Research has shown that both physical exercise and cognitive training help to maintain cognition in older adults. The question is whether combined training might produce additive effects when the group comparisons are equated in terms of exercise intensity and modality. We conducted a systematic electronic search in MEDLINE, PsycInfo, and Cochrane Central Register of Controlled Trials databases to identify relevant studies published up to February 2021. Seven hundred and eighty-three effect sizes were obtained from 50 published intervention studies, involving 6,164 (...) healthy older adults, and submitted to a three-level meta-analysis. Results showed that combined training produced a small advantage in comparison to single cognitive training on executive functions, whereas both types of training achieved similar effects on attention, memory, language, processing speed, and global cognition. Combined training achieved higher training gains in balance than single physical training, indicating a transfer from cognitive training to balance. Performing cognitive and physical exercise simultaneously, and interactive training produced the largest gains in executive functions, speed, and global cognition, as well as the largest improvements in physical functions. Aerobic training was associated with higher effects in attention and fitness, whereas non-aerobic training produced larger effects in global cognition and balance. For all cognitive and physical outcomes, training resulted more advantageous when performed in a social context, even though individual training obtained similar results in balance as group training.Systematic Review Registration:www.crd.york.ac.uk/prospero/, identifier: CRD42020175632. (shrink)

The notion of memory storage, central to most contemporary theories of remembering, is challenged from a philosophical perspective as being contradictory and untenable. It criticizes this storage hypothesis as relying upon a linear explanation of time, an assumption which results in infinite regression, solipsism, and a failure to contact the real past. A model based on the phenomenological viewpoints of Edmund Husserl and Maurice Merleau-Ponty is offered as an alternative paradigm. Finally, a research method suggested by this descriptive approach to (...) memory is presented and illustrated. (shrink)

Very few scientists today question the fact that information, together with matter and energy, is one of the three constructs forming the ontology of the universe. However, there is still a long way to go before in order to establish the interrelations between information and energy and information and matter, as Einstein did between matter and energy. In this paper, after introducing the energy, matter, information model, which covers the three constructs and their relationships, we illustrate real examples—two qualitative and (...) two quantitative—of the interrelations between energy and information. This closes the open question with respect to the interrelationship between energy and information. (shrink)

One of the main challenges in medicine is to guarantee an appropriate drug supply according to the real needs of patients. Closed-loop strategies have been widely used to develop automatic solutions based on feedback variables. However, when the variable of interest cannot be directly measured or there is a lack of knowledge behind the process, it turns into a difficult issue to solve. In this research, a novel algorithm to approach this problem is presented. The main objective of this study (...) is to provide a new general algorithm capable of determining the influence of a certain clinical variable in the decision making process for drug supply and then defining an automatic system able to guide the process considering this information. Thus, this new technique will provide a way to validate a given physiological signal as a feedback variable for drug titration. In addition, the result of the algorithm in terms of fuzzy rules and membership functions will define a fuzzy-based decision system for the drug delivery process. The method proposed is based on a Fuzzy Inference System whose structure is obtained through a decision tree algorithm. A four-step methodology is then developed: data collection, preprocessing, Fuzzy Inference System generation, and the validation of results. To test this methodology, the analgesia control scenario was analysed. Specifically, the viability of the Analgesia Nociception Index as a guiding variable for the analgesic process during surgical interventions was studied. Real data was obtained from fifteen patients undergoing cholecystectomy surgery. (shrink)

Although sustainable and responsible investment (SRI) has quite recently become a hot research topic, scarcely any systematic research has been paid to the performance of this non-conventional approach to investment during the financial crisis that emerged in mid-2008 when the resilience of the financial markets was sorely tested. Such real-world resilience in practice is the subject of the current research which tests whether environmental, social and governance screens provides ethical investors with adaptive resilience in bull and bear market conditions by (...) focussing on the SRI equity index of one of the most active markets in Europe in terms of ethical investment, the FTSE4Good-Ibex in Spain. Multivariate Generalized Autoregressive Conditional Heteroskedasticity (M-GARCH) analysis indicates that ethical investors in the equity market examined with evidence that greater resilience in severe business cycle shocks could be attributable to SRI by companies. Although limited to a single country study, the results have implications for investors seeking resilience in crisis: when individual values and beliefs towards sustainability tie with personal investment strategy, the end result is adaptive financial resilience, social well-being and environmental defence. (shrink)

