Beta‐oxidation of fatty acids and detoxification of reactive oxygen species are generally accepted as being fundamental functions of peroxisomes. Additionally, these pathways might have been the driving force favoring the selection of this compartment during eukaryotic evolution. Here we performed phylogenetic analyses of enzymes involved in beta‐oxidation of fatty acids in Bacteria, Eukaryota, and Archaea. These imply an alpha‐proteobacterial origin for three out of four enzymes. By integrating the enzymes' history into the contrasting models on the origin of eukaryotic cells, (...) we conclude that peroxisomes most likely evolved non‐symbiotically and subsequent to the acquisition of mitochondria in an archaeal host cell. (shrink)

At first glance the three eukaryotic protein translocation machineries – the ER‐associated degradation (ERAD) transport apparatus of the endoplasmic reticulum, the peroxisomal importomer and SELMA, the pre‐protein translocator of complex plastids – appear quite different. However, mechanistic comparisons and phylogenetic analyses presented here suggest that all three translocation machineries share a common ancestral origin, which highlights the recycling of pre‐existing components as an effective evolutionary driving force.Editor's suggested further reading in BioEssays ERAD ubiquitin ligases Abstract.

This book presents a timely reconfiguration of the relations between art, philosophy, ethics, and aesthetics. Through connection with a range of contemporary social and philosophical issues and movements, this collection of essays highlights the imperative of sensorial aesthetics. The book focuses on the radical philosophical approach to aesthetics enabled by the works of Jean-François Lyotard and Gilles Deleuze. From these philosophers an older meaning of aesthetic has been recalled. Before it indicated primarily the theory of art and beauty, “aesthetic” referred (...) to the sensibility, the capacity to receive sensations. In summoning this “sensorial” meaning of aesthetics in their respective works, Lyotard, Deleuze, and other recent thinkers turn the philosophical theory of aesthetics away from the dominance of cognitivist and reception theories, and towards a thinking of aesthetics through considerations of the movements of matter, affect, and sensation. (shrink)

Whether it is consciously focusing on a painting’s intricate layers of pigment or spontaneously being drawn to new layers of voices in a choral performance, attention appears essential to aesthetic experience. It is surprising, then, that the actual nature of attention is little discussed in aesthetic theory. Conversely, attention is currently one of the most vibrantly discussed topics in the philosophy of perception and in cognitive science. My aim is to demonstrate the need for and the value of aestheticians considering (...) such philosophical accounts in order to establish a clear understanding of ‘aesthetic attention’. I assess the existing aesthetic candidates against Wayne Wu’s characterization of attention as ‘selection for a task’. Finding that these candidates lack full explanatory force, I make the novel proposal that aesthetic attention is best characterized as ‘selecting for the sake of selection’. Finally, I suggest that both aesthetics and, more broadly, the philosophy of attention would benefit from paying aesthetic attention more attention. (shrink)

Hands are notoriously hard to draw. To compellingly capture their detail, proportion, and movement is generally considered a mark of an artist’s mastery of tech.

Carnal Knowledge is an outcome of the renewed energy and interest in moving beyond the discursive construction of reality to understand the relationship between what is conceived of as reality and materiality, described as the "material turn." It draws together established and emerging writers, whose research spans dance, music, film, fashion, design, photography, literature, painting and stereo-immersive VR, to demonstrate how art allows us to map the complex relations between nature and culture, between the body, language and knowledge. These writings (...) are unique in the field because they represent the authors' commitment to a new materialism through the creative arts. The questions they address include: Does the material turn in the creative arts take a different turn from continental epistemology, philosophy and the humanities? How does the agency of matter, the material nature of artistic practice and the notion of "truth to materials" affect what we understand as the "new materialism?" In engaging with these questions the book offers perspectives on the emergence of this exciting fresh field of new materialism. (shrink)

The objects we encounter in ordinary life and scientific practice - cars, trees, people, houses, molecules, galaxies, and the like - have long been a fruitful source of perplexity for metaphysicians. The Structure of Objects gives an original analysis of those material objects to which we take ourselves to be committed in our ordinary, scientifically informed discourse. Koslicki focuses on material objects in particular, or, as metaphysicians like to call them "concrete particulars", i.e., objects which occupy a single region of (...) space-time at each time at which they exist and which have a certain range of properties that go along with space-occupancy, such as weight, shape, color, texture, and temperature. The Structure of Objects focuses in particular on the question of how the parts of such objects, assuming that they have parts, are related to the wholes which they compose. (shrink)

