Resistance to the drugs used in the treatment of many infectious diseases is increasing, while microbial infections are being found to be responsible for more life‐threatening diseases than previously thought. Despite a large investment in the invention and application of high‐throughput screening techniques involving miniaturization and automation, and a diverse array of strategies for designing and constructing various chemical libraries, relatively few new drugs have resulted. Natural products, however, have been a major source of drugs for centuries. Since some of (...) them are produced by organisms as a result of selection in favour of improved defense against competing deleterious microorganisms, in principle they would be less likely to incur resistance. Furthermore, the production of those defensive secondary metabolites is inducible because their original function is a response to environmental challenges. Moreover, symbioses, co‐habitation associations between two or more different species of organisms, are universal in nature, and the production of secondary metabolites by symbiotic microbes may be an important adaptation allowing microbes to affect their hosts. Therefore, co‐culture strategies, using combinations of plant cell–pathogenic microbes, plant cell–endophytes (or symbionts), and symbiont–pathogenic microbes, based on the principles of chemical defense and the known mechanisms of organism interactions, may be an efficient general approach in the search for new anti‐microbial drugs. BioEssays 26:808–813, 2004. © 2004 Wiley Periodicals, Inc. (shrink)

With the global pandemic of COVID-19, it has been striking psychological burdens on individuals. Under this background, more and more people get wellbeing by watching live broadcasts. However, the psychological mechanism behind this phenomenon is still a black box. This study finds that when people watch a live broadcast and interact with anchors and other people, an interaction ritual chain is formed, and emotional energy is generated, thus making people experience and understand the meaning of the live interaction ritual chains. (...) Under the effect of the meaning transfer model, people will generate wellbeing. Specifically, the basic meaning of live interaction drives people’s generation of wellbeing. The meanings of self-participation, self-display, self-concept, and self-renewal play a role in mediation in enhancing people’s wellbeing with the basic meaning of live broadcast interaction. (shrink)

This study examines the impact of chief executive officer ability on firms’ corporate social responsibility performance. We find that firms’ CSR performance increases with CEO ability. Specifically, firms with more able CEOs are associated with more socially responsible activities and fewer socially irresponsible activities, and are associated with more stakeholder CSR rather than third-party CSR. We further find that the positive relation between CEO ability and CSR is weakened for CEO who is also the chair of the board and for (...) CEO who is close to retirement; and is weakened when the CSR emphasis exerted by a firm’s external environment is high. Our results are robust after controlling for firm fixed effects and to the use of multiple measures of CSR performance and CEO ability. Overall, our evidence is consistent with our conjecture that more able CEOs have less career concerns so that these CEOs are more willing to undertake long-term investments in socially beneficial activities, leading to better CSR performance. (shrink)

How to mitigate stock price crash risk has become a focus in the theoretical and practical fields. Building on the work of Kim et al., this paper investigates the relation between corporate philanthropy and crash risk under the unique Chinese institutional background. The results show that both state ownership and the 2005 split share reform attenuate the mitigating effect of corporate philanthropy on crash risk. Specifically, the negative relation between corporate philanthropy and crash risk is less pronounced for state-owned enterprises (...) than for non-state-owned enterprises, and it is also less pronounced after firms accomplish the split share reform. Further, this effect is more pronounced for firms with greater financial risks and poorer performance. Our paper contributes to the growing literature on the determinants of stock price crash risk and the economic consequences of corporate philanthropy. It also offers useful guidance to firms that are seeking to reduce stock price crash risk in emerging markets. (shrink)

This study examines the relation between a firm’s business strategy and its corporate social responsibility performance. Using a comprehensive measure of business strategy based on the Miles and Snow theoretical framework, we find that firms following an innovation-oriented strategy are associated with better CSR performance than those following an efficiency-oriented strategy. Specifically, compared with defenders, prospectors engage in more socially responsible activities, fewer socially irresponsible activities, and perform better in both stakeholder- and third-party-related CSR areas. Taken together, our results suggest (...) that business strategy is an important determinant of CSR performance. Prospectors take advantage of CSR, as their innovation-oriented strategy allows them not only to benefit more from CSR, but also to have more tolerance for the uncertainty, risk, and long time-horizon associated with CSR engagement. (shrink)

This paper rigorously examines the primitive foundations of economic reasoning through a framework based on symbolic logic. Extending previous work, it formalizes economic conceptions (\(\mathbb{C}\)), symbols (\(s_i\)), and introduces a structured language (\(\mathcal{L_{\mathbb{C}}}\)) to define their formation and interpretation. Organized as a continuous chain of declarations and illustrations, the paper offers a concise, systematic approach to understanding the philosophy of economic reasoning through formal symbolic representations.

