いま最も注目される気鋭の哲学者、待望の初対談集。第一線で活躍する論客たちと、哲学、文学、社会、精神医学、サブカルチャーなどを横断し、現代の問題を縦横無尽に語りつくす。思考の前衛がここにある!

This article provides a preliminary exploration into the relationship between the bodily senses and race. Seeking insight into what Merleau-Ponty called a body-subject—a lived, knowing body that is aware and reflective of its perceptual experience and actively participates in the construction of reality—it explores the role of the bodily senses in constituting the ideological universe of race. Approaching the body as an anchor of sensory apparatus that is cultivated to confirm and uphold the social and ideological existence of race, it (...) explores how we cultivate, activate, and materialize the historically specific bodies that actively perceive race as difference and participate in the social reality organized by race. Examples of colorblind ideology and racialized pain are used to substantiate the claim that our sensory participation in reality is integral to maintaining what we call race. (shrink)

Diese Abhandlung verteidigt gegen die heute vorherrschenden realistischen Interpretationen des kantischen transzendentalen Idealismus eine anti-realistische Zwei-Welten-Interpretation. Durch konkrete Textanalysen wird gezeigt, dass die realistische Interpretation an der Antinomienlehre und dem vierten Paralogismus (A) scheitern muss, während die anti-realistische Interpretation erlaubt, die Kritik der reinen Vernunft im Ganzen zu einer kohärenten Sinneinheit zu strukturieren. Anschließend wird der konkrete Gehalt von Kants anti-realistischer Ontologie der raumzeitlichen Wirklichkeit erhellt. Dafür entwickelt der Verfasser eine intuitionistische Wahrheitskonzeption (ein empirisches Gegenstück der Wahrheitskonzeption des mathematischen Intuitionismus), (...) kombiniert mit der Superassertibilität à la Crispin Wright. Die von Michael Dummett bereit gestellte Begrifflichkeit "Realismus/Anti-Realismus‟ erweist sich als fruchtbar nicht nur für die Analyse der kantischen Position selbst, sondern auch für ein klares Verständnis der mannigfaltigen Interpretationsansätze des transzendentalen Idealismus. (shrink)

ABSTRACT In this brief article, we examine the document entitled Universal Draft Declaration on Bioethics and Human Rights, published by UNESCO in June 2005. We examine it in terms of its content and its appropriate role in global bioethics movements in the future. We make clear our view on the Declaration: the Declaration, despite a variety of serious problems, remains a valuable bioethical document and can contribute in substantial ways to the happiness of people throughout the world.

ABSTRACT In this brief article, we examine the document entitled Universal Draft Declaration on Bioethics and Human Rights, published by UNESCO in June 2005. We examine it in terms of its content and its appropriate role in global bioethics movements in the future. We make clear our view on the Declaration: the Declaration, despite a variety of serious problems, remains a valuable bioethical document and can contribute in substantial ways to the happiness of people throughout the world.

ABSTRACT In this brief article, we examine the document entitled Universal Draft Declaration on Bioethics and Human Rights, published by UNESCO in June 2005. We examine it in terms of its content and its appropriate role in global bioethics movements in the future. We make clear our view on the Declaration: the Declaration, despite a variety of serious problems, remains a valuable bioethical document and can contribute in substantial ways to the happiness of people throughout the world.

This study attempted to answer the question of how to share the values and ethics of youth work among practitioners and with policymakers, funders, and society. Although social interest in youth support in Japan has been on rise recently due to the increase number of difficulties surrounding young people, the ‘ethics and values’ in practice and in the field can be driven by the neoliberal social and political trends present in our society. This study presents a way to resist and (...) counter the penetration of neoliberal practical ethics and organisational management through the process of visualising, sharing and legitimising the ‘practical ethics and values’ embedded in the fields where youth work has been developed with young people. This is the research-based practice of ‘practitioners collectively telling, writing, sharing, and communicating the stories of practice’. (shrink)

To investigate whether people with social anxiety have less actual and “anticipatory” anxiety when interacting with a robot compared to interacting with a person, we conducted a 2 × 2 psychological experiment with two factors: social anxiety and interaction partner. The experiment was conducted in a counseling setting where a participant played the role of a client and the robot or the confederate played the role of a counselor. First, we measured the participants’ social anxiety using the Social Avoidance and (...) Distress Scale, after which, we measured their anxiety at two specific moments: “anticipatory anxiety” was measured after they knew that they would be interacting with a robot or a human confederate, and actual anxiety was measured after they actually interacted with the robot or confederate. Measurements were performed using the Profile of Mood States and the State–Trait Anxiety Inventory. The results indicated that participants with higher social anxiety tended to feel less “anticipatory anxiety” and tension when they knew that they would be interacting with robots compared with humans. Moreover, we found that interaction with a robot elicited less tension compared with interaction with a person regardless of the level of social anxiety. (shrink)