'Wessen Wissen?' ist einerseits eine Frage nach Akteur-innen, Körpern, Materialien und Technologien, die in künstlerischen Produktions- und Wissensprozessen miteinander interagieren. Diese lassen sich als Übersetzungen und Transformationen beschreiben, in denen Künstler-nnen längst nicht mehr die einzigen Subjekte des Wissens sind. Denn in den künstlerischen Praktiken des Entwerfens, Skizzierens, Modellierens, Probens und Experimentierens entfalten Medien und Materialien ihre je eigene agentielle Kraft. 'Wessen Wissen?' ist andererseits eine Frage nach der Heterogenität von Wissensformationen in ihren partikularen und partialen Perspektiven, also nach situated (...) knowledges. Damit wird die Vorstellung einer allgemeingültigen, körperlosen, neutralen Objektivität bestritten. Im Gegenzug nimmt das situierte Wissen der Künste für sich in Anspruch, Erkenntnisse hervorzubringen und zur Verfügung zu stellen. Es steht demnach für verkörperte Kenntnisse, die in das Feld des zugelassenen und legitimen Wissens kritisch intervenieren. (shrink)

Wittgenstein und Merleau-Ponty gelten als Vertreter zweier gegensätzlicher Schulen, der Analytischen Philosophie und der Phänomenologie. In ihrer topologisch vergleichenden Analyse eröffnet Stengel an Hand der Situierung des Menschen im intersubjektiven Raum einen neuen Blick auf wesentliche Themen der modernen Philosophie, insbesondere die Probleme der Sprache und der Wahrnehmung. Der Vergleich der Wittgensteinschen Sprach- und der Merleau-Pontyschen Wahrnehmungsanalyse offenbart dabei verblüffende Ähnlichkeiten, die sich in einer Theorie des Schauens zusammenführen lassen. Das Buch revolutioniert die Debatte zwischen "Analytischer" und "Kontinentaler" Philosophie.

Some theories of linguistic meaning, such as those of Paul Grice and David Lewis, make appeal to higher–order thoughts: thoughts about thoughts. Because of this, such theories run the risk of being empirically refuted by the existence of speakers who lack, completely or to a high degree, the capacity of thinking about thoughts. Research on autism during the past 15 years provides strong evidence for the existence of such speakers. Some persons with autism have linguistic abilities that qualify them as (...) speakers, but manifest a severely impaired capacity to understand what it is to have beliefs. (shrink)

Implicit bias is one of the most successful cases in recent memory of an academic concept being translated into practice. Its use in the National Science Foundation ADVANCE program—which seeks to promote gender equality in STEM careers through institutional transformation—has raised fundamental questions about organizational change. How do advocates translate theories into practice? What makes some concepts more tractable than others? What happens to theories through this translation process? We explore these questions using the ADVANCE program as a case study. (...) Using an inductive, theory-building approach and combination of computational and qualitative methods, we investigate how the concept of implicit bias was translated into practice through the ADVANCE program and identify five key features that made implicit bias useful as a change framework in the academic STEM setting. We find that the concept of implicit bias works programmatically because it is demonstrable, relatable, versatile, actionable, and impartial. While enabling the concept’s diffusion, these characteristics also limit its scope. We reflect on implications for gender theories of organizational change and for practitioners. (shrink)

Normativism in the theory of meaning and content is the view that linguistic meaning and/or intentional content are essentially normative. As both normativity and its essentiality to meaning/content can be interpreted in a number of different ways, there is now a whole family of views laying claim to the slogan “meaning/content is normative”. In this essay, we discuss a number of central normativist theses, and we begin by identifying different versions of meaning normativism, presenting the arguments that have been put (...) forth for and against them. (shrink)

In public debate GMPs are oftenreferred to as being unnatural or a violationof nature. Some people have serious moralconcerns about departures from what is natural.Others are concerned about potential risks tothe environment arising from the combination ofhereditary material moving across naturalboundaries and the limits of scientificforesight of long-term consequences. To addresssome of these concerns we propose that anadditional element in risk assessment based onthe concept of familiarity should beintroduced. The objective is to facilitatetransparency about uncertainties inherent inthe risk assessment of (...) the GMP. Familiarityconventionally involves data and experiencerelating to the plant species and the ecosystemin question. We would like to extend thisconcept to the molecular level of plantbreeding and suggest that GMP characteristicsshould be compared to a reference baselinedetermined by conventional breeding techniques.Three GMPs are ranked according to familiarityat the plant and ecosystem level and themolecular level. The approach may help tointegrate discussion of the scientificarguments and moral questions raised in thedebate about GMOs by providing an operationalscheme within which moral concerns are broughtwithin the framework of science-based riskassessment. (shrink)

