In a 2003 Science article, Eric Juengst and colleagues asserted, “NIH [National Institutes of Health] has a responsibility to help society respond to the implications of antiaging research for whic...

This article examines democratic practice after the revolution that brought an end to authoritarian dictatorship in Portugal in April 1974, taking the Portuguese case as an opportunity to theorize democratic practice and historical processes that shape its emergence. The argument stresses the distinctive features of democracy born in social revolution and the explanatory role of the partial inversion of social hierarchies and remaking of cultural repertoires in social revolutionary settings. The Portuguese case is compared to its larger neighbor, Spain, which (...) moved from authoritarianism to democracy at roughly the same time following a process of change thoroughly unlike that of Portugal. Comparisons with other instances of postrevolutionary democracy and implications for more conventional democratic systems are also introduced. A central theme concerns the extent to which democracies attain the ideal of full political equality among citizens. This article asserts that democracies born in social revolution may approximate that ideal for reasons rooted in their historical pathways to representative government. (shrink)

Humanist sociologists are activists rooted in the reality of history and change and guided by a concern for the 'real life' problems of equality, peace, and social justice. They view people as active shapers of social life, capable of creating societies in which everyone's potential can unfold. Alfred McClung Lee introduces this volume with 'Sociology: Humanist and Scientific' and develops the theme that a sociology that is humanist is also scientific. The other nine selections are grouped into four parts: 'The (...) Individual and Social Life;' 'Social Institutions: Technology, Science, and Formal Organization;' 'Political Structures: Issues of Justice and Equality;' and 'Methodological Critiques and Counterproposals.'. (shrink)

This article shows how macro-historical processes of change can activate robust and enduring forms of citizenship practice, providing both survey-based evidence for this claim and a theorization of the causal mechanisms involved. Focusing on the case of Portugal, where democratization followed the historically unusual path of social revolution, we examine survey data on civic practice covering twenty countries and find Portugal to be a world leader in public participation in the electronic public sphere. When we examine the subsection of the (...) population socialized politically in the country’s post-revolutionary democracy, we find another important indicator of lively citizenship practice. The article takes the examination of this specific national case as the basis for developing an argument of broad theoretical relevance on the social underpinnings of lively and participatory citizenship practice. With an empirical foundation for our claims in survey data and other sources, our analysis of Portugal offers an interpretation of the case, leading to substantial revision of assumptions in the extant literature. More importantly, through our examination of this case, we show how large-scale macro-historical processes of change can encourage lively civic practice manifested at the individual level. Our argument highlights the importance of hierarchy-challenging collective experiences that reconfigure cultural frameworks and reorient the character of institutional practice. We take up the implications of this argument for cases lacking a history of revolution and find certain parallels with national cases shaped by movements of social reform as in the social democracies of Scandinavia. (shrink)

This handbook explores the link between ethnic identity and language from the perspectives of different social science disciplines and diverse geographical regions. This volume will serve as a complete resource on the subject and, because of its accessibility, will appeal to scholarly, college and lay audiences. "...a useful resource for readers who wish to gain an overview of some of the main issues of language and ethnicity in diverse regions and to understand the approach to these issues taken by scholars (...) in disciplines other than their own..."--Linguistics and Education. (shrink)

It is a near truism of philosophy of language that sentences are prior to words--that they are the only things that fundamentally have meaning. Robert's Stainton's study interrogates this idea, drawing on a wide body of evidence to argue that speakers can and do use mere words, not sentences, to communicate complex thoughts.

The current research investigates the interaction between thought suppression and individuals’ explicit awareness of their thoughts. Participants in three experiments attempted to suppress thoughts of a prior romantic relationship and their success at doing so was measured using a combination of self-catching and experience-sampling. In addition to thoughts that individuals spontaneously noticed, individuals were frequently caught engaging in thoughts of their previous partner at experience-sampling probes. Furthermore, probe-caught thoughts were: associated with stronger decoupling of attention from the environment, more likely (...) to occur under cognitive load, more frequent for individuals with a desire to reconcile, and associated with individual differences in the tendency to suppress thoughts. Together, these data suggest that individuals can lack meta-awareness that they have begun to think about a topic they are attempting to suppress, providing novel insight into the cognitive processes that are involved in attempting to control undesired mental states. (shrink)