Drawing on social exchange theory and benevolent leadership literature, we show how the largesse associated with benevolent leadership can cause subordinates to feel obliged to undertake illegitimate tasks assignments that go beyond their job duties. The hypotheses are tested in a scenario experimental study and a multisource, time-lagged field survey. Both studies indicate that benevolent leadership evokes indebtedness in subordinates (called felt obligation), which is then indirectly related to their willingness to undertake illegitimate tasks. The second study shows that subordinates (...) who try to avoid actions that damage relationships (called disintegration avoidance) and those who feel job insecurity are most willing to perform illegitimate assignments. Practical implications for curbing workplace exploitation are discussed. (shrink)

The development of CSR reflects the level and characteristics of professional sports organizations, and the CSR of professional sports clubs varies among different countries and regions. In order to explore the content of the CSR of Chinese professional sports clubs in a more comprehensive and systematic way, this study organizes previous studies on the CSR of clubs in different countries and regions, and analyzes the differences between Chinese professional sports clubs and clubs in Europe, North America, Japan, and other countries (...) and regions. We collected the opinions of 20 experts through semi-structured interviews and combined them with the “Five in One” overall layout to construct and explain the CSR system of professional sports clubs in China in the new era, filling the gaps in research on this topic. Research suggests that social economic responsibility, social political responsibility, social cultural responsibility, social construction responsibility, and social ecological responsibility constitute the CSR system of professional sports clubs in China. Within a certain range, the larger the scale and stronger the comprehensive strength of a club, the stronger its ability to fulfill its responsibilities, the more targets it fulfills, and the richer its content. The institutional environment and social awareness may account for this difference, and in a government-led social environment or in the case of nationalized club ownership, the Chinese plan may be more applicable. Our research not only provides theoretical reference for subsequent research on the CSR content of professional sports clubs but also helps guide the CSR practice of clubs of different sizes, thereby promoting the exploration of diversified CSR development patterns of professional sports clubs in the academic community. (shrink)

Does the concept of political friendship make sense, and does cultivating political friendship among peoples strengthen universal peace? This article provides an Aristotelian account of political friendship as distinct from but analogous to personal friendship. Political friendships, founded on mutual recognition and respect, are characterized by consensual agreement about the fundamental terms of cooperation. While promoting such political friendship at the global level would be a measure to strengthen universal peace, another form of friendship, politicized friendship, is to be avoided, (...) as it is driven by rivalrous rather than equitable self-interest, and breeds political enmity and strife. Taking Aristotle's insights about political friendship to the global arena, the article considers Rawlsian peoples to be suitable subjects for political friendship. The duty of assistance and the duty to oppose outlaw states illuminate demands of political friendship among Rawlsian peoples that entail equity, power sharing and even sacrifice. (shrink)

In this paper, a normalized robust FOPID controller regulation algorithm is proposed. Only one parameter k is necessary to be tuned in the controller regulation process, so the proposed control algorithm is convenient to be applied on both fractional-order systems and integer-order systems. A robustness evaluation function is constructed based on the small gain theorem. Larger robustness evaluation function value will help the system achieve better robustness performance. Another parameter, β, is also available to serve as a tuning knob when (...) larger robust evaluation function value is needed. Therefore, the controlled systems can be stabilized and can achieve quite satisfactory robust control performance using the proposed algorithm. The corresponding robust analysis results are obtained according to different conditions in the discussion. For a special case of widely used fractional-order systems, the FOPI and FOID controllers are presented based on the same tuning scheme together with their robustness discussion. Some examples are shown to verify the robustness of systems controlled by the proposed algorithm. (shrink)