Roughly 80,000 U.S. prisoners are held in solitary confinement at any given time. A significant body of research shows that solitary confinement has severe, long-term effects, and the United Nations has condemned the practice of solitary confinement as torture. For years, prisoners have been organizing hunger strikes in order to protest solitary confinement. But such action is not without consequences, and some inmates have suffered serious injury or death. The question I raise in this paper is whether we ought to (...) force-feed hunger striking prisoners when serious harm is imminent. Both the World Medical Association and the American Medical Association have denounced the practice of force-feeding prisoners on hunger strike, and yet, the practice is common. Such prevalence is likely a result of the tension between the person-as-patient and person-as-prisoner and cannot easily be resolved. Instead, we must take seriously the complaint that solitary confinement is inhumane and avoid placing health professionals in the position where they must choose to force-feed the prisoner against his will or not. I argue that a conventional bioethics debate centering on polarizing principles of prisoner autonomy and a duty-to-protect the prisoner from harm is an inadequate framework for this complex issue. Instead, we must examine the prisoner’s intent and his right to freedom of speech. I argue that when the prisoner’s intent is to raise awareness and communicate with others, his hunger strike is a form of speech. Protest-as-speech is constitutionally protected—even for prisoners—and remains a minimum ethical obligation for society to uphold. (shrink)

In _Form, Matter, Substance_, Kathrin Koslicki defends a hylomorphic analysis of concrete particular objects (e.g., living organisms). The Aristotelian doctrine of hylomorphism holds that those entities that fall under it are compounds of matter (hulē) and form (morphē or eidos). Koslicki argues that a hylomorphic analysis of concrete particular objects is well-equipped to compete with alternative approaches when measured against a wide range of criteria of success. A successful application of the doctrine of hylomorphism to the special case of (...) concrete particular objects, however, hinges on how hylomorphists conceive of the matter composing a concrete particular object, its form, and the hylomorphic relations which hold between a matter-form compound, its matter and its form. Through the detailed answers to these questions Koslicki develops in this book, matter-form compounds, despite their metaphysical complexity, emerge as occupying the privileged ontological status traditionally associated with substances, due in particular to their high degree of unity. (shrink)

This inaugural lecture, delivered on 17 November 2021 at the University of Neuchâtel, addresses the question: Are material objects analyzable into more basic constituents and, if so, what are they? It might appear that this question is more appropriately settled by empirical means as utilized in the natural sciences. For example, we learn from physics and chemistry that water is composed of H2O-molecules and that hydrogen and oxygen atoms themselves are composed of smaller parts, such as protons, which are in (...) turn composed of yet smaller parts, such as quarks, and so on. While the question at the center of this lecture might thus appear to fall more appropriately into the empirical domain of natural science, I argue that metaphysics in fact has an important role to play in determining how best to answer the question before us. More concretely, I propose that the Aristotelian doctrine of hylomorphism, when appropriately interpreted, provides the best metaphysical answer to the question of whether and how material objects are analyzable into more basic constituents. Hylomorphism holds that those entities to which this doctrine applies are, in some sense, compounds of matter (“hylē”) and form (“morphē” or “eidos”). Thus, the title of this lecture, “Form, Matter, Substance”, refers to the claim that lies at the center of the doctrine of hylomorphism, as applied to the domain of material objects, namely that sensible substances are the result of combining matter and form in the right sort of way; or, for short, “form + matter = substance”. I begin in Section II by providing some historical background which brings out Aristotle’s motivations for proposing the doctrine of hylomorphism in the context of his analysis of change. Section III turns to some of the main features of the contemporary hylomorphic theory I have defended especially in Koslicki (2008) and Koslicki (2018). Section IV discusses some challenging questions concerning artifacts which arise for both hylomorphic and other approaches to the metaphysics of concrete particular objects. Section V concludes by summarizing why, as contemporary metaphysicians, we should prefer a hylomorphic theory over its competitors as an analysis of concrete particular objects that is compatible with our current scientific understanding of the world. (shrink)

