Open Innovation and Sustainability-Oriented Innovation are undoubtedly two of the most debated topics of the last decades, gaining the interest of policymakers, practitioners, and scholars all over the world. Even if they have been usually described as two independent research fields, there are some emblematic examples presenting interplay and synergy between these topics, represented either by the hybrid perspectives of Open Sustainable Innovation, that is, the Open Innovation approach acting as an enabler of Sustainability-Oriented Innovation, and Sustainable Open Innovation, which (...) instead analyzes how firms developing Sustainability-Oriented Innovation also adopt the Open Innovation approach. On the basis of these two perspectives and through a systematic literature review, this paper investigates the relationships between the Open Innovation and Sustainability-Oriented Innovation approaches and frames these relationships by developing an innovative framework, which highlights the main aspects characterizing the hybrid perspectives of Open Sustainable Innovation and Sustainable Open Innovation. The proposed framework highlights the Open Innovation practices and strategies enabling Sustainability-Oriented Innovation, as well as the contextual factors enabling both practices and strategies for Sustainability-Oriented Innovation. In addition, it shows how firms developing Sustainability-Oriented Innovation have a similar orientation toward the adoption of the Open Innovation approach both in terms of how they engage stakeholders, and the innovation capabilities they develop. Finally, a research agenda identifying the central issues and the key research gaps is offered for further development in future studies. (shrink)

The use of transcranial Electrical Stimulation in the modulation of cognitive brain functions to improve neuropsychiatric conditions has extensively increased over the decades. tES techniques have also raised new challenges associated with study design, stimulation protocol, functional specificity, and dose-response relationship. In this paper, we addressed challenges through the emerging methodology to investigate the dose-response relationship of High Definition-transcranial Direct Current Stimulation, identifying the role of negative valence in tinnitus perception. In light of the neurofunctional testable framework and tES application, (...) hypotheses were formulated to measure clinical and surrogate endpoints. We posited that conscious pairing adequately pleasant stimuli with tinnitus perception results in correction of the loudness misperception and would be reinforced by concurrent active HD-tDCS on the left Dorsolateral Prefrontal Cortex. The dose-response relationship between HD-tDCS specificity and the loudness perception is also modeled. We conducted a double-blind, randomized crossover pilot study with six recruited tinnitus patients. Accrued data was utilized to design a well-controlled adaptive seamless Bayesian dose-response study. The sample size and optimum interims were anticipated for adaptive decision-making about efficacy, safety, and single session dose parameters. Furthermore, preliminary pilot study results were sufficient to show a significant difference within the longitudinally detected self-report tinnitus loudness between before and under positive emotion induction. This study demonstrated a research methodology used to improve emotion regulation in tinnitus patients. In the projected method, positive emotion induction is essential for promoting functional targeting under HD-tDCS anatomical specificity to indicate the efficacy and facilitate the dose-finding process. The continuous updating of prior knowledge about efficacy and dose during the exploratory stage adapts the anticipated dose-response model. Consequently, the effective dose range to make superiority neuromodulation in correcting loudness misperception of tinnitus will be redefined. Highly effective dose adapts the study to a standard randomized trial and transforms it into the confirmatory stage in which active HD-tDCS protocol is compared with a sham trial. Establishing the HD-tDCS intervention protocols relying on this novel method provides reliable evidence for regulatory agencies to approve or reject the efficacy and safety. Furthermore, this paper supports a technical report for designing multimodality data-driven complementary investigations in emotion regulation, including EEG-driven neuro markers, Stroop-driven attention biases, and neuroimaging-driven brain network dynamics. (shrink)

In P v Cheshire West, Lady Hale stated that an act that would deprive an able-bodied or able-minded person of their liberty would do the same to a mentally or physically disabled person. Throughout the judgement, there is no definition of what liberty is, which makes defining an act that would deprive a person of it difficult. Ideas of liberty are described in terms of political liberty within a society, the state of being free from external influence and individual autonomy. (...) This essay explores various philosophical ideas of liberty and what a legitimate constraint of liberty is. It will be argued that defining liberty in terms external influence from other human agents undermines the impact of natural inability on a person’s ability to fulfil their intrinsic desires—a true constraint of liberty is any which prohibits a person from acting in the way they desire. If liberty is not the same for all, it follows that a deprivation of liberty differs between different agents. Although the government must protect personal liberty, it is important to recognise that an act that may deprive an able-bodied or minded person of their liberty, may in fact promote the liberty of a disabled persons. It will be argued that acts that allow a disabled person to act out desires that they ordinarily would not be able to perform, do not deprive them of their liberty. (shrink)