Histone post‐translational modifications (PTMs) alter the chromatin architecture, generating “open” and “closed” states, and these structural changes can modulate gene expression under specific cellular conditions. While methylation and acetylation are the best‐characterized histone PTMs, citrullination by the protein arginine deiminases (PADs) represents another important player in this process. In addition to “fine tuning” chromatin structure at specific loci, histone citrullination can also promote rapid global chromatin decondensation during the formation of extracellular traps (ETs) in immune cells. Recent studies now show (...) that PAD4‐mediated citrullination of histone H1 at promoter elements can also promote localized chromatin decondensation in stem cells, thus regulating the pluripotent state. These observations suggest that PAD‐mediated histone deimination profoundly affects chromatin structure, possibly above and beyond that of other PTMs. Additionally, these recent findings further enhance our understanding of PAD biology and the important contributions that these enzymes play in development, health, and disease. (shrink)

In the United States alone, the prevalence of AD is expected to more than double from six million people in 2019 to nearly 14 million people in 2050. Meanwhile, the track record for developing treatments for AD has been marked by decades of failure. But recent progress in genetics, neuroscience and gene editing suggest that effective treatments could be on the horizon. The arrival of such treatments would have profound implications for the way we diagnose, triage, study, and allocate resources (...) to Alzheimer’s patients. Because the disease is not rare and because it strikes late in life, the development of therapies that are expensive and efficacious but less than cures, will pose particular challenges to healthcare infrastructure. We have a window of time during which we can begin to anticipate just, equitable and salutary ways to accommodate a disease-modifying therapy Alzheimer’s disease. Here we consider the implications for caregivers, clinicians, researchers, and the US healthcare system of the availability of an expensive, presymptomatic treatment for a common late-onset neurodegenerative disease for which diagnosis can be difficult. (shrink)

Improving public understanding and acceptance are critical for promoting coronavirus vaccination. However, how to promote COVID-19 vaccine programs remains controversial due to various ethical issues. This study, thus, aimed to survey the acceptance of COVID-19 vaccines among Japanese citizens and discuss relevant ethical issues. A cross-sectional survey was conducted via an online platform. An anonymous, quantitative, self-administered online questionnaire was sent to 6965 registered Japanese residents, which included questions regarding the respondent’s general knowledge, experience, and opinions of vaccines, vaccine development, (...) COVID-19, and COVID-19 vaccines. Of the 1569 respondents, 730 and 839 were categorized into the younger and older groups, respectively. Most of the respondents possessed general knowledge of COVID-19 vaccines and their features. Of the respondents, 57.8% definitely agreed or somewhat agreed to receive COVID-19 vaccines. The older group showed significantly greater willingness to receive vaccines and higher literacy regarding vaccines in general. Possible reasons for the older group’s greater willingness to receive COVID-19 vaccines are a high risk of severe COVID-19 infection and their past accumulated experience of receiving various vaccinations. Although active public intervention could increase vaccination rates, most of the respondents did not agree with mandatory vaccination. Furthermore, a gap between the participants in the COVID-19 vaccine trials and the prioritized population in real-world vaccination should be adjusted in future vaccine development. (shrink)

We found that children sometimes abused a social robot placed in a shopping mall hallway. They verbally abused the robot, repeatedly obstructed its path, and sometimes even kicked and punched the robot. To investigate the reasons for the abuse, we conducted a field study in which we interviewed visiting children who exhibited serious abusive behaviors, including physical contact. We analyzed interview contents to determine whether the children perceived the robot as human-like, why they abused it, and whether they thought that (...) the robot would suffer from their abusive behavior. We obtained valid interviews from 23 children over 13 days of observations. We found that 1) the majority of the children engaged in abuse because they were curious about the robot’s reactions or enjoyed abusing it and considered it human-like, and 2) about half of them believed the robot was capable of perceiving their abusive behaviors. (shrink)

Name der Zeitschrift: Kant-Studien Jahrgang: 107 Heft: 2 Seiten: 389-390.

Name der Zeitschrift: Kant-Studien Jahrgang: 107 Heft: 2 Seiten: 389-390.

The goal of Chiba’s book is to answer the following question: Is Kant’s ‘transcendental idealism’ ‘realism’ or ‘idealism’? (p. 2) Chiba concludes that Kant is an anti-realist: objects do not exist independently of our cognition. Chiba’s book contains a lot of interesting and precise analysis of parts of Kant’s argument in the Critique of Pure Reason. So it should be clear that the following remarks, although they express disagreement or reservation, are in no sense meant to hold (...) back anyone from reading Chiba’s book. The contrary is the case: although I do not agree with everything Chiba affirms and defends, I can recommend his in its detail very informative dissertation to anyone who is interested in the attempt to link Kant’s theory to the contemporary ‘realism’ debate. (shrink)