The National Institute of Mental Health (Bethesda, MD) reports that approximately 5.2 million Americans experience post-traumatic stress disorder (PTSD) each year. PTSD can be severely debilitating and diminish quality of life for patients and those who care for them. Studies have indicated that propranolol, a beta-blocker, reduces consolidation of emotional memory. When administered immediately after a psychic trauma, it is efficacious as a prophylactic for PTSD. Use of such memory-altering drugs raises important ethical concerns, including some futuristic dystopias put forth (...) by the President's Council on Bioethics. We think that adequate informed consent should facilitate ethical research using propranolol and, if it proves efficacious, routine treatment. Clinical evidence from studies should certainly continue to evaluate realistic concerns about possible ill effects of diminishing memory. If memory-attenuating drugs prove effective, we believe that the most immediate social concern is the over-medicalization of bad memories, and its subsequent exploitation by the pharmaceutical industry. (shrink)

New pharmacological therapies, often dubbed `lifestyle drugs', demonstrate the enactment of yet another interface between technologies and bodies that promises a re-fashioning of the body with transformative, life-enhancing results. This article analyzes the emergence of one lifestyle drug, Viagra, from a technoscience studies perspective, conceptualizing Viagra as a new medical technology of the body. Through an analysis of promotional materials for Viagra, we argue that this pharmaceutical device performs ideological work through its discursive scripts that serves to reinforce and augment (...) dominant cultural narratives in relation to material bodies, particularly those of hegemonic masculinity and male (and female) sexuality. We conclude that Viagra carries the potential to reify and reinforce these dominant and hegemonic narratives, while at the same time, through ensuring an open market for heterogeneous users, it provides spaces for alternatives to these normative ideals and assumptions. (shrink)

_Education and Immigration_ comprises six reports that emerged from an EU funded comparative research project into the challenges posed to national education systems by immigration and its associated issues and problems. The immigration-related education policies and initiatives of six countries are explained, examined and compared. The book clearly delineates the historical, legal and sociological contexts of the various strategies, and how far these have been adhered to.

It has long been known that brain damage has important negative effects on one’s mental life and even eliminates one’s ability to have certain conscious experiences. It thus stands to reason that when all of one’s brain activity ceases upon death, consciousness is no longer possible and so neither is an afterlife. It seems clear that human consciousness is dependent upon functioning brains. This essay reviews some of the overall neurological evidence from brain damage studies and concludes that our argument (...) from brain damage has been vindicated by such overwhelming evidence. It also puts forth a more mature philosophical rationale against an afterlife and counters several replies to the argument. -/- 1. Philosophical Background -- 2. The Dependence of Consciousness on the Brain: Some Preliminary Evidence -- 3. Brain Damage, Lesion Studies, and the Localization of Mental Function - 3.1 Perception - 3.2 Awareness, Comprehension, and Recognition - 3.3 Memory - 3.4 Personality - 3.5 Language - 3.6 Emotion - 3.7 Decision-Making - 3.8 Social Cognition and Theory of Mind - 3.9 Moral Judgment and Empathy - 3.10 Neurological Disorders and Disease - 3.11 The Unity of Consciousness -- 4. Objections and Replies - 4.1 Souls, Minds, and Energy Fields - 4.2 The Instrument Theory - 4.3 The Embodied Soul Alone is Affected -- 5. Conclusion. (shrink)

His laboratory research focuses on the pathogenesis of infection in the immunocompromised host.

The density of states of a rectangular billiard with an Aharonov–Bohm flux line in its center was calculated in the semiclassical approximation and was used for the calculation of the form factor in the diagonal approximation. The distribution of nearest level spacings and the form factor were calculated also numerically. For some values of the flux these were found to be close to the ones of the semi-Poisson statistics. The difference between the numerical results and the semiclassical ones were found (...) to be much larger than for chaotic and for integrable systems within similar approximations. Possible reasons for these discrepancies are discussed. (shrink)

