The anvartha-saṃjñā compound associates two contradictory terms: anvartha, which means “[used] in conformity with his [etymological/first] meaning”, and saṃjñā which implies the idea of a convention; it therefore appears to be quite intriguing. The question is: is it relevant to focus on this contradiction or is it only a false problem? The aim of this paper is to answer the above question and this implies to grasp somewhat better the use of this notion by the Pāṇinian grammarians. To do so, (...) the author has studied the main texts of the Pāṇinian tradition, having in mind the following questions: did the Pāṇinian grammarians deal with this notion and, if so, in what terms? Did they perceive the contradiction raised by the association of the terms anvartha and samjñā? The study will show that this contradiction is only a false problem: according to the Pāṇinian grammarians quoted above, even when a saṃjñā is provided with an etymological/first meaning and its bearer (or one of its properties) is partly described by this meaning, this saṃjñā belongs, above all, to the domain of convention. (shrink)

The anvartha-saṃjñā compound associates two contradictory terms: anvartha, which means “[used] in conformity with his [etymological/first] meaning”, and saṃjñā which implies the idea of a convention; it therefore appears to be quite intriguing. The question is: is it relevant to focus on this contradiction or is it only a false problem? The aim of this paper is to answer the above question and this implies to grasp somewhat better the use of this notion by the Pāṇinian grammarians. To do so, (...) the author has studied the main texts of the Pāṇinian tradition, having in mind the following questions: did the Pāṇinian grammarians deal with this notion and, if so, in what terms? Did they perceive the contradiction raised by the association of the terms anvartha and samjñā? The study will show that this contradiction is only a false problem: according to the Pāṇinian grammarians quoted above, even when a saṃjñā is provided with an etymological/first meaning and its bearer (or one of its properties) is partly described by this meaning, this saṃjñā belongs, above all, to the domain of convention. (shrink)

The thymus is a unique primary lymphoid organ that supports the production of self‐tolerant T‐cells essential for adaptive immunity. Intrathymic microenvironments are microanatomically compartmentalised, forming defined cortical, and medullary regions each differentially supporting critical aspects of thymus‐dependent T‐cell maturation. Importantly, the specific functional properties of thymic cortical and medullary compartments are defined by highly specialised thymic epithelial cells (TEC). For example, in the medulla heterogenous medullary TEC (mTEC) contribute to the enforcement of central tolerance by supporting deletion of autoreactive T‐cell (...) clones, thereby counterbalancing the potential for random T‐cell receptor generation to contribute to autoimmune disease. Recent advances have further shed light on the pathways and mechanisms that control heterogeneous mTEC development and how differential mTEC functionality contributes to control self‐tolerant T‐cell development. Here we discuss recent findings in relation to mTEC development and highlight examples of how mTEC diversity contribute to thymus medulla function. (shrink)

Après avoir présenté l’institution récente de la kafâla, qui fut légalisée en Algérie en 1984 et au Maroc en 1993 en faveur des enfants abandonnés et en substitution au modèle prohibé de l’adoption, l’article propose une analyse des données recueillies lors d’une enquête ethnographique menée de 2005 à 2009. Elle révèle que l’enfant illégitime encourt davantage le risque d’être abandonné à la naissance s’il est de sexe masculin. En revanche, s’il est de sexe féminin, il bénéficie de plus de chances (...) de faire l’objet d’un don provisoire, direct et négocié, et surtout d’être adopté ou recueilli en kafâla suite à son abandon en institution. (shrink)

Un colloque international et pluridisciplinaire a rassemblé les 4, 5 et 6 octobre 2006 au Collège de France des anthropologues, juristes, historiens et philosophes spécialistes des questions de parenté. La rencontre, inscrite dans la continuité d’un précédent colloque consacré à l’alliance, portait cette fois sur « L’argument de la filiation, aux fondements des sociétés européennes et méditerranéennes anciennes et actuelles ». L’objectif premier des organisateurs était de construire un objet...

