claim that this range depends upon the attentional load that our sensory systems are placed under. The 'moderate' position, then, merely marks out one possible degree of sensory awareness on a continuum that runs from 'rich' to 'thin'. (shrink)

This study examines the relationships of servant leadership to organizational commitment, voice behaviors, and antisocial behaviors. Adopting a multifaceted approach to commitment, we hypothesized that servant leadership would be positively related to affective, normative, and perceived sacrifice commitment, but unrelated to few alternatives commitment. We further hypothesized that affective commitment would be positively related to voice behaviors, controlling for the other commitment components, and would mediate a positive relationship between servant leadership and voice behaviors. Similarly, we hypothesized that normative commitment (...) would be negatively related to antisocial behaviors, controlling for the other commitment components, and would mediate a negative relationship between servant leadership and antisocial behaviors. These predictions were tested using matched data from a sample of 181 Canadian customer service employees and their managers. Results largely supported the above predictions. Importantly, affective commitment mediated a positive relationship between servant leadership and voice behaviors. Yet, while servant leadership was positively related to normative commitment and the latter was negatively related to antisocial behaviors, the indirect effect of servant leadership on these behaviors through normative commitment was nonsignificant. Theoretical implications and future research directions are discussed. (shrink)

This paper explores the potential and relevance of an innovative sociological research method known as the Imitation Game for research in health care. Whilst this method and its potential have until recently only been explored within sociology, there are many interesting and promising facets that may render this approach fruitful within the health care field, most notably to questions about the experiential knowledge or ‘expertise’ of chronically ill patients. The Imitation Game can be especially useful because it provides a way (...) to map this experiential knowledge more systematically, without falling in the dual trap of either over-relying on in-depth, but highly specific phenomenological ‘insider’-approaches that are hard to generalize, or, alternatively, problematically reducing the rich life-worlds of patients to a set of indicators in a questionnaire. The main focus of this paper is theoretical and conceptual: explaining the Imitation Game method, discussing its usefulness in the health care domain, and exploring the ways in which the approach can be utilized for chronic illness care. The paper presents both a conceptual and empirical exploration of how the Imitation Game method and its underlying theoretical concepts of ‘contributory expertise’ and ‘interactional expertise’ can be transferred from the sociological realm to the field of health care, what kinds of insights can be gained from the method, which methodological issues it may raise, and what potentially fruitful research routes can be explored. I argue that the Imitation Game can be thought of as a ‘social learning experiment’ that simultaneously enables the participants to learn from each other’s perspectives, allows researchers to explore exciting new possibilities, and also offers the tools to intervene in the practice that is being studied. (shrink)

This book is a volume in the Penn Press Anniversary Collection. To mark its 125th anniversary in 2015, the University of Pennsylvania Press rereleased more than 1,100 titles from Penn Press's distinguished backlist from 1899-1999 that had fallen out of print. Spanning an entire century, the Anniversary Collection offers peer-reviewed scholarship in a wide range of subject areas.

Websites (e.g. intervention websites targeting health risk behaviors) can be effective in achieving their goals if they are used. The actual use, however, is often very low. This study aimed to assess the effect of visual complexity on intention to use websites, by using within-subjects manipulations of visual complexity and cognitive load (1097 trials, N = 93). The results indicate that high visual complexity has a negative effect on intention to use websites ( F (1, 1095) = 14.81, p < (...) .001), but this is fully mediated through attitude towards the website based on the first impression ( F (1, 1094) = 13.41, p < .001). This clearly demonstrates the powerfulness of a first impression before interacting with a website and stresses the need for evidence-based insight into how this first impression is constituted. Keywords: visual complexity; websites; intention to use. (shrink)

Websites can be effective in achieving their goals if they are used. The actual use, however, is often very low. This study aimed to assess the effect of visual complexity on intention to use websites, by using within-subjects manipulations of visual complexity and cognitive load. The results indicate that high visual complexity has a negative effect on intention to use websites = 14.81,p<.001), but this is fully mediated through attitude towards the website based on the first impression = 13.41,p<.001). This (...) clearly demonstrates the powerfulness of a first impression before interacting with a website and stresses the need for evidence-based insight into how this first impression is constituted. Keywords: visual complexity; websites; intention to use. (shrink)