Neuronal growth and remodelling are guided by both intracellular gene programs and extracellular stimuli. The growth cone is one site where the effects of these extrinsic and intrinsic factors converge upon the mechanical determinants of cell shape. We review the growth cone as a transduction device, converting extracellular signals into mechanical forces. A variety of soluble, extracellular matrix and membrane bound molecules control growth cone behavior. In addition, GAP‐43 is discussed as a possible component of the Intraneuronal gene program which (...) modulates growth cone activity. The GTP‐binding protein, Go, is a major growth cone membrane protein that may transduce signals not only from outside the cell, but from within as well. This may provide a molecular site in the growth cone for the coordination of a genetic growth program with environmental signals. (shrink)

This book addresses three major questions about law and legal systems: (1) What are the defining and organizing forms of legal institutions, legal rules, interpretive methodologies, and other legal phenomena? (2) How does frontal and systematic focus on these forms advance understanding of such phenomena? (3) What credit should the functions of forms have when such phenomena serve policy and related purposes, rule of law values, and fundamental political values such as democracy, liberty, and justice? This is the first book (...) that seeks to offer general answers to these questions and thus gives form in the law its due. The answers not only provide articulate conversancy with the subject but also reveal insights into the nature of law itself, the oldest and foremost problem in legal theory and allied subjects. (shrink)

Professional sport in the United States has widely adopted biometric technologies, dramatically expanding the monitoring of players’ biodata. These technologies have the potential to prevent injuries, improve performance, and extend athletes’ careers; they also risk compromising players’ privacy and autonomy, the confidentiality of their data, and their careers. The use of these technologies in professional sport and the consumer sector remains largely unregulated and unexamined. We seek to provide guidance for their adoption by examining five areas of concern: validity and (...) interpretation of data; increased surveillance and threats to privacy; risks to confidentiality and concerns regarding data security; conflicts of interest; and coercion. Our analysis uses professional sport as a case study; however, these concerns extend to other domains where their use is expanding, including the consumer sector, collegiate and high school sport, the military, and commercial sectors where monitori... (shrink)

This special issue of Science, Technology, & Human Values assembles papers that consider relations among science, ethics, and justice. The papers are drawn from a 2011 National Science Foundation-sponsored workshop that brought together interdisciplinary scholars to consider, incorporate, and attend to the meanings, uses, and social consequences of ethical questions and justice ideals in technoscientific projects. The papers included in this special issue examine key areas that emerged from this workshop, including public participation, the production of knowledge, what counts as (...) consent, ownership of biomaterials, and others. Together, the papers raise questions about new directions and articulations of power, justice, and inequalities in science and technology studies. (shrink)

Philosophy is an exciting and accessible subject, and this engaging text acquaints students with the core problems of philosophy and the many ways in which they are and have been answered. Introducing Philosophy: A Text with Integrated Readings, Eighth Edition, insists both that philosophy is very much alive today and that it is deeply rooted in the past. Accordingly, it combines substantial original sources from significant works in the history of philosophy and current philosophy with detailed commentary and explanation that (...) help to clarify the readings. The selections range from the oldest known fragments to cutting-edge essays in feminism, multiculturalism, and cognitive science. At the end of each chapter is a summary, a list of review questions, a glossary, and a bibliography with suggestions for further reading. Important philosophical terms are carefully introduced in the text and also summarized at the end of each chapter, and brief biographies of the philosophers are provided at the end of the book. New to the Eighth Edition: Addressing the needs of a new generation of students, Robert C. Solomon has included for the first time more than 300 study and review questions. Appearing throughout the text and at the end of each chapter, these questions require immediate feedback from students. They encourage students to articulate the central ideas of what they have just read, instead of just "passing through" on the way to the next reading . New selections expand and update the chapters on religion, knowledge, mind and body, freedom, ethics, justice, and beauty. The selections include work by Charles Hartshorne, Cory Juhl, Friedrich Nietzsche, Jean-Paul Sartre, Sextus Empiricus, Edmund L. Gettier, David Braddon-Mitchell and Frank Jackson, Colin McGinn, Daniel Dennett, Harry Frankfurt, Gilbert Harman, Emma Goldman, and Arthur C. Danto. A companion website at www.oup.com/us/solomon8e features 300 study and review questions (100 multiple-choice, 100 true-or-false, and 100 fill-in-the-blank), discussion questions, chapter overviews and summaries, topical links, suggestions for further reading, and PowerPoint lecture aids. (shrink)