Automatic control of physiological variables is one of the most active areas in biomedical engineering. This paper is centered in the prediction of the analgesic variables evolution in patients undergoing surgery. The proposal is based on the use of hybrid intelligent modelling methods. The study considers the Analgesia Nociception Index to assess the pain in the patient and remifentanil as intravenous analgesic. The model proposed is able to make a one-step-ahead prediction of the remifentanil dose corresponding to the current state (...) of the patient. The input information is the previous remifentanil dose, the ANI variable and the electromyogram signal. Modelling techniques used are Artificial Neural Networks and Support Vector machines for Regression combined with clustering methods. Both training and validation were done with a real dataset from different patients. Results obtained show the potential of this methodology to calculate the drug dose corresponding to a given analgesic state of the patient. (shrink)

Literature and Character Education in Universities presents the potential of literary and philosophical texts for character education in modern universities. The book engages with theoretical and practical aspects of character development in higher education, combining conceptual discussion of the role of literature in character education with applied case studies from university classrooms. Character education within the academic context of the university presents unique challenges and opportunities. Literature and Character Education in Universities presents perspectives from academics in Europe, the USA and (...) Asia, offering unique insights into the ways that engaged reading and discussion of core texts can promote the development of intellectual and moral virtues. Chapters draw on a wide range of texts from Confucius' Analects to J. D. Salinger's The Catcher in the Rye, focusing on themes such as truthfulness, self-knowledge, prudence, tolerance, friendship, and humility. Literature and Character Education in Universities will be of real use to researchers, academics and postgraduates in the fields of higher education, philosophy, and literature. It should be essential reading for university educators interested in character development and advocates of literary education in modern universities. (shrink)

Closed-loop administration of propofol for the control of hypnosis in anesthesia has evidenced an outperformance when comparing it with manual administration in terms of drug consumption and post-operative recovery of patients. Unlike other systems, the success of this strategy lies on the availability of a feedback variable capable of quantifying the current hypnotic state of the patient. However, the appearance of anomalies during the anesthetic process may result in inaccurate actions of the automatic controller. These anomalies may come from the (...) monitors, the syringe pumps, the actions of the surgeon or even from alterations in patients. This could produce adverse side effects that can affect the patient postoperative and reduce the safety of the patient in the operating room. Then, the use of anomaly detection techniques plays a significant role to avoid this undesirable situations. This work assesses different one-class intelligent techniques to detect anomalies in patients undergoing general anesthesia. Due to the difficulty of obtaining real data from anomaly situations, artificial outliers are generated to check the performance of each classifier. The final model presents successful performance. (shrink)

The occurrence of oscillatory behaviours in living cells can be viewed as a visible consequence of stable, regulatory homeostatic cycles. Therefore, they may be used as experimental windows on the underlying physiological mechanisms. Recent studies show that growing pollen tubes are an excellent biological model for these purposes. They unite experimental simplicity with clear oscillatory patterns of both structural and temporal features, most being measurable during real‐time in live cells. There is evidence that these cellular oscillators involve an integrated input (...) of plasma membrane ion fluxes, and a cytosolic choreography of protons, calcium and, most likely, potassium and chloride. In turn, these can create positive feedback regulation loops that are able to generate and self‐sustain a number of spatial and temporal patterns. Other features, including cell wall assembly and rheology, turgor, and the cytoskeleton, play important roles and are targets or modulators of ion dynamics. Many of these features have similarities with other cell types, notably with apical‐growing cells. Pollen tubes may thus serve as a powerful model for exploring the basis of cell growth and morphogenesis. BioEssays 23:86–94, 2001. © 2001 John Wiley & Sons, Inc. (shrink)

In their article, “Immigrant legalization: A Dilemma Between Justice and The Rule of Law,” Sarah Song and Irene Bloemraad address rule of law objections to policies that would regularize the status of undocumented immigrants in the United States. On their view, justice requires that liberal democratic states (i.e., states that are committed to individual liberty and universal equality) provide pathways for undocumented immigrants to regularize their status. We do not disagree with Song and Bloemraad’s account: rule of law and regularization (...) policies are not inconsistent, and in fact regularization supports rule of law, when properly understood. Our view is that there needs to be a deeper investigation into the motivations of “rule of law” objections considered in Song and Bloemraad’s account. We argue that the real purpose of these objections is not necessarily to serve as an alternative to the justice-based claims of undocumented immigrants, but as a way to undermine them. On our account, these rule of law objections accomplish this undermining task through the mechanisms of dog whistling, discrediting and distorting, and ostracizing. (shrink)

