Transnational politics and labor markets are undermining national industrial relations systems in Europe. This article examines the construction industry, where the internationalization of the labor market has gone especially far. To test hypotheses about di ferences between “national systems,” the authors examine the United Kingdom, Finland, and Germany, alongside European-level policy making. Regardless of overall national institutional framework, employers seek to avoid industrial relations rules, while unions attempt to relocalize labor relations. Both use shop-floor, national, and European power resources. The (...) authors argue that comparative industrial relations should take seriously the connection between action at the national and transnational levels. (shrink)

Whole genome sequencing is quickly becoming more affordable and accessible, with the prospect of personal genome sequencing for under $1,000 now widely said to be in sight. The ethical issues raised by the use of this technology in the research context have received some significant attention, but little has been written on its use in the clinical context, and most of this analysis has been futuristic forecasting. This is problematic, given the speed with which whole genome sequencing technology is likely (...) to be incorporated into clinical care. This paper explores one particular subset of these issues: the implications of adopting this technology in the prenatal context without a good understanding of when and how it is useful. Prenatal whole genome sequencing differs from current prenatal genetic testing practice in a number of ethically relevant ways. Most notably, whole genome sequencing would radically increase the volume and scope of available prenatal genetic data. The wealth of new data could enhance reproductive decision‐making, promoting parents' freedom to make well‐informed reproductive decisions. We argue, however, that there is potential for prenatal whole genome sequencing to alter clinical practice in undesirable ways, especially in the short term. We are concerned that the technology could (1) change the norms and expectations of pregnancy in ways that complicate parental autonomy and informed decision‐making, (2) exacerbate the deleterious role that genetic determinism plays in child rearing, and (3) undermine children's future autonomy by removing the option of not knowing their genetic information without appropriate justification. (shrink)

Our commentary aims to show that the COVID-19 pandemic has amplified existing barriers to healthcare in England for ethnic minority and migrant women. We expose how the pandemic has affected the allocation of healthcare resources leading to the prioritisation of COVID-19 patients and suspending the equal access to healthcare services approach. We argue that we must look beyond this disruption in provision by examining existing barriers to access that have been amplified by the pandemic in order to understand the poorer (...) health outcomes for women in ethnic minority and migrant communities. The reflection focuses on racialised medical perceptions, gendered cultural norms including information barriers and stigma, and specific legal barriers. (shrink)

The aim of this paper is to assess the relevance of somatic evolution by natural selection to our understanding of cancer development. I do so in two steps. In the first part of the paper, I ask to what extent cancer cells meet the formal requirements for evolution by natural selection, relying on Godfrey-Smith’s (2009) framework of Darwinian populations. I argue that although they meet the minimal requirements for natural selection, cancer cells are not paradigmatic Darwinian populations. In the second (...) part of the paper, I examine the most important examples of adaptation in cancer cells. I argue that they are not significant accumulations of evolutionary changes, and that as a consequence natural selection plays a lesser role in their explanation. Their explanation, I argue, is best sought in the previously existing wiring of the healthy cells. (shrink)

This paper studies the capture of organisms and materials in soil construction – a branch of ecological engineering dedicated to making soil in order to compensate for soil degradation. This approach takes all organisms to be ‘ecosystem engineers’, and often refers to earthworms as ‘collaborators’ in making soil. I examine the claim that such a convocation of worms amounts to a redistribution of agency and the underlying assumption that form-taking is the shaping of raw matter according to pre-existing forms. Drawing (...) on processual anthropology, I question the distinction between living and material components of soils, and between growing and making. I elaborate on soil scientists’ description of soil growth as pedogenesis in order to propose a view in which soil materials, along with organisms, participate in soil’s transformative and generative fluxes. I envisage the process as a concrescence, an experimentation that brings humans, worms, and soil materials together in new ways. (shrink)