This is a linguistic study of two primary metaphors with the same target-domain concept, “IMPORTANCE IS SIZE” and “IMPORTANCE IS WEIGHT,” in English and Chinese. It is suggested that these two primary metaphors are derived from the OBJECT image schema, abstracted from our embodied, sensorimotor experience, especially our visual and tactile perception, in dealing with physical objects in everyday life. The study focuses on size and weight adjectives in both languages and on linguistic evidence in two areas: their lexicalizations of (...) the importance senses as found in the dictionaries, and their roles in the instantiation of the two primary metaphors in natural discourse as found in the corpora. Our further analysis also shows that the primary metaphors can be manifested without explicit use of size and weight words when relevant conceptual frames in the source, evoked by other words or images, are mapped onto the target domain, thus activating the relevant region of our encyclopedic knowledge and triggering off the primary metaphors in our conceptual system. We also construct a hypothetical mapping scheme for primary metaphors based on the OBJECT image schema, in which OBJECT is mapped onto its target via three of its fundamental dimensions: SIZE, WEIGHT, and SOLIDITY. It is hoped that this mapping scheme will benefit future comparative studies of primary metaphors across languages and cultures in a more systematic way. (shrink)

Although stressful life events have been shown to be a key risk factor for adolescent NSSI, the potential mediators and moderators of this relationship are unclear. Based on the social development theory and the organism-environment interaction model, we tested whether the link between stressful life events and adolescent NSSI was explained in part by deviant peer affiliation, and whether this process was buffered by gratitude. Chinese adolescents anonymously completed questionnaires to assess the study variables. The present study demonstrated that stressful (...) life events was linked to NSSI in part because of deviant peer affiliation, and high gratitude was a key protective factor to buffer this indirect effect. Teaching gratitude may be a helpful component of prevention and intervention programs to reduce adolescent NSSI. (shrink)

How do experiences of shame and guilt shape or reflect the ways in which the vanquished are reconciled (or not) to the new world order established by the victors? Shame and guilt are universal experiences in the emotional landscape of post-war politics, albeit for different reasons and with radically different political effects. An examination of Germany after 1918 and of Japan after 1945 reveals that experiences of shame and guilt may be pivotal for creating conditions of possibility for reconciliation marked (...) by political and moral transformation. This transformative potential of shame and guilt, however, is a double-edged sword. In threatening old identities, values and beliefs, experiences of shame and guilt may provoke defensive, reactionary and violent political responses, and thus may precipitate hideous rather than salutary transformations. Political leadership and political culture are crucial factors in shaping the kind of reconciliation — reactionary or transformative — as well as the specific nature of transformations that experiences of shame and guilt may motivate the vanquished to pursue. (shrink)

In recent studies, numerous anomalies against the weak and semi-strong-forms of efficient market hypothesis have been found insignificant after controlling the small-firm effect. We investigate whether the insider trading anomaly, a major anomaly against the strong-form of EMH, can survive after excluding small firms with a novel data set and document several new findings. We find a substantially larger number of insider purchases than sales, while the average volume of insider sales is much higher than the average volume of insider (...) purchases. Echoing recent US studies, we find that insider sales generate more abnormal returns than insider purchases do. We find much lower abnormal returns from insider trading than documented in the literature and the associated trading costs, which suggests that the market efficiency of individual stocks may depend on their sizes, and even the strong-form of EMH holds to a larger extent than previously recognized. (shrink)

Posttraumatic growth has been correlated with coping style among patients with breast cancer. However, to date, there is no consensus on the extent to which coping style is associated with PTG in patients with breast cancer. Therefore, we performed a meta-analysis to quantitatively synthesize previous findings. Based on the PRISMA method, this study employed a random effects model using the Stata software to calculate the pooled correlation coefficient and examined a range of moderators: cancer stage, publication type, participants’ age, and (...) coping style measurement tools. Relevant studies, published from inception to 9 March 2022, were identified through a systematic search in PubMed, Embase, Web of Science, PsycINFO, WANFANG DATA, Chinese National Knowledge Infrastructure, and China Science and Technology Journal Database databases. Finally, 20 studies involving 3,571 breast cancer patients were included in this investigation. The results showed a high positive relation between confrontation coping and PTG and a moderate positive relation between avoidance coping and PTG. Additionally, a moderate negative relation was identified between acceptance–resignation coping and PTG. Publication type and coping style measurement tools moderated the relation between coping style and PTG among breast cancer patients. The findings indicated that breast cancer patients should either confront the disease or avoid coping with it according to their disease state, which would facilitate better growth. More studies, especially, large prospective studies, are warranted to verify our findings.Systematic review registration[https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022319107], identifier [CRD42022319107]. (shrink)

