My aim in this paper is to investigate what epistemic role, if any, do appeals to representations play in cognitive neuroscience. I suggest that while at present they seem to play something in between a minimal and a substantive explanatory role, there is reason to believe that representations have a substantial contribution to the construction of neuroscientic explanations of cognitive phenomena.

An increasing number of philosophers have promoted the idea that mechanism provides a fruitful framework for thinking about the explanatory contributions of computational approaches in cognitive neuroscience. For instance, Piccinini and Bahar :453–488, 2013) have recently argued that neural computation constitutes a sui generis category of physical computation which can play a genuine explanatory role in the context of investigating neural and cognitive processes. The core of their proposal is to conceive of computational explanations in cognitive neuroscience as a subspecies (...) of mechanistic explanations. This paper identifies several challenges facing their mechanistic account and sketches an alternative way of thinking about the epistemic roles of computational approaches used in the study of brain and cognition. Drawing on examples from both low-level and systems-level computational neuroscience, I argue that at least some computational explanations of neural and cognitive processes are partially independent from mechanistic constraints. (shrink)

One reason for the popularity of Craver’s mutual manipulability account of constitutive relevance is that it seems to make good sense of the experimental practices and constitutive reasoning in the life sciences. Two recent papers propose a theoretical alternative to in light of several important conceptual objections. Their alternative approach, the no de-coupling account, conceives of constitution as a dependence relation that once postulated provides the best explanation of the impossibility of breaking the common cause coupling of a macro-level mechanism (...) and its micro-level components. This entails an abductive view of constitutive inference. Proponents of the NDC or abductive account recognize that their discussion leaves open a big question concerning the practical dimension of the notion of constitutive relevanssssce: Is it possible to faithfully reconstruct constitutional reasoning in science in terms of a failure to de-couple, via interlevel experiments, phenomena from their mechanistic constituents? Focusing on the field of memory and long-term potential research, this article argues that the abductive account provides a more adequate description of interlevel experiments in neuroscience. We also suggest that the account highlights some significant practical recommendations of how to interpret the findings of interlevel experiments. 1Introduction 2Mutual Manipulability and Constitutive Relevance 2.1Constitutive relevance through an interventionist lens 2.2Mutual manipulability: A methodological application 3Trouble for the Mutual Manipulability Account 4The Abductive Account of Constitution 5The Abductive Account: A Methodological Application 5.1Long-term potential and memory experiments 5.2A comparative summary 6Conclusions. (shrink)

The increasing application of network models to interpret biological systems raises a number of important methodological and epistemological questions. What novel insights can network analysis provide in biology? Are network approaches an extension of or in conflict with mechanistic research strategies? When and how can network and mechanistic approaches interact in productive ways? In this paper we address these questions by focusing on how biological networks are represented and analyzed in a diverse class of case studies. Our examples span from (...) the investigation of organizational properties of biological networks using tools from graph theory to the application of dynamical systems theory to understand the behavior of complex biological systems. We show how network approaches support and extend traditional mechanistic strategies but also offer novel strategies for dealing with biological complexity. (shrink)

Philosophical accounts of scientific explanation are broadly divided into ontic and epistemic views. This paper explores the idea that the lexical ambiguity of the verb to explain and its nominalisation supports an ontic conception of explanation (Salmon 1989; Craver 2007). I analyse one argument which challenges this strategy by criticising the claim that explanatory talk is lexically ambiguous (Wright, European Journal of Philosophy of Science 2(3), 375–394, 2012). I propose that the linguistic mechanism of transfer of meaning (Nunberg, Journal of (...) Semantics 12(2), 109–132, 1995) provides a better account of the lexical alternations that figure in the systematic polysemy of explanatory talk, and evaluate the implications of this proposal for the debate between ontic and epistemic conceptions of scientific explanation. (shrink)

Turing patterns are a class of minimal mathematical models that have been used to discover and conceptualize certain abstract features of early biological development. This paper examines a range of these minimal models in order to articulate and elaborate a philosophical analysis of their epistemic uses. It is argued that minimal mathematical models aid in structuring the epistemic practices of biology by providing precise descriptions of the quantitative relations between various features of the complex systems, generating novel predictions that can (...) be compared with experimental data, promoting theory exploration, and acting as constitutive parts of empirically adequate explanations of naturally occurring phenomena, such as biological pattern formation. Focusing on the roles that minimal model explanations play in science motivates the adoption of a broader diachronic view of scientific explanation. (shrink)