Although beef and dairy production in Alberta, Canada, enjoys strong public support, there are enduring public concerns, including farm animal welfare. Evolving codes of practice and animal care councils prescribe changes and improvements to many areas of farm management, and may be seen by farmers as an appropriate response to public animal welfare concerns. However, codes of practice do not address every animal welfare concern, and new concerns can arise over time. Drawing on social practice theory and in-depth field research (...) with 36 cattle and dairy farmers, this paper explores the materials, competencies, and meanings of four animal husbandry practices: branding, dehorning, weaning, and on-farm handling and moving. Findings show that branding and dehorning are evolving slowly with attention to pain management, but remain firmly rooted in ranching tradition and communities of practice. Weaning and animal handling practices are evolving more quickly with attention to changing materials, attitudes, and values that are more prevalent within producer communities. (shrink)

The idea that mythos and logos are incompatible, and that truth is a product of scientific and dialectical thinking, was certainly disproven by later Platonic philosophers. Deploying the works of Hesiod and Homer, Homeric Hymns and other such literature, they considered myth a valuable and significant augment to philosophical discourse. Plato’s denigration of myth gave his followers an incentive to read myth as allegory. The Stoics and first-century philosophers such as Philo, treated allegory as a legitimate interpretive strategy. The Middle (...) Platonists incorporated myth, for example, deifying the Monad and Dyad, as did 2nd century Platonists. Plutarch’s Isis and Osiris, for example, equates Isis and Osiris with form and matter: the god sows in matter logoi from himself. Porphyry’s allegorizing of Plato’s Cave of the Nymphs is another example. Plotinus is a strong influence on how the late Neoplatonists regarded myth. This paper argues that these philosophers’ use of allegory prepared the way for the Neoplatonists treatment of myth as inspired symbolism. Proclus and Syrianus, as reported by Hermias, did something more extreme by using mythology to construct inspired symbolic argument. Mythos becomes another type of logos, a vehicle for representing the invisible world of being, another kind of truth that can even serve a function in anagogic ascent. (shrink)

Many students have experienced the death of a loved one, which increases their risk of grief and mental health problems. Formal and social support can contribute to better coping skills and personal growth in bereaved students. The purpose of this study was to examine the support that students received or wanted to receive and its relation to students’ mental health. We also looked at students’ needs when receiving support and barriers in seeking formal and social support. Participants completed an online (...) survey consisting of questions about their sociodemographic characteristics, the support they received or wanted to receive, and support needs and barriers in seeking support. The survey also included three scales assessing grief, mental health distress, and personal growth. First, we analyzed the data descriptively. Next, we used MANCOVA to examine whether students who did or did not receive or wanted more support differed in terms of their grief, mental health distress, or personal growth. About 30% of students needed more support and experienced more grief and mental health distress than students who had their support needs met. Students who received support experienced more personal growth and grief than students who did not receive support. Students indicated a need for feeling acknowledged and safe. Feeling like a burden to others and perceiving their problems as not serious enough to warrant support were common barriers to seeking support. Our results indicate that support should be provided actively to students after the death of a loved one, and support being available on an ongoing basis. (shrink)

Omniprésent dans les médias, le terme transhumanisme nécessite un éclaircissement académique. En effet, il n'existe pas un, mais des transhumanismes. La parole est ici donnée à des penseurs de diverses disciplines, plus ou moins ouverts à ce courant d'idées parfois taxé d'idéologie, voire de menace pour l'Humanité. Ces craintes sont-elles fondées? Quelles sont les origines de ce mouvement de pensée? Quels en sont les différentes ramifications? Quelles en sont les réalisations, notamment dans le domaine médical? Un encadrement éthique et/ou juridique (...) de ces pratiques est- elle nécessaire? De nouveaux droits fondamentaux méritaient-ils d'être reconnus? La parole est ici donnée tant aux militants transhumanistes qu'aux penseurs critiques afin de croiser leurs regards"--Page 4 of cover. (shrink)

