The Ontology for Biomedical Investigations (OBI) is an ontology that provides terms with precisely defined meanings to describe all aspects of how investigations in the biological and medical domains are conducted. OBI re-uses ontologies that provide a representation of biomedical knowledge from the Open Biological and Biomedical Ontologies (OBO) project and adds the ability to describe how this knowledge was derived. We here describe the state of OBI and several applications that are using it, such as adding semantic expressivity to (...) existing databases, building data entry forms, and enabling interoperability between knowledge resources. OBI covers all phases of the investigation process, such as planning, execution and reporting. It represents information and material entities that participate in these processes, as well as roles and functions. Prior to OBI, it was not possible to use a single internally consistent resource that could be applied to multiple types of experiments for these applications. OBI has made this possible by creating terms for entities involved in biological and medical investigations and by importing parts of other biomedical ontologies such as GO, Chemical Entities of Biological Interest (ChEBI) and Phenotype Attribute and Trait Ontology (PATO) without altering their meaning. OBI is being used in a wide range of projects covering genomics, multi-omics, immunology, and catalogs of services. OBI has also spawned other ontologies (Information Artifact Ontology) and methods for importing parts of ontologies (Minimum information to reference an external ontology term (MIREOT)). The OBI project is an open cross-disciplinary collaborative effort, encompassing multiple research communities from around the globe. To date, OBI has created 2366 classes and 40 relations along with textual and formal definitions. The OBI Consortium maintains a web resource providing details on the people, policies, and issues being addressed in association with OBI. (shrink)

Much recent research has sought to uncover the neural basis of moral judgment. However, it has remained unclear whether "moral judgments" are sufficiently homogenous to be studied scientifically as a unified category. We tested this assumption by using fMRI to examine the neural correlates of moral judgments within three moral areas: (physical) harm, dishonesty, and (sexual) disgust. We found that the judgment ofmoral wrongness was subserved by distinct neural systems for each of the different moral areas and that these differences (...) were much more robust than differences in wrongness judgments within a moral area. Dishonest, disgusting, and harmful moral transgression recruited networks of brain regions associated with mentalizing, affective processing, and action understanding, respectively. Dorsal medial pFC was the only region activated by all scenarios judged to be morally wrong in comparison with neutral scenarios. However, this region was also activated by dishonest and harmful scenarios judged not to be morally wrong, suggestive of a domain-general role that is neither peculiar to nor predictive of moral decisions. These results suggest that moral judgment is not a wholly unified faculty in the human brain, but rather, instantiated in dissociable neural systems that are engaged differentially depending on the type of transgression being judged. (shrink)

This book offers a complete rethink of the institutional limits and possibilities of deliberative democracy and legitimacy. Examining several unresolved problems at the core of deliberative democratic theory, this volume will be vital reading for deliberative democratic theorists and public policy makers.

This article integrates arguments and evidence from my 2019 monograph Heart to Heart: How Your Emotions Affect Other People. The central claim is that emotions operate as processes of relation alignment that produce convergence, complementarity, or conflict between two or more people’s orientations to objects. In some cases, relation alignment involves strategic presentation of emotional information for the purpose of regulating other people’s behaviour. In other cases, emotions consolidate from socially distributed reciprocal adjustments of cues, signals, and emerging actions without (...) any explicit registration or communication of emotional meaning by parties to the exchange. The relation-alignment approach provides a fresh perspective on issues relating to emotion’s interpersonal, intragroup, and organizational functions and clarifies how emotions are regulated for social purposes. (shrink)

Professor Parkinson's book on Spinoza's theory of knowledge makes a serious attempt to consider this theme in isolation. The author argues that an understanding of this particular theory is a prerequisite to any understanding of Spinoza's theory of ethics or his metaphysical views. The text also discusses Spinoza's interests, especially the influence of science on the development of his thought, and ultimately provides a critical account of the philosopher's methodology, theory of truth, and theory of differing kinds of knowledge.

This article discusses contemporary social psychological approaches to the social relations and appraisals associated with specific emotions; other people’s impact on appraisal processes; effects of emotion on other people; and interpersonal emotion regulation. We argue that single-minded cognitive perspectives restrict our understanding of interpersonal and group-related emotional processes, and that new methodologies addressing real-time interpersonal and group processes present promising opportunities for future progress.

