Several lines of evidence suggest that children born via Cesarean section are at greater risk for adverse health outcomes including allergies, asthma and obesity. Vaginal seeding is a medical procedure in which infants born by C-section are swabbed immediately after birth with vaginal secretions from the mother. This procedure has been proposed as a way to transfer the mother's vaginal microbiome to the child, thereby restoring the natural exposure that occurs during vaginal birth that is interrupted in the case of (...) babies born via C-section. Preliminary evidence indicates partial restoration of microbes. However, there is insufficient evidence to determine the health benefits of the procedure. Several studies, including trial, are currently underway. At the same time, in the clinic setting, doctors are increasingly being asked to by expectant mothers to have their babies seeded. This article reports on the current research on this procedure and the issues it raises for regulators, researchers, physicians, and patients. (shrink)

Chapter Introduction The field of artificial intelligence is concerned with the construction of computer systems which exhibit intelligent behavior in order ...

Background Following passage of the Patient Self Determination Act in 1990, health care institutions that receive Medicare and Medicaid funding are required to inform patients of their right to make their health care preferences known through execution of a living will and/or to appoint a surrogate-decision maker. We evaluated the impact of external factors and perceived patient preferences on physicians’ decisions to honor or forgo previously established advance directives (ADs). In addition, physician views regarding legal risk, patients’ ability to comprehend (...) complexities involved with their care, and impact of medical costs related to end-of-life care decisions were explored. Methods Attendees of two Mayo Clinic continuing medical education courses were surveyed. Three scenarios based in part on previously court-litigated matters assessed impact of external factors and perceived patient preferences on physician compliance with patient-articulated wishes regarding resuscitation. General questions measured respondents’ perception of legal risk, concerns over patient knowledge of idiosyncrasies involved with their care, and impact medical costs may have on compliance with patient preferences. Responses indicating strength of agreement or disagreement with statements were treated as ordinal data and analyzed using the Cochran Armitage trend test. Results Three hundred eighty-eight of 951 surveys were completed (41% response rate). Eighty percent reported they were likely to honor a patient’s AD despite its 5 year age. Fewer than half (41%) would honor the AD of a patient in ventricular fibrillation who had expressed a desire to “pass away in peace.” Few (17%) would forgo an AD following a family’s request for continued resuscitative treatment. A majority (52%) considered risk of liability to be lower when maintaining someone alive against their wishes than mistakenly failing to provide resuscitative efforts. A large percentage (74%) disagreed that patients could not appreciate complexities surrounding their care while 69% agreed that costs should never impact a physician’s decision as to whether to comply with a patient’s AD. Conclusions Our findings highlight the impact, albeit small, external factors have on physician AD compliance. Most respondents based their decision on the clinical situation at hand and interpretation of the patient’s initial wishes and preferences expressed by the AD. (shrink)

One problem of interpreting research on subconscious processing is the possibility that participants are weakly conscious of the stimuli. Here, we compared the fMRI BOLD response in healthy adults to clearly visible single letters with the response to letters presented in the absence of any behavioural evidence of visibility . No letter catch trials served as a control condition. Forced-choice responses did not differ from chance when letter-to-background contrast was low, whereas they were almost 100% correct when contrast was high. (...) A comparison of fMRI BOLD signals for supraliminal and subliminal letters with the control trials revealed a signal increase in left BA 37 . Comparison of supraliminal with subliminal letters showed a significant increase in the right inferior frontal gyrus . Finally, a comparison of subliminal with supraliminal letters showed increases in the left middle temporal gyrus and the right extrastriate cortex. (shrink)

This article analyzes whether Brandom’s ISA (inferential-substitutional-anaphoric) semantics as presented in Making It Explicit (MIE) and Articulating Reasons (AR) can cope with problems resulting from inferentialism’s near-implied meaning holism. Inferentialism and meaning holism entail a radically perspectival conception of content as significance for an individual speaker. Since thereby its basis is fixed as idiolects, holistic inferentialism engenders a communication-problem. Brandom considers the systematic difference in information among individuals as the „point“ of communication and thus doesn’t want to diminish these effects (...) of inferentialism. Instead, explains communication with a model of “navigating among perspectives without sharing contents”. The crucial element in this navigation-model is the functioning of anaphoric connections between tokens uttered in discourse that can be used by every individual speaker in their own perspectival semantic substitution-economies. The heart of Brandom’s semantics is the thesis of the purely inferential, hence non-referential nature of anaphora, coupled with the claim that anaphoric-inferential semantic mechanisms yield sufficient conditions for mutually successful “information-extraction” or interpretation. This article disputes the thesis and denies the claim. Regarding the former it is observed that all of Brandom’s plausible reconstructions of anaphoric discourse-structures rely on covert “reference-infiltrations” that can’t be eliminated. Regarding the latter, a new argument based on context-sensitive semantic phenomena in anaphoric settings shows that the crucial distinction between initiator or anaphoric antecedent and anaphoric dependent cannot be drawn according to Brandom’s own premises without overt and irreducible referential premises. The article concludes that either Brandom’s semantics can offer determinate contents, but then must accept genuinely referential semantic primitives, or else it leaves utterance-contents undeterminable and hence cannot explain communication. (shrink)

