The article concerns itself with normative aspects of public health in light of recent debates. It starts out by introducing a few terminological and conceptual distinctions that set the stage for the subsequent discussion. This is followed by critical remarks on two proposals for developing an adequate public health ethics and the way that the growing health inequalities observed in much of the OECD-world are dealt with in parts of the pertinent literature. The article concludes with a cautionary note on (...) the ‘dangers’ of over-identification with a public health agenda and of over-moralization of empirical findings that give cause for concern. (shrink)

This paper deals with a problem which has received a great deal of attention in the ethical literature, but about which very little is known empirically: the selection of recipients for organs in transplant medicine. Based on a larger study, it is shown how this problem is practically resolved in one European country, Germany. It is demonstrated that most of the criteria used to determine recipients are non-medical in nature, even though they generally tend to be rationalized in medical terms. (...) Moreover, the choice of criteria depends as much on prognostic considerations as on personal indiosyncrasies and values held by individual physicians who are in charge at the various programs. Several examples of the extremely diverse policies in which this results are presented. (shrink)

Der Aufsatz widmet sich dem Wohlfahrtseffekt öffentlicher Ausgaben unter besonderer Berücksichtigung der Bereiche Gesundheitswesen und Bildungswesen. Ausgangspunkt ist die Feststellung des bemerkenswert geringen Ertrags hoher Aufwendungen für öffentliche Gesundheit, der insbesondere im Vergleich von Ländern mit teils deutlich variierenden Gesundheitsbudgets auffällt. Da das Gesundheitswesen aufgrund der Opportunitätskostenproblematik mit anderen Bereichen sozialpolitischer Sicherheitsgewähr um knappe öffentliche Mittel konkurriert, ist darauf zu achten, dass deren Allokation bestmöglich optimiert wird. Im deutschen Fall mit seinem ungewöhnlich hohen Anteil öffentlicher Gesundheitsausgaben legt das eine Verschiebung (...) der Prioritäten zugunsten des Bildungswesens nahe, wofür neben potentiellen Verbesserungen des Gesundheitsstatus der Bevölkerung und funktionalen, die gesellschaftliche Integration betreffenden Erwägungen auch solche der sozialen Gerechtigkeit sprechen. Ein Programm zur Reformierung des Gesundheitswesens, das diesen Leitlinien folgt, wird skizziert. (shrink)

Der Aufsatz widmet sich dem Wohlfahrtseffekt öffentlicher Ausgaben unter besonderer Berücksichtigung der Bereiche Gesundheitswesen und Bildungswesen. Ausgangspunkt ist die Feststellung des bemerkenswert geringen Ertrags hoher Aufwendungen für öffentliche Gesundheit, der insbesondere im Vergleich von Ländern mit teils deutlich variierenden Gesundheitsbudgets auffällt. Da das Gesundheitswesen aufgrund der Opportunitätskostenproblematik mit anderen Bereichen sozialpolitischer Sicherheitsgewähr um knappe öffentliche Mittel konkurriert, ist darauf zu achten, dass deren Allokation bestmöglich optimiert wird. Im deutschen Fall mit seinem ungewöhnlich hohen Anteil öffentlicher Gesundheitsausgaben legt das eine Verschiebung (...) der Prioritäten zugunsten des Bildungswesens nahe, wofür neben potentiellen Verbesserungen des Gesundheitsstatus der Bevölkerung und funktionalen, die gesellschaftliche Integration betreffenden Erwägungen auch solche der sozialen Gerechtigkeit sprechen. Ein Programm zur Reformierung des Gesundheitswesens, das diesen Leitlinien folgt, wird skizziert. (shrink)

This article critically engages a recent essay Jeffrey Alexander has published on ‘societalization’, whose conceptualization it finds problematic; first, because in contrast to the impression conveyed by the essay, the term itself is anything but new (as shown in a summary of six theories of societalization which precede Alexander’s by decades, in two cases, by more than a century), and, second, because the way Alexander employs the term is highly aporetic, while also being emblematic of much deeper problems that afflict (...) the whole discipline. Following a reconstruction of the term’s morphology and the transmutations it underwent during its gradual incorporation into the English language, the article identifies an undertheorized concept of society as the root cause behind the difficulties into which Alexander maneuvers himself. It concludes with a brief sketch of an alternative that can contribute to overcoming these difficulties. (shrink)

Definition of the problem: The article discusses the ways in which sociological analyses can contribute to the problem of a just allocation of scarce donor organs.Arguments: It is argued that this contribution consists primarily in the demonstration of the ethical, rather than medical nature of the problem itself. Only if its ethical nature is acknowledged will it be possible to come to a proper understanding of the several dilemmas involved and to consider adequate means for handling them.