Philosophical Perspectives on the Engineering Approach in Biology provides a philosophical examination of what has been called the most powerful metaphor in biology: The machine metaphor. The chapters collected in this volume discuss the idea that living systems can be understood through the lens of engineering methods and machine metaphors from both historical, theoretical, and practical perspectives. In their contributions the authors examine questions about scientific explanation and methodology, the interrelationship between science and engineering, and the impact that the use (...) of engineering metaphors in science may have for bioethics and science communication, such as the worry that its wide application reinforces public misconceptions of the nature of new biotechnology and biological life. The book also contains an introduction that describes the rise of the machine analogy and the many ways in which it plays a central role in fundamental debates about e.g. design, adaptation and reductionism in the philosophy of biology. The book will be useful as a core reading to professionals as well as graduate and undergraduate students in courses of philosophy of science and for life scientists taking courses in philosophy of science and bioethics. (shrink)

The inconsistent relation between word frequency and free recall performance and the non-monotonic relation found between the two cannot all be explained by current theories. We propose a theoretical framework that can explain all extant results. Based on an ecological psychology analysis of the free recall situation in terms of environmental and informational resources available to the participants, we propose that because participants’ cognitive system has been shaped by their native language, free recall performance is best understood as the end (...) result of relational properties that preexist the experimental situation and of the way the words from the experimental list interact with those. In addition to this, we borrow from predictive coding theory the idea that the brain constantly predicts “what is coming next” so that it is mainly prediction errors that will propagate information forward. Our ecological psychology analysis indicates there will be “prediction errors” because the word frequency distribution in an experimental word list is inevitably different from the particular Zipf’s law distribution of the words in the language that shaped participants’ brains. We further propose the particular distributional discrepancies inherent to a given word list will trigger, as a function of the words that are included in the list, their order, and of the words that are absent from the list, a surprisal signal in the brain, something that is isomorphic to the concept of Bayesian surprise. The precise moment when Bayesian surprise is triggered will determine to what word of the list that Bayesian surprise will be associated with, and the word the Bayesian surprise will be associated with will benefit from it and become more memorable as a direct function of the magnitude of the surprisal. Two experiments are presented that show a proxy of Bayesian surprise explains the free recall performance and that no effect of word frequency is found above and beyond the effect of that proxy variable. We then discuss how our view can account for all data extant in the literature on the effect of word frequency on free recall. (shrink)

Razón, poesía, historia.--La cuestión del estoicismo español.--El querer.

In the first half of the 2000s, one project to restore the former Danube floodplain was carried out in Belene, a marginal town on the Bulgarian Danube. The aim of this article is to record the practices that were already in place before the interventions on the Danube, as part of a heterogeneous local knowledge that had an alternative vision to the scientific knowledge of experts involved in the restoration project. The data comes from qualitative interviews with locals and experts (...) implicated in this project, as well as ethnographic observations from the fieldwork I carried out in 2013–2014, 2020 and 2022. The conclusion is that without attempting to replace the scientific knowledge, the locals aim to impose, through their local knowledge, a sort of slow ecology that eases the pace of the restoration of the former Danube floodplains. (shrink)

Dibujar el pensamiento de Seneca es dibujar su figura viva, trazar el esquema de su persona. Seneca es un mediador que para alzarse sobre nosotros necesita de nuestra necesidad, pues solo apoyado en nuestra indigencia tiene sentido. Maria Zambrano lleva a cabo un lucido estudio de la figura y significacion del pensador cordobes y presenta una seleccion de sus escritos.

The main aim of this article is to examine the contrast between humanism and anti-humanism as two different modern paradigms of considering the individual’s relationship with nature. My thesis is that ecology, as an ideological discourse, reshaped the both the democratic and totalitarian perspectives on humanism and anti-humanism by addressing liberties, self-care, and authenticity in terms of normative laws for environment, health, and the idea of naturalness. Reconsidering Luc Ferry’s analysis from The New Ecological Order: Tree, Animal, Human, I will (...) explain how a social-critical theory of modernity might be conceived in the terms of humanism and anti-humanism, represented by different ecological discourses whose main contribution was to add to the modern social contract the value of non-human beings, including animals, plants, and natural objects as subjects of law (in their most democratic versions) or to discount the value of humans (in their totalitarian structures), viewing racism, for example, as a clinical, biopolitical, and hence “ecological” discourse. I will argue that this condition is a cultural symptom of the anti-natural attitude of the modern individual. (shrink)