Background: Physical restraint is among the commonly used methods for ensuring patient safety in intensive care units. However, nurses usually experience ethical dilemmas over using physical restraint because they need to weigh patient autonomy against patient safety. Aim: The aim of this study was to explore factors behind ethical dilemmas for critical care nurses over using physical restraint for patients. Design: This is a qualitative study using conventional content analysis approach, as suggested by Graneheim and Lundman, to analyze the data. (...) Methods: Seventeen critical care nurses were purposefully recruited from the four intensive care units in Tehran, Iran. Data were collected through in-depth semi-structured interviews and were concurrently analyzed through conventional content analysis as suggested by Graneheim and Lundman. Ethical consideration: This study was approved by the Ethics Committee of Iran University of Medical Sciences, Tehran, Iran with the code: IR.IUMS.REC.1397.795. Before interviews, participants were provided with explanations about the aim of the study, the confidentiality of the data, their freedom to participate, and the right to withdraw the study, and their free access to the study findings. Finally, their consents were obtained, and interviews were started. Results: Factors behind ethical dilemmas for critical care nurses over using physical restraint were categorized into three main categories, namely the outcomes of using physical restraint, the outcomes of not using physical restraint, and emotional distress for nurses. The outcomes of using physical restraint were categorized into the three subcategories of ensuring patient safety, physical damage to patients, and mental damage to the patient. The outcomes of not using physical restraint fell into two subcategories, namely the risks associated with not using physical restraint and legal problems for nurses. Finally, the two subcategories of the emotional distress for nurses main category were nurses’ negative feelings about restraint use and uncertainty over the decision on physical restraint use. Conclusion: Decision-making for restraint use is often associated with ethical dilemmas, because nurses need to weight the outcomes of its use against the outcomes of not using it and also consider patient safety and autonomy. Health authorities are recommended to develop clear evidence-based guidelines for restraint use and develop and implement educational and counseling programs for nurses on the principles of ethical nursing practice, patient rights, physical restraint guidelines and protocols, and management of emotional, ethical, and legal problems associated with physical restraint use. (shrink)

According to the ideological surround model of research, a more “objective” psychology of religion requires efforts to bring etic social scientific and emic religious perspectives into formal dialog. This study of 245 Iranian university students illustrated how the dialogical validity of widely used etic measures of religion can be assessed by examining an emic religious perspective on psychology. Integrative Self-Knowledge and Self-Control Scales recorded two aspects of the “Perfect Man” as described by the Iranian Muslim philosopher Mortazā Motahharī. Use of (...) these instruments in correlation and multiple regression procedures identified Intrinsic, Extrinsic Personal, Religious Interpretation, Extrovertive Mysticism, Prayer Fulfillment, Universality, Connectedness, and Religiosity Scales as adaptive in their implications for a Muslim psychology of religion. Religious Crisis had maladaptive and Extrinsic Social, Introvertive Mysticism, and Quest Scales had ambiguous implications. These data illustrated how etic forms of understanding can clarify and can be clarified by emic insights. (shrink)

In this chapter, Zahra Meghani provides a brief overview of the regulatory framework for consumer products in the United States, the European Union and Japan, followed by an extended analysis of their regulation of genetically modified food. The regulatory regimes for GM food of the three regions differ substantially, but they are committed to the same model of scientific risk assessment. That paradigm assumes that risk evaluations are not influenced by any normative concerns. This chapter critiques that conception of (...) risk assessment. It is argued that in the interest of presenting to the public an accurate account of their work, the regulatory entities of the US, the EU, and Japan should acknowledge that their risk assessment of GM food involve normative choices. Moreover, they should create open, transparent, democratic processes to include the public in the deliberations and decision-making about the values that should shape the risk evaluation of GM foods at every stage of the risk assessment process. (shrink)