In the mid-1980s, German social democracy was revived like a Phoenix from the ashes. In the individual federal states, it proved its governing capability which had been lost in the final years of the Schmidt Administration: The Social Democrats not only controlled the city-states of Bremen and Hamburg widi an absolute majority, but were able to win die 1985 elections so overwhelmingly, both in the largest state of North Rhine-Westphalia and also in Saarland, that they were not forced to (...) form any coalitions. But where die Social Democrats needed a partnership, as in Hesse, diey showed diat they would wager a red-green coalition. In special political areas, the Opposition made dramatic changes, above all in peace and security policy. (shrink)

Friedrich Nietzsche, den Gottfried Benn als das "grosste Ausstrahlungsphanomen der Geistesgeschichte" bezeichnete, steht im Zentrum dieses Buches. Es enthalt die Vortrage der Ringvorlesung, welche die Freiburger Forschungsstelle "Nietzsche-Kommentar" zum 100. Geburtstag der Heidelberger Akademie der Wissenschaften organisierte. - In der konstruktiven Auseinandersetzung mit Nietzsche beleuchten die Aufsatze Nietzsches Bedeutung als Leitfigur moderner Lebensphilosophie, Kulturdiagnose und Anthropologie. Nietzsches Kritik an der philosophischen Tradition, sein Konzept der Umwertung, seine Psychologie, sein Geschichtsdenken, seine Beziehung zu Darwin, Schopenhauer, Wagner und Heidegger, seine Lyrik sowie (...) die Charakteristika seines Stils gehoren zum breitgefacherten Themenspektrum.Der Band enthalt Beitrage von Dieter Borchmeyer, Gunter Figal, Hans-Martin Gauger, Volker Gerhardt, Katharina Gratz, Lore Huhn, Helmuth Kiesel, Ludger Lutkehaus, Klaus Monig, Barbara Neymeyr, Annemarie Pieper, Jochen Schmidt und Andreas Urs Sommer. (shrink)

Das Buch gibt einen Überblick über die Arbeiten von Hans Albert und behandelt ausgewählte Konsequenzen seines Werks für die Philosophie des Kritischen Rationalismus und ihre Anwendungen in Gebieten der Soziologie, Wirtschaftswissenschaften, Rechtswissenschaften und weiteren Wissenschaften.

The modern republican history of Turkey and its relation with the question of ethnic diversity could be understood via the tension between the processes of system integration and social integration. This article, based on Jürgen Habermas’ conceptual framework, draws the sources of such tension with reference to the Kurdish identity in Turkey since the early republican era. For this purpose, from the 1920s to the 2000s, policies and discourses of system integration aiming at a certain degree of ethnic homogenization to (...) eliminate ‘possible threats’ to territorial integrity and national unity are discussed in detail. While system integration processes reflect an exclusionary and assimilative-securitist logic of state practices regarding the Kurdish question, this article argues that the Kurdish challenge to republicanism and to its system integration logic promises more for the dynamics of social integration. Especially since the 1990s, while processes of system integration are still in force; national, regional and diasporic achievements of Kurdish politics and its call for a democratic transformation of the republic based on decentralist, participatory and multiculturalist values have become much more visible. This new focus on democratic transformation demands more for social integration through internalization of roles as well as through promotion of an active communication between citizens by raising the claims of active participation to social and political spheres as well as by making identity visible in different aspects of socio-cultural life. Degree of social integration and its success vis-à-vis system integration will be decisive in the democratic transformation of Turkey in the future. (shrink)

The role of uncertainty within an organization’s environment features prominently in the business ethics and management literature, but how corporate investment decisions should proceed in the face of uncertainties relating to the natural environment is less discussed. From the perspective of ecological economics, the salience of ecology-induced issues challenges management to address new types of uncertainties. These pertain to constraints within the natural environment as well as to institutional action aimed at conserving the natural environment. We derive six areas of (...) ecology-induced uncertainties and propose ecology-driven real options as a conceptual approach for systematically incorporating these uncertainties into strategic management. We combine our results in an integrative investment framework and illustrate its application with the case of carbon constraints. (shrink)