In this comment on Johan Von Essen’s contribution on the meaning of volunteering we make some remarks about Von Essen’s starting point, which reveals a particular perspective on meaningfulness, namely that people perceive reality as meaningful when their actions and the things they encounter are part of a meaningful whole. By introducing another perspective on meaningfulness, namely that the shattering of a meaningful whole is full of meaning, we question if practices of volunteering which occur in face-to-face situations—and thus outside (...) the public realm—can be fully captured by the five predicates that make up the phenomenological structure of volunteering. (shrink)

Cette note de recherche prend pour point de départ un certain nombre d’observations empiriques sur les pratiques d’écritures relatives à la « rédaction web ». Son ancrage est celui de l’analyse du discours, envisagée comme discipline interprétative et lecture critique des énoncés mais aussi comme démarche susceptible d’apporter sa contribution à une didactique de l’écrit. Nous y livrons quelques premiers éléments de réflexion pour la caractérisation discursive des textes issus de la rédaction web, prenant en compte pour cela à la (...) fois la composante discursive de ces productions et les discours construisant la rédaction web comme pratique d’écriture. A partir de deux exemples, nous montrons que les normes dominantes de la rédaction web, liées notamment aux contraintes du support et à des enjeux économiques, sont diversement prises en compte suivant la sphère d'activité où sont produits les textes. (shrink)

Marcella Althaus-Reid puts in print a discussion of sex, gender, and politics. For womanist theologian and ethicist, Townes, black women's experiences have been left out of the theoretical and material constructs of both black and feminist theologies in the United States. Townes argues that Althaus-Reid casts the reader in the role of voyeur as she describes the women lemon vendors in Indecent Theology. The reader observes them from the safety of their own cultural, economic, theo-ethical and sociopolitical mud huts in (...) the same way as the Europeans who queued to view the so-called'Hottentot Venus' in the early 1800s. Nevertheless, Althaus-Reid offers an integrated, interstructured analysis that helps pry open the dynamics of oppressions. (shrink)

In recent years, humans’ ability to selectively modify genes has increased dramatically as a result of the development of new, more efficient, and easier genetic modification technology. In this paper, we argue in favor of using this technology to improve the welfare of agricultural animals. We first argue that using animals genetically modified for improved welfare is preferable to the current status quo. Nevertheless, the strongest argument against pursuing gene editing for welfare is that there are alternative approaches to addressing (...) some of the challenges of modern agriculture that may offer ethical advantages over genetic modification; namely, a dramatic shift towards plant-based diets or the development of in vitro meat. Nevertheless, we provide reasons for thinking that despite these possible comparative disadvantages there are important reasons for continuing the pursuit of welfare improvements via genetic modification. (shrink)

Si les animaux d’élevage comme les animaux d’expérimentation intéressent depuis une trentaine d’années de plus en plus de personnes – de chercheurs, de militants –, les animaux dit de compagnie, en revanche, semblent toujours pâtir du préjugé selon lequel, parce qu’ils relèveraient d’une relation privée, ils seraient sans intérêt scientifique ou philosophique. Donna Haraway propose une façon tout à fait singulière de court-circuiter cet arrêt de la pensée afin de pouvoir re-problématiser cette relation à nouveau frais. Ce qui change immédiatement, (...) c’est le caractère non plus privé mais politique de cette co-relation : l’histoire biologique et politique qui nous unit à ces animaux dit de compagnie apparus massivement dans les années 1970 est toute aussi complexe que celle que nous partageons par ailleurs avec nos autres espèces compagnes. Comment raconter cette histoire et hériter des conséquences de cette co-évolution? Comment prendre au sérieux, moralement, politiquement nos relations inter-espèces? (shrink)

