In this two-part essay, we distinguish several senses in which general relativity has been regarded as “locally special relativistic.” Here, in Part 1, we focus on senses in which a relativistic spacetime has been said to be “locally (approximately) Minkowskian.” After critiquing several proposals in the literature, we present a result capturing a substantive sense in which every relativistic spacetime is locally approximately Minkowskian. We then show that Minkowski spacetime is not distinguished in this result: every relativistic spacetime is locally (...) approximately every other spacetime in the same sense. In Part 2, we will consider “locally specially relativistic” matter theories. (shrink)

In this two-part essay, we distinguish several senses in which general relativity has been regarded as “locally special relativistic.” In Part 1, we focused on senses in which a relativistic spacetime may be said to be “locally (approximately) Minkowskian.” Here, in Part 2, we consider what it might mean to say that a matter theory is “locally special relativistic.” We isolate and evaluate three criteria in the literature and show that they are incompatible: matter theories satisfying one will generally violate (...) others. We then consider what would happen if any of those criteria failed for a given theory. (shrink)

Traditionally, logic has been the dominant formal method within philosophy. Are logical methods still dominant today, or have the types of formal methods used in philosophy changed in recent times? To address this question, we coded a sample of philosophy papers from the late 2000s and from the late 2010s for the formal methods they used. The results indicate that the proportion of papers using logical methods remained more or less constant over that time period but the proportion of papers (...) using probabilistic methods was approximately three times higher in the late 2010s than it was in the late 2000s. Further analyses explored this change by looking more closely at specific methods, specific levels of technical engagement, and specific subdisciplines within philosophy. These analyses indicate that the increasing proportion of papers using probabilistic methods was pervasive, not confined to particular probabilistic methods, levels of sophistication, or subdisciplines. (shrink)

The role or function of experimental and observational replication within empirical science has implications for how replication should be measured. Broadly, there seems to be consensus that replication’s central goal is to confirm or vouchsafe the reliability of scientific findings. I argue that if this consensus is correct, then most of the measures of replication used in the scientific literature are actually poor indicators of this reliability or confirmation. Only meta-analytic measures of replication align functionally with the goals of replication. (...) I conclude by addressing some objections to meta-analysis. (shrink)

The replication or reproducibility crisis in psychological science has renewed attention to philosophical aspects of its methodology. I provide herein a new, functional account of the role of replication in a scientific discipline: to undercut the underdetermination of scientific hypotheses from data, typically by hypotheses that connect data with phenomena. These include hypotheses that concern sampling error, experimental control, and operationalization. How a scientific hypothesis could be underdetermined in one of these ways depends on a scientific discipline’s epistemic goals, theoretical (...) development, material constraints, institutional context, and their interconnections. I illustrate how these apply to the case of psychological science. I then contrast this “bottom-up” account with “top-down” accounts, which assume that the role of replication in a particular science, such as psychology, must follow from a uniform role that it plays in science generally. Aside from avoiding unaddressed problems with top-down accounts, my bottom-up account also better explains the variability of importance of replication of various types across different scientific disciplines. (shrink)

The stopping rule for a sequential experiment is the rule or procedure for determining when that experiment should end. Accordingly, the stopping rule principle (SRP) states that the evidential relationship between the final data from a sequential experiment and a hypothesis under consideration does not depend on the stopping rule: the same data should yield the same evidence, regardless of which stopping rule was used. I clarify and provide a novel defense of two interpretations of the main argument against the (...) SRP, the foregone conclusion argument. According to the first, the SRP allows for highly confirmationally unreliable experiments, which concept I make precise, to confirm highly. According to the second, it entails the evidential equivalence of experiments differing significantly in their confirmational reliability. I rebut several attempts to deflate or deflect the foregone conclusion argument, drawing connections with replication in science and the likelihood principle. (shrink)

The field of bioethics is calling for a new generation of scholars equipped with the normative, empirical, and practical knowledge and expertise to prioritize equity concerns largely underrepresent...