Friedrich Engels: Herrn Eugen Dührings Umwälzung der Wissenschaft. (Anti-Dühring) Lesefreundlicher Großdruck in 16-pt-Schrift Großformat, 210 x 297 mm Berliner Ausgabe, 2019 Durchgesehener Neusatz mit einer Biographie des Autors bearbeitet und eingerichtet von Theodor Borken Erstdruck in: Vorwärts (Leipzig), 3.1.1877 - 7.7.1878. Erste Buchausgabe, Leipzig 1878. Der Text folgt der letzten von Engels durchgesehenen und vermehrten Ausgabe, Stuttgart (J.H.W. Dietz) 1894. Textgrundlage ist die Ausgabe: Karl Marx, Friedrich Engels: Werke. Herausgegeben vom Institut für Marxismus-Leninismus beim ZK der SED, 43 Bände, Band (...) 20, Berlin: Dietz-Verlag, 1962. Umschlaggestaltung von Thomas Schultz-Overhage. Gesetzt aus der Minion Pro, 16 pt. Henricus Edition Deutsche Klassik UG (haftungsbeschränkt). (shrink)

Proteoglycan 4 (PRG4), first identified in synovial fluid, is an extracellular matrix structural protein in the joint implicated in reducing shear at the cartilage surface as well as controlling adhesion‐dependent synovial growth and regulating bulk protein deposition onto the cartilage. However, recent evidence suggests that it can bind to and effect downstream signaling of a number of cell surface receptors implicated in regulating the inflammatory response. Therefore, we pose the hypothesis: Does PRG4 regulate the inflammatory response and maintain tissue homeostasis? (...) Based on these novel findings implicating PRG4 as an inflammatory signaling molecule, we will present and discuss several hypotheses regarding potential mechanisms by which PRG4 may be able to regulate inflammation. If future studies can demonstrate that PRG4 is a potent inflammatory mediator, this will change current paradigms in the musculoskeletal and ophthalmological fields regarding the how the inflammatory microenvironment is regulated in these tissues and potentially others. (shrink)

So-called ‘anonymous’ tissue samples are widely used in research. Because they lack externally identifying information, they are viewed as useful in reconciling conflicts between the control, privacy and confidentiality interests of those from whom the samples originated and the public (or commercial) interest in carrying out research, as reflected in ‘consent or anonymise’ policies. High level guidance documents suggest that withdrawal of consent and samples and the provision of feedback are impossible in the case of anonymous samples. In view of (...) recent developments in science and consumer-driven genomics the authors argue that such statements are misleading and only muddle complex ethical questions about possible entitlements to control over samples. The authors therefore propose that terms such as ‘anonymised’, ‘anonymous’ or ‘non-identifiable’ be removed entirely from documents describing research samples, especially from those aimed at the public. This is necessary as a matter of conceptual clarity and because failure to do so may jeopardise public trust in the governance of large scale databases. As there is wide variation in the taxonomy for tissue samples and no uniform national or international standards, the authors propose that a numeral-based universal coding system be implemented that focuses on specifying incremental levels of identifiability, rather than use terms that imply that the reidentification of research samples and associated actions are categorically impossible. (shrink)

Die Reformation von 1517 wird oft genug monumentalisch als Auftakt der Moderne erinnert. Demgegenüber setzt Nietzsches Kritik an der Revitalisierung des Christentums durch Luther und die Gegenreformation einen Gegenakzent. Wer sich in der Vergangenheit auf dieses Thema eingelassen hat, verfolgte oft nicht bloß gelehrte Interessen, sondern eine eigene weltanschauliche Agenda. Während manche Luther gegen die Kritik Nietzsches verteidigten, sahen andere im ‚Tod Gottes’ die konsequente Fortsetzung des reformatorischen Zerstörungswerkes. Zugleich erkannte Nietzsche die Reformation als fragwürdiges und folgenreiches Ereignis, rühmte die (...) Sprachgewalt Luthers und strebte selbst nach einer grundlegenden Umgestaltung der Kultur. Das Thema ist daher noch immer nicht nur von historischem, sondern auch von aktuellem Interesse. Was lässt sich an der Beschäftigung Nietzsches mit der Reformation über Nietzsche, über die Reformation, über das Christentum und über unsere Gegenwart lernen? Diesen und weiteren Fragen widmen sich Volker Gerhardt, Beatrix Himmelmann, Gerald Hödl, Sebastian Kaufmann, Dagmar Kiesel, Duncan Large, Enno Rudolph, Michael Schmidt-Salomon, Christoph Türcke und weitere Forscher aus aller Welt. (shrink)