Quine claims that holism (i.e., the Quine-Duhem thesis) prevents us from defining synonymy and analyticity (section 2). In Word and Object, he dismisses a notion of synonymy which works well even if holism is true. The notion goes back to a proposal from Grice and Strawson and runs thus: R and S are synonymous iff for all sentences T we have that the logical conjunction of R and T is stimulus-synonymous to that of S and T. Whereas Grice and Strawson (...) did not attempt to defend this definition, I try to show that it indeed gives us a satisfactory account of synonymy. Contrary to Quine, the notion is tighter than stimulus-synonymy – particularly when applied to sentences with less than critical semantic mass (section 3). Now according to Quine, analyticity could be defined in terms of synonymy, if synonymy were to make sense: A sentence is analytic iff synonymous to self-conditionals. This leads us to the following notion of analyticity: S is analytic iff, for all sentences T, the logical conjunction of S and T is stimulus-synonymous to T; an analytic sentence does not change the semantic mass of any theory to which it may be conjoined (section 4). This notion is tighter than Quine's stimulus-analyticity; unlike stimulus-analyticity, it does not apply to those sentences from the very center of our theories which can be assented to come what may, even though they are not synthetic in the intuitive sense (section 5). Conclusion: We can have well-defined notions of synonymy and analyticity even if we embrace Quine's holism, naturalism, behaviorism, and radical translation. Quine's meaning skepticism is to be repudiated on Quinean grounds. (shrink)

In his critical study of Speusippus Leonardo Tarán (T.) expounds an interpretation of a considerable part of the controversial books M and N of Aristotle's Metaphysics. In this essay I want to consider three aspects of the interpretation, the account of Plato's ‘ideal numbers’ (section I), the account of Speusippus’ mathematical ontology (section II), and the account of the principles of that ontology (section III). T. builds his interpretation squarely on the work of Harold Cherniss (C.), to whom I will (...) also refer. I concentrate on T. because he has brought the ideas in which I am interested together and given them a concise formulation; he is also meticulous in indicating the secondary sources with which he agrees or disagrees, so that anyone interested in pursuing particular points can do so easily by consulting his book. (shrink)

BackgroundStory recall tests have shown variable sensitivity to rate of cognitive decline in individuals with Alzheimer’s disease biomarkers. Although SR tasks are typically scored by obtaining a sum of items recalled, item-level analyses may provide additional sensitivity to change and AD processes. Here, we examined the difficulty and discrimination indices of each item from the Logical Memory SR task, and determined if these metrics differed by recall conditions, story version, lexical categories, serial position, and amyloid status.Methodsn = 1,141 participants from (...) the Wisconsin Registry for Alzheimer’s Prevention longitudinal study who had item-level data were included in these analyses, as well as a subset of n = 338 who also had amyloid positron emission tomography imaging. LM data were categorized into four lexical categories, and by serial position. We calculated difficulty and discriminability/memorability by item, category, and serial position and ran separate repeated measures ANOVAs for each recall condition, lexical category, and serial position. For the subset with amyloid imaging, we used a two-sample t-test to examine whether amyloid positive and amyloid negative groups differed in difficulty or discrimination for the same summary metrics.ResultsIn the larger sample, items were more difficult in the delayed recall condition across both story A and story B. Item discrimination was higher at delayed than immediate recall, and proper names had better discrimination than any of the other lexical categories or serial position groups. In the subsample with amyloid PET imaging, proper names were more difficult for Aβ+ than Aβ−; items in the verb and “other” lexical categories and all serial positions from delayed recall were more discriminate for the Aβ+ group compared to the Aβ− group.ConclusionThis study provides empirical evidence that both LM stories are effective at discriminating ability levels and amyloid status, and that individual items vary in difficulty and discrimination by amyloid status, while total scores do not. These results can be informative for the future development of sensitive tasks or composite scores for early detection of cognitive decline. (shrink)