The concept of emergence is commonly invoked in modern physics but rarely defined. Building on recent influential work by Jeremy Butterfield, I provide precise definitions of emergence concepts as they pertain to properties represented in models, applying them to some basic examples from space-time and thermostatistical physics. The chief formal innovation I employ, similarity structure, consists in a structured set of similarity relations among those models under analysis—and their properties—and is a generalization of topological structure. Although motivated from physics, this (...) similarity-structure-based account of emergence applies to any science that represents its possibilia with models. (shrink)

Both early analytic philosophy and the branch of mathematics now known as topology were gestated and born in the early part of the 20th century. It is not well recognized that there was early interaction between the communities practicing and developing these fields. We trace the history of how topological ideas entered into analytic philosophy through two migrations, an earlier one conceiving of topology geometrically and a later one conceiving of topology algebraically. This allows us to reassess the influence and (...) significance of topological methods for philosophy, including the possible fruitfulness of a third conception of topology as a structure determining similarity. (shrink)

I provide a formally precise account of diachronic emergence of properties as described within scientific theories, extending a recent account of synchronic emergence using similarity structure on the theories’ models. This similarity structure approach to emergent properties unifies the synchronic and diachronic types by revealing that they only differ in how they delineate the domains of application of theories. This allows it to apply also to cases where the synchronic/diachronic distinction is unclear, such as spacetime emergence from theories of quantum (...) gravity. In addition, I discuss two further case studies—finite periodicity in van der Pol oscillators and two-dimensional quasiparticles in the fractional quantum Hall effect—to facilitate comparison of this approach to others in the literature on concepts of emergence applicable to the sciences. My discussion of the fractional quantum Hall effect in particular may be of independent interest to philosophers of physics concerned with its interpretation. (shrink)

This review concerns the notions of physical possibility and necessity as they are informed by contemporary physical theories and the reconstructive explications of past physical theories according to present standards. Its primary goal is twofold: first, to motivate and introduce a range of accessible issues of philosophical relevance around these notions; and second, to provide extensive references to the research literature on them. Although I will have occasion to comment on the direction and shape of this literature, pointing out certain (...) lacunae in argument or scholarly attention, I intend to advance no overriding thesis or point of view, aside from the selection of issues I deem most interesting. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Phenomenology and Modern Behavioral PsychologyLindsay B. Fletcher (bio) and Steven C. Hayes (bio)Keywordsacceptance, contextualism, defusion, relational-frame-theoryPérez-Álvarez and Sass (2008) deserve praise for examining the philosophical roots of clinical psychological science. Modern psychology has moved away from the development of philosophy and theory that is needed to ground scientific investigation within a coherent system. The result is increasingly ill-defined constructs and research programs that each operate within their own divergent (...) paradigm. B.F. Skinner is one of the few modern experimental behavioral psychologists who attempted to build a coherent science of behavior based on observable events with testable hypotheses. Acceptance and Commitment Therapy (ACT; Hayes, Strosahl, and Wilson 1999) and its associated basic science of cognition, Relational Frame Theory (RFT; Hayes, Barnes-Holmes, and Roche 2001), build on Skinner’s work to produce a more progressive science.Psychology and philosophy are different disciplines and how they are approached is defined by the objective. The purpose of philosophy from a scientific point of view is not the same as from a philosophical point of view. It is fine to compare radical behaviorism and phenomenology, but it seems important to ask whether and how this will lead to a more progressive science of behavior.In this commentary, we discuss the philosophy and theory that underlie ACT/RFT and show how they reflect on the relevant points made by the authors regarding the shared features of phenomenology and radical behaviorism. We make two adjustments to the explanation of radical behavioral concepts presented in the current paper to create a more coherent analysis. Finally, we show here how the development of a theory based on applied goals directly informs the methods used in clinical settings.Philosophical AssumptionsThe field of behavior analysis that originated with Skinner has different strands. Some are holistic and pragmatic, whereas others are elementalistic and mechanistic (Hayes, Hayes, and Reese 1988). ACT is based on an a-ontological philosophy termed functional contextualism (Hayes 1993), which views behavior analysis from a holistic and pragmatic perspective. Functional contextualism (AKA radical behaviorism) shares some of the assumptions of phenomenology, as has long been noted (Day 1969). For example, Pérez-Álvarez and Sass (2008) identify a-dualism, or monism, as a common feature. In functional contextualism, the whole is divided into functional units for the purpose of prediction and influence. A three-term contingency (antecedent–behavior–consequence) in behavior analysis is viewed as a [End Page 255] whole event with pragmatically distinguishable aspects, not an assemblage. As the authors point out, this results in a dialectic tension between stimulus control, action, and reinforcer because none are distinct units, and each is defined with reference to the others much as the front of a coin cannot exist without the back. These are not ontological entities, but functional units that are abstracted from the whole for pragmatic purposes. What is “radical” about radical behaviorism is that the philosopher, psychologist, or researcher participates in the event they are observing, and their own acts of scientific observation are identified based on their own functional properties.Behavioral ThinkingIn the service of further developing this philosophical and theoretical foundation and considering it along side phenomenology, we need to examine two aspects of the target article. The first regards the role of the environment in shaping behavior that is central to behavioral and contextual theories. The authors object to behaviorism’s notion of environment and suggest replacing it with the concept of the world, stating that “animals have environment, but man has world.” What is missing is an account of that shift. We believe that modern behavior analysis provides that account.Similarly, the paper argues that “reinforcers are not just things that follow behavior, but also, and above all, values that guide our life.” Again what is missing is an account of the precise behavioral basis for the distinction.In an attempt to do this, the authors incorrectly analyze operant behavior as future oriented, even appealing to final causality. In the three-term contingency, the discriminative stimulus sets the occasion for reinforcement of a particular behavior. The behavior of interest has been reinforced in similar contexts in the past, which gives... (shrink)