Websites can be effective in achieving their goals if they are used. The actual use, however, is often very low. This study aimed to assess the effect of visual complexity on intention to use websites, by using within-subjects manipulations of visual complexity and cognitive load. The results indicate that high visual complexity has a negative effect on intention to use websites = 14.81, p <.001), but this is fully mediated through attitude towards the website based on the first impression = (...) 13.41, p <.001). This clearly demonstrates the powerfulness of a first impression before interacting with a website and stresses the need for evidence-based insight into how this first impression is constituted. Keywords: visual complexity; websites; intention to use. (shrink)

What does "nature" mean? This general question, central to the social construction of nature, is addressed here by examining one of nature's particulars, Pacific salmon, and by looking at how one group of people, salmon biologists, imbue the fish with meaning. Based upon historical, comparative, and qualitative data, it appears that nature is socially constructed through both cognitive and physical processes. "Salmon"- and indirectly nature - emerges not as a monolithic, timeless, certain entity, but rather as one that is manipulable, (...) fleeting, and the product of a variety of social relations. In particular, public policy and economics appear to have profoundly influenced salmon biologists' cognitive and physical constructions of salmon. (shrink)

This book develops and defends a theory of responsible belief. The author argues that we lack control over our beliefs, but that we can nonetheless influence them. It is because we have intellectual obligations to influence our beliefs that we are responsible for them.

Bioethics, Volume 36, Issue 2, Page 154-161, February 2022.

Philosophical accounts of visual perception have long had to contend with questions of perceptual relativity: visual phenomenology seems to be influenced by factors independent of the objective properties of the external objects we perceive. More recently, a host of such examples has emerged from psychological studies on visual attention. In two prominent accounts of the consequences of this research, Block argues that these effects occur without changes in the way one visually represents the world to be. If true, this would (...) undermine representationalist accounts of the phenomenology of perception, which share a commitment to the claim that phenomenal character supervenes on representational content. Block’s thesis is based on experiments involving non-selective attention, and he draws the metaphysical conclusion that the resources representationalists need to distinguish veridical from illusory perception are nonexistent. The empirical evidence he considers is highly compelling, as is the ‘landscape’ model of attention that appears to underwrite it. However, in discussing these issues, Block also considers a representative example of selective attention, wherein he concedes a point that provides grounds for a plausible representationalist response. I assemble and assess this response, revealing the contradiction at the heart of Block’s thesis, and conclude, that the representationalist should remain unmoved. (shrink)

Reading the Communist Manifesto against the contemporary background of massive unemployment, the author argues that Marx's theory of work is no longer adequate to tackle the problem of `workers without work' and suggests that it has to be reformulated in such a way that its normative intuitions and its critical impulses can be maintained. In the first part, he presents a philosophical critique of Marxism that is inspired by Jürgen Habermas and Hannah Arendt. In the second part, he presents a (...) sociological critique of Marxism and argues that the theory of the alienation of work implies a justification of work and the work society. Finally, in the last part, the author presents an ideological critique of Marxism that is inspired by Marcel Mauss' sociology of the gift. Criticising the contractualist assumptions of workfare solutions, he proposes a package solution for a radical decommodification of the labour market by means of a disjunction of income and work. (shrink)

In their substantive introduction, the editors first revisit two classical sites of controversy which have offered frameworks for theorizing the interplay between materiality and sociality: reification and fetishism. Obviously, these critical vocabularies emerge as crucial sites of perplexity as soon as the ontological boundary between subjects and objects is rendered equally problematic and fluid as the epistemological boundary between the imaginary and the real. A thumbnail sketch of the history of the two discursive traditions provides an elaborate systematic framework for (...) introducing the individual articles. The first axis of debate is generated by conceptual residues of the traditional tug-of-war between idealism and materialism which continues to infiltrate recent redescriptions of the web of sociality/materiality. The concern here is how much autonomy and agency can be granted to material objects in view of their social inscription and symbolic construction, and how far conceptual experiments with the ontological symmetry between humans and nonhumans may take us and/or should be permitted to go. The second axis of debate concerns the fate of critical theory and of ethico-political sensibility in the face of heightened uncertainties about the distinction between what is real, what is constructed, and what is imaginary, and between what may count as a person and what as a thing. (shrink)

In an ironic rejoinder to the postmodern politics of nature, I will adopt an anthropological perspective on culture, which is conspicuous by its absence in the latest wave of science studies, and reformulate the distinction between nature and culture as a reflexive distinction within culture that emerges with modernity. In order to countering the hypertextualism of the constructivists, I will next sketch out a realist theory of nature. Combining the transcendental realism of Roy Bhaskar with the transcendental phenomenology of Edmund (...) Husserl, I will then try to outline the contours of a realist phenomenology of the ontological regions of physical, animal and human nature. Resuming my anthropological considerations on culture, I will finish the article with a progressive account of how the opposition between regional ontologies and regional typologies could be overcome. (shrink)