The purpose of this article is to provide a critical examination of two aspects of culture and biomedicine that have helped to shape the meaning and practice of genetic testing for breast cancer. These are: the cultural construction of fear of breast cancer, which has been fuelled in part by the predominance of a ‘risk’ paradigm in contemporary biomedicine. The increasing elaboration and delineation of risk factors and risk numbers are in part intended to help women to contend with their (...) fear of breast cancer. However, because there is no known cure or foolproof prevention for breast cancer, risk designations bring with them recommendations for vigilant surveillance strategies and screening guidelines. We argue that these in effect exacerbate women’s fears of breast cancer itself. The volatile combination of discourses of fear, risk and surveillance have significant ethical and social consequences for women’s lives and well-being. Genetic testing decisions are made within this context; if nurses understand this context they can play an important role in helping women to cope with the anxiety and fear of breast cancer risk. (shrink)

In this article, we suggest that the evidence regarding the social determinants of health calls for a deep re‐thinking of our understanding of distributive justice. Focusing on John Rawls's theory of distributive justice in particular, we argue that a full reckoning with the social determinants of health requires a re‐working of Rawls's principles of justice. We argue first that the social bases of health – a Rawlsian conception of the social determinants of health – should be considered a social primary (...) good. We argue second that including the social bases of health as a social primary good would lead the parties to the original position to choose an additional principle of justice and assign it lexical priority over Rawls's second principle. According to this principle, inequalities in people's share of the social bases of health are to be arranged so as to improve the health status of those least advantaged on the social health gradient. -/- . (shrink)

The National Institute of Mental Health reports that approximately 5.2 million Americans experience post-traumatic stress disorder each year. PTSD can be severely debilitating and diminish quality of life for patients and those who care for them. Studies have indicated that propranolol, a beta-blocker, reduces consolidation of emotional memory. When administered immediately after a psychic trauma, it is efficacious as a prophylactic for PTSD. Use of such memory-altering drugs raises important ethical concerns, including some futuristic dystopias put forth by the President's (...) Council on Bioethics. We think that adequate informed consent should facilitate ethical research using propranolol and, if it proves efficacious, routine treatment. Clinical evidence from studies should certainly continue to evaluate realistic concerns about possible ill effects of diminishing memory. If memory-attenuating drugs prove effective, we believe that the most immediate social concern is the over-medicalization of bad memories, and its subsequent exploitation by the pharmaceutical industry. (shrink)

A sourcebook for developing and facilitating collaborative groups capable of continuously adapting to anticipate the evolving learning needs of students. Based on a theoretical foundation of schools as complex systems in which linear management models are no longer sufficient.

Extraordinary extended lampbrush chromosomes with thousands of transcription loops are favorable objects in chromosome biology. Chromosomes become lampbrushy due to unusually high rate of transcription during oogenesis. However, until recently, the information on the spectrum of transcribed sequences as well as genomic context of individual chromomeres was mainly limited to tandemly repetitive elements. Here we briefly outline novel findings and future directions in lampbrush chromosome studies in the post‐genomic era. We emphasize the fruitfulness of combining genome‐wide approaches with microscopy imaging (...) techniques using lampbrush chromosomes as a remarkable model object. We believe that new data on the spectrum of sequences transcribed on the lateral loops of lampbrush chromosomes and their structural organization push the boundaries in the discussion of their biological role. Also see the video abstract here: https://youtu.be/zexoHfzX9rM. (shrink)

_Inspiring new techniques for engaging students with democratic ideals_ _John Dewey and the Philosophy and Practice of Hope_ combines philosophical theory with a study of its effects in an actual classroom. To understand how Dewey, one of the century's foremost philosophers of education, understood the concept of hope, Stephen Fishman begins with theoretical questions like: What is hope? What are its objects? How can hope foster a new understanding of democracy and social justice? The book's second half is a (...) classroom study that mir-rors in practice what Fishman explores in theory, as Lucille McCarthy observes Fishman's undergraduate students reading the theorists. Illustrating students' own vital engagement with the hope literature, McCarthy reveals how the discussions deepen student understandings, simultaneously showing education's power to promote hope and turn social ideals into reality. (shrink)