Puisque le changement social contribue à modifier et influencer le droit, l’objet de cette contribution est de comprendre de quelles manières ce dernier a des incidences sur le processus de formation du droit en prenant pour exemple la règle coutumière prohibitive de la détention arbitraire en droit international des migrations. Le but de cet article est de tenter de percevoir les effets des changements sociaux sur la coutume en prenant un exemple précis, tout en essayant d’émettre l’hypothèse que ce dernier (...) est révélateur de l’impact des changements sociaux sur la formation de la coutume internationale. En apportant dans un premier temps des éclairages utiles concernant le droit international des migrations, il s’agira dans un second temps d’apporter au lecteur des bases de compréhension essentielles sur la coutume internationale. Enfin, la troisième partie sera consacrée à expliciter des hypothèses qui pourraient expliquer d’une part de quelles manières des changements sociaux successifs ont influencé la formation de la règle coutumière de l’interdiction de la détention arbitraire et d’autre part, comprendre les raisons pour lesquelles les États acceptent d’être liés à cette règle. (shrink)

Acute starvation can have long-term consequences that are mediated through epigenetic change. Some of these changes are affected by the activity of AMP-activated protein kinase, a master regulator of cellular energy homeostasis. In Caenorhabditis elegans, the absence of AMPK during a period of starvation in an early larval stage results in developmental defects following their recovery on food, while many of them become sterile. Moreover, the loss of AMPK during this quiescent period results in transgenerational phenotypes that can become progressively (...) worse with each successive generation. Our recent data describe a chromatin-based mechanism of how AMPK mediates adjustment to acute starvation in the germ cells, however, the heritable aspect of this AMPK mutant phenotype remains unresolved. Here, we explore how AMPK might affect this process and speculate how the initial transcription that occurs in the germ cells may adversely affect subsequent germline gene expression and/or genomic integrity. AMPK protects germ cell integrity during acute starvation by blocking inappropriate transcription. How these aberrant transcripts cause transgenerational defects is unclear. AMPK likely regulates germline integrity at multiple levels through several targets. The authors speculate here how AMPK disruption during starvation could result in the observed defects seen at each generation. (shrink)

Dans son ouvrage La libération animale, Peter Singer développe trois grandes idées : le principe d'égale considération des intérêts, le rejet du spécisme et la nécessité de mettre un terme à certains types d'exploitation des animaux, notamment ceux qui ont trait à la recherche et à l'élevage industriel. Cette oeuvre phare a connu un retentissement immense, à tel point que sa publication, en 1975, a été présentée comme le moment clef dans l'émergence du mouvement éponyme. Cependant, le mouvement de libération (...) animale ne saurait se réduire à la seule pensée singerienne. Ce mouvement extrêmement protéiforme a fait l'objet de débats intenses à l'interne, entre les défenseurs des animaux eux-mêmes qui privilégient des approches diverses, comme à l'externe, entre ceux qui défendent le statu quo ou contestent les arguments animalistes. L'objet de ce recueil est de revenir sur le lien entre le mouvement de libération animale et les théories de Peter Singer qui, à tort ou à raison, en est perçu comme le père fondateur. Comment l'éthique animale de l'auteur a-t-elle été accueillie depuis la publication de La libération animale, et comment a-t-elle évolué? Quelle place la doctrine utilitariste occupe-t-elle dans le travail de Singer et dans les débats qu'il a engendrés? C'est en effet dans cette doctrine parente que résident les écueils auxquels s'est heurté le travail de l'auteur. C'est aussi là que son système a trouvé sa force et sa simplicité caractéristiques. C'est aussi, semble-t-il, ce qui fait la fécondité de ses idées. (shrink)

Cet article s’inscrit dans une réflexion sur le tournant que représente la philosophie politique moderne. Il a pour but de déconstruire la manière dont Michel Villey expose ce tournant : dans des cours professés entre 1961 et 1966 à la Faculté de droit de Paris, ce dernier extrapole, à la pensée juridique moderne, le mythe de l’« augustinisme politique », qui avait été forgé par Henri-Xavier Arquillière pour caractériser la source principale des doctrines théocratiques médiévales. Cette déconstruction montre que la (...) philosophie politique moderne provient certes d’un motif central de la Cité de Dieu, mais ce motif subit une double interprétation qui en modifie la signification : Luther accomplit le passage du motif spirituel des deux cités au problème théologico-politique des deux régimes, tandis que Hobbes fait entrer ce problème en philosophie sur la base des principes de la métaphysique classique. (shrink)