Costs at the end of life disproportionately contribute to health care costs in the United States. Addressing these costs will therefore be an important component in making the U.S. health care system more financially sustainable. In this paper, we explore the moral justifications for having discussions of end-of-life costs in the doctor-patient encounter as part of an effort to control costs. As health care costs are partly shared through pooled resources, such as insurance and taxation, and partly borne by individuals (...) through out-of-pocket expenses, we separate our defense for, and approach to, discussing both pooled and individual aspects of cost. We argue that there needs to be a shift away from formulating the options as a dichotomous choice of paying attention to end-of-life costs versus ignoring such costs. The question should be how personal costs will be managed and how societal expenditures should be allocated. These are issues that we believe patients care about and need to have addressed in a manner with which they are comfortable. Conversations about how money will be spent at the end of life should begin before the end is near. We propose discussing costs from the onset of chronic illness and incorporating financial issues in advance care planning. Through these approaches one can avoid abruptly and insensitively introducing financial issues at the very conclusion of a person's life when one would prefer to address the painful and important issues of spiritual and existential loss that are appropriately the focus when a person is dying. (shrink)

The cost of health care at the end of life accounts for a high proportion of total health care costs in the United States. The percentage of Medicare payments attributable to patients in their last year of life was 28.3% in 1978 and has remained substantially the same at 25.1% in 2006. This indicates how little progress has been made in containing these costs, though doing so will be important to promote a financially sustainable health care system. These expenditures also (...) highlight the prospect that efforts to reduce health care costs overall are likely to disproportionately affect the care patients receive at the end of life. (shrink)

Previous research suggests that social anxiety symptoms are maintained and intensified by inflexible emotion regulation (ER). Therefore, we examined whether trait-level social anxiety moderates ER flexibility operationalised at both between-person (covariation between variability in emotional intensity and variability in strategy use across occasions) and within-person (associations between emotional intensity and strategy use on a given day) levels. In a sample of healthy college-aged adults (N = 185, Mage = 21.89), we examined overall and emotion-specific intensities (shame, guilt, anxiety, anger, sadness) (...) and regulatory strategies (i.e. experiential avoidance, expressive suppression, and rumination) in response to each day’s most emotionally intense event over 6 days. During the study period, we found a positive association between variability in emotional intensity and variability of experiential avoidance in individuals with lower, rather than higher, levels of trait social anxiety after controlling for key covariates (i.e. gender, personality traits, and stress exposure). However, we did not find evidence for the moderating role of trait social anxiety in ER flexibility assessed at within-person levels. Our findings highlight the need to delineate dynamic ER flexibility across everyday events. (shrink)

Certitudes et incertitudes du déterminisme.--La crise de l'esprit.--Le drame.--La tour de Babel.--Le crépuscule.--L'aube.

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Kant and the Capacity to Judge; Sensibility and Discursivity in the Transcendental Analytic of the Critique of Pure Reason by Beatrice LonguenesseMichelle GreerBeatrice Longuenesse. Kant and the Capacity to Judge; Sensibility and Discursivity in the Transcendental Analytic of the Critique of Pure Reason. Translation by Charles T. Wolfe. Princeton, NJ: Princeton University Press, 1998. Pp. xv + 420. Cloth, $59.50.Kant and the Capacity to Judge is a translation (...) of Longuenesse’s Kant et Pouvoir de juger, although Longuenesse has revised and added to the original version. The central argument seeks to demonstrate the essential role played by the logical forms of judgment in the arguments of Kant’s first Critique. Longuenesse emphasizes straight away Kant’s efforts (in the Metaphysical Deduction) to deduce a set of pure concepts from the logical forms of judgment. Against many standard readings, she aims to reveal the very “tight” connection between this attempt and subsequent arguments in the Transcendental [End Page 372] Analytic. That Kant takes the functions of judgment to be relevant to these arguments is hardly a novel claim. The originality of Longuenesse’s work, however, stems both from the central and pervasive role she assigns to the logical forms of judgment, and from the impressive, painstaking effort she makes to sustain the close connection between these forms and Kant’s subsequent arguments. According to Longuenesse, any proper understanding of the arguments of the Transcendental Analytic absolutely depends upon relating these “down to the minutest details of their proofs,” to the role of the logical forms (5).These minute details do not escape Longuenesse in her subsequent elaboration on this original thesis. Given the length and detail of her work, I can only highlight a few of the central points and strategies. One should note from the outset, however, that the detail and the scholarship evinced to support her claims constitute much of what is of value in the book. Many of these “supporting arguments” and discussions, which include efforts to trace Kantian conceptions back to their historical/philosophical origins, stand in their own right as independent contributions to Kant scholarship and interpretation.The work is divided into three parts. The first part is essentially propaedeutic. Longuenesse begins by drawing a distinction between the potential or capacity to judge and judgement itself (i.e., the “actualization” of this judgmental capacity under [externally grounded] sensory stimulation) (7). Taking this distinction as her cue, Longuenesse seeks to reveal the way in which the line of argumentation in the transcendental analytic presents an extended investigation into the formal capacity (ibid). The centrality of the logical forms of judgment is secured early on by assigning them a substantive role in the very presentation of something in intuition “as” an “object.” Insofar as she assigns this role to the logical forms themselves, her account clearly undercuts the primary function of the categories in this regard. Relevant here is Longuenesse’s construal of “appearances” as the intentional correlates of our representational capacities and activities (cf. 20–21). Given this, the problem now motivating the transcendental deduction is how to make sense of the relation between this “internalized” object of (indeterminate) empirical intuition (the appearance) and the object corresponding to intuition which concepts allow one to think in a determinate way (the phenomenon). This ability to think the object in a determinate fashion appears to be the essential contribution made by judgement.These preliminary considerations ground Longuenesse’s efforts (in Part Two) to isolate and examine the discursive activity of judgment. Longuenesse stresses the reflective (and not simply the determinative) role of judgment and its forms. Indeed, she suggests that concepts (not merely empirical concepts, but also the pure concepts of the understanding themselves) are formed by reflecting (through acts of comparison, reflection, and abstraction) on the “sensible given.” Drawing extensively from the Logic, she interestingly argues that the form of judgment itself carries with it some inherent claim to objectivity. Thus, objectivity is folded into the formal activity of judging by being identified as a “normative propensity” inherent in every judgment by virtue of its form alone (87–88). Longuenesse accordingly eschews efforts to downplay the role of the logical use of the... (shrink)

