Throughout the sixteenth century, learned physicians across Europe performed a diverse array of “trials” of phenomena and published reports about them. This essay traces the phrase “periculum facere” (“to make a trial”) and related terms through natural history investigations, drug testing, chymical analysis, and anatomical discoveries. Physicians used ancient precedents, their learned expertise, and pedagogical authority to anchor the epistemic status of their trials and incorporated the historical narratives of their trial-making within arguments to factual and causal knowledge, even philosophical (...) scientia. Developed from engagement with things, ancient texts, other healers, and students, this lively tradition of contrived, first-person empirical trials flourished in some academic institutions, especially the University of Padua. The frequency and visibility of sixteenth-century medical trials, especially in the education of hundreds of students annually, is essential evidence for understanding how experimentation came to be widespread in early modern Europe. (shrink)

R J W Evans: Political Chronology; IntroductionJan Rychlík: Czech-Slovak Relations in Czechoslovakia, 1918-39Eagle Glassheim: Ambivalent Capitalists: The Roots of Fascist Ideology among Bohemian Nobles, 1880-1938Melissa Feinberg: The New 'Woman Question': Gender, Nation, and Citizenship in the First Czechoslovak RepublicRobert B. Pynsent: The Literary Representation of the Czechoslovak 'Legions' in RussiaCatherine Albrecht: Economic Nationalism in the Sudetenland, 1918-38R.J.W. Evans: Hungarians, Czechs and Slovaks: Some Mutual Perceptions, 1900-50Mark Cornwall: 'A Leap into Ice-Cold Water': the Manoeuvres of the Henlein Movement in Czechoslovakia, 1933-8Vít (...) Smetana: Old Wine in New Bottles? British Policy towards Czechoslovakia, 1938-9 and 1947-8Tatjana Tönsmeyer: The German Advisers in Slovakia, 1939-45: Conflict or Co-Operation?Mark Dimond: The Sokol and Czech Nationalism, 1918-48Jiri Kocian: The Czechs versus the Slovaks: Bilateral Relations, 1944-8Zdenk Radvanovský: The Transfer of Czechoslovakia's Germans and its Impact in the Border Region after the Second World WarKeith Robbins: Britain and Munich Reconsidered: A Personal Historical Journey. (shrink)

The use of aggregated quality of life estimatesin the formation of public policy and practiceguidelines raises concerns about the moralrelevance of variability in values inpreferences for health care. This variabilitymay reflect unique and deeply held beliefs thatmay be lost when averaged with the preferencesof other individuals. Feminist moral theorieswhich argue for attention to context andparticularity underline the importance ofascertaining the extent to which differences inpreferences for health states revealinformation which is morally relevant toclinicians and policymakers. To facilitatethese considerations, we present (...) an empiricalstudy of preferences for the timing andoccurrence of health states associated withhormone replacement therapy (HRT). Sixteenwomen between the ages of 45 and 55 wereenrolled in this pilot study. Theirpreferences regarding five health statesassociated with HRT (menopausal symptoms, sideeffects of HRT, breast cancer, myocardialinfarction, and osteoporosis) were assessed inquantitative terms known as utilities. Twostandard methods, the visual analog scale (VAS) and the standard gamble (SG), were used toassess utility and time preference (calculatedas a discount rate). The wide variability ofresponses underlines the importance oftailoring health care to individual women'spreferences. Policy guidelines whichincorporate utility analysis must recognize thenormative limitations of aggregatedpreferences, and the moral relevance ofindividual conceptions of health. (shrink)

In the past two to three decades health behavior scientists have increasingly emphasized affect-related concepts (including, but not limited to emotion) in their attempts to understand and facilitate change in important health behaviors, such as smoking, eating, physical activity, substance abuse, and sex. This article provides a narrative review of this burgeoning literature, including relevant theory and research on affective response (e.g., hedonic response to eating and drug use), incidental affect (e.g., work-related stress as a determinant of alcohol use), affect (...) processing (e.g., anticipated regret for illicit sex or skipping an exercise session), and affectively charged motivation (e.g., cigarette craving). An integrative dual-processing framework is presented that suggests pathways through which affect-related concepts may interrelate to influence health behavior. (shrink)

In this paper, planning models developed in artificial intelligence are applied to the kind of planning that must be carried out by participants in a conversation. A planning mechanism is defined, and a short fragment of a free‐flowing videotaped conversation is described. The bulk of the paper is then devoted to an attempt to understand the conversation in terms of the planning mechanism. This microanalysis suggests ways in which the planning mechanism must be augmented, and reveals several important conversational phenomena (...) that deserve further investigation. (shrink)

Daw-Nay N. R. Evans - Nietzsche and Rée: A Star Friendship - Journal of the History of Philosophy 44:4 Journal of the History of Philosophy 44.4 672-673 Muse Search Journals This Journal Contents Reviewed by Daw-Nay N. R. Evans, Jr. DePaul University Robin Small. Nietzsche and Rée: A Star Friendship. Oxford: Clarendon Press, 2005. Pp. xxiv + 247. Cloth, $45.00. Nietzsche attracts a wide range of scholarly enthusiasts. There are those who take Nietzsche seriously as a philosopher and study his (...) works for their own sake, while others seek to mine his works for philosophical gold to determine what he might have to offer their particular area of specialization . On the other hand, there are those who seek to sensationalize Nietzsche by making him.. (shrink)