Some theories of linguistic meaning, such as those of Paul Grice and David Lewis, make appeal to higher–order thoughts: thoughts about thoughts. Because of this, such theories run the risk of being empirically refuted by the existence of speakers who lack, completely or to a high degree, the capacity of thinking about thoughts. Research on autism during the past 15 years provides strong evidence for the existence of such speakers. Some persons with autism have linguistic abilities that qualify them as (...) speakers, but manifest a severely impaired capacity to understand what it is to have beliefs. (shrink)

A large body of research shows that emotionally significant stimuli are better stored in memory. One question that has received much less attention is how emotional memories are influenced by factors that influence memories after the initial encoding of stimuli. Intriguingly, several recent studies suggest that post-encoding factors do not differ in their effects on emotional and neutral memories. However, to date, only detrimental factors have been addressed. In the present study, we examined whether emotionally negative memories are differentially influenced (...) by a well-known beneficial factor: the testing of memories. We employed a standard cued recall testing-effect paradigm where participants studied cue-target pairs for negative and neutral target pictures. In a subsequent post-encoding phase, one third of the cue-target pairs were tested and one third restudied; the remaining third served as control pairs. After one week, memory for all cue-target pairs was tested. While replicating both the testing effect and the emotional enhancement effect, no differences between negative and neutral memories in the benefits received from testing and restudying were observed. Thus, it seems to be true that post-encoding factors do not influence emotional memories in any other way than neutral memories, even when they are beneficial. (shrink)

After many years of enduring the drought and famine of Quinean ontology and Carnapian meta-ontology, the notion of ground, with its distinctively philosophical flavor, finally promises to give metaphysicians something they can believe in again and around which they can rally: their very own metaphysical explanatory connection which apparently cannot be reduced to, or analyzed in terms of, other familiar idioms such as identity, modality, parthood, supervenience, realization, causation or counterfactual dependence. Often, phenomena such as the following are cited as (...) putative examples of grounding connections: systematic connections between entire realms of facts (mental/physical; moral/natural; etc.); truthmaking (e.g., the relation between the truth of the proposition that snow is white and snow’s being white); logical cases (e.g., the connection between conjunctive facts or disjunctive facts and their constituent facts); the determinate/determinable relation (e.g., the relation between something’s being maroon and its being red). I argue in this paper that classifying all of these phenomena as exhibiting grounding connections does not achieve much in the way of illumination. In fact, by treating a collection of phenomena which is in fact heterogeneous as though it were homogeneous, we have, if anything, taken a dialectical step backward. (shrink)

Rooftop gardens, rooftop greenhouses and indoor farms have been established or planned by activists and private companies in Berlin. These projects promise to produce a range of goods that could have positive impacts on the urban setting but also carry a number of risks and uncertainties. In this early innovation phase, the relevant stakeholders’ perceptions and social acceptance of ZFarming represent important preconditions for success or failure of the further diffusion of this practice. We used the framework of acceptance to (...) investigate the stakeholders’ attitudes and to identify the key factors that might hinder or promote the introduction of ZFarming. The results are based on an analysis of 38 qualitative interviews conducted with key stakeholders in Berlin. As the results show, major perceived benefits of ZFarming include improved consumer awareness, education, and the creation of experimental spaces. Stakeholders further perceive opportunities for resource savings, new business models, repurposing of abandoned buildings and improved aesthetics. Major perceived risks are associated with growing techniques that are considered “unnatural”, health risks, conflicts with images of traditional agriculture, the rejection of animal production in urban areas, the risk of projects being too expensive and too complex or being implemented too early, i.e. before the mechanisms are fully understood. The analysis further reveals which contextual factors—political, legal, market-related, spatial or societal—might negatively or positively influence ZFarming acceptance. (shrink)

This article suggests an assembly of ideas collected from transdisciplinary areas that in integration can potentially cast light on the role of affect and feeling in aesthetic experience. The article takes up a well-known philosophical quest to define the nature of aesthetic experience, but seeks out new territories of explanation that rest upon principles of rhetorical integration across a seemingly ambiguous landscape of separated theories, and under a dynamic, connective observatory perspective. The aim of the article is thus to suggest (...) a rhetorical design integrating results from the fields of neuroscience, biosemiotics, medical theory and philosophy of art, which could potentially result in an extension of traditional understandings of the roles of affect and feeling in processes of communication. I see the space of installation art, based on new technology and science, as a possible laboratory for the speculative mind, to which such investigations could be successfully related. I find that contemporary installation artworks can if successful induce an activation of processes intrinsic to the bodymind, which can bring forward new imaginations, new metaphors and extended self-understandings. (shrink)