Multi-Task Learning tries to improve the learning process of different tasks by solving them simultaneously. A popular Multi-Task Learning formulation for SVM is to combine common and task-specific parts. Other approaches rely on using a Graph Laplacian regularizer. Here we propose a combination of these two approaches that can be applied to L1, L2 and LS-SVMs. We also propose an algorithm to iteratively learn the graph adjacency matrix used in the Laplacian regularization. We test our proposal with synthetic and real (...) problems, both in regression and classification settings. When the task structure is present, we show that our model is able to detect it, which leads to better results, and we also show it to be competitive even when this structure is not present. (shrink)

There are many real-world applications like healthcare systems, job monitoring, well-being and personal fitness tracking, monitoring of elderly and frail people, assessment of rehabilitation and follow-up treatments, affording Fall Detection (FD) and ADL (Activity of Daily Living) identification, separately or even at a time. However, the two main drawbacks of these solutions are that most of the times, the devices deployed are obtrusive (devices worn on not quite common parts of the body like neck, waist and ankle) and the poor (...) battery life. Thus, this work proposes a low-power classification algorithm based on an Ensemble of KNN and K-Means algorithms (EKMeans) to identify Falls and High-Intensity ADL events such as running, jogging and climbing up stairs. The input of EKMeans are triaxial accelerometer data gathered from wrist-wearable devices. The proposal will be validated on the Fall&ADL publicly available datasets UMAFall, UCIFall and FallAllD, considering two kinds of activity labelling: Two-Class and Multi-Class. An exhaustive comparative study between our proposal, and the baseline algorithms KNN and a feed-forward Neural Network (NN) is deployed, where EKMeans outperformed clearly the Specificity (ADL classification) of the KNN and NN for the three datasets. Finally, a comparative battery consumption study has been included deploying the analyzed algorithms in a WearOS smartwatch, where EKMeans drains the battery from 100% to 0% in 27.45 hours, saving 5% and 21% concerning KNN and NN, respectively. Keywords: Human Activity Recognition, ADL Identification, Fall Detection TS Clustering, TS Classification, Wearable Devices, Low-Power HAR. (shrink)

Identity itself has become complex and fragmented in our age, and in this sense, perhaps conventional categories as cosmopolitanism therefore no longer suit us very well. Conceptualizing the intellectual landscape between reactionary localism and vapid universalism, is where the debate in ethical cosmopolitanism has landed today. Although it shows no real sign of theoretical resolving or slowing, cosmopolitan theory has taken more explicitly new direction connected with the project associated with Martha Nussbaum’s thought. I propose to deal in this paper (...) her ultimately and re-articulated cosmopolitan ideas. (shrink)

Hasta mediado s del siglo pasado, el tema que nos ocupa, la presencia de Cristo en los sacramentos, se resumía y concentraba, po r no deci r que se agotaba, en la presencia real eucanstica. O sea el concept o 'presencia' de Cristo se reservaba en la practica únicamente para su realización máxima en la Eucaristía; era la presencia real somática la que absorbía cualquier otra forma de presencia sacramental, que en todo caso quedaba en la sombra. Subrayo lo de (...) presencia sacramental, porque obviamente la presencia divina llenándolo todo, abarcando el cosmo s y la historia, no era desconocida Po r lo que a mi se m e alcanza, la primera vez que en un documento eclesiástico se hace explícita referencia a la presencia de Cristo en los sacramentos es precisamente en la única encíclica enteramente consagrada a la liturgia que hasta hoy conocemos : la Mediator Dei promulgada por Pío XII el 20 de noviembre de 1947. La doctrina aquí propuesta ha tenido tal aceptación o recepción que pertenece ya, podríamos decir, al tesoro de la Tradición. (shrink)

Etude de l'extension par la negation semi-intuitionniste de la logique positive des propositions appelee logique C, developpee par A. Urquhart afin de definir une semantique relationnelle valable pour la logique des valeurs infinies de Lukasiewicz (Lw). Evitant les axiomes de contraction et de reduction propres a la logique classique de Dummett, l'A. propose une semantique de type Routley-Meyer pour le systeme d'Urquhart (CI) en tant que celle-la ne fournit que des theories consistantes pour la completude de celui-ci.