Background: Magnetic resonance spectroscopic imaging is a neuroimaging technique that may be useful for non-invasive mapping of brain temperature over a large brain volume. To date, intra-subject reproducibility of MRSI-based brain temperature has not been investigated. The objective of this repeated measures MRSI-t study was to establish intra-subject reproducibility and repeatability of brain temperature, as well as typical brain temperature range.Methods: Healthy participants aged 23–46 years were scanned at two time points ~12-weeks apart. Volumetric MRSI data were processed by reconstructing (...) metabolite and water images using parametric spectral analysis. Brain temperature was derived using the frequency difference between water and creatine for 47 regions of interest delineated by the modified Automated Anatomical Labeling atlas. Reproducibility was measured using the coefficient of variation for repeated measures, and repeatability was determined using the standard error of measurement. For each region, the upper and lower bounds of Minimal Detectable Change were established to characterize the typical range of TCRE values.Results: The mean global brain temperature over all subjects was 37.2°C with spatial variations across ROIs. There was a significant main effect for time [F = 37.0, p < 0.0001] and for brain region [F = 2.66, p < 0.0001]. The time*brain region interaction was not significant [F = 0.80, p = 0.83]. Participants' TCRE was stable for each ROI across both time points, with ROIs' COVrep ranging from 0.81 to 3.08% ; majority of ROIs had a COVrep <2.0%.Conclusions: Brain temperature measurements were highly consistent between both time points, indicating high reproducibility and repeatability of MRSI-t. MRSI-t may be a promising diagnostic, prognostic, and therapeutic tool for non-invasively monitoring brain temperature changes in health and disease. However, further studies of healthy participants with larger sample size and numerous repeated acquisitions are imperative for establishing a reference range of typical brain TCRE, as well as the threshold above which TCRE is likely pathological. (shrink)

Experiments are presented showing that visual search for Mueller-Lyer (ML) stimuli is based on complete configurations, rather than component segments. Segments easily detected in isolation were difficult to detect when embedded in a configuration, indicating preemption by low-level groups. This preemption—which caused stimulus components to become inaccessible to rapid search—was an all-or-nothing effect, and so could serve as a powerful test of grouping. It is shown that these effects are unlikely to be due to blurring by simple spatial filters at (...) early visual levels. It is proposed instead that they are due to more sophisticated processes that rapidly bind contour fragments into spatially-extended assemblies. These results support the view that rapid visual search cannot access the primitives formed at the earliest stages of visual processing; rather, it can access only higher-level, more ecologically-relevant structures. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:The Victorian Translation of China: James Legge's Oriental PilgrimageRoger CorlessThe Victorian Translation of China: James Legge's Oriental Pilgrimage. By Norman J.Girardot. Berkeley, Los Angeles, London: University of California Press, 2002. xxx + 780 pp.Don't make the mistake I made and allow the size of this book intimidate you. I let it sit around for many months, fearing, as did the author, to "[row] out over the great ocean (...) of material" (pp. xix-xx), but once I had set sail I found myself in enjoyable, if sometimes irascible, company and I was unwilling to jump ship. Girardot is in full command of his ark of fascinating and diverse creatures, and his main argument is never lost in the details. His writing is lucid and the text is broken up into manageable blocks by subheadings with intriguing titles, rendering each segment ehipassiko, encouraging us to keep reading.A book of this importance and weight (about 1.5 kg) deserves a review article more than just a review, or, better, a discussion panel at a major academic conference. This journal is notorious for reviews of astonishing length, but I would like my review to be short enough that it will actually be read, so that it will entice you to read the book. I will not attempt a summary nor will I critically address all the issues that are brought up. Instead, I will try to show why I regard this book as an instant classic and even, I would say, a watershed in the meta-science of sinological and Religionswissenschaftlich self-reflection.We all know James Legge as the perpetrator of The Chinese Classics, the multivolume opus that, in the 1960 Hong Kong University Press revision, dominates the Chinese religion(s) section of our personal libraries. Since there is nothing like it, we consult it, but we pretend we do not, for, after all, it's out of date, surely, and Legge was an old fuddy-duddy—Scottish, a Protestant missionary, and, worst of all, a Victorian. Girardot seems to have had somewhat this opinion of Legge when he assayed a brief biography of him, but he discovered that his "Legge work" (as he calls it) opened the door to a pivotal era in academe and world culture. Once the door to the long-neglected cupboard had been opened, all kinds of fascinating objects came tumbling out. "Oh, so that's how it used to be, and that's why it's like this today!" No scholar of Chinese religion(s) can afford to ignore Girardot's extensive and insightful ruminations on the state of the field then and now.The point of the book is summed up on page 531: "[Legge] is an outstanding [End Page 276] example of the difficult nineteenth-century passage from religious discourse to what Edward Said calls the 'secular criticism' of the modern world." To study Legge is to study the origins of our discipline. He may have been a fuddy-duddy; he was certainly a workaholic, putting his Sassenach colleagues at Oxford to shame by sleeping little and rising in the middle of the night to persist in his hermeneutic labors. But he was also a student of the heathen land he went to convert, and he tried his best not only to see (the presumed universal) God in the ancient texts but also to find something noble in apparent atheists and agnostics such as Confucius. In his interaction with Max Mueller (and this book is as much about Mueller as it is about Legge) he both agreed and disagreed, in a complex choreography, with the comparative method underpinning The Sacred Books of the East. He was a Scotsman's Scotsman, a stag at bay, dourly standing his ground (as a Congregationalist, and therefore a nonconformist both north and south of the border) against, first, the London Missionary Society and, later, the prevailing academic and ecclesiastical climate at Oxford.No armchair orientalist, as were some of his colleagues across the Channel, he befriended native informants and studied the indigenous commentaries (mostly Qing) to which they referred him, so that his translations, although not as fluid as Waley... (shrink)