Ethical culture construction is beneficial to maximize policy following behavior and avoid accidents of coal miners in an economic downturn. This paper examines the congruence between coal mine ethical culture values and miners’ moral values and the relationship with PFB. To shed light on this relationship, supervisor moral values act as a key moderator. We build on the initial structure of values to measure ECVs, MVs, and SMVs. At the same time, available congruence was defined to describe the relationship between (...) the two values. Drawing upon a survey of 267 miners in Chinese large state-owned coal mining enterprises, results revealed that ECVs–MVs congruence had a linear relationship with intrinsic PFB and a non-linear relationship with extrinsic PFB. These findings demonstrate that SMVs had a moderating effect on the relationship between ECVs–MVs congruence and extrinsic PFB. Thus, we continued to calculate the available congruence scope in tested enterprises. Furthermore, this study gives relative management proposals and suggestions to improve miners’ moral standards and to reduce coal mine accidents. (shrink)

In "The Variation of Chinese Literature and the Formation of World Literature" Shunqing Cao and Lu Zhai discuss how Chinese works of literature entered other countries' literary circles through variation, and became an essential part of world literature. Both ancient Chinese literature and contemporary Chinese literature have undergone textual circulation, language translation and cultural filtering before becoming part of world literature, all of which are the reasons why literary variation occurs. According to Cao and Zhai, the occurrence of variation is (...) a key factor for Chinese literature to become world literature, and an important foundation for the formation of world literature. A country's literature absorbs the characteristics of other countries' literature through variation, thus adapting to the cultural background and reading habits of other countries' readers in terms of language and style, in order to enter the world literature market. Variation may lead to a certain loss of nationality in literary works, and result in significant differences from the original texts. However, the formation of world literature does not come at the cost of eliminating nationality; variation facilitates the formation of world literature. (shrink)

People are known for good predictions in domains they have rich experience with, such as everyday statistics and intuitive physics. But how well can they predict for problems they lack experience with, such as the duration of an ongoing epidemic caused by a new virus? Amid the first wave of COVID-19 in China, we conducted an online diary study, asking each of over 400 participants to predict the remaining duration of the epidemic, once per day for 14 days. Participants’ predictions (...) reflected a reasonable use of publicly available information but were meanwhile biased, subject to the influence of negative affect and future time perspectives. Computational modeling revealed that participants neither relied on prior distributions of epidemic durations as in inferring everyday statistics, nor on mechanistic simulations of epidemic dynamics as in computing intuitive physics. Instead, with minimal experience, participants’ predictions were best explained by similarity-based generalization of the temporal pattern of epidemic statistics. In two control experiments, we further confirmed that such cognitive algorithm is not specific to the epidemic scenario and that minimal and rich experience do lead to different prediction behaviors for the same observations. We conclude that people generalize patterns in recent history to predict the future under minimal experience. (shrink)

COVID-19 has made it difficult to adopt traditional face-to-face psychological intervention under this situation because of the blocked down and social distancing, which brings big psychological crisis to the public among the global. To explore the emotional change of the public in China at the outburst of the pandemic at different phases, to establish an online working platform and create a new model of an online intervention to hold public emotions under pandemic, and test its effectiveness, so to give advisement (...) for government emergency management system. We established an online organization to work for this program ad innovated a model of online group counseling with online emotional support accompany group right after the outburst of a pandemic. We analyzed 53 OESAGs from February 10 to April 9, including 555 application forms, 253 feedback from members, and 139 feedback from group leaders by using NVivo and SPSS to explore the evolution and characteristics of public emotion during COVID-19 and the effectiveness of OESAG. Our results showed that the emotional changes of members ranged from shock to depression to positive. The public's emotions swiftly changed from stress, anxiety, and isolation, to the hope of returning to work or finding a job during the pandemic with the help of OESAG. OESAG has effectively regulated the negative emotions of members by conducting psychological crisis intervention to provide members a space to communicate with each other, especially the female and frontline staff. Policy makers can set up an online systematic psychological crisis intervention system as soon as possible to make up for the lack of psychological assistance in the emergency management system. (shrink)