If a certain primacy of possibility (existential possibility or egological potentiality) can be acknowledged in both Husserl and Heidegger, the French reception of phenomenology deploys one of its important means of accomplishing its radicalization gesture by putting forward the experiences of the impossible, as the case of Michel Henry and of Jean-Luc Marion shows. Michel Henry elaborates a radicalized phenomenology, which deals with the radical immanence of life, whose passivity and finitude reveal an impossibility that only an infinite, absolute Life (...) can overcome. For Jean-Luc Marion, the givenness of the phenomenon discloses its extreme possibility, that of its saturation, which makes its subjective constitution impossible and paves the way for the phenomenological possibility of divine revelation. Our inquiry attempts to show that both these endeavours can be ultimately regarded as radicalizations of the finitude of the living (or human) being. (shrink)

Parole coupée, bouche bée, yeux grands ouverts, sourcils levés... Plutôt que langagière, l'expression de la surprise serait d'abord le fait du corps. On se propose dans cet ouvrage d'interroger de manière critique, voire de contrebalancer cette tendance habituelle à ranger l'expérience de la surprise du côté du silence et de l'indicible : au lieu de faire signe vers les éventuelles limites du langage et des différentes langues naturelles, la surprise ne fait-elle pas plutôt ressortir la richesse des ressources du langage (...) et la plasticité du fonctionnement des langues? Comment se dit donc la surprise? Dans quelle mesure son expression varie-t-elle d'une langue à l'autre? Le dire de la surprise est-il en lui-même un agir, à son tour producteur d'effets? Ces interrogations nous ont invités à réfléchir tant au lexique de la surprise qu'aux formes d'expression au moyen desquelles la surprise peut être non seulement exprimée mais aussi décrite, racontée, ou bien encore rationalisée, dans la langue courante, dans la logique comme dans la littérature. (shrink)

Spectroscopy is a scientific topic at the interface between Chemistry and Physics, which is taught at high school level in relation with its fundamental applications in Analytical Chemistry. In the first part of the paper, the topic of spectroscopy is analyzed having in mind the well-known Johnstone’s triangle of chemistry education, putting in evidence the way spectroscopy is usually taught at the three levels of chemical knowledge: macroscopic/phenomenological, sub-microscopic/molecular and symbolic ones. Among these three levels, following Johnstone’s recommendations the macroscopic (...) one is the most useful for high school students who learn spectroscopy for the first time. Starting from these premises, in the second part of the paper, we propose a didactic sequence which is inspired by the historical evolution of spectroscopic instruments from the first spectroscopes invented by Gustav Kirchhoff and Robert Bunsen in 1860 to the UV–vis spectrophotometers which became common since the 1960s. The idea behind our research is to analyze the conceptual advancements through the history of spectroscopy and to identify the key episodes/experiments and spectroscopic instruments. For each of them, a didactic activity, typically an experiment, is then proposed underlining the relevant aspects from the chemistry education point of view. The present paper is the occasion to reflect on the potentialities of an historical approach combined with a laboratorial one, and to discuss the role of historical instruments and related technological improvements to teach spectroscopy. (shrink)

Hilary Putnam is one of the world’s leading philosophers. His highly original and often provocative ideas have set the agenda for a variety of debates in philosophy of science, philosophy of mind and philosophy of language. His now famous philosophical thought experiments, such as the ‘Twin earth’ and ‘the brains in the vat’ have become part of the established canon in philosophy and cognitive science. _Reading Putnam_ is an outstanding overview and assessment of Hilary Putnam’s work by a team of (...) international contributors, and includes replies by Putnam himself. Divided into clear sections, it contains chapters on key aspects of Putnam’s large body of writing, including: Scientific realism and the changes that Putnam’s thought has undergone on this topic analyticity and ontology, including the important interconnections between the views of Putnam and Quine Putnam’s arguments concerning externalist views of meaning and reference, questions of conceptual relativity, and his preoccupation with ethics through a denial of the fact–value dichotomy Putnam’s developing views on perception. Offering an excellent survey of Putnam’s work, _Reading Putnam_ is essential for those studying philosophy of mind, philosophy of language, and philosophy of science, as well as for anyone interested in contemporary philosophy. (shrink)