The purpose of this article is to provide a critical examination of two aspects of culture and biomedicine that have helped to shape the meaning and practice of genetic testing for breast cancer. These are: (1) the cultural construction of fear of breast cancer, which has been fuelled in part by (2) the predominance of a ‘risk’ paradigm in contemporary biomedicine. The increasing elaboration and delineation of risk factors and risk numbers are in part intended to help women to contend (...) with their fear of breast cancer. However, because there is no known cure or foolproof prevention for breast cancer, risk designations bring with them recommendations for vigilant surveillance strategies and screening guidelines. We argue that these in effect exacerbate women’s fears of breast cancer itself. The volatile combination of discourses of fear, risk and surveillance have significant ethical and social consequences for women’s lives and well-being. Genetic testing decisions are made within this context; if nurses understand this context they can play an important role in helping women to cope with the anxiety and fear of breast cancer risk. (shrink)

Develops a theory of culture based on a metaphysics that elaborates on the Platonic and Confucian traditions. In Metaphysics of Goodness, Robert Cummings Neville extends Alfred North Whitehead’s project of cultural studies, which was based on a new metaphysics that Whitehead developed in Adventures of Ideas. Neville’s focus is value or goodness in many modes. The metaphysics treated in this book derive from the Platonic and Confucian traditions, with significant modifications of Whitehead, Peirce, Dewey, Confucius, Xunzi, and Zhou Dunyi. (...) Part one develops a theory of form based on a metaphysics of harmony. Part two elaborates a theory of art based on a metaphysics of beauty. Part three sketches a theory of personhood based on a metaphysics of obligation. Part four discusses civilization in a systematic way based on a metaphysics of flourishing. Throughout the book, Neville elaborates a theory of interpretation that is inspired by Peirce, Dewey, and Xunzi but is not limited to their ideas. While the reasoning of the book is concise, it employs methodologies from many kinds of philosophy, art criticism, ethics, and cultural studies, and sees philosophy as needing to learn from all these disciplines. “Neville’s work is informed by a lifelong engagement with the most important philosophers in history, including Plato, Aristotle, Whitehead, and Dewey. Here, he offers an important argument that there is beauty not only in how people see the world, but also in the world itself.” — Kevin Schilbrack, Appalachian State University. (shrink)

In 1932, as America struggled to overcome the great economic depression and Hitler was taking power in Germany, Dewey issued a challenge to teachers. Based upon what he viewed as the principle by which to judge "the processes of education, formal and informal," he urged teachers to embrace the following goal: "Education should create an interest in all persons in furthering the general good, so that they will find their own happiness realized in what they can do to improve the (...) conditions of others" (LW 7: 243).In setting this challenge to teachers, Dewey has in mind helping students develop their character in two ways. First, teachers should nurture students' sensitivity to the impact of their speech and actions .. (shrink)

Robert Batterman examines a form of scientific reasoning called asymptotic reasoning, arguing that it has important consequences for our understanding of the scientific process as a whole. He maintains that asymptotic reasoning is essential for explaining what physicists call universal behavior. With clarity and rigor, he simplifies complex questions about universal behavior, demonstrating a profound understanding of the underlying structures that ground them. This book introduces a valuable new method that is certain to fill explanatory gaps across disciplines.

Schmidt’s game and other similar intersection games have played an important role in recent years in applications to number theory, dynamics, and Diophantine approximation theory. These games are real games, that is, games in which the players make moves from a complete separable metric space. The determinacy of these games trivially follows from the axiom of determinacy for real games, $\mathsf {AD}_{\mathbb R}$, which is a much stronger axiom than that asserting all integer games are determined, $\mathsf {AD}$. One of (...) our main results is a general theorem which under the hypothesis $\mathsf {AD}$ implies the determinacy of intersection games which have a property allowing strategies to be simplified. In particular, we show that Schmidt’s $(\alpha,\beta,\rho )$ game on $\mathbb R$ is determined from $\mathsf {AD}$ alone, but on $\mathbb R^n$ for $n \geq 3$ we show that $\mathsf {AD}$ does not imply the determinacy of this game. We then give an application of simple strategies and prove that the winning player in Schmidt’s $(\alpha, \beta, \rho )$ game on $\mathbb {R}$ has a winning positional strategy, without appealing to the axiom of choice. We also prove several other results specifically related to the determinacy of Schmidt’s game. These results highlight the obstacles in obtaining the determinacy of Schmidt’s game from $\mathsf {AD}$. (shrink)