Spekulation ist ein riskantes Unterfangen. Als Wette auf unverfügbare Zukünfte, kommende Gegenwarten oder alternative Vergangenheiten ist sie geprägt vom Nicht-Wissen, auf das sie sich ausrichtet und von dem sie ihren Ausgang nimmt. Im Unterschied zu Ökonomie und Zukunfts-forschung, die dem Nicht-Wissen mit Strategien des Risikomanagements begegnen, erforschen die Künste Möglichkeitsräume jenseits von gesicherter Erfahrung und prognostischem Wert. Sie sind dem Ungewissen verpflichtet? also dem, was man (noch) nicht wissen, über das man jedoch spekulieren kann. Im ästhetischen Spekulieren vermögen die Künste (...) gleichermassen plausible und widersprüchliche Szenarien zu testen, Heterochronien zu erproben und andere Körper zu denken. Der Band fragt, welches andere Wissen die spekulativen Verfahren der Kunst freilegen. Wie wird Künftiges, Virtuelles oder Utopisches vorstellbar? Und wie lassen sich vor diesem Hintergrund Kategorien wie künstlerische Produktion, ästhetische Erfahrung oder der Wert des Kunstwerks neu bestimmen? (shrink)

A significant reorientation is currently under way in analytic metaphysics, away from an almost exclusive focus on questions of existence and towards a greater concentration on questions concerning the dependence of one type of phenomenon on another. Surprisingly, despite the central role dependence has played in philosophy since its inception, interest in a systematic study of this concept has only recently surged among contemporary metaphysicians. In this paper, I focus on a promising account of ontological dependence in terms of a (...) non-modal and sufficiently constrained conception of essence developed by Kit Fine. I argue that even this essentialist account is, as it stands, not fine-grained enough to recognize different varieties of dependence which ought to be distinguished even within the realm of ontology. In some cases, an entity may be ontologically dependent on its essential constituents out of which it is constructed; but in other cases, an entity may be ontologically dependent on another for a different reason. A framework which glosses over these differences does not offer a proper diagnosis of why one entity ontologically depends on another. (shrink)

Essences have been assigned important but controversial explanatory roles in philosophical, scientific, and social theorizing. Is it possible for the same organism to be first a caterpillar and then a butterfly? Is it impossible for a human being to transform into an insect like Gregor Samsa does in Franz Kafka’s The Metamorphosis? Is it impossible for Lot’s wife to survive being turned into a pillar of salt? Traditionally, essences (or natures) have been thought to help answer such central questions about (...) existence, identity, persistence, and modality. These questions are not only of great philosophical interest, they also are of great interest to society at large. This Handbook surveys the state of the art on essence. Core issues about essence are discussed in 33 chapters, all of them written exclusively for this volume by leading experts. (shrink)

During the COVID-19 pandemic, students were facing great challenges. Learning was shifted from the classroom to the home of the students. This implied that students had to complete their tasks in a more autonomous way than during regular lessons. As students’ ability to handle such challenges might depend on certain cognitive and motivational prerequisites as well as individual learning conditions, the present study investigates students’ cognitive competencies as well as affective-motivational factors as possible predictors of coping with this new learning (...) situation at home. The study uses data of Starting Cohort 2 of the German National Educational Panel Study. Data of two measurement points are analyzed: Predictors were assessed at the earlier time point, when students mostly attended seventh grade of a secondary school. They completed competence tests in reading as well as mathematics and rated affective-motivational aspects in terms of willingness to exert effort, learning enjoyment, and intrinsic motivation. One and a half years later − during the COVID-19 pandemic and the first period of school closures − the second measurement point took place. Students’ parents rated the situation of learning at home with respect to students’ coping with the new situation and parents’ difficulties to motivate them. Regression analyses controlling for school track, students’ gender, and parents’ educational level and parental stress revealed that students’ reading competencies and their willingness to exert effort were significant predictors of their coping with the new learning situation at home. Moreover, parents reported that boys were more difficult to motivate to learn during this time as compared to girls. Other predictors turned out to be non-significant when entered simultaneously in the regression analyses. The results point to the importance of children’s prerequisites for autonomous learning situations without structuring elements by teachers within the school context. (shrink)