We implement a recent characterization of metaphysical indeterminacy in the context of orthodox quantum theory, developing the syntax and semantics of two propositional logics equipped with determinacy and indeterminacy operators. These logics, which extend a novel semantics for standard quantum logic that accounts for Hilbert spaces with superselection sectors, preserve different desirable features of quantum logic and logics of indeterminacy. In addition to comparing the relative advantages of the two, we also explain how each logic answers Williamson’s challenge to any (...) substantive account of determinacy: For any proposition p, what could the difference between “p” and “it’s determinate that p” ever amount to? (shrink)

Recent work on the hole argument in general relativity by Weatherall has drawn attention to the neglected concept of models’ representational capacities. I argue for several theses about the structure of these capacities, including that they should be understood not as many-to-one relations from models to the world, but in general as many-to-many relations constrained by the models’ isomorphisms. I then compare these ideas with a recent argument by Belot for the claim that some isometries “generate new possibilities” in general (...) relativity. Philosophical orthodoxy, by contrast, denies this. Properly understanding the role of representational capacities, I argue, reveals how Belot’s rejection of orthodoxy does not go far enough, and makes better sense of our practices in theorizing about spacetime. (shrink)

Amalgamating evidence from heterogeneous sources and across levels of inquiry is becoming increasingly important in many pure and applied sciences. This special issue provides a forum for researchers from diverse scientific and philosophical perspectives to discuss evidence amalgamation, its methodologies, its history, its pitfalls, and its potential. We situate the contributions therein within six themes from the broad literature on this subject: the variety-of-evidence thesis, the philosophy of meta-analysis, the role of robustness/sensitivity analysis for evidence amalgamation, its bearing on questions (...) of extrapolation and external validity of experiments, its connection with theory development, and its interface with causal inference, especially regarding causal theories of cancer. (shrink)

Stephen Hawking, among others, has proposed that the topological stability of a property of space-time is a necessary condition for it to be physically significant. What counts as stable, however, depends crucially on the choice of topology. Some physicists have thus suggested that one should find a canonical topology, a single ‘right’ topology for every inquiry. While certain such choices might be initially motivated, some little-discussed examples of Robert Geroch and some propositions of my own show that the main candidates—and (...) each possible choice, to some extent—faces the horns of a no-go result. I suggest that instead of trying to decide what the ‘right’ topology is for all problems, one should let the details of particular types of problems guide the choice of an appropriate topology. (shrink)

Intertheoretic reduction in physics aspires to be both to be explanatory and perfectly general: it endeavors to explain why an older, simpler theory continues to be as successful as it is in terms of a newer, more sophisticated theory, and it aims to relate or otherwise account for as many features of the two theories as possible. Despite often being introduced as straightforward cases of intertheoretic reduction, candidate accounts of the reduction of general relativity to Newtonian gravitation have either been (...) insufficiently general or rigorous, or have not clearly been able to explain the empirical success of Newtonian gravitation. Building on work by Ehlers and others, I propose a different account of the reduction relation that is perfectly general and meets the explanatory demand one would make of it. In doing so, I highlight the role that a topology on the collection of all spacetimes plays in defining the relation, and how the selection of the topology corresponds with broader or narrower classes of observables that one demands be well-approximated in the limit. (shrink)

Can quantum theory provide examples of metaphysical indeterminacy, indeterminacy that obtains in the world itself, independently of how one represents the world in language or thought? We provide a positive answer assuming just one constraint of orthodox quantum theory: the eigenstate-eigenvalue link. Our account adds a modal condition to preclude spurious indeterminacy in the presence of superselection sectors. No other extant account of metaphysical indeterminacy in quantum theory meets these demands.