Gendered Morality offers a textual-critical examination of gender in Islamic metaphysics and virtue ethics. Through a close reading of how masculinity and femininity are constructed, the book argues that the historically contingent nature of gender hierarchy, characterized as Islamic and ethical, is at odds with the overarching goal of Islamic ethics as earthly justice. Because the book moves beyond the typical Qur'anic and jurisprudence-based discourses about women's status, it makes a lasting contribution to our understanding of gender in the ethical (...) philosophy of Islam. (shrink)

It is widely supposed that methodological naturalism, understood as a thesis about the methodology of science, is metaphysically neutral, and that this in turn guarantees the value-neutrality of science. In this paper we argue that methodological naturalism is underpinned by certain ontological and epistemological assumptions including evidentialism and the causal closure of the physical, adoption of which necessitates commitment to metaphysical naturalism.

_Al-Isharat wal-Tanbihat_ is one of the most mature and comprehensive philosophical works by Ibn Sina. Grounded in an exploration of logic and happiness, the text illuminates the divine, the human being, and the nature of things through a wide-ranging discussion of topics. The sections of _Physics and Metaphysics_ deal with the nature of bodies and souls as well as existence, creation, and knowledge. Especially important are Ibn Sina's views of God's knowledge of particulars, which generated much controversy in medieval Islamic (...) and Christian philosophical and theological circles and provoked a strong rejection by eleventh-century philosopher al-Ghazali. This book provides the first annotated English translation of _Physics and Metaphysics_ and edits the original Arabic text on which the translation is based. It begins with a detailed analysis of the text, followed by a translation of the three classes or groups of ideas in the Physics and the four in the Metaphysics (On Existence and Its Causes, Creation Ex Nihilo and Immediate Creation, On Ends, on Their Principles, and on the Arrangement [of Existence], and Onion. _The Metaphysics_ closes with a significant discussion of the concepts of providence, good, and evil, which Ibn Sina uses to introduce a theodicy. Researchers, faculty, and students in philosophy, theology, religion, and intellectual history will find in this work a useful and necessary source for understanding Ibn Sina's philosophical thought and, more generally, the medieval Islamic and Christian study of nature, the world beyond, psychology, God, and the concept of evil. (shrink)

This chapter analyzes the ‘hard sell’ of genetically engineered (GE) mosquitoes with gene drives as the solution to mosquito-borne diseases. A defining characteristic of the aggressive sell of the bio-technology is the ‘biologization’ of the significant prevalence of mosquito-borne diseases in certain socio-economically marginalized regions of the global South. Specifically, hard sell narratives either minimize or ignore the structural, systemic factors that are partially responsible for the public health problem that the GE mosquitoes are intended to bio-solve. The biologization of (...) a public health problem that disproportionately affects low-income, marginalized populations in certain global South regions has epistemic, epidemiological, and gendered ethico-political costs. The primary focus of this chapter is two scientific papers by researchers with ties to Target Malaria, a research organization developing GE mosquitoes with gene drives as the solution to malaria in the global South. In the interest of a contextualized analysis of the hard sell of GE mosquitoes with gene drives in those scientific papers, this chapter examines the normative commitments of Target Malaria’s key backer, the Bill and Melinda Gates Foundation, a powerful private organization that currently dominates the global health governance stage. (shrink)

Zahra Thani & Derek Anderson ABSTRACT: Third-order exclusion is a form of epistemic oppression in which the epistemic lifeway of a dominant group disrupts the epistemic agency of members of marginalized groups. In this paper we apply situated perspectives in order to argue that philosophy as a discipline imposes third-order exclusions on members of marginalized ….