The article explores the scope and the limits of virtue ethics from the perspective of critical theory and critical realism. Based on new research in moral sociology and anthropology, it ponders how the self-realization of each can be combined with the self-determination of all. The article adopts an action-theoretical perspective on morality and defends the priority of the right over the good. It suggests that in plural and polarized societies, there no longer exists a consensus on any version of the (...) good life. It therefore limits the scope of virtue ethics to personal life and pleads for a minima moralia at the social and political level. (shrink)

The article explores the scope and the limits of virtue ethics from the perspective of critical theory and critical realism. Based on new research in moral sociology and anthro...

a brief history of the study of ignorance. There is a lack of serious investigation into ignorance: apart from the apophatic tradition in the ancient world and the Middle Ages and the more recent fields of agnotology, philosophy of race, and feminist philosophy, ignorance itself has received little philosophical attention. It is then laid out how the field that one would expect to have studied ignorance in detail, namely, epistemology, has failed to do so. The chapter also explores why this (...) could be the case. Subsequently, it is explained what is new about this book and how this fills the important gap in the study of ignorance: it develops and applies an epistemology of ignorance. Finally, it gives a brief overview of the chapters ahead. (shrink)

This research explores the role of emotions in goal-directed behaviour. A model is provided for an emotional goal system whereby appraisals of the consequences of achieving or not achieving a goal are hypothesised to elicit anticipatory emotions; the anticipatory emotions are expected, in turn, to contribute to volitions in the service of goal pursuit (namely, intentions, plans, and the decision to expend energy); goal-directed behaviours next arise in response to volitions and lead to goal attainment; and the latter then functions (...) as the basis for a new set of appraisals and accompanying goaloutcome emotions. The model was tested in a longitudinal study of the responses of 406 adults (243 women, 163 men) in The Netherlands. The context for the study was the regulation of one's bodyweight via exercising and dieting. (shrink)

The relation between role overload and work performance remains insufficiently understood. Drawing upon conservation of resources theory, we expected role overload to negatively relate to performance through psychological strain and this relation to be buffered by leader–member exchange. Study 1 examined depression as a severe type of strain that mediates between role overload and in-role performance, job dedication, and voice behavior. Study 2 used generic, perceived strain as a mediator between role overload and in-role performance and reward recommendations. Both studies (...) tested LMX’s buffering effect, controlling for role ambiguity and conflict. A supplementary panel study assessed the temporal relationship between role overload and strain. Role overload triggered psychological strain, which undermined performance, and LMX acted as a buffer on role overload, but not on role ambiguity or role conflict. We discuss the implications of these findings for theory and practice. (shrink)

Any plausible ethics of belief must respect that normal agents are doxastically blameworthy for their beliefs in a range of non-exotic cases. In this paper, we argue, first, that together with independently motivated principles this constraint leads us to reject occurrentism as a general theory of belief. Second, we must acknowledge not only dormant beliefs, but tacit beliefs as well. Third, a plausible ethics of belief leads us to acknowledge that a difference in propositional content cannot in all contexts count (...) as a criterion for belief individuation. In some contexts, we need to individuate beliefs in a different manner, namely in such a way that they have at least part of their causal history essentially. (shrink)

It has been theoretically proposed that employees’ perceptions of their supervisor social power in the organization entail a potential to influence their beliefs, attitudes, and behaviors. However, no study has investigated such potential. This lack of research stems from the absence of a common understanding around the meaning of perceived supervisor social power and the absence of any validated measure. Therefore, the purpose of this article is to establish PSSP definition and to validate a five-item scale to measure this construct. (...) Three studies encompassing four independent samples of employees from three different countries and three different languages were conducted to assess the validity of PSSP. Results showed that responses to the PSSP scale presented excellent psychometric properties. Furthermore, the structure of the proposed five-item measure of PSSP was found to be invariant across four samples. Finally, PSSP nomological validity was assessed. Study 1 and Study 2 showed that PSSP was positively related to affective organizational commitment. All three studies showed that PSSP acted as a positive moderator of the relation between affective commitment to the supervisor and affective organizational commitment. Together, these studies support the psychometric soundness of the PSSP scale and presented the first evidence of its potential to influence followers. Implications of these findings for future research on supervisor social power are discussed. (shrink)