Responding to the complicated conditions produced by both the Constantinian Revolution and the collapse of the Roman Empire in the West, Augustine concerned himself not so much with “earthly transitions” as with the only transition that he believed had final significance: the transition of Christ from death to life.

This article unravels the complex set of financial dealings that are at the heart of the Enron story and follows the story through the highs and lows of Enron share prices. The key players are identified and their roles described. Apart from the financial and accounting issues, the Enron story also raises a wide range of ethical issues including corporate governance, organisational culture and ethical leadership and scrutiny. These are discussed in the article. It might be argued that Enron could (...) never have got away with some of its practices if it had been operating in Europe. The article concludes that this view may be naïve, particularly in the light of recent media disclosures of the UK Labour government's continuing flirtation with business donations. The Enron story raises serious considerations in a whole host of financial, economic, political and ethical areas. As the Enron story continues to unfold, an article of this type can only begin to scratch the surface of some of these issues and to lay them out for further investigation. (shrink)

De part en part traversé par le mythe, le Commentaire sur la République du Néoplatonicien Proclus accorde forcément une attention soutenue au symbole. Cet article se propose de mettre en lumière deux types de symbolisme que l’on trouve dans ce Commentaire. Le premier, «non imitatif», reconfigure significativement l’héritage des Formes intelligibles platoniciennes; le second, tiré des Oracles chaldaïques, consiste en une «intériorisation» du symbole. Les deux symbolismes se rejoignent en ce qu’ils impliquent une sympathie profonde entre toutes choses, et présupposent (...) la communication préalable des symboles tant dans la genèse que dans l’interprétation du mythe inspiré. (shrink)

This paper presents an extensional account of manyand few that explains data that have previously motivated intensional analyses of these quantifiers :599–620, 2000). The key insight is that their semantic arguments are themselves set intersections: the restrictor is the intersection of the predicates denoted by the N’ or the V’ and the restricted universe, U, and the scope is the intersection of the N’ and V’. Following Cohen, I assume that the universe consists of the union of alternatives to the (...) nominal and verbal predicates, where an alternative to a property ψ is one that shares a pragmatic presupposition with ψ, and a pragmatic presupposition is one that is selected by context from a set of potential presuppositions associated with the sentence. A many/few-quantified sentence is then true iff the proportion of the scope to the restrictor is greater/less than some threshold, n. In addition to explaining various problematic cases from the literature, the analysis shows how the readings of a many/few-quantified sentence can be derived from the same syntactico-semantic structure, it being unnecessary to claim lexical or structural ambiguity. The analysis also provides strong support for the idea that natural language quantification is always purely extensional. (shrink)