Introduction The discussion of “self-knowledge” as a philosophical issue begins with an intuition. This intuition is based on the fact that our knowledge of our mental states or our knowledge in relation to statements like: “I know that I am happy,” is a particular knowledge that is distinct from the rest of our knowledge. It seems that in order to gain knowledge of ourselves, we do not need to go through those processes that we go through in order to gain (...) knowledge about the external world or knowledge of other minds. We feel that we directly know our own mental states. The role of self-knowledge philosophers is to explain this type of particular knowledge. Theories such as the Inner Sense Theory, the Acquaintance Theory, inferentialism, or theories with a rationalist approach are presented in response to this issue. Considering theories such as the Inner Sense Theory and the Acquaintance Theory, we will find that a common aspect of these theories is that self- knowledge has been defined as a product of an internal observation of our mental states. Such an approach is a kind of Empiricism in self-knowledge. The Rationalist approach has been raised against this approach. This approach, by linking self-knowledge with rationality, has opened a new chapter in the discussion of self-knowledge. The foundation of this approach is based on the principle that our situation as a rational agent plays a fundamental role in self-knowledge. Rationalists believed that this ignorance of the fundamental role of rationality in self-knowledge has caused Empiricists to ignore the most important kind of self-knowledge that is associated with rationality. Tyler Burge, Richard Moran, and Matthew Boyle are some of the important philosophers who theorize about this kind of self-knowledge. Goal In this paper, we will first introduce the main components of Rationalist approaches because we want to review the theoretical literature of this approach. Then, we will bring up a summary of the Tyler Burge view, a famous and important philosopher of the rationalist approach. This is an introduction to introduce Moran’s Theory of Transparency which is the focal point of our discussion. We will then refer to one of the most important challenges facing the Transparency Theory and bring up a significant solution that is presented by Matthew Boyle. We will also show that despite the advantages of this solution, there are ambiguities and other challenges. Finally, we will try to set up two proposals as a way to advance Boyle’s solution. Conclusion The perspective of rationalist philosophers about the existence of a kind of self-knowledge in rational creatures seems to be a powerful idea that is difficult to oppose. Tyler Burge presented interesting arguments about this issue. But it is not easy replying to the question of how this kind of self-knowledge occurs. The theory of Transparency and Reflectivism were proposed to respond to this question. Although they have been considered as efficient theories; however, the mentioned problem still remains ambiguous and complex. Transparency denied the introspective self-knowledge, but couldn’t explain how transparent self-knowledge occurs and therefore, it does not provide a complete explanation for self-knowledge. Some vagueness and some important challenges still continue to exist in this theory. Finally, we propose two proposals as a complement to Boyle’s theory. Maybe they could advance this theory. We suggest that we can use the concept of non-conceptual belief and dispositional belief. These debates have the potential for solving some of the challenges of Transparency and Reflectivism. These are profound topics and need great reflection. We know that our proposals are very elementary and crude ideas. But perhaps they can be a way toward developing the Transparency and Reflectivism theories. (shrink)

Empirical studies exploring managerial views of organizational politics (OP) are scarce. Furthermore, the literature is replete with inconsistent results regarding the correlates of OP. In this paper, data collected from 302 managers were used to examine the association between seven background and work experience variables and managerial attitudes regarding the ethics, locus, affect of OP on the organization, and the motives behind political maneuvering in the workplace. The results, however, show that association between managers' background and work experience factors and (...) attitudes regarding OP is weak. The results suggest several promising lines of inquiry for future research. (shrink)

Personal narratives on changing needs of life, relationship of man with himself, understanding and doubts.

ObjectiveTo evaluate the knowledge and performance of surgical residents regarding the person from whom informed consent should be taken for surgery and from whom the consent is taken in practice.Materials and methodsThis study was done in 2013. The population of this study was all residents of urology, surgery, orthopaedic surgery and gynaecology of Tehran and Iran University of Medical Sciences. The study tool was a self-administered questionnaire, containing questions on their knowledge and performance regarding informed consent acquisition from patients with (...) different conditions in terms of age, sex, marital status and their capacity to make treatment decisions.ResultsA total of 213 residents participated in the study. The mean score of the participants’ knowledge was 72.95 out of 100. There was no significant correlation between the residents’ knowledge and performance. Regarding a competent married male patient, 98.2% of the residents knew that the person’s consent was enough, but only 63.6% obtained informed consent only from the patient. These percentages were 69% and 19.7% for a competent married female patient, respectively. For a competent single male patient, 90.9% of the residents were aware that the patient’s consent was enough, while only 40% of the residents obtained informed consent only from the patient. These percentages were 65.3% and 16% for a competent single female patient, respectively.ConclusionDespite the residents’ average knowledge of patient autonomy, this right is not observed for female patients, and their treatment is subject to consent acquisition from other family members. (shrink)