The literature addressing bias and fairness in AI models (fair-AI) is growing at a fast pace, making it difficult for novel researchers and practitioners to have a bird’s-eye view picture of the field. In particular, many policy initiatives, standards, and best practices in fair-AI have been proposed for setting principles, procedures, and knowledge bases to guide and operationalize the management of bias and fairness. The first objective of this paper is to concisely survey the state-of-the-art of fair-AI methods and resources, (...) and the main policies on bias in AI, with the aim of providing such a bird’s-eye guidance for both researchers and practitioners. The second objective of the paper is to contribute to the policy advice and best practices state-of-the-art by leveraging from the results of the NoBIAS research project. We present and discuss a few relevant topics organized around the NoBIAS architecture, which is made up of a Legal Layer, focusing on the European Union context, and a Bias Management Layer, focusing on understanding, mitigating, and accounting for bias. (shrink)

In the graphical representation of ontologies, it is customary to use graph theory as the representational background. We claim here that the standard graph-based approach has a number of limitations. We focus here on a problem in the graph-based representation of ontologies in complex domains such as biomedical, engineering and manufacturing: lack of mereotopological representation. Based on such limitation, we proposed a diagrammatic way to represent an entity’s structure and various forms of mereotopological relationships between the entities.

The reductionist/anti-reductionist debate about testimonial justification (and knowledge) can be taken to collapse into a controversy about two kinds of underlying monitoring mechanism. The nature and structure of this mechanism remains an enigma in the debate. We suggest that the underlying monitoring mechanism amounts to emotion-based stereotyping. Our main argument in favor of the stereotype hypothesis about testimonial monitoring is that the underlying psychological mechanism responsible for testimonial monitoring has several conditions to satisfy. Each of these conditions is satisfied by (...) our “hot” stereotypical capacities. Intergroup emotions play a key role here. Intergroup emotions inform the agent about which candidate stereotype is better suited to the current situation. Emotions serve as evidence that makes a certain stereotype and its particular profile of features more or less expected. (shrink)

Business Ethics, the Environment & Responsibility, EarlyView.

Going from cognitive theory to neural data to ACT‐R models, the authors relate brain activity in a lexical ambiguity priming task to brain processes that resolve ambiguity in word meanings. These detailed data were tested and found compatible to the results of an ACT‐R computational model of reinforcement learning (RL). The model confirms and extends the behavioral findings to provide a RL account of individual differences in lexical ambiguity resolution.

For this issue of JBE, Zyphur and Pierides :1–16, 2017) have written a paper on a concept that they have labeled relational validity. The purpose of the paper and of their advocacy for the concept of relational validity is to improve the way that quantitative research is done by expanding our understanding of its ethics-laden aspects. I agree entirely with the authors that every decision regarding QR is an ethics-laden one and that our research as a whole would be improved (...) by recognition of this fact. I disagree with the authors regarding some of the ways that this improvement might be brought about. (shrink)

RESUMENUna de las líneas de investigación más interesantes de la actual filosofía de la psiquiatría gira en torno a la posibilidad de entender el contenido de los delirios a través de la noción wittgensteiniana de «certeza objetiva». En este artículo se mantiene que el contenido de los delirios se podría entender más fácilmente considerando la existencia de sistemas de creencias individuales y reformulando los conceptos diferenciales de dichos sistemas.PALABRAS CLAVEDELIRIO, CERTEZA OBJETIVA, CERTEZA SUBJETIVA, GRAMÁTICA, JUEGO DE LENGUAJEABSTRACTOne of the most (...) interesting research lines in recent philosophy of psychiatry deals with the possibility of understanding the content of delusions through Wittgenstein’s concept of «objective certainty». In this paper it is held that the content of delusions might be understood more easily by considering the existence of individual belief systems and reformulating the distinguishing concepts of such systems.KEYWORDSDELUSION, OBJECTIVE CERTAINTY, SUBJECTIVE CERTAINTY, GRAMMAR, LANGUAGE-GAME. (shrink)

RESUMENEl hombre moderno puede estar tentado a dar por supuesto que la diferencia entre razón y locura no fue creada en un momento dado; lejos de tal cosa, puede pensar que dicha diferencia constituye un hecho evidente, ya que será suficiente que contemple detenidamente a un loco para convencerse de que no tienen absolutamente nada en común. Sin embargo, este artículo no sólo explica en qué consiste el orden primitivo que el hombre moderno comparte con el loco, sino que además (...) ilustra las resistencias que el hombre moderno muestra al apreciar dicho orden.PALABRAS CLAVERazón, locura, orden, sociedad, voluntadABSTRACTThe modern man may be tempted to presuppose that the difference between reason and madness was not created in a certain moment; far from that, he may think that this difference constitutes an obvious fact as, just by looking carefully at a madman he may realize that they have absolutely nothing in common. However, this paper not only explains the nature of the primitive order the modern man shares with the madman, but also illustrates the resistance the modern man puts up when noticing this order.KEYWORDSReason, madness, order, society, will. (shrink)