ArgumentThis article uses four historical case studies to address epistemological issues related to the animal model of human diseases and its use in medical research on human diseases. The knowledge derived from animal models is widely assumed to be highly valid and predictive of reactions by human organisms. In this contribution, I use three significant historical cases of failure (ca. 1890, 1960, 2006), and a closer look at the emergence of the concept around 1860/70, to elucidate core assumptions related to (...) the specific practices of animal-human knowledge transfer, and to analyze the explanations provided by historical actors after each of the failures. Based on these examples, I argue that the epistemological status of the animal model changed from that of a helpful methodological tool for addressing specific questions, but with precarious validity, to an obligatory method for the production of strong knowledge on human diseases. As a result, there now exists a culture of biomedical research in human disease that, for more than a century, has taken the value of this methodological tool as self-evident, and more or less beyond question. (shrink)

ZusammenfassungDer Wiesbadener Internistenkongress 1949 war Bühne für eine heftige Kontroverse zu Fragen der Methodik, Epistemologie und Evidenz in der psychosomatischen Medizin. Paul Martini, Internist und Protagonist methodisch durchgeführter klinischer Studien, kritisierte in diesem Kontext die Methodik psychosomatischer Wissensproduktion und bezweifelte die Validität der postulierten Einsichten. Ausgehend von dieser Kontroverse rekonstruiert der Beitrag die Formierung und Durchführung eines Experimentalsystems zur Entstehung der Hypertonie, in welchem der Internist und Psychosomatiker Thure von Uexküll somatische Variablen, die Subjektivität des Patienten, seine Biografie und seinen (...) sozialen Kontext zu integrieren versuchte. Die Deutungen der Patienten hatten in diesem Experimentalsystem einen privilegierten Status. Empirische Belege, Nachvollziehbarkeit und Reproduzierbarkeit – Forderungen, die Martini 1949 formuliert hatte – waren für Uexküll elementare Kriterien für relevantes und valides Wissen. (shrink)

The purpose of Key Approaches to Biblical Ethics is to address fundamental as well as practical questions of methodology in examining the ethical material of the Bible. Sixteen scholars of international reputation, most of them leaders in the field of biblical ethics, discuss questions of biblical interpretation from the perspectives of the Hebrew Bible and New Testament ethics in close dialogue with one another. In the present volume both established and new approaches to biblical ethics are presented and discussed. The (...) result is a volume of unprecedented scholarly interaction that provides key insights into issues of biblical ethics that play a significant role both for biblical interpretation as well as for methodological questions in Jewish and Christian ethics today. (shrink)

Seit Niccolo Machiavellis Principe (postum) im Jahre 1532 veroffentlicht worden ist, haben sich Generationen von Philosophen, Theologen und Historikern, aber auch von Politikern mit den Thesen des Florentiners auseinandergesetzt. Die Bucher zur Rezeption Machiavellis fullen inzwischen ganze Bibliotheken. Kann man heute - fast funfhundert Jahre spater - noch etwas Neues dazu beitragen? Vielleicht gelingt dies, indem der machiavellische Machtstaat aus interdisziplinarer Perspektive im Spiegel der Zeit beleuchtet wird. Die negative Sicht der Ratschlage Machiavellis an einen neuen Fursten ist mit dem (...) Begriff "Machiavellismus" gebrandmarkt worden. Die Frage, ob der Florentiner selbst ein Machiavellist war, ist heute freilich eher zu verneinen. Die mit dem Schlagwort verbundenen Vorurteile erweisen sich jedoch als resistent gegenuber jedem Gegenargument. Den unterschiedlichen, meist zeitbedingten Interpretationen der Lehre Machiavellis, mit denen der Interpret oft genug nur seine eigenen Anschauungen begrundet, soll in diesem Band nachgespurt werden. (shrink)

The acoel worm Symsagittifera roscoffensis, an early offshoot of the Bilateria and the only well‐studied marine acoel that lives in a photosymbiotic relationship, exhibits a centralized nervous system, brain regeneration, and a wide repertoire of complex behaviors such as circatidal rhythmicity, photo/geotaxis, and social interactions. While this animal can be collected by the thousands and is studied historically, significant progress is made over the last decade to develop it as an emerging marine model. The authors here present the feasibility of (...) culturing it in the laboratory and describe the progress made on different areas, including genomic and tissue architectures, highlighting the associated challenges. In light of these developments, and on the ability to access abundant synchronized embryos, the authors put forward S. roscoffensis as a marine system to revisit questions in the areas of photosymbiosis, regeneration, chronobiology, and the study of complex behaviors from a molecular and evolutionary perspective. (shrink)