In this comment on Johan Von Essen’s contribution on the meaning of volunteering we make some remarks about Von Essen’s starting point, which reveals a particular perspective on meaningfulness, namely that people perceive reality as meaningful when their actions and the things they encounter are part of a meaningful whole. By introducing another perspective on meaningfulness, namely that the shattering of a meaningful whole is full of meaning, we question if practices of volunteering which occur in face-to-face situations—and thus outside (...) the public realm—can be fully captured by the five predicates that make up the phenomenological structure of volunteering. (shrink)

Fertility preservation has become more common for various populations, including oncology patients, transgender individuals, and women who are concerned about age-related infertility. Little attention has been paid to fertility preservation for patients with differences/disorders of sex development (DSD). Our goal in this article is to address specific ethical considerations that are unique to this patient population. To this end, we present a hypothetical DSD case. We then explore ethical considerations related to patient’s age, risk of cancer, concern about genetic transmission (...) of a DSD condition to children, co-occurring gender dysphoria, and access to experimental fertility preservation procedures. Given the limitations of current technologies, we recommend offering fertility preservation to individuals living with DSD using an informed decision-making approach that instills realistic expectations and minimizes the potential for false hope. Finally, we conclude with practical recommendations for this case based on the ethical considerations. (shrink)

Background: Autonomy is a central concept in both bioethics and rehabilitation. Bioethics has emphasized autonomy as self-governance and its application in treatment decision-making. In addition to discussing decisional autonomy, rehabilitation also focuses on autonomy as functional independence. In practice, responding to patients with diminished autonomy is an important component of rehabilitation care, but also gives rise to tensions and challenges. Our objective was to better understand the complex and distinctive ways that autonomy is understood and upheld in the context of (...) rehabilitation care by reviewing how autonomy is discussed in the rehabilitation literature. Methods: We conducted a scoping review addressing issues of autonomy in the context of mental and physical rehabilitation. Our process followed three sequential steps. We extracted and analyzed bibliometric information. We then examined how autonomy was defined and conceptualized. Finally, we examined how the articles discussed the roles of rehabilitation health professionals in responding to patient autonomy. Findings: The articles include 16 empirical reports, 17 case studies and 30 theoretical papers. The most common conceptual accounts of autonomy drew upon principlism, rights-based and legal analyses, and relational/social approaches. We identified four broad approaches for responding to patient autonomy: supporting, promoting, respecting and advocating. Conclusion: This review helps clarify some of the ambiguities and conceptual distinctions underlying discussions and practices related to autonomy in rehabilitation. It also draws attention to a wide range of activities that health professionals can undertake with the goal of supporting, promoting, respecting and advocating for patient autonomy in rehabilitation care. (shrink)

Background: Autonomy is a central concept in both bioethics and rehabilitation. Bioethics has emphasized autonomy as self-governance and its application in treatment decision-making. In addition to discussing decisional autonomy, rehabilitation also focuses on autonomy as functional independence. In practice, responding to patients with diminished autonomy is an important component of rehabilitation care, but also gives rise to tensions and challenges. Our objective was to better understand the complex and distinctive ways that autonomy is understood and upheld in the context of (...) rehabilitation care by reviewing how autonomy is discussed in the rehabilitation literature. Methods: We conducted a scoping review addressing issues of autonomy in the context of mental and physical rehabilitation. Our process followed three sequential steps. We extracted and analyzed bibliometric information. We then examined how autonomy was defined and conceptualized. Finally, we examined how the articles discussed the roles of rehabilitation health professionals in responding to patient autonomy. Findings: The articles include 16 empirical reports, 17 case studies and 30 theoretical papers. The most common conceptual accounts of autonomy drew upon principlism, rights-based and legal analyses, and relational/social approaches. We identified four broad approaches for responding to patient autonomy: supporting, promoting, respecting and advocating. Conclusion: This review helps clarify some of the ambiguities and conceptual distinctions underlying discussions and practices related to autonomy in rehabilitation. It also draws attention to a wide range of activities that health professionals can undertake with the goal of supporting, promoting, respecting and advocating for patient autonomy in rehabilitation care. (shrink)