Fabi and Goldberg raised important considerations regarding both research and funding priorities in the field of bioethics and, in particular, the field’s misalignment with social justice. W...

Although computation and the science of physical systems would appear to be unrelated, there are a number of ways in which computational and physical concepts can be brought together in ways that illuminate both. This volume examines fundamental questions which connect scholars from both disciplines: is the universe a computer? Can a universal computing machine simulate every physical process? What is the source of the computational power of quantum computers? Are computational approaches to solving physical problems and paradoxes always fruitful? (...) Contributors from multiple perspectives reflecting the diversity of thought regarding these interconnections address many of the most important developments and debates within this exciting area of research. Both a reference to the state of the art and a valuable and accessible entry to interdisciplinary work, the volume will interest researchers and students working in physics, computer science, and philosophy of science and mathematics. (shrink)

We offer a framework for organizing the literature regarding the debates revolving around infinite idealizations in science, and a short summary of the contributions to this special issue.

How can inferences from models to the phenomena they represent be justified when those models represent only imperfectly? Pierre Duhem considered just this problem, arguing that inferences from mathematical models of phenomena to real physical applications must also be demonstrated to be approximately correct when the assumptions of the model are only approximately true. Despite being little discussed among philosophers, this challenge was taken up by mathematicians and physicists both contemporaneous with and subsequent to Duhem, yielding a novel and rich (...) mathematical theory of stability with epistemological consequences. (shrink)

The clock hypothesis of relativity theory equates the proper time experienced by a point particle along a timelike curve with the length of that curve as determined by the metric. Is it possible to prove that particular types of clocks satisfy the clock hypothesis, thus genuinely measure proper time, at least approximately? Because most real clocks would be enormously complicated to study in this connection, focusing attention on an idealized light clock is attractive. The present paper extends and generalized partial (...) results along these lines with a theorem showing that, for any timelike curve in any spacetime, there is a light clock that measures the curve’s length as accurately and regularly as one wishes. (shrink)

The replicability crisis refers to the apparent failures to replicate both important and typical positive experimental claims in psychological science and biomedicine, failures which have gained increasing attention in the past decade. In order to provide evidence that there is a replicability crisis in the first place, scientists have developed various measures of replication that help quantify or “count” whether one study replicates another. In this nontechnical essay, I critically examine five types of replication measures used in the landmark article (...) “Estimating the reproducibility of psychological science” (Open Science Collaboration, Science, 349, ac4716, 2015) based on the following techniques: subjective assessment, null hypothesis significance testing, comparing effect sizes, comparing the original effect size with the replication confidence interval, and meta-analysis. The first four, I argue, remain unsatisfactory for a variety of conceptual or formal reasons, even taking into account various improvements. By contrast, at least one version of the meta-analytic measure does not suffer from these problems. It differs from the others in rejecting dichotomous conclusions, the assumption that one study replicates another or not simpliciter. I defend it from other recent criticisms, concluding however that it is not a panacea for all the multifarious problems that the crisis has highlighted. (shrink)

We consider various curious features of general relativity, and relativistic field theory, in two spacetime dimensions. In particular, we discuss: the vanishing of the Einstein tensor; the failure of an initial-value formulation for vacuum spacetimes; the status of singularity theorems; the non-existence of a Newtonian limit; the status of the cosmological constant; and the character of matter fields, including perfect fluids and electromagnetic fields. We conclude with a discussion of what constrains our understanding of physics in different dimensions.