Introduction to sensory psychology, by C. Mueller.--Some reflections on brain and mind, by R. Brain.--In search of the engram, by K. Lashly.--Cerebral organization and behavior, by R. W. Sperry.--Relations between the central nervous system and the peripheral organs, by E. von Holst.--Effects of the Gestalt revolution, by J. E. Hochberg.--Seeing in depth, by R. L. Gregory.--The stimulus variables for visual depth perception, by J. J. Gibson.--The elaboration of the universe, by J. Piaget.--Visual perception approached by the method of stabilized images, (...) by R. M. Pritchard, W. Heron, and D. O. Hebb.--Philosophy as rigorous science, by E. Husserl.--The "sensation" as a unit of experience, by M. Merleau-Ponty.--The phenomenology of perception: perceptual implications, by A. Gurwitsch.--The expression of thinking, by E. W. Straus.--The concept of group and the theory of perception, by E. Cassirer.--Norm and pathology of I-world relations, by E. W. Straus.--The metaphysical in man, by M. Merleau-Ponty.--Cultural differences in the perception of geometric illusions, by M. H. Segall, D. T. Campbell, and M. J. Herskovits.--The interpretive cortex, by W. Penfield.--Recovery from early blindness: a case study, by R. L. Gregory and J. G. Wallace.--Visual disturbances after perceptual isolation, by W. Heron, B. K. Doane, and T. H. Scott. (shrink)