In the literature, the pragmatic dimension of metaphors has been clearly acknowledged. Metaphors are regarded as having different possible uses, especially pursuing persuasion. However, an analysis of the specific conversational purposes that they can be aimed at achieving in a dialogue and their adequacy thereto is still missing. In this chapter, we will address this issue focusing on the classical distinction between the explanatory and persuasive uses of metaphors, which is, however, complex to draw at an analytical level and often (...) blurred and controversial also from a theoretical point of view. Building on the analysis of explanation in different theories and fields of study, we show how it can be conceived as characterized by a cognitive and a pragmatic dimension, where the transference of understanding is used pragmatically for different dialogical goals - such as informing, making a joint decision, and most importantly persuading. In this sense, the cognitive effects of understanding are not incompatible with a persuasive dialogical purpose. This theoretical proposal will be applied to examples drawn from the medical context, to show how a pragmatic approach to explanation can account for the complexity of the cases that can be found in actual dialogical contexts. (shrink)

« Un peu plus de cent vingt ans après l’invention des frères Lumière, la richesse des combinaisons disponibles ou envisageables entre poésie, traduction et film permet de rebattre les cartes de l’histoire qui voudrait que la poésie précède le cinéma et que la traduction soit seconde. Ainsi le poème peut-il traduire (à distance variable) le film en mots et vice versa, le sous-titrage être poésie, la traduction être à l’origine du film-poème, le corps de l’interprète en langue des signes se (...) faire poème et traduction, la poésie de la bande-son se faire traduction d’une situation géopolitique et ainsi de suite. La définition même de ce qu’il faut entendre par « poésie », « traduction » et « cinéma » se trouve enrichie de ces allers et retours et entremêlements. »--. (shrink)

In the context of increased movement across borders, this book examines how key cultural texts and concepts are transferred between nations and languages as well as across different media. The texts examined in this book are considered fundamental to their source culture and can also take on a particular relevance to other cultures. The chapters investigate cultural transfers and differences realised through translation and reflect critically upon the implications of these with regard to matters of cultural identity. The book offers (...) an important contribution to cultural approaches in translation studies, with ramifications across different disciplines, including literary studies, history, philosophy, and gender studies. The chapters offer a range of cultural and methodological frameworks and are written by scholars from a variety of language and cultural backgrounds, Western and Eastern. (shrink)

The transcendental turn of Husserl's phenomenology has challenged philosophers and scholars from the beginning. This volume inquires into the profound meaning of this turn by contrasting its Kantian and its phenomenological versions. Examining controversies surrounding subjectivity, idealism, aesthetics, logic, the foundation of sciences, and practical philosophy, the chapters provide a helpful guide for facing current debates.

Probability as understood today, namely as a quantitative notion expressible by means of a function ranging in the interval between 0–1, took shape in the mid-17th century, and presents both a mathematical and a philosophical aspect. Of these two sides, the second is by far the most controversial, and fuels a heated debate, still ongoing. After a short historical sketch of the birth and developments of probability, its major interpretations are outlined, by referring to the work of their most prominent (...) representatives. The final section addresses the question of whether any of such interpretations can presently be considered predominant, which is answered in the negative. (shrink)

Dal "disegno su sabbia" delle donne australiane alle terrecotte delle donne del Camerun, dai retablos peruviani agli altari vodou degli immigrati haitiani a New York, dalla "Casa del popolo" del regno di Bandjoun alle "vetrinette" italiane degli anni Sessanta, dai malanggan e dai manufatti annodati dell'Oceania alla topologia dei nodi, dai bologan del Mali alla "Potlatch Collection" rimpatriata nei nuovi musei indigeni del Canada, dalle maschere gelede degli Yoruba alla figura ubiqua e mediatica di Mami Wata, i saggi di questo (...) volume evidenziano le valenze operative dell'arte: sia nell'arena sociale e politica contemporanea, cui appartengono anche le "tradizioni", sia nel campo cognitivo e religioso. A lungo confinata ai soli territori esotici delle culture "primitive" e limitata da un'eccessiva dipendenza dalle categorie interpretative occidentali, la riflessione antropologica sull'arte e sull'estetica trova oggi un nuovo respiro teorico, e un nuovo fascino. (shrink)

Our current moral relativism has blurred the distinction between true and false and even between right and wrong by accepting multiple truths and subjective truths as valid evaluations of reality. Serban documents that man, in the process of pursuing his goals, tends to manipulate others. Adapting through deception, particularly in crisis, is part of our animal heritage. Our thought processes, protective of our emotions and self-image, are perfectly adapted for the task of lying.