In response to Germain argument that evolution by natural selection has a limited explanatory power in cancer, Lean and Plutynski have recently argued that many adaptations in cancer only make sense at the tumor level, and that cancer progression mirrors the major evolutionary transitions. While we agree that selection could potentially act at various levels of organization in cancers, we argue that tumor-level selection is unlikely to actually play a relevant role in our understanding of the somatic evolution of human (...) cancers. (shrink)

Background Achieving meaningful consent can be challenging, particularly in contexts of diminished literacy, yet is a vital part of participant protection in global health research. Method We explored the challenges and potential solutions of achieving meaningful consent through a qualitative study in a predominantly hill tribe ethnic minority population in northern Thailand, a culturally distinctive population with low literacy. Semi-structured interviews were conducted with 37 respondents who had participated in scrub typhus clinical research, their family members, researchers and other key (...) informants. A thematic analysis was conducted. Results Our analysis identified four interrelated themes surrounding participants’ ability to give consent: varying degrees of research understanding, limitations of using informal translators, issues impacting decisions to join research, and voluntariness of consent. Suggestions for achieving more meaningful consent included the use of formal translators and community engagement with research populations. Conclusions Participant’s agency in decision making to join research should be supported, but research information needs to be communicated to potential participants in a way that they can understand. We found that improved understanding about the study and its potential benefits and harms goes beyond literacy or translation and requires attention to social and cultural factors. (shrink)

In its last round of publications in September 2012, the Encyclopedia Of DNA Elements (ENCODE) assigned a biochemical function to most of the human genome, which was taken up by the media as meaning the end of ‘Junk DNA’. This provoked a heated reaction from evolutionary biologists, who among other things claimed that ENCODE adopted a wrong and much too inclusive notion of function, making its dismissal of junk DNA merely rhetorical. We argue that this criticism rests on misunderstandings concerning (...) the nature of the ENCODE project, the relevant notion of function and the claim that most of our genome is junk. We argue that evolutionary accounts of function presuppose functions as ‘causal roles’, and that selection is but a useful proxy for relevant functions, which might well be unsuitable to biomedical research. Taking a closer look at the discovery process in which ENCODE participates, we argue that ENCODE’s strategy of biochemical signatures successfully identified activities of DNA elements with an eye towards causal roles of interest to biomedical research. We argue that ENCODE’s controversial claim of functionality should be interpreted as saying that 80 % of the genome is engaging in relevant biochemical activities and is very likely to have a causal role in phenomena deemed relevant to biomedical research. Finally, we discuss ambiguities in the meaning of junk DNA and in one of the main arguments raised for its prevalence, and we evaluate the impact of ENCODE’s results on the claim that most of our genome is junk. (shrink)

In the current career landscape and labor market, career transitions have become a critical aspect of career development and are significant for Human Resource Development research and practice. Our research examines the type of support used during different career transitions and who can provide that support to women in career transition. We investigated four types of social support—emotional, appraisal, informational, and instrumental—and their roles in five types of career transitions: school-to-work transition, upward mobility transition, transition to a new profession, transition (...) to entrepreneurship, career re-entry transition, and transition to retirement. We analyzed 80 journal articles using directed content analysis, cross-tabulation, and nonparametric statistical tests. Instrumental support appears to be the most commonly documented type of social support in this career transition literature. Appraisal support was consistently documented least for each type of career transition. Our results may highlight the importance of personal connections and internal resources in successful career transitions for women. Based on our findings, we offer a model of women's social support network for career transitions and advocate for expanded networks of social support for women anticipating and during career transitions. The results of our study contain insights for how women can be supported in transitioning to the next career experience. We conclude with suggestions for future research. (shrink)

Gil Germain's Spirits in the Material World reflects on the vital role technology plays in liberating humankind from the real world of space and time, and examines the broad implications of this development for contemporary society. Germain argues that we ought to be wary of our spiritual sojourn and suggests ways to offset technology's otherworldly impulse.