John Corcoran and George Boger. Aristotelian logic and Euclidean geometry. Bulletin of Symbolic Logic. 20 (2014) 131. -/- By an Aristotelian logic we mean any system of direct and indirect deductions, chains of reasoning linking conclusions to premises—complete syllogisms, to use Aristotle’s phrase—1) intended to show that their conclusions follow logically from their respective premises and 2) resembling those in Aristotle’s Prior Analytics. Such systems presuppose existence of cases where it is not obvious that the conclusion follows from the premises: (...) there must be something deductions can show. Corcoran calls a proposition that follows from given premises a hidden consequence of those premises if it is not obvious that the proposition follows from those premises. By a Euclidean geometry we mean an extended discourse beginning with basic premises—axioms, postulates, definitions—1) treating a universe of geometrical figures and 2) resembling Euclid’s Elements. There were Euclidean geometries before Euclid (fl. 300 BCE), even before Aristotle (384–322 BCE). Bochenski, Lukasiewicz, Patzig and others never new this or if they did they found it inconvenient to mention. Euclid shows no awareness of Aristotle. It is obvious today—as it should have been obvious in Euclid’s time, if anyone knew both—that Aristotle’s logic was insufficient for Euclid’s geometry: few if any geometrical theorems can be deduced from Euclid’s premises by means of Aristotle’s deductions. Aristotle’s writings don’t say whether his logic is sufficient for Euclidean geometry. But, there is not even one fully-presented example. However, Aristotle’s writings do make clear that he endorsed the goal of a sufficient system. Nevertheless, incredible as this is today, many logicians after Aristotle claimed that Aristotelian logics are sufficient for Euclidean geometries. This paper reviews and analyses such claims by Mill, Boole, De Morgan, Russell, Poincaré, and others. It also examines early contrary statements by Hintikka, Mueller, Smith, and others. Special attention is given to the argumentations pro or con and especially to their logical, epistemic, and ontological presuppositions. What methodology is necessary or sufficient to show that a given logic is adequate or inadequate to serve as the underlying logi of a given science. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Reviewed by:Method in Ancient PhilosophyDavid K. GliddenJyl Gentzler, editor. Method in Ancient Philosophy. Oxford: Clarendon Press, 1998. Pp. viii + 398. Cloth, $72.00.The fifteen papers in this collection constitute revisions of conference proceedings and reflect the varied interests of participants. The ensemble exhibits a thoroughly modern methodology. Whatever and however various ancient methods of philosophy may have been, in Anglo-American scholarship it is standard practice to first address established (...) scholarly interpretations as the primary entry point to critical discussionóoften displacing antiquity with a critical vocabulary of philosophical modernity. Scholars may come to understand each other better, but at the risk of asking the wrong questions or sacrificing ancient texts themselves as mere means of producing papers.Most scholars are progressives. They believe philosophy has advanced past the comparatively primitive wisdom of antiquity, and so such scholars feel perfectly entitled to make better sense of ancient texts, by patiently explaining what the ancients would have meant had they only been able to get it right. There are, of course, exceptions. And some papers in this collection suggest deeper faith in our philosophic fathers. So, the battle between the ancients and the moderns is joined once more, between those who would adorn their papers with footnotes for their peers and those who would attempt more anthropological an inquiry into ancient philosophic practices.Ian Mueller and Robert Bolton each address the same passage in Plato's Phaedo, both beginning with an article from Vlastos, first published in 1969. Mueller thoughtfully explores three different yet related accounts of what we might call scientific method in explaining Plato's views on natural change. Bolton wonders whether scholars are asking the wrong questions. Patricia Curd attempts a progressivist account of Eleatic thought, notwithstanding her recognition of the paucity of ancient sources. Complete with elaborately numbered sentences, Gail Fine focuses primarily on Burnyeat (1976) on Plato on Protagoras. Constance Meinwald presents a rather near-sighted account of two passages in the Philebus that employ the peras-apeiron distinction, with a view toward Plato's allegedly modernist mathematization of understanding. Lesley Brown revisits five pages of the Sophist that were hotly debated in the 1960s. With charity and elegance, she offers several plausible solutions to puzzles posed by previous scholars. Sometimes time smoothes over differences.A. A. Long's essay on Plato's presentation of Socrates in the Theaetetus might appear more philosophically anthropological. Yet Long reveals progressive sympathies, suggesting that Plato dispatches Socrates in the Theaetetus, so as to prepare the way for a more rigorously academic form of philosophizing, such as that exhibited in the Sophist. [End Page 111] In this way, Long speculates, Plato abandoned practical ethics for the academic life of research, so familiar to university professors and conference participants. It might be hard to square such speculation with Plato's Laws and the reception of Plato's writings