This paper is concerned with some limitations of the vignette methodology used in contemporary appraisal research and their implications for appraisal theory. We focus on two recent studies in which emotional manipulations were achieved using textual materials, and criticise the investigators' apparent implicit assumption that participation in everyday social reality is somehow comparable to reading a story. We take issue with three related aspects of this cognitive analogy between life and its narrative representation, by arguing that emotional reactions in real (...) life are not necessarily mediated by symbolic processes, that people are involved participants of real life rather than neutral observers, and that in real life people's evaluations and emotions are typically part of an ongoing dialogue rather than the expression of a soliloquy. Results from these studies of emotional vignettes therefore tend to overestimate the importance of constructive, abstract, and individualistic processes in the everyday causation of social emotions. In real life, people do not necessarily have to calculate, transform, or internally represent the meaning of the dynamic situation in order to make emotional sense of what is happening to them in the social world. (shrink)

This paper presents a new approach to the demarcation of social emotions, based on their dependence on social appraisals that are designed to assess events bearing on social concerns. Previous theoretical attempts to characterize social emotions are compared, and their inconsistencies highlighted. Evidence for the present formulation is derived from theory and research into links between appraisals and emotions. Emotions identified as social using our criteria are also shown to bring more consistent consequences for social behavior than nonsocial emotions. We (...) conclude by considering ways of validating and refining our classification. (shrink)

Recent studies have used self-report methods to defend a close associative or causal connection between appraisal and emotion. The present experiments used similar procedures to investigate remembered experiences of reasonable and unreasonable anger and guilt, and of nonemotional other-blame and selfblame. Results suggest that the patterns of appraisal reported for reasonable examples of emotions and for situations where there is a near absence of emotion may be highly similar, but that both may differ significantly from the appraisal profiles reported for (...) unreasonable examples of the same emotions. Further, relevant appraisals were not always identified by participants as the most influential determinants of guilt and anger. These findings demonstrate either that the relationship between certain appraisals and emotions is less consistent than implied in some contemporary versions of appraisal theory, or that there are problems with the validity of existing questionnaire-based measures of the variables in question. (shrink)

This article catalogs social processes contributing to construction of emotions across three time-scales, covering: natural selection; ontogenesis; and moment-by-moment transactions. During human evolution, genetic and cultural influences operate interdependently, not as separate forces working against each other. Further, leaving infants’ environment-open serves adaptive purposes. During ontogenesis, cultural socialization affects emotion development in various ways, not all of which depend on internalization of cultural meanings as emphasized in some earlier social constructionist accounts. Construction also operates over the moment-by-moment time-scale of real-time (...) interpersonal interactions, as emotions adjust to the constraints and affordances of immediate cultural environments. Claims that emotions are constructed, and that social processes contribute to their construction, are no longer contestable. Now the project is to specify how these processes operate and what materials they use. (shrink)

This paper distinguishes processes potentially contributing to interpersonal anxiety transfer, including object-directed social appraisal, empathic worry, and anxiety contagion, and reviews evidence for their operation. We argue that these anxiety-transfer processes may be exploited strategically when attempting to regulate relationship partners’ emotion. More generally, anxiety may serve as either a warning signal to other people about threat (alerting function) or an appeal for emotional support or practical help (comfort-seeking function). Tensions between these two interpersonal functions may account for mutually incongruent (...) interpersonal responses to expressed anxiety, including mistargeted interpersonal regulation attempts. Because worry waxes and wanes over time as a function of other people's ongoing reactions, interpersonal interventions may help to alleviate some of its maladaptive consequences. (shrink)

Drawing on research reviewed in this special section, the present article discusses how various contextual factors impact on production and decoding of emotion-related facial activity. Although emotion-related variables often contribute to activation of prototypical “emotion expressions” and perceivers can often infer emotional meanings from these facial configurations, neither process is invariant or direct. Many facial movements are directed towards or away from events in the shared environment, and their effects depend on these relational orientations. Facial activity is not only a (...) medium for descriptive representation of internal affective states, but also a means of adjusting to, and operating on, external objects, and of influencing other people’s appraisals of those objects. (shrink)

Does appraisal co-ordinate emotional responses? Are emotions usually reached via mental representations of relational meaning? This comment considers alternative causal routes in order to assess the centrality of appraisal in the explanation of emotion. Implicit and explicit meaning extraction can certainly help steer the course of emotion-related processes. However, presupposing that appraisals represent the driving force behind all aspects of emotion generation leads to inclusive formulations of appraisal or restrictive formulations of emotion.