Merely approximate symmetry is mundane enough in physics that one rarely finds any explication of it. Among philosophers it has also received scant attention compared to exact symmetries. Herein I invite further consideration of this concept that is so essential to the practice of physics and interpretation of physical theory. After motivating why it deserves such scrutiny, I propose a minimal definition of approximate symmetry—that is, one that presupposes as little structure on a physical theory to which it is applied (...) as seems needed. Then I apply this definition to three topics: first, accounting for or explaining the symmetries of a theory emeritus in intertheoretic reduction; second, explicating and evaluating the Curie-Post principle; and third, a new account of accidental symmetry. (shrink)

If one is interested in reasoning counterfactually within a physical theory, one cannot adequately use the standard possible world semantics. As developed by Lewis and others, this semantics depends on entertaining possible worlds with miracles, worlds in which laws of nature, as described by physical theory, are violated. Van Fraassen suggested instead to use the models of a theory as worlds, but gave up on determining the needed comparative similarity relation for the semantics objectively. I present a third way, in (...) which this similarity relation is determined from properties of the models contextually relevant to the truth of the counterfactual under evaluation. After illustrating this with a simple example from thermodynamics, I draw some implications for future work, including a renewed possibility for a viable deflationary account of laws of nature. (shrink)

Book reviewed in this article: Coping with Genetic Disorders. By John C. Fletcher. Genetics, Ethics and Parenthood. Edited by Karen Lebacqz. Screening and Counseling for Genetic Conditions: The Ethical, Social, and Legal Implications of Genetic Screening, Counseling, and Education Programs. A report of the President's Commission for the Study of Ethical Problems in Medicine and Biomedical and Behavioral Research.

This article reflects on the author's modest experience as an expert witness in two trials: Osheroff vs. Greenspan (1983), and In the Matter of Baby K (1994). Bioethicists' expertise as scholar-teachers and consultants on particular issues merits qualification by judges as expert witnesses. The article argues that a different kind of expertise – strong moral advocacy – is required to be an effective expert witness. The major lessons of expert witnessing for the author concern the demands and strains on the (...) bioethicist's role as scholar, teacher, and consultant. The Baby K case is analyzed in some detail, due to its importance for bioethics, ethics consultation, and the testimony of bioethicists on either side of the case. Rules of thumb are offered to guide decisions as to choices regarding expert witnessing, as well as a discussion of the interaction of law and bioethics. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Clinical Bioethics at NIH:History and A New VisionJohn C. Fletcher (bio)On July 3, 1995, Dr. John I. Gallin, Director of the Magnuson Clinical Center of the National Institutes of Health (NIH), convened a one-day "Conference on the Future of Clinical Bioethics at the National Institutes of Health Intramural Program." Conferees included NIH officials and a panel of consultants from bioethics programs around the nation.1 The subject was the future (...) of NIH's intramural bioethics program and specifically a vision of a new multi-component program, presented by Dr. Gallin, the first speaker. Dr. Harold Varmus, Director of NIH, was there to assure his support for Dr. Gallin's vision. This author, honored to be second speaker, was invited to sketch a brief history of bioethics at NIH. The present article reviews some of this history and then reports on Dr. Gallin's proposal, points of consensus among speakers and conferees, and the search for a Chief of the Clinical Bioethics Program.History of Bioethics at NIHIt is often said that NIH is a well-kept secret as the nation's leading biomedical research facility. Also, few people know that NIH has a long history in bioethics. Some key events in that history are shown in Figure 1, beginning with two that occurred prior to the birth of bioethics. NIH made an early policy response to protect human subjects of research and to find acceptable limits for scientific freedom. The Clinical Center (CC), a 550-bed research hospital, opened in 1953. A subcommittee of the Medical Board, the Clinical Research Committee (CRC), was formed for prior group review of all studies with normal volunteers. The traditional practice was for researchers themselves to decide when studies would begin, which subjects to recruit, and whether informed consent would be sought. The CRC intervention bit into this tradition. In addition, patient studies that posed significant risks or departed widely from medical practice were reviewed by referral from the Clinical Directors of the various Institutes. Was this CRC an early institutional review [End Page 355] board (IRB)? As a guest researcher, I was permitted to observe the CRCs meetings between 1966 and 1969. It functioned much like an IRB but had no community or non-scientist members. Other IRB-like review groups undoubtedly existed prior to the CRC. Robert Levine (personal communication, September 7, 1995) recalls that Beth Israel Hospital in Boston had one in 1938. Historical research is clearly needed on the earliest forms of research review.Table 1. Bioethics at NIHEventYearClinical Research Committee1953Surgeon-General's PPO #1291966NIGMS funds Hastings Genetics Group1973OPRR's Mission1974NLM's grant to KennedyInstitute for Bibliography of Bioethics1974Recombinant DNA Advisory Committee1974STEP Series Bioethics Speakers1975Pre-IRBs at the CC1975-76Assistant for Bioethics to Director, CC1977RAC-Human Gene Therapy Subcommittee1983Lipsett Proposal (ICD)1983Liaison Group, CC1983Bioethics Program, CC1985Durable Power of Attorney for Researchwith Incapacitated Subjects1985-86NLM funds National Reference Centerfor Bioethics Literature1985National Institute for Nursing Research1986Bioethics Post-Doctoral Fellows Program1989ELSI Program1989Bioethicists on CC-IRBs1989CC-Ethics Committee1990Office of Human Subjects Research1992 [End Page 356]Between 1963 and 1967, the media exposed instances of ethically troubling research, and Beecher (1966) and Pappworth (1967) published sharp criticisms of the weak state of research ethics. In 1966, Surgeon-General William Stewart and NIH Director James Shannon issued a policy requiring local group review of all research involving human subjects before making an application for NIH peer review (Surgeon General 1966). The policy was the first in any nation to mandate ethics committees for clinical research. However, it did not apply to the NIH intramural program until Congress passed the National Research Act in 1974 (Public Law 93-348; 202, 88 Stat. 342, 1974). This lag permitted NIH intramural investigators the luxury of feeling above the norms imposed on ordinary mortals and guaranteed more resistance to the inevitable change to come. Resistance to change marked the intramural program from the mid-1960s to the mid-1970s... (shrink)