among his own contemporaries. Still, Socrates' shifting role in Plato's dialogues is well worth pondering.By comparison, T. H. Irwin's contribution is wonderfully old-fashioned. His paper addresses the background knowledge to be presumed by ancient readers of Plato's dialogues and how that knowledge is artfully put to use in Plato's depiction of Socrates' reflections on the unity of virtue. By speculating on Plato's relation to his ancient readers, Irwin displaces many modernist preoccupations, though not without himself falling victim to that peculiar scholarly obsession of dating Plato's dialogues by their doctrines.With characteristic conservatism, Gisela Striker cautions scholars not to over-read Aristotle's Prior Analytics. While that extraordinary work may have deep implications for the history of formal logic, it probably was instead intended to be part of a general account of argument. In a similar vein, Charlotte Witt attempts to rescue Aristotle from scholars who would delimit Aristotle's multifarious uses of the "for the sake of" explanation, which altogether pervade his metaphysics, physics, biology and ethics. Yet, Witt soon finds herself competing in a contest over interpretive distinctions, a sport that will certainly never capture Aristotle's own authorial intentions.Facing another mass of scholarship, in this case on Aristotle's dialectic, C. D. C. Reeve sensibly attempts to... (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Myth and Investigation in Oedipus RexPeter T. Koper (bio)René Girard's rich interpretations of Attic drama include his discussion in Violence and the Sacred of the sacrificial and reciprocal nature of the mythic violence that underlies Oedipus Rex. "In the myth, the fearful transgression of a single individual is substituted for the universal onslaught of reciprocal violence. Oedipus is responsible for the ills that have befallen his people" (Girard 1977, (...) 77). Girard sees that "the tragedian's version of the Oedipus story differs radically from the myth" (72). The paradigmatic "exchanges of mutual incriminations" (72) between Oedipus and Teiresias raise the question of "whether the accusation [by Teiresias] is simply an act of reprisal arising from the hostile exchange of a tragic debate" (71) rather than a prophetic truth. The play is an investigation of killing. In the myth, the killer is Oedipus, "unequivocally" (72). How Sophocles's play departs from the myth, whether the play is an investigation that confirms the claims of the myth or whether it dramatizes the persecution of an innocent pharmakos is a question Girard leaves suspended, noting that Oedipus cannot be "both incestuous son and parricide and at the same time pharmakos" (122), since a scapegoat is by definition an innocent, chosen arbitrarily. Sandor Goodhart pursued the possibility that Oedipus "may not have killed Laius" (56) in a 1978 article, and Girard returned to the matter in The Scapegoat in 1986. Goodhart's case is based on the report of the surviving servant that Laius was killed by robbers.The servant's account, if accurate, exonerates Oedipus, who was alone when, as he himself reports, he killed every member of a group that included at least three travelers (Sophocles 1960a, 801–834; see Jebb 1893, 150; and Kammerbeck 1967, 164–65) at a "place where three roads meet" (Sophocles 1960a, 716). Oedipus, seeking the murderer of Laius, is worried by Jocasta's account of Laius's death because it reminds him of a fight he himself has had at that place. But Jocasta assures Oedipus that the servant who returned to Thebes and reported the killings said that they were done by robbers. If this is true, then Oedipus is indeed innocent of the charge levied against him by [End Page 87] Teiresias. As the next step in his effort to learn the truth, Oedipus immediately sends for the servant whose testimony appears, at this stage of Oedipus's thinking, to be decisive, for "one man cannot be the same as many" (1960a, 845). When the servant finally arrives, he is never asked the crucial question about the number of murderers. Instead, he is asked to confirm that he did give an infant child to a servant of the king of Corinth instead of abandoning him on the hillside of Mt. Cithaeron as he had been ordered to do. In the usual interpretation of the play, this omission is not decisive. Events have overtaken the investigation, and Oedipus is now not concerned with the identity of the murderer of Laius, or even with whether Oedipus is the murderer (Kammerbeck 1967, 22). He is, rather, concerned with who he is, and, explicitly, with the confirmation of his parricide and incest.Goodhart holds that the discrepancy between the servant's account and that of Oedipus is a decisive indication of Sophocles's intention in the play. In this view, the play uses a traditional myth in which Oedipus kills his father, marries his mother, and then rules Thebes, but the play is not a development of that myth into a heroic intellectual quest in which a man who is the paradigm of the Greek enlightenment pursues and learns the truth. It is rather a play about ambiguity and the impossibility of knowledge. "Rather than an illustration of the myth, the play is a critique of mythogenesis, an examination of the process by which an arbitrary fiction comes to assume the value of truth" (Goodhart 1996, 35). The arbitrary fiction in this case is the opinion that Oedipus killed Laius. A community and an individual, in the midst of the plague, hear a prophecy. They believe it. One individual is the source of the city... (shrink)