Is the practice of UK patients traveling to India as medical tourists morally justified? This article addresses that question by examining three ethically relevant issues. First, the key factor motivating citizens of the United Kingdom to seek medical treatment in India is identified and analyzed. Second, the life prospects of the majority of the citizens of the two nations are compared to determine whether the United Kingdom is morally warranted in relying on India to meet the medical needs of its (...) citizens. Third, as neoliberal reforms are justified on the grounds that they will help the indigent populations affected by them, the impact of medical tourism-a neoliberal initiative-on India's socially and economically marginalized groups is scrutinized. © 2013, Baywood Publishing Co., Inc. (shrink)

RésuméMullā Ṣadrā explique la connaissance de soi avec la notion de connaissance par la présence, qui fait référence à la présence immédiate du connu avant le connaissant. L'une des composantes énigmatiques de cette connaissance est que le connaissant et le connu sont l'un avec l'autre dans une relation d'unité. Nous pouvons découvrir la motivation de Ṣadrā à évoquer cette idée énigmatique en réfléchissant au point de vue de Sydney Shoemaker sur la connaissance de soi. Nous montrerons que la motivation de (...) Ṣadrā était sa prise de conscience du concept important d'auto-cécité, une notion introduite dans la philosophie contemporaine par Shoemaker. (shrink)

This book provides the first annotated English translation of Physics and Metaphysics and edits the original Arabic text on which the translation is based where it is corrupt or incomprehensible.

A weighted total of 630 pupils aged 1440. Among 1440-year-olds, especially females. Among 3015-year-old Glasgow Asians 86% were so born, indicating that they are the children of migrants. Generational differences in these comparisons cannot be due to positive selection of the migrant generation for height, and are attributed to improved environment, including nutrition and public health measures. This suggests the possibility of corresponding improvements in coronary and diabetic risk.

For the purposes of conservation or suppression of species, gene drive technology has significant potential. Theoretically speaking, with the release of even relatively few animals with gene drive systems in an ecosystem, beneficial or harmful genes could be introduced into the entire wild-type population of that species. Given the profound impact that gene drives could have on species and ecosystems, their use is a highly contentious issue. Communities and groups have differing beliefs about nature and its conservation or preservation, as (...) well as concerns about the ecological safety of the eradication, replacement or enhancement of particular species of animals by means of genetic engineering. For all those reasons, the rigorous regulation of insects and other animals with gene drive systems is crucial. In this paper, we consider the question of whether the United States Food and Drug Administration is prepared to effectively regulate insects and other animals with gene drives. (shrink)

Acknowledgements -- List of illustrations -- Table of transliteration -- Introduction: Shams al-Din Samarqandi: his life and training -- Works and thought -- Science of the cosmos and the soul ('Ilm al-afaq wa al-anfus) -- Manuscripts used in preparing this edition -- Sources -- Persian and Arabic texts [1-287].

This book explores how decolonial epistemologies are concretely translated in thinking and theorizing about cultural and political practices. Chapters draw on Latin American and Caribbean philosophies and concepts of creolization and racialization, Afropean aesthetics, arts and cultural productions, religion, feminisms, education, and architecture.

It is a widespread belief that Husserl’s conception of time obstructs the way to understanding world-time in a heideggerian sense. Unfolding world-time as one of the main topics of the last phases of Husserl’s analyses of time shall refute this criticism. The process of concretization of the transcendental ego also expresses the silent concretization of the world of phenomenology, and these concretizations lead to the topic of world-time. The study assumes that Husserl’s phenomenology undergoes a process of concretization with its (...) peak in the theme of world-time. (shrink)