As meaning's claim to normativity has grown increasingly suspect the normativity thesis has shifted to mental content. In this paper, we distinguish two versions of content normativism: 'CE normativism', according to which it is essential to content that certain 'oughts' can be derived from it, and 'CD normativism', according to which content is determined by norms in the first place. We argue that neither type of normativism withstands scrutiny. CE normativism appeals to the fact that there is an essential connection (...) between content and correctness conditions. But, we argue, this fact is by itself normatively innocent, and attempts to add a normative dimension via the normativity of belief ultimately fail. CD normativism, in turn, falls prey to the 'dilemma of regress and idleness': the appeal to rules either leads to some form of regress of rules, or the notion of rule-following is reduced to an idle label. We conclude by suggesting that our arguments do not support naturalism: it is a mistake to assume that normativism and naturalism are our only options. (shrink)

The Assumption of Agency Theory Content Type Journal Article Category Review Pages 523-528 DOI 10.1558/jcr.v11i4.523 Authors Kathrine Elizabeth Anker, Planetary Collegium, Plymouth University, Drake Circus, Plymouth, Devon PL4 8AA, UK Journal Journal of Critical Realism Online ISSN 1572-5138 Print ISSN 1476-7430 Journal Volume Volume 11 Journal Issue Volume 11, Number 4 / 2012.

In cognitive research, metaphors have been shown to help us imagine complex, abstract, or invisible ideas, concepts, or emotions. Contributors to this book argue that metaphors occur not only in language, but in audio visual media well. This is all the more evident in entertainment media, which strategically "sell" their products by addressing their viewers’ immediate, reflexive understanding through pictures, sounds, and language. This volume applies cognitive metaphor theory to film, television, and video games in order to analyze the embodied (...) aesthetics and meanings of those moving images. (shrink)

This article discusses the potential of a contemporary understanding of what Heraclitus and the Stoics called ‘cosmological logos’, and its relation to human reason and cultural communication. I will relate the example of Descartes’ and his introspective method in Meditations on the First Philosophy (1647) to a contemporary understanding of the potential of introspection, related to theories of the embodied mind, virtual levels of nature and a possible connection between them. Where Descartes focused upon the rational properties of the logical (...) mind, and its potential to relate to nature’s higher logic, I relate my vision of a modern logos philosopher to Charles Sanders Peirce’s concept of nature’s ‘habits’, triad semiosis and the overall phaneroscopic phenomenology, which I connect to the concept of ‘aesthetic reason’. Aesthetic reason, in this context, represents a complex kind of rationality that involves a broader variety of cognitive processes. It is based on Extended Sentience, which includes properties of quantum communication that simultaneously work within the confinements of the mind–body, while simultaneously transgressing it. This article takes an overall evolutionary perspective, and claims that the prerequisites for experience and rationality are changing over historical time, due to evolutionary changes at endosemiotic levels of the mind–body. The prerequisites for Descartes’ activity of cognitive mediation and such of a modern logos philosopher, would thus not be equal. I will elaborate on the differences in this article. (shrink)

This paper argues for the digital interactive installation artwork based on principles of complexity as an interface with the potential to evoke ekspansions in the subjective experience by confronting the user with an idea of abstract thought, created through a conceptual design, and experienced through bodily interaction and contemplative acts at symbolic levels. The claim is, that ideas presented through good artworks based on the coalision of science and technology can potentially create a synthesis between ideas inspired by the philosophies (...) and empiricisms of the physical-material world view, but also of a higher, spiritual dimension, in which new possibilities of knowledge are potentially to be found. The article accepts the thesis of cognition being the cause of evolution, rather than evolution of man being the cause of cognition. (shrink)

It is widely acknowledged that surrealism has had a profound impact on postmodern philosophy. The skepticism that surrealism brought to bear on rationality and its revisionist influence on theories of the subject have been received in philosophical literature through writings such as those of Bataille or Artaud. However, current discourse has largely failed to recognize the wider influence surrealism has exerted on the theoretical study of the image. This essay aims to show the relevance of a surrealistic understanding of the (...) image for contemporary French philosophy, and to argue that it is most of all the substantial contribution surrealist painting has made in pointing up the obsessive character of the image that is in fact a major influence on the debate concerning the crisis of and in pictorial representation. (shrink)