Both the concept of a Darwinian tree of life (TOL) and the possibility of its accurate reconstruction have been much criticized. Criticisms mostly revolve around the extensive occurrence of lateral gene transfer (LGT), instances of uptake of complete organisms to become organelles (with the associated subsequent gene transfer to the nucleus), as well as the implications of more subtle aspects of the biological species concept. Here we argue that none of these criticisms are sufficient to abandon the valuable TOL concept (...) and the biological realities it captures. Especially important is the need to conceptually distinguish between organismal trees and gene trees, which necessitates incorporating insights of widely occurring LGT into modern evolutionary theory. We demonstrate that all criticisms, while based on important new findings, do not invalidate the TOL. After considering the implications of these new insights, we find that the contours of evolution are best represented by a TOL. (shrink)

Purpose. The purpose of the study is to show the connection of romanticism with the anthropological doctrine that goes back to Hegelianism and Kantianism, and at the same time – with the concepts of the future, structuralism and postmodernism. Theoretical basis. The man is a central figure of the Romantic literary, therefore it makes sense to single out romantic human anthropological doctrine and the image of man associated with a specific historical and cultural era called the "epoch of romanticism"; to (...) show that many romantic philosophical positions remained relevant to the basic foundations of contemporary anthropological research and coincide with it in analytical and critical thinking about a man, a person, his historical and evolutionary fate. Originality. The romantic worldview determined the specifics of anthropological discourse, both logical and illogical, remaining symbols and attaching, as for example, a real historical anecdote, a popular history, a philosophical thought, a myth, a famous literary episode and the arts multiplied by creative inspiration and imagination. This tendency determined the fragmentation of thinking and the scientific image of man as a dual being, nevertheless, presented and described in all the variety of relations with the world and with himself, that allows us to call this area of thought "the romantic human science". Conclusions. Structural analysis of numerous romantic texts allows us to draw the following conclusion: with mythopoetic imagery and anthropological thought about a man, romantic writers introduced the reader to any wisdom, to philosophical understanding of their human essence, to past and modern teachings, in a way processed antique, medieval and enlightening views, in which an important place was given to reflections on the place of man in nature, society, and history. Correlating the well-known statements about a person as a descendant of the "old Adam", "person", "personality", "soul", with the modern idea of historical and social development, about the evolution of the consciousness of a person who revealed himself as an individual in modern times, with scientific and aesthetic views, the writers of the first half of the XIX century gave romantic thought anthropological meaning and, in fact, laid the foundations of historical, social, psychological, cultural and psychoanalytic anthropology. (shrink)

The essence of temporal universe creation is that any analytical solution has to comply with the boundary condition of our universe; dimensionality and causality constraints. The essence of this book is to show that everything has a price within our temporal (t > 0) universe; energy and time.

The research is devoted to the morphology that V.N. Ilyin developed in the work Static and Dynamics of Pure Form and other archival texts. Morphology is central to the philosophy of V.N. Ilyin, but it remains an unexplored subject. The article’s author explores the morphology of the philosopher from a historical and philosophical point of view. In addition to apparent influences (G.W. Leibniz, E. Husserl, N. Lossky), the article’s author revealed the connection of V.N. Ilyin’s ideas with the history of (...) Western European philosophy and his attitude to medieval thinkers. The author considered how V.N. Ilyin understood and assessed his modern philosophy and its results by the middle of the twentieth century. V.N. Ilyin especially paid attention to phenomenology and its connection with morphology, analyzing phenomenology's influence on existential philosophy. In addition to phenomenology, V.N. Ilyin highly appreciated the intuitism of H. Bergson and N. Lossky. The third main philosophical direction in the twentieth century for V.N. Ilyin was religious philosophy (Neo-Thomists and followers of H. Bergson), which aimed at creating axiology, a new system of values. V.N. Ilyin sought to combine various philosophical ideas in the project of morphology based on logic and scientific methodology. He stated the need to reform formal logic and create “metalogic” that would be more consistent with the philosophical tasks of the twentieth century. The morphology of V.N. Ilyin is based on the idea of synthesis and focuses on creating universal science. The comparison of various philosophical ideas of the twentieth century with morphology makes it possible to understand better his philosophical worldview, the course of his reflections, and the meaning of the morphological project. (shrink)

A scholium in codex Vaticanus graecus 156 provides evidence that Cassius Dio's Roman History once contained an explicit reference to the ludi saeculares of a.d. 204, something that has been denied in recent scholarship.

Information theory and statistical mechanics.

Recoiling from the power that Athenian democracy placed in the hands of the poor, the founding fathers of the United States took Athens as primarily an anti-model, whereas nineteenth-century defenders of slavery found Athens a very congenial model indeed, seeming as it did to lend a mantle of legitimacy to an unspeakable practice. After a “honeymoon period” in which democracy was idealized as the only legitimate form of government, now at the outset of the twenty-first century the alliance of democracy (...) with a capitalism that often proves heartless to the less fortunate has raised some troubling questions about democracy itself. Despite its small size, classical Athens offers valuable guidance for tempering current difficulties in both the United States and elsewhere by adopting and adapting the selection of some officials by sortition, direct election by popular vote of elected officials, a rigorous system of accountability, and the fostering of civic and community values. (shrink)

This chapter argues for the History of England’s importance in Hume’s overall achievement. The chapter describes the History’s genesis, reception, methods, and aims. In the role of historian, Hume shared with the ancients the assumption that history is an elevated genre functioning as the “Mistress of Wisdom.” Yet this long work is more notable for historiographical innovation. Like William Robertson and Edward Gibbon, Hume wrote conjectural or philosophical history. Like Machiavelli, Voltaire, and Montesquieu, Hume wrote civil or cultural history, including (...) detailed information on political events, law, commerce, and manners. In a larger sense, the History demonstrates a great philosopher leaving his study to deal with that practical, sometimes intractable world outside the study. A priori reasoning is tested against that a posteriori reality provided by historical evidence. Thus, in writing the History, Hume became an empiricist in an almost literal sense. (shrink)