Emotional intelligence stands at the nexus between intelligence and emotion disciplines, and we outline how EI research might be better integrated within both theoretical frameworks. From the former discipline, empirical research focused upon whether EI is an intelligence and what type of intelligence it constitutes. It is clear that ability-based tests of EI form a group factor of cognitive abilities that may be integrated into the Cattell–Horn–Carroll framework; less clear is the lower order factor structure of EI. From the latter (...) discipline, research linking EI with theoretical frameworks from emotion research remain relatively sparse. Emotion regulation and appraisal theory may be key to explain how EI may reflect different processes. We propose a research agenda to advance the EI study. (shrink)

Texto de la conferencia pronunciada en Estrasburgo el 19 de Noviembre de 1991, donde replanteándose ciertos aspectos recientes de la fortuna de Vico en España se aboga por la necesidad de establecer una fecunda reflexión a la vez sobre Vico y sobre nuestra propia historia.Text of conference of 19 November 1991 , where reconsidering certain aspects of the chance of Vico in Spain, the need to encourage a fruitful reflection of Vico and our own history is advocated.

La tecnología espacial y sus productos derivados se han convertido en un elemento fundamental para la vida y para la supervivencia y prosperidad de las sociedades desarrolladas y poseen un peso creciente en aquellas otras que están en vías de desarrollo. Esta dependencia del espacio irá, además, reforzándose progresivamente en los próximos años. Esta realidad, unida a los riesgos y desafíos asociados a fenómenos naturales, accidentes no provocados, o bien, a acciones intencionadas realizadas por otros actores en el espacio, trae (...) como consecuencia la necesidad de protección de nuestras actividades en el espacio para garantizar un acceso continuado; de no hacerlo, el impacto en el normal desarrollo de nuestras vidas y en el planeamiento y conducción de operaciones militares sería muy significativo. En general, las Fuerzas Armadas españolas disponen de un nivel muy aceptable de capacidades espaciales para afrontar los entornos operativos del presente. Sin embargo, el espacio ultraterrestre se encuentra cada vez más congestionado y disputado y, en este contexto, no existe la misma disponibilidad de capacidades necesarias para implementar un control efectivo del espacio que permita contrarrestar actividades maliciosas de potenciales adversarios, aspecto en el que resulta imprescindible avanzar. (shrink)

En un análisis de las relaciones de Vico con el cartesianismo, se plantea una perspectiva para la comprensión de su proyecto filosófico, enfocado a una dimensión práctica de la filosofía, a través de tres estrategias epistemológicas: dos de ellas en relación al criterio verum-factum y, una tercera, en relación con el principio verum-certum.Within the context defined by Vico’s relations with Cartesianim, a perspective oriented to the understanding of Vico’s philosophical project, casted on to a practical dimension of philosophy, is purported (...) as based on three main epistemological strategies: two of them related with the verum-factum criteron and a third one with the verum-certum principle. (shrink)

Aunque Vico hace varias referencias a Hobbes creemos que en realidad nunca tuvo un estrecho conocimiento del filósofo inglés. Pensamos que no merece la pena realmente buscar similitudes o coincidencias generales en textos seleccionados. Pero sí creemos que sería interesante comparar ambas actitudes metodológicas, su esfuerzo común por establecer las bases de una ciencia civil invirtiendo la "jerarquía de la evidencia", esto es, llevando el nivel de la ciencia social a las matemáticas y trasladando las ciencias naturales al rango de (...) la hipótesis.Although Vico makes several references to Hobbes, we are of the opinion that he never really had a narrow knowledge of the English philosopher. We do not think it worth to lock for similarities through some selected passages or some general coincidences. But we do think it interesting to compare both methodological attitudes, their common efforts to establish the bases of a civil science by reversing the "jerarchy of evidence", that is, by bringing the level of social science to that of mathematics and shifting the natural sciences to the rank of hypothesis. (shrink)

Each science has its own domain of investigation, but one and the same science can be formalized in different languages with different universes of discourse. The concept of the domain of a science and the concept of the universe of discourse of a formalization of a science are distinct, although they often coincide in extension. In order to analyse the presuppositions and implications of choices of domain and universe, this article discusses the treatment of omega arguments in three very different (...) formalizations of arithmetic. In Peano's formalization the domain is a restricted class of individuals, while the universe of discourse is the unrestricted class of all individuals. In Gödel's formalization the domain is a restricted class of individuals as in Peano's formalization, but the universe of discourse coincides with the domain. In Whitehead-Russell's formalization the domain is a class of logical notions in Tarski's sense, that are necessarily not individuals, whereas the universe of discourse is the unrestricted class of individuals as in Peano's formalization. The present approach emphasizes the viewpoint that the universe of discourse of a given discourse is important in determining which propositions are expressed by which sentences. (shrink)