The use of psychopharmaceuticals to enhance human mental functioning such as cognition and mood has raised a debate on questions regarding identity and authenticity. While some hold that psychopharmaceutical substances can help users to ‘become who they really are’ and thus strengthen their identity and authenticity, others believe that the substances will lead to inauthenticity, normalization, and socially-enforced adaptation of behaviour and personality. In light of this debate, we studied how persons who actually have experience with the use of psychopharmaceutical (...) medication would view their ‘self’ or their authentic personal identity in relation to the use of medication. We have interviewed a number of adults diagnosed with ADHD and discussed their experiences with medication use in relation to their conceptions of self and identity. In the first part of this paper we illustrate that the concepts of identity and authenticity play an important and sometimes problematic role in experiences of ADHD adults. This shows that the question about identity and psychopharmacology is not merely an ‘academic’ issue, but one that influences everyday lives of real people. In order to answer the question whether psychopharmaceuticals threaten personal identity and authenticity, more than empirical research is needed. We also need to analyse the concepts of personal identity, authenticity and self: what do we mean when we are using statements as ‘a way of living that is uniquely our own’, ‘our true self’, or ‘who we really are’? In the second part of this paper we discuss two important philosophical views on personal identity, authenticity and self: the self-control view as elaborated by Frankfurt, and the self-expression view as proposed by Schechtman. We compare these with the experiences of our respondents to see which view can help us to understand the diverse and often conflicting experiences that people have with medication for ADHD. This will contribute to a better understanding of whether and in which cases personal identity and authenticity are threatened by psychopharmacology. (shrink)

Barbara Bolt takes the most relevant of Heidegger's texts, including his most famous work, 'Being and Time', and sets out ways of thinking about art in a post-medium, digital, technocratic and post-human age.

Does the notion of ground, as it has recently been employed by metaphysicians, point to a single unified phenomenon? Jonathan Schaffer holds that the phenomenon of grounding exhibits the unity characteristic of a single genus. In defense of this hypothesis, Schaffer proposes to take seriously the analogy between causation and grounding. More specifically, Schaffer argues that both grounding and causation are best approached through a single formalism, viz., that utilized by structural equation models of causation. In this paper, I present (...) several concerns which suggest that the structural equation model does not transfer as smoothly from the case of causation to the case of grounding as Schaffer would have us believe. If it can in fact be shown that significant differences surface in how the formalism in question applies to the two types of phenomena in question, Schaffer’s attempt at establishing an analogy between grounding and causation has thereby been weakened and, as a result, the application of the Unity Hypothesis to the case of grounding once again stands in need of justification. (shrink)

This essay provides an opinionated survey of some recent developments in the literature on ontological dependence. Some of the most popular definitions of ontological dependence are formulated in modal terms; others in non-modal terms (e.g., in terms of the explanatory connective, ‘because’, or in terms of a non-modal conception of essence); some (viz., the existential construals of ontological dependence) emphasise requirements that must be met in order for an entity to exist; others (viz., the essentialist construals) focus on conditions that (...) must be satisfied in order for an entity to be the very entity it is at each time at which it exists; some are rigid, in the sense that they concern a relation between particular entities; others are generic, in the sense that they involve only a relation between an entity and some entities or other, which bear certain characteristics. I identify three potential measures of success with respect to which these different definitions of ontological dependence can be evaluated and consider the question of how well they in fact meet these desiderata. I end by noting that certain challenges face even the most promising essentialist construals of ontological dependence. (shrink)

Our knowledge of the human brain and the influence of pharmacological substances on human mental functioning is expanding. This creates new possibilities to enhance personality and character traits. Psychopharmacological enhancers, as well as other enhancement technologies, raise moral questions concerning the boundary between clinical therapy and enhancement, risks and safety, coercion and justice. Other moral questions include the meaning and value of identity and authenticity, the role of happiness for a good life, or the perceived threats to humanity. Identity and (...) authenticity are central in the debate on psychopharmacological enhancers. In this paper, I first describe the concerns at issue here as extensively propounded by Carl Elliott. Next, I address David DeGrazia’s theory, which holds that there are no fundamental identity-related and authenticity-related arguments against enhancement technologies. I argue, however, that DeGrazia’s line of reasoning does not succeed in settling these concerns. His conception of identity does not seem able to account for the importance we attach to personal identity in␣cases where personal identity is changed through enhancement technology. Moreover, his conception of authenticity does not explain the reason why we find inauthentic values objectionable. A broader approach to authenticity can make sense of concerns about changes in personal identity by means of enhancement technologies. (shrink)