General preface -- Preface to the second edition -- What is philosophy of religion? -- Philosophy of religion and other disciplines -- Philosophy of religion and philosophy -- Can thinking about religion be neutral? -- Fideism -- Neutralism -- Critical dialogue -- The theistic God : the project of natural theology -- Concepts of God -- The theistic concept of God -- A case study : divine foreknowledge and human freedom -- The problem of religious language -- Natural theology -- (...) Proofs of God's existence -- Classical arguments for God's existence -- Ontological arguments -- Cosmological arguments -- Teleological arguments -- Moral arguments -- Conclusions: The value of theistic argument -- Religious experience -- Types of religious experience -- Models for understanding experience -- Experience of God as direct and mediated -- Are religious experiences veridical? -- Checking experiential claims -- Special acts of God : revelation and miracles -- Special acts -- Theories of revelation -- Is the traditional view defensible? -- What is a miracle? -- Is it reasonable to believe in miracles? -- Can a revelation have special authority? -- Religion, modernity, and science -- Modernity and religious belief -- Naturalism -- Do the natural sciences undermine religious belief? -- Objections from the social sciences -- Religious uses of modern atheism -- The problem of evil -- Types of evil, versions of the problem, and types of response -- The logical form of the problem -- The evidential form of the problem -- Horrendous evils and the problem of hell -- Divine hiddenness -- Faith(s) and reason -- Faith : subjectivity in religious arguments -- The evidentialist challenge to religious belief -- Reformed epistemology -- The place of subjectivity in forming beliefs -- Interpretive judgments and the nature of a cumulative case -- Can faith be certain? -- Faith and doubt : can religious faith be tested? -- What is faith? -- Could one religion be true? (shrink)

This paper forms an introduction to this issue, the contents of which arose directly or indirectly from a conference in May 2001 on Corruption of scientific integrity? — The commercialisation of academic science. The introduction, in recent decades, of business culture and values into universities and research institutions is incompatible with the openness which scientific and all academic pursuit traditionally require. It has given rise to a web of problems over intellectual property and conflict of interest which has even led (...) to corporate sponsors’ suppressing unfavourable results of clinical trials, to the detriment of patients’ health. Although there are those who see the norms of science developing to recognise the importance of instrumental science aiming at specific goals and of knowledge judged by its value in a context of application, none justifies the covert manipulation of results by vested interest.Public awareness of these problems is growing and creating a climate of opinion where they may be addressed. We suggest a way forward by the introduction of nationally and internationally-accepted guidelines for industrial collaboration which contain proper protections of the core purposes of universities and of the independence of their research. Some codes suggested for this purpose are discussed. We note that some universities are moving to adopt such codes of conduct, but argue the need for strong support from the government through its funding bodies. (shrink)

Despite increasing scientific interest in self-generated thought-mental content largely independent of the immediate environment-there has yet to be any comprehensive synthesis of the subjective experience and neural correlates of affect in these forms of thinking. Here, we aim to develop an integrated affective neuroscience encompassing many forms of self-generated thought-normal and pathological, moderate and excessive, in waking and in sleep. In synthesizing existing literature on this topic, we reveal consistent findings pertaining to the prevalence, valence, and variability of emotion in (...) self-generated thought, and highlight how these factors might interact with self-generated thought to influence general well-being. We integrate these psychological findings with recent neuroimaging research, bringing attention to the neural correlates of affect in self-generated thought. We show that affect in self-generated thought is prevalent, positively biased, highly variable (both within and across individuals), and consistently recruits many brain areas implicated in emotional processing, including the orbitofrontal cortex, amygdala, insula, and medial prefrontal cortex. Many factors modulate these typical psychological and neural patterns, however; the emerging affective neuroscience of self-generated thought must endeavor to link brain function and subjective experience in both everyday self-generated thought as well as its dysfunctions in mental illness. (shrink)

`For I do not seek to understand so that I may believe; but I believe so that I may understand. For I believe this also, that unless I believe, I shall not understand.' Does God exist? Can we know anything about God's nature? Have we any reason to think that the Christian religion is true? What is truth, anyway? Do human beings have freedom of choice? Can they have such freedom in a world created by God? These questions, and others, (...) were ones which Anselm of Canterbury took very seriously. He was utterly convinced of the truth of the Christian religion, but he was also determined to try to make sense of his Christian faith. Recognizing that the Christian God is incomprehensible, he also believed that Christianity is not simply something to be swallowed with mouth open and eyes shut. For Anselm, the doctrines of Christianity are an invitation to question, to think, and to learn. Anselm is studied today because his rigour of thought and clarity of writing place him among the greatest of theologians and philosophers. This translation provides readers with their first opportunity to read all of his most important works within the covers of a single volume. ABOUT THE SERIES: For over 100 years Oxford World's Classics has made available the widest range of literature from around the globe. Each affordable volume reflects Oxford's commitment to scholarship, providing the most accurate text plus a wealth of other valuable features, including expert introductions by leading authorities, helpful notes to clarify the text, up-to-date bibliographies for further study, and much more. (shrink)

In this paper, we highlight some problems for accounts of disability and enhancement that have not been sufficiently addressed in the literature. The reason, we contend, is that contemporary debates that seek to define, characterise or explain the normative valence of disability and enhancement do not pay sufficient attention to a wide range of cases, and the transition between one state and another. In section one, we provide seven cases that might count as disability or enhancement. We explain why each (...) case might count, and on what basis, and why it is been neglected. Each case is explained as a transition in what we call capacity space. We then argue that no definition of disability or enhancement addresses all of these cases, except for strict welfarist accounts of disability that do not rely on a depiction of any particular capacity. We argue further, however, that this is a serious deficiency of welfarist conceptions of disability. We then address objections to our account. (shrink)

Book reviewed in this article: The Journey of Life: A Cultural History of Aging in America. by Thomas R. Cole.