People judge that an individual who attempts to harm someone but fails should be blamed and punished more when they imagine how things could have turned out worse, compared to when they imagine how things could have turned out the same, or when they think only about what happened. This moral counterfactual amplification effect occurs when people believe the protagonist had no reason for the attempt to harm, and not when the protagonist had a reason, as Experiment 1 shows. It (...) occurs for intentional failed attempts to harm and also for accidental near-misses, as Experiment 2 shows, but not for failed attempts in which the harm occurs anyway by another cause, for both general judgments about the event and specific judgments about the individual's actions, as Experiments 3 and 4 show. The implications for understanding the role of counterfactual thoughts in moral judgement are discussed. (shrink)

At first sight, the philosophy of Spinoza may seem wholly alien to what is now generally regarded as philosophy in the English-speaking world. For some decades, the dominant trend in that philosophy has been linguistic and anti-metaphysical; the philosopher is held to be concerned with the analysis of language, and not with speculative system-building. Spinoza, on the other hand, is very much a system-builder; as to the analysis of language, he says explicitly that this is of no interest to him. (...) ‘It is not my intention’, he says, ‘to explain the meanings of words; it is my intention to explain the nature of things’. However, the paper which follows will attempt to show that Spinoza’s philosophy is not wholly without relevance today. It will try to do this by placing one of Spinoza’s most important doctrines, his theory of human freedom, within the context of recent discussions. (shrink)

How do facial movements and verbal statements relate to emotional processes? A familiar answer is that the primary phenomenon is an internally located emotion that may then get expressed on the fac...

A social partner’s emotions communicate important information about their motives and intentions. However, people may discount emotional information that they believe their partner has regulated with the strategic intention of exerting social influence. Across two studies, we investigated interpersonal effects of communicated guilt and perceived strategic regulation in trust games. Results showed that communicated guilt mitigated negative effects of trust violations on interpersonal judgements and behaviour. Further, perceived strategic regulation reduced guilt’s positive effects. These findings suggest that people take emotion-regulation (...) motives into account when responding to emotion communication. (shrink)

To what extent does the level of overlap between social appraisal and social referencing depend upon the particular definitions adopted when following different research agendas? I argue that processes of both kinds fall under the more inclusive heading of relation alignment. Relation alignment also covers emotional influence that is not mediated by the communication of appraisal. Similarities, interdependences, and distinctions between these various relation-alignment processes warrant further investigation.

This paper argues against the thesis of Professor Savan, that Spinoza's views about words and about the imagination are such that he could not consistently say, and indeed did not think, that philosophical truths can be expressed adequately in language. The evidence for this thesis is examined in detail, and it is argued that Spinoza should have distinguished between two types of imagination, corresponding roughly to Kant's transcendental and empirical imagination. Finally, it is suggested that the bulk of the argument (...) of the Ethics is conducted on the level of the ?second kind of knowledge?, reason, but that it also contains examples of the use of the first and third kinds of knowledge. (shrink)

According to Brehm's intensity of emotion theory, if an emotion has motivational properties, its intensity should be non-monotonically affected by factors similar to those determining the intensity of motivational states. These factors are called deterrents. In the case of emotion, one category of deterrents consists of factors that can potentially interfere with feeling the emotion, such as reasons for not feeling the emotion. Two experiments were carried out to examine whether happiness is a motivational state and, thus, if its intensity (...) is non-monotonically determined by the importance of reasons for not feeling happy. We expected happiness to be reduced by a low importance reason for not feeling happy, to remain high in the presence of a moderately important reason, and to be reduced or eliminated by a very important reason. Both experiments supported the cubic function that results from these expectations, and when the results of the two studies were combined, each of the individual legs of the cubic function was found to be reliable along with the cubic function itself. The theoretical implications of these results are discussed. (shrink)

First published in 1993. Routledge is an imprint of Taylor & Francis, an informa company.

The Routledge History of Philosophy, Volume 4 covers a period of three hundred and fifty years, from the middle of the fourteenth century to the early years of the eighteenth century and the birth of modern philosophy. The focus of this volume is on Renaissance philosophy and seventeenth-century rationalism, particularly that of Descartes, Spinoza, and Leibniz. Science was ascendant during the Renaissance and beyond, and the Copernican revolution represented the philosophical climax of the middle ages. This volume is unique in (...) its emphasis on the relationship between science and philosophy. Placing the philosophy of the age into its scientific, social and cultural context, it examines the scholastic thought which Renaissance philosophy both interacted with and reacted against. A grasp of the intellectual context of the rationalists is also critical to an understanding of this philosophical movement, and the writings of Bacon, Gassendi, Hobbes, and others are analyzed here. The Routledge History of Philosophy, Volume 4 provides a broad, scholarly introduction to this period for students of philosophy and related disciplines, as well as some original interpretations of these authors. It will be important reading both for the specialist and the general reader. It includes a glossary of over one hundred technical terms and a chronological table of philosophical, scientific, and other cultural events. (shrink)