Recently, Horsman et al. have proposed a new framework, Abstraction/Representation theory, for understanding and evaluating claims about unconventional or non-standard computation. Among its attractive features, the theory in particular implies a novel account of what is means to be a computer. After expounding on this account, I compare it with other accounts of concrete computation, finding that it does not quite fit in the standard categorization: while it is most similar to some semantic accounts, it is not itself a semantic (...) account. Then I evaluate it according to the six desiderata for accounts of concrete computation proposed by Piccinini. Finding that it does not clearly satisfy some of them, I propose a modification, which I call Agential AR theory, that does, yielding an account that could be a serious competitor to other leading account of concrete computation. (shrink)

Hospital ethics committees have become widespread over the last 25 years, stimulated by the Quinlan decision of the New Jersey Supreme Court, the report of a President's Commission, and most recently by the Joint Commission on Accreditation of Health Care Organizations , which now man dates that each hospital seeking accreditation have a functioning process for the consideration of ethical issues in patient care. Laws and regulations in several states require that hospitals establish ethics committees, and some states stipulate that (...) certain types of cases and disputes be taken to such committees. At least one state grants legal immunity to those who implement recommendations of an ethics committee. (shrink)

In this note, I apply Norton’s (Philos Sci 79(2):207–232, 2012) distinction between idealizations and approximations to argue that the epistemic and inferential advantages often taken to accrue to minimal models (Batterman in Br J Philos Sci 53:21–38, 2002) could apply equally to approximations, including “infinite” ones for which there is no consistent model. This shows that the strategy of capturing essential features through minimality extends beyond models, even though the techniques for justifying this extended strategy remain similar. As an application (...) I consider the justification and advantages of the approximation of a inertial reference frame in Norton’s dome scenario (Philos Sci 75(5):786–798, 2008), thereby answering a question raised by Laraudogoitia (Synthese 190(14):2925–2941, 2013). (shrink)

Moral and social arguments weigh heavily against performing medical procedures solely for purposes of sex selection. The medical profession has a responsibility to abandon its posture of ethical neutrality and take a firm stand now against sex selection.

As the potential for the first human trials of somatic cell gene therapy nears, two ethical issues are examined: (1) problems of moral choice for members of institutional review boards who consider the first protocols, for parents, and for the clinical researchers, and the special protections that may be required for the infants and children to be involved, and (2) ethical objections to somatic cell therapy made by those concerned about a putative inevitable progression of genetic knowledge from therapy to (...) mass genetic engineering in human reproduction. The author's viewpoint is that a consensus exists on the required moral approach to somatic cell therapy, but that no moral approach yet exists for experiments beyond this level, especially in the germline cells of human beings. Keywords: gene therapy, somatic cells, germ cells, institutional review boards, genetic engineering CiteULike Connotea Del.icio.us What's this? (shrink)