Sinous voulions tirer une ligne d'unité à travers les branches si disparates qui se sont épanouies sur les racines cartésiennes, nous pourrions affirmer que l'homme est rentré en lui-même et de plus en plus profondément jusqu'à nos jours. Son regard s'est détourné d'un objet extérieur pour considàrer le produit intérieur de son acte d'esprit, puis pour essayer de pénétrer dans le mystère même de cet acte. L'homme s'est vu responsable de l'homme. Son existence lui est donnée mais il ne peut (...) la maintenir sans lui fournir une forme, une essence dont la spécification dépendra de son “je” libre. Tout un éventail d'humanismes s'est alors déployé à partir d'une concrétude enfouie irrévocablement et désespérément dans la condition charnelle jusqu'à la concrétude la plus spirituelle de la pensée réflexive contemporaine. En un mot, l'histoire de la philosophic moderne devient l'histoire de la prise de conscience de l'immanence. (shrink)

Dans son livre American Philosophy and the Future, Michael Novak nous rappelle que nous vivons sous la menace des conflits nucléaires. Si nous n'y prenons garde, nous dit-il, nous serons bientôt dans l'impossibilité de philosopher. Cet avertissement a de quoi nous étonner. Y aurait-il des bombes atomiques sans une philosophie de la bombe?Il y aurait bien d'autres objets, les uns plus extraordinaires que les autres, que nous apporte à un rythme toujours plus accéléré la nouvelle technologic et sur lesquels il (...) nous faudrait aussi philosopher et même davantage. Ainsi, un éditorial de Journal of the American Medical Association nous fait part des craintes que provoquent, chez médecins et biologistes, les expériences faites en vue de la fabrication des bébés-éprouvette — ‘test-tube babies’. (shrink)

A guide to the everyday decisions about right and wrong faced by physical scientists and research engineers. This book offers the first comprehensive guide to ethics for physical scientists and engineers who conduct research. Written by a distinguished professor of chemistry and chemical engineering, the book focuses on the everyday decisions about right and wrong faced by scientists as they do research, interact with other people, and work within society. The goal is to nurture readers' ethical intelligence so that they (...) know an ethical issue when they see one, and to give them a way to think about ethical problems. After introductions to the philosophy of ethics and the philosophy of science, the book discusses research integrity, with a unique emphasis on how scientists make mistakes and how they can avoid them. It goes on to cover personal interactions among scientists, including authorship, collaborators, predecessors, reviewers, grantees, mentors, and whistle-blowers. It considers underrepresented groups in science as an ethical issue that matters not only to those groups but also to the development of science, and it examines human participants and animal subjects. Finally, the book examines scientifically relevant social issues, including public policy, weapons research, conflicts of interest, and intellectual property. Each chapter ends with discussion questions and case studies to encourage debate and further exploration of topics. The book can be used in classes and seminars in research ethics and will be an essential reference for scientists in academia, government, and industry. (shrink)

Une modernité indigène: Ruptures et innovations dans les théories politiques japonaise du xviiie siècle, by Olivier Ansart, is a thoughtful, elegantly written book that offers valuable insights into Japanese political thought in an era that culminated in the Meiji Restoration. Despite the specific characteristics of the rigid centralized feudal structure of Tokugawa society, Ansart argues, political ideas generally associated with the advent of “modernity” in the West were generated indigenously in a context in which knowledge of the West was limited (...) primarily to science and technology.The main focus of the book is the thought of Kaiho Seiryō.1 Seiryō was inspired by two schools of thought that... (shrink)

The objective of this study is to analyze the writing of three neo-scholastic writers of the twentieth century -- Marcel Chossat, Pedro Descoqs, and Francis Cunningham -- who happen to dispute the prevailing view of Thomists that St. Thomas Aquinas does indeed hold a doctrine of thereal distinction of essence and existence in created being. The approach utilized will be basically historical: we start with the year 1910, the year in which Marcel Chossat rekindled the ever-smoldering embers of the essence-existence (...) controversy with his claim that Aquinas never held such a doctrine. In order to justify another treatment of what has been called “the endlessly rehashed question”, we try to show that the arguments put forth by the three thinkers in question an are based on considerable and weighty linguistic grounds which others in the debate have tended to dismiss. We conclude by saying that any discussion of the real distinction controversy must take a “linguistic turn” if it is to have any hope of being fruitful. (shrink)