Scientists recognize the necessity of imagination for solving tough problems. But how does the cognitive faculty responsible for daydreaming help in solving scientific problems? Philosophers claim that imagination is informative only when it is constrained to be maximally realistic. However, using a case study from space science, we show that scientists use imagination intentionally to break reality-oriented constraints. To do this well, they first target low-confidence constraints, and then higher-confidence constraints, until a plausible solution is found. This paper exemplifies a (...) new approach to epistemology of imagination that focuses on sets of imaginings (rather than individual imaginings), and responsible (rather than reliable) imaginings. (shrink)

Though assumptions about language underlie all bioethical work, the field has rarely partaken of theories of language. This article encourages a more linguistically engaged bioethics. We describe the tacit conception of language that is frequently upheld in bioethics—what we call the representational view, which sees language essentially as a means of description. We examine how this view has routed the field’s theories and interventions down certain paths. We present an alternative model of language—the pragmatic view—and explore how it expands and (...) clarifies traditional bioethical concerns. To lend concreteness, we apply the pragmatic view to a pervasive concept in bioethics and adjacent fields: decision making. We suggest that problems of the decision-making approach to bioethical issues are grounded in adherence to the representational view. Drawing on empirical work in surgery and critical care, we show how the pragmatic view productively reframes bioethical questions about how medical treatments are pursued. (shrink)

The rise and spectacular fall of the friendship between the two great philosophers of the eighteenth century, barely six months after they first met, reverberated on both sides of the Channel. As the relationship between Jean-Jacques Rousseau and David Hume unraveled, a volley of rancorous letters was fired off, then quickly published and devoured by aristocrats, intellectuals, and common readers alike. Everyone took sides in this momentous dispute between the greatest of Enlightenment thinkers. In this lively and revealing book, Robert (...) Zaretsky and John T. Scott explore the unfolding rift between Rousseau and Hume. The authors are particularly fascinated by the connection between the thinkers’ lives and thought, especially the way that the failure of each to understand the other—and himself—illuminates the limits of human understanding. In addition, they situate the philosophers’ quarrel in the social, political, and intellectual milieu that informed their actions, as well as the actions of the other participants in the dispute, such as James Boswell, Adam Smith, and Voltaire. By examining the conflict through the prism of each philosopher’s contribution to Western thought, Zaretsky and Scott reveal the implications for the two men as individuals and philosophers as well as for the contemporary world. (shrink)

The rise and spectacular fall of the friendship between the two great philosophers of the eighteenth century, barely six months after they first met, reverberated on both sides of the Channel. As the relationship between Jean-Jacques Rousseau and David Hume unraveled, a volley of rancorous letters was fired off, then quickly published and devoured by aristocrats, intellectuals, and common readers alike. Everyone took sides in this momentous dispute between the greatest of Enlightenment thinkers. In this lively and revealing book, Robert (...) Zaretsky and John T. Scott explore the unfolding rift between Rousseau and Hume. The authors are particularly fascinated by the connection between the thinkers’ lives and thought, especially the way that the failure of each to understand the other—and himself—illuminates the limits of human understanding. In addition, they situate the philosophers’ quarrel in the social, political, and intellectual milieu that informed their actions, as well as the actions of the other participants in the dispute, such as James Boswell, Adam Smith, and Voltaire. By examining the conflict through the prism of each philosopher’s contribution to Western thought, Zaretsky and Scott reveal the implications for the two men as individuals and philosophers as well as for the contemporary world. (shrink)

In this paper, I attempt to explain one of the most controversial views attributed to the Stoic Chrysippus: that the impossible can follow from the possible. My solution finds in Chrysippus a distinction later made by the medieval logician John Buridan: that between being possible (there being a state of affairs that may occur) and being possibly-true (there being some proposition whose truth-conditions are that state of affairs). Buridan and Chrysippus have radically opposing views on the nature of propositions. What (...) their conceptions share is the conclusion that at least some propositions must be contingent beings. They argue for this while maintaining a rigorous commitment to the view that propositions are strictly bivalent. In 2. I explain the Chrysippean passage in terms of a distinction Buridan makes explicitly. In 3. I show how the distinction follows implicitly from the Stoic theory of quantification. In 4. I compare the modality with other aspects of Stoic logic. In 5. I discuss how the distinction behaves in the future tense. (shrink)