DNA microarrays are perfectly suited for comparing gene expression in different populations of cells. An important application of microarray techniques is identifying genes which are activated by a particular drug of interest. This process will allow biologists to identify therapies targeted to particular diseases, and, eventually, to gain more knowledge about the biological processes in organisms. Such an application is described in this paper. It is focused on diabetes and obesity, which is a genetically heterogeneous disease, meaning that multiple defective (...) genes are responsible for the diseases. The paper is divided in three parts, each dealing with a different problem addressed to our study. First we validate the data from our microarray experiment. We identified significant systematic sources of variability which are potentially issues for other microarray datasets. Second, we applied multiple hypothesis testing to identify differentially expressed genes. We found a set of genes which appear to change in expression level over time in response to a drug treatment. Third, we tried to address the problem of identification of co-expressed genes using cluster analysis. This last problem is still under discussion. (shrink)

This paper addresses the question of ethnic entrepreneurship in relation to religious identity and multiculturalism in civil society and proposes a spotlight on Turkish entrepreneurs in Romania, as a relevant example of the benefits of increasing cultural diversity and opportunities to learn from different cultures and traditions. It aims at empirically investigating whether the distinct ethnic features of Turkish entrepreneurs, especially their religion, influence their business performance in Romania and their integration in the host country’s civil society. The information for (...) this case study has been collected through in-depth interviews with top representatives of Turkish-Tartar minority associations in Romania and of Turkish Businessman Association (TIAD), and combined with statistical data from various sources. Several characteristics have been considered in our research, with a focus on business performance, religion and civil society. So far ethnic entrepreneurship issue has been approached in Romanian scientific research only indirectly or partially. Our paper singles out this issue and opens the door for further interdisciplinary research and dialogue. (shrink)

Si nous avons placé notre examen du traitement théorique que Michel Henry a réservé à l?intentionnalité sous le signe du fondement qu?il cherche à lui assigner, c?est parce que l?une de nos principales ambitions sera de montrer que la critique que le philosophe français fait de ce leitmotiv de la phénoménologie husserlienne ne doit pas être comprise comme une tentative d?expulsion de l?intentionnalité hors du champ des recherches phénoméno­logiques, mais comme une entreprise de fondation. Dans cette perspective, le point de (...) départ de Michel Henry réside dans une question très simple : l?intentionnalité est-elle susceptible de se fonder elle-même, trouve-t-elle son fondement en elle-même ? Ou sinon, quelle est sa condition de possibilité ? Ainsi, plutôt que de se contenter d?une attitude descriptive à l?égard d?un comportement intentionnel qui serait à chaque fois déjà donné, déjà opérant, il s?agit de soumettre l?intentionnalité à un questionnement de type trans­cendantal, pour la reconduire vers ce « qui la rend ultimement possible » 1 . Le trajet suivi par cette reconduction de l?intentionnalité à son fonde­ment est esquissé par Michel Henry de façon exemplaire dans son article, désormais célèbre, de 1995, « Phénoménologie non intentionnelle : une tâche de la phénoménologie à venir » 2 ; c?est ce texte qui nous donnera la première assise de notre analyse. Toutefois, précisément. (shrink)

Pour comprendre la célèbre formule de Heidgger dans Etre et temps, "plus haut que l'effectivité se tient la possibilité", il fallait mettre en perspective la doctrine de 1927 avec les thèmes qui, chez Husserl puis Heidegger, la préparaient et la rendaient inévitable. Il fallait surtout montrer comment la remise en cause de l'opposition standard entre possibilité et impossibilité (qui définit le concept métaphysique d'étant) fait concevoir un dépassement possible de la métaphysique. C'est ce qui est fait dans cet ouvrage, d'abord (...) suivant Husserl (le monde réduit, entre effectivité et possibilité ; les potentialités de la conscience ; les possibilités de l'expérience), puis suivant Heidegger (la vie facticielle ; l'angoisse et l'existencial ; la possibilité temporelle). A partir de quoi sont abordés de manière systématique et non plus historique les deux points centraux : le dépassement de la métaphysique au profit d'une possibilité événementiale et la phénoménalité de l'impossible et du possible. (shrink)