Few figures have been of such enduring importance as Ibn Sina, also known as Avicenna (980-1037 AD), the great Persian philosopher and physician of the Abassid period. This work is a study of the fourth part of Ibn Sina's late and most comprehensive book al-Isharat wat-Tanbihat, Remarks and Admonitions, a book which Ibn Sine describes as 'the cream of the truth', containing 'the best pieces of wisdom' expressed 'in sensitive words'. The present volume includes an introduction, discussing the nature of (...) the fourth part of al-Isharat and the procedures followed in analyzing and translating it; a lengthy analysis of Ibn Sina's ideas on the three main topics in this part of al-Isharat (the nature of happiness, the stations of the knowers, and the signs manifested by the knowers); and a translation of this part. The work shows that, to Ibn Sina, knowledge of the eternal aspects of the universe, primarily of God, is the highest human objective and the only thing that secures human happiness or heavenly existence. While no permanent knowledge of this kind is possible for a human being on earth, signs of its temporary acquisition are evidenced in many ways, one of which is possession of powers that a person who does not know the secrets of the universe may consider extraordinary. Although the focus of this volume is on the fourth part of al-Isharat, many references are made to some of Ibn Sina's other writings by way of clarifying certain points and placing this part of al-Isharat in the context of Ibn Sina's general philosophy. (shrink)

Background Decision making regarding the treatment of neonates with poor prognoses is difficult for healthcare staff working in the neonatal intensive care unit. This study aimed to investigate the attitudes of physicians and nurses about the value of life and ethical decision making when encountering neonates with poor prognosis in the NICU. Methods This cross-sectional study was conducted in five NICUs of five hospitals in Tehran city, Iran. The attitudes of 144 pediatricians, gynecologists and nurses were assessed using the questionnaire (...) of attitude toward the value of life and agreement on intensive care management based on three hypothetical case scenarios of neonates with poor prognosis. Data were analyzed using descriptive and inferential statistics via the SPSS software. Results The negative agreement on the no initiation of intensive care measures and the discontinuation of resuscitation in neonates with poor prognosis was more than the positive agreement. Also, various factors influenced the participants’ decision making for the provision of care to neonates. Regarding the case scenarios, the participants agreed on the provision of aggressive, conservative, and palliative care with various frequencies. This study confirms the importance of healthcare providers’ perspectives and their impacts on ethical decision making. The participants favored the value or sacredness of life and agreed on the use of all therapeutic measures for saving the lives of neonates with poor prognosis. Conclusion More studies are required to improve our understandings of factors influencing ethical decision making by healthcare providers when encountering neonates with poor prognosis in NICUs. (shrink)

Islamic theory of knowledge and philosophy; papers of a meeting.

We present a hierarchical self-organizing map based system for online recognition of human actions. We have made a first evaluation of our system by training it on two different sets of recorded human actions, one set containing manner actions and one set containing result actions, and then tested it by letting a human performer carry out the actions online in real time in front of the system’s 3D-camera. The system successfully recognized more than 94% of the manner actions and most (...) of the result actions carried out by the human performer. (shrink)

Nearly all fractions within the political, economic, and social spheres gave responses to the recent financial crisis. In broad terms, both left-leaning and right-leaning scholars and commentators presented their explanations for the crisis, with confident agendas defining ‘what is wrong’ and how to deal with it. However, as intellectual history shows us, most of those explanations were no less fascinating precisely because they shared more that they acknowledged. A major divide has been over the role of governments in coordinating markets, (...) or, in the case of Roberts’sThe Logic of Discipline, the role of markets in coordinating governments. In this essay, I offer an overview of Alasdair Roberts’s arguments inThe Logic of Discipline. Gradually, I extend the examined issues beyond the state-market dichotomy, arguing that only in understanding the interactive force of the two can a systemic analysis of capitalism hope to be plausible. (shrink)

The primary responsibility of the US Food and Drug Administration is to protect public health by ensuring the safety of the food supply. To that end, it sometimes conducts risk assessments of novel food products, such as genetically modified food. The FDA describes its regulatory review of GM food as a purely scientific activity, untainted by any normative considerations. This paper provides evidence that the regulatory agency is not justified in making that claim. It is argued that the FDA’s policy (...) stance on GM food is shaped by neoliberal considerations. The agency’s review of a genetically engineered animal, the AquAdvantage salmon, is used as a case study to track the influence of neoliberalism on its regulatory review protocol. After that, an epistemic argument justifying public engagement in the risk assessment of new GM food is outlined. It is because risk evaluations involve normative judgments, in a democracy, layperson representatives of informal epistemic communities that could be affected by a new GM food should have the opportunity to decide the ethical, political or other normative questions that arise during the regulatory review of that entity. (shrink)