Dans le cadre d’une analyse de discours professionnel, nous avons développé la notion de routine discursive pour décrire des séquences partiellement figées que l’on met en relation avec des déterminations textuelles et/ou discursives. Dans cet article nous nous intéressons à la façon dont ces routines s’inscrivent dans la textualité et contribuent à la façonner. Le principal résultat de nos explorations est la mise au jour d’une séquence que nous proposons d’appeler « séquence évaluative », dont nous dégageons les principaux traits. (...) Sur le plan méthodologique, nous avons procédé à des explorations textométriques autour des routines déjà identifiées et de formes qui peuvent jouer un rôle dans la structuration de la textualité de ces rapports : les marqueurs argumentatifs, les marqueurs de structuration textuelle et les formes de discours rapporté (RDA). Pour cela, nous avons procédé à une annotation multidimensionnelle du corpus grâce à l’outil d’annotation intégré dans Le Trameur.Nos analyses nous ont permis de dégager la présence récurrente d’un mouvement allant du général vers le particulier, qui est au principe d’une structuration en séquence dont nous dégageons les régularités. Notre travail met ainsi en évidence que l’activité d’évaluation propre au travail éducatif correspond à un processus rédactionnel qui repose sur la configuration textuelle des routines discursives. (shrink)

This paper draws on an in-depth phenomenological analysis of some interviews taken from volunteers, inviting them to reflect on their lived experiences of meaningfulness in the context of volunteering and citizenship. It is found that while some testimonies reinforce the standard conceptions of meaningfulness, other testimonies vary from it. The main challenge of this contribution consists in phenomenologically describing this alternative picture of meaningfulness, depicted as the event of witnessing. In a final part, the authors consider how volunteering is at (...) times especially prone to further experiences of witnessing. (shrink)

After reviewing the literature on current knowledge about consciousness in humans, we present a state-of-the art discussion on consciousness and related key concepts in animals. Obviously much fewer publications are available on non-human species than on humans, most of them relating to laboratory or wild animal species, and only few to livestock species. Human consciousness is by definition subjective and private. Animal consciousness is usually assessed through behavioural performance. Behaviour involves a wide array of cognitive processes that have to be (...) assessed separately using specific experimental protocols. Accordingly, several processes indicative of the presence of consciousness are discussed: perception and cognition, awareness of the bodily-self, self-related knowledge of the environment (including social environment). When available, specific examples are given in livestock species. Next, we review the existing evidence regarding neuronal correlates of consciousness, and emphasize the difficulty of linking aspects of consciousness to specific neural structures across the phyla because high-level cognitive abilities may have evolved independently along evolution. Several mammalian brain structures (cortex and midbrain) are involved in the manifestations of consciousness, while the equivalent functional structures for birds and fishes would likely be the pallium/tectum and midbrain. Caution is required before excluding consciousness in species not having the same brain structures as the mammalian ones as different neural architectures may mediate comparable processes. Finally, specific neurophysiological mechanisms appear to be strongly linked to the emergence of consciousness, namely neural synchrony and neural feedback. Considering the limited amount of data available and the few animal species studied so far, we conclude that different manifestations of consciousness can be observed in animals but that further refinement is still needed to characterize their level and content in each species. Further research is required to clarify these issues, especially in livestock species. (shrink)

Cet article propose un tour d’horizon de différents types de biais que l’on peut rencontrer dans les études basées sur l’annotation de corpus vidéo de langue des signes. En tâchant de situer objectivement les choix effectués et les biais potentiels à chaque étape, nous décrivons les méthodologies que nous avons mises en place dans trois études, portant respectivement sur la synchronisation des composantes corporelles, le mouvement des sourcils et les clignements des yeux, puis la coarticulation.