Impossible de considérer la promotion, l’essor et le développement des idées libérales en Chine au xx e siècle sans prendre en compte la figure de Hu Shi (1891-1962) et l’influence que son œuvre exerça. Pendant toute sa vie intellectuelle, Hu Shi se tint au premier rang des intellectuels chinois désireux de moderniser leur pays. Parti se former aux États-Unis très tôt, il concentra ses recherches sur les (r)évolutions littéraires et entreprit d’analyser l’histoire de la philosophie chinoise avec les méthodes scientifiques (...) occidentales. Il entendait non seulement changer les façons de parler et d’écrire dans le monde académique, mais encore les styles de pensée et de vie au sein de la population chinoise. Il devint l’un des plus prestigieux intellectuels de la Chine moderne, en s’engageant activement dans la vie politique. Il poursuivitl’idéal d’une « bonne gouvernance », même en régime de parti unique. L’invasion par le Japon interrompit ses efforts et la guerre civile le mit en difficulté, quoiqu’il ait aidé dans une certaine mesure à restaurer l’autorité d’une administration centrale indispensable à un pays en voie de développement au territoire immense et à la population énorme : les efforts à déployer pour le moderniser vite et fort sont à cette mesure. Hu Shi dut quitter la Chine continentale. Dans les dernières années de sa vie, il fut un symbole de la relation entre les États-Unis et le régime du Kuomintang à Taïwan, mais nombre de ceux qu’il avait formés et qui étaient restés en Chine continentale critiquaient sa position, au sein de la communauté académique. Or Hu Shi prit lui-même ses distances avec le Kuomintang (KMT dans cet article), en levant toujours haut la bannière du libéralisme et d’une « Chine libre ». Classification JEL : B13, B31, N25, P26. (shrink)

In the following paper I discuss the under-appreciated role that the concept of the morally serious person plays in Aristotle’s moral philosophy. I argue that the conventional English rendering of spoudaios as “good” has a tendency to cut us off from important nuances in Aristotle’s consideration of the virtuous person. After discussing aspects of his use of the concept in the Nicomachean Ethics and the Politics I dismiss a misunderstanding of seriousness as a kind of morally indifferent personality trait. I (...) close by briefly reflecting on how an absence of moral seriousness characterizes much contemporary moral theorizing and produces what Anscombe described as the “corrupt mind.”. (shrink)

Although the ethical judgment of consumers in the United States and other industrialized countries has received considerable attention, consumer ethics in Asian-market settings have seldom been explored. The purchase and making of counterfeit products are considered common, but disreputable, attributes of Southeast Asian consumers. According to the Association of South-East Asian Nations (ASEAN), Indonesia ranks third among the leading countries of counterfeit items in Asia. Retail revenue losses attributed to counterfeiting amounted to US $183 million in 2004. Therefore, elucidating the (...) ethical perspectives of Indonesian consumers is an effective means of clarifying an important cultural influence on consumer behavior. This exploratory study of 230 Indonesians has many meaningful findings. First, certain personal attitudes apparently affect the ethical judgments of Indonesian consumers. Second, Indonesian consumers who exhibited high ethical concern over actively benefiting from illegal actions had high levels of materialism and idealism, as well as low levels of relativism. Third, materialism, idealism, and relativism significantly influenced whether benefits were created from actively engaging in some questionable activities (DELEGAL). Analytical results indicated that Indonesians with high materialism and relativism were more likely to engage in actions that were questionable but legal. Finally, consumer ethics were compared by applying demographic variables such as gender, age, education, religion, and occupation, indicating that all variables significantly varied except for religion. (shrink)

This chapter will pin down the most outlandish image of Confucius in Chinese history, which comes from a corpus particular to the intellectual and political context of the first two centuries CE China, the apocrypha (chenwei 讖緯). The corpus developed the image of Confucius from earlier ones, such as a thinker, a sage, and an unsuccessful politician. Moreover, apocrypha reflect the intellectual and political changes of the time, especially a growing enthusiasm for an ideal society based on the Five Classics (...) and the restoration of the Han dynasty. The image of Confucius fluctuates in accordance with these changes and becomes that of a prophet and messenger of Heaven who not only encoded his political teaching in his work, the Annals of Spring and Autumn, but also foretold the ascendance of the ruling Liu family. His seemingly outlandish image was rooted in knowledge shared amongst scholars of that time. (shrink)

本书考察了以理学家, 科技实践家, 医学研究者及人文学等为代表的典型人物的科技思想, 比较清晰地勾勒出金元科技思想史的发展脉络, 并对金元科技思想的历史演变及宗教特征进行了新的学术审视和反思. 本书分